Type 4 phosphodiesterase enzyme inhibitor, rolipram rescues behavioral deficits in olfactory bulbectomy models of depression: Involvement of hypothalamic-pituitary-adrenal axis, cAMP signaling aspects and antioxidant defense system

Pharmacology Biochemistry and Behavior

Volumn 132, Issue , 2015, Pages 20-32

  Jindal, Ankur ^a   Mahesh, Radhakrishnan ^a   Bhatt, Shvetank ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Behavioral paradigms; Depression; Neurobiological markers; Olfactory bulbectomy; Oxidative stress; Rolipram

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CATALASE; CORTICOSTERONE; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FLUOXETINE; GLUTATHIONE; NITRITE; ROLIPRAM; SUPEROXIDE DISMUTASE;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; DRUG EFFECT; DRUG MECHANISM; ELEVATED PLUS MAZE TEST; HYPERACTIVITY; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LIPID PEROXIDATION; MALE; NITROSATIVE STRESS; NONHUMAN; OLFACTORY BULBECTOMY; OPEN FIELD TEST; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SUCROSE PREFERENCE TEST; TREATMENT DURATION;

EID: 84923870404     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2015.02.017     Document Type: Article

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