Buthionine sulfoximine, an inhibitor of glutathione biosynthesis, induces expression of soluble epoxide hydrolase and markers of cellular hypertrophy in a rat cardiomyoblast cell line: Roles of the NF-κB and MAPK signaling pathways

Free Radical Biology and Medicine

Volumn 82, Issue , 2015, Pages 1-12

  Abdelhamid, Ghada ^a   El Kadi, Ayman O S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

MAPKs; NF ?B; sEH

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; BUTHIONINE SULFOXIMINE; EPOXIDE HYDROLASE; GLUTATHIONE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PYRROLIDINE DITHIOCARBAMATE; SOLUBLE EPOXIDE HYDROLASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 1,3 BUTADIENE DERIVATIVE; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; ANTIOXIDANT; EPHX2 PROTEIN, RAT; FLAVONOID; I KAPPA B; NATRIURETIC PEPTIDE PRECURSOR TYPE B, RAT; NF-KAPPAB INHIBITOR ALPHA; NITRILE; PROLINE; PROLINEDITHIOCARBAMATE; RELA PROTEIN, RAT; THIOCARBAMIC ACID DERIVATIVE; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR DISEASE; CELL VIABILITY; DNA BINDING; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE TRANSLOCATION; HYPERTROPHY; IN VITRO STUDY; MARKER GENE; MYOBLAST; NONHUMAN; OXIDATIVE STRESS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CARDIAC MYOBLAST; CARDIOMEGALY; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; HEART FAILURE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY;

RATTUS;

ANIMALS; ANTIOXIDANTS; ATRIAL NATRIURETIC FACTOR; BUTADIENES; BUTHIONINE SULFOXIMINE; CARDIOMEGALY; CELL LINE; CELL SURVIVAL; ENZYME ACTIVATION; EPOXIDE HYDROLASES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GENE EXPRESSION REGULATION; GLUTATHIONE; HEART FAILURE; I-KAPPA B PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MYOBLASTS, CARDIAC; NATRIURETIC PEPTIDE, BRAIN; NF-KAPPA B P50 SUBUNIT; NITRILES; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROLINE; RATS; RNA, MESSENGER; THIOCARBAMATES; TRANSCRIPTION FACTOR RELA; UP-REGULATION;

EID: 84923879239     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.01.005     Document Type: Article

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