Chronic depletion of glutathione exacerbates ventricular remodelling and dysfunction in the pressure-overloaded heart

Cardiovascular Research

Volumn 97, Issue 2, 2013, Pages 282-292

  Watanabe, Yosuke ^a   Watanabe, Kazuhiro ^a   Kobayashi, Tsuyoshi ^a   Saito, Yukio ^a   Fujioka, Daisuke ^a   Nakamura, Takamitsu ^a   Obata, Jun Ei ^a   Kawabata, Kenichi ^a   Mishina, Hideto ^a   Kugiyama, Kiyotaka ^a  

^a UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Cardiomyopathy; Fibrosis; Gene polymorphisms; Heart failure; Oxygen radicals

Indexed keywords

CALCIUM ION; GELATINASE A; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MESSENGER RNA; MYOSIN HEAVY CHAIN BETA; OXYGEN RADICAL; SMAD3 PROTEIN; URIC ACID;

ADULT; AGE; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA PRESSURE; ARTICLE; BODY MASS; BODY WEIGHT; CALCIUM TRANSPORT; CARDIOVASCULAR RISK; CONCENTRATION (PARAMETERS); CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; CORRELATIONAL STUDY; DIABETES MELLITUS; DNA POLYMORPHISM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FIBROBLAST; FIBROGENESIS; GENE EXPRESSION; GENETIC RISK; HEART DILATATION; HEART FAILURE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE FIBROSIS; HEART RATE; HEART VENTRICLE REMODELING; HEART WEIGHT; HUMAN; HUMAN TISSUE; LUNG WEIGHT; MAJOR CLINICAL STUDY; MALE; MICROVASCULATURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; SURVIVAL; SURVIVAL RATE; SYSTOLIC BLOOD PRESSURE; TISSUE HOMOGENATE; TISSUE LEVEL; URIC ACID BLOOD LEVEL;

ANIMALS; CALCIUM; CARDIOMYOPATHY, DILATED; ECHOCARDIOGRAPHY; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HEMODYNAMICS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIUM; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84872581593     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs333     Document Type: Article

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