Diosbulbin B-induced liver injury in mice and its mechanism

Human and Experimental Toxicology

Volumn 33, Issue 7, 2014, Pages 729-736

  Ma, Yibo ^a,b   Niu, Chengwei ^a   Wang, Junming ^c   Ji, Lili ^a   Wang, Zhengtao ^a,b  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c HENAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

diosbulbin B; Dioscorea bulbifera L.; hepatotoxicity; oxidative stress

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; DIOSBULBIN B; DITERPENE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; FUSED HETEROCYCLIC RINGS; HERBACEOUS AGENT; MESSENGER RNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL SWELLING; CONTROLLED STUDY; DIOSCOREA BULBIFERA; DRUG STRUCTURE; ENZYME ACTIVITY; GENE EXPRESSION; LIVER CELL; LIVER HEMORRHAGE; LIVER HISTOLOGY; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; ANIMAL; BLOOD; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; LIVER; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; PATHOLOGY; TIME;

ADMINISTRATION, ORAL; ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; DRUG-INDUCED LIVER INJURY; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTATHIONE; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; LIVER; MALE; MALONDIALDEHYDE; MICE, INBRED ICR; OXIDATIVE STRESS; RNA, MESSENGER; TIME FACTORS;

EID: 84903531847     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327113506232     Document Type: Article

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