How valuable are animal models in defining antidepressant activity?

Human Psychopharmacology

Volumn 16, Issue 1, 2001, Pages 9-21

  Mcintyre, John S ^a  

^a UNITY HEALTH SYSTEM   (United States)

Author keywords

Animal models; Antidepressants; Chronic mild stress; Forced swim; Learned helplessness; Olfactory bulbectomy

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ALPRAZOLAM; AMITRIPTYLINE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; APOMORPHINE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUSPIRONE; CENTRAL STIMULANT AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; CLOMIPRAMINE; CLONIDINE; FLUOXETINE; GEPIRONE; HALOPERIDOL; KETANSERIN; METITEPINE; MONOAMINE OXIDASE INHIBITOR; NEUROLEPTIC AGENT; ONDANSETRON; PINDOLOL; RISPERIDONE; SCOPOLAMINE; SEDATIVE AGENT; SEROTONIN 1 AGONIST; SEROTONIN UPTAKE INHIBITOR; SULPIRIDE; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC MILD STRESS; CLINICAL PRACTICE; CLINICAL RESEARCH; CONTROLLED STUDY; DEPRESSION; DRUG ACTIVITY; DRUG MECHANISM; DRUG SCREENING; FORCED SWIMMING TEST; LABORATORY; LEARNED HELPLESSNESS; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; OLFACTORY BULBECTOMY; PREDICTION; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; STRESS; THEORY; TIME; VALIDATION PROCESS;

EID: 0035100705     PISSN: 08856222     EISSN: None     Source Type: Journal    
DOI: 10.1002/hup.178     Document Type: Article

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