Curcumin inhibits anchorage-independent growth of HT29 human colon cancer cells by targeting epigenetic restoration of the tumor suppressor gene DLEC1

Biochemical Pharmacology

Volumn 94, Issue 2, 2015, Pages 69-78

  Guo, Yue ^a   Shu, Limin ^a   Zhang, Chengyue ^a   Su, Zheng Yuan ^a   Kong, Ah Ng Tony ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Anchorage independent growth; Colorectal cancer; Curcumin; DLEC1; Epigenetics

Indexed keywords

BETA ACTIN; CURCUMIN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 6; HISTONE DEACETYLASE 8; SHORT HAIRPIN RNA; DLEC1 PROTEIN, HUMAN; PRIMER DNA; TUMOR SUPPRESSOR PROTEIN;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; COLONY FORMATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; CPG ISLAND; DEMETHYLATION; DLEC1 GENE; DNA METHYLATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE; UPREGULATION; WESTERN BLOTTING; CELL ADHESION; COLON TUMOR; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETICS; HT 29 CELL LINE; NUCLEOTIDE SEQUENCE; PATHOLOGY; PROMOTER REGION;

BASE SEQUENCE; CELL ADHESION; COLONIC NEOPLASMS; CURCUMIN; DNA METHYLATION; DNA PRIMERS; GENES, TUMOR SUPPRESSOR; HT29 CELLS; HUMANS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84923864187     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.01.009     Document Type: Article

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