메뉴 건너뛰기




Volumn 102, Issue 4, 2007, Pages 1232-1241

The organotellurium compound ammonium trichloro(dioxoethylene-0,0′) tellurate enhances neuronal survival and improves functional outcome in an ischemic stroke model in mice

Author keywords

Apoptosis; Calcium; Caspase; Excitotoxicity; Hydroxynonenal; Tellurium

Indexed keywords

4 HYDROXYNONENAL; AMMONIUM TRICHLORO(DIOXYETHYLENE O,O')TELLURATE; CALCIUM; CASPASE; GLUCOSE; ORGANOTELLURIUM DERIVATIVE;

EID: 34547404713     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04615.x     Document Type: Article
Times cited : (56)

References (52)
  • 1
    • 1842558602 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury
    • Arundine M. Tymianski M. (2004) Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury. Cell Mol. Life Sci. 61, 657 668.
    • (2004) Cell Mol. Life Sci. , vol.61 , pp. 657-668
    • Arundine, M.1    Tymianski, M.2
  • 2
    • 0022483434 scopus 로고
    • Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurologic examination
    • Bederson J. B., Pitts L. H., Tsuji M., Nishimura M. C., Davis R. L. Bartkowski H. (1986) Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 17, 472 476.
    • (1986) Stroke , vol.17 , pp. 472-476
    • Bederson, J.B.1    Pitts, L.H.2    Tsuji, M.3    Nishimura, M.C.4    Davis, R.L.5    Bartkowski, H.6
  • 3
    • 0032005805 scopus 로고    scopus 로고
    • 4-hydroxynonenal, a lipid peroxidation product, inhibits glutamate transport in astrocytes
    • Blanc E. M., Keller J. N., Fernandez S. Mattson M. P. (1998) 4-hydroxynonenal, a lipid peroxidation product, inhibits glutamate transport in astrocytes. Glia 22, 149 160.
    • (1998) Glia , vol.22 , pp. 149-160
    • Blanc, E.M.1    Keller, J.N.2    Fernandez, S.3    Mattson, M.P.4
  • 4
    • 0029884441 scopus 로고    scopus 로고
    • Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia
    • Chen J., Zhu R. L., Nakayama M., Kawaguchi K., Jin K., Stetler R. A., Simon R. P. Graham S. H. (1996) Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia. J. Neurochem. 67, 64 71.
    • (1996) J. Neurochem. , vol.67 , pp. 64-71
    • Chen, J.1    Zhu, R.L.2    Nakayama, M.3    Kawaguchi, K.4    Jin, K.5    Stetler, R.A.6    Simon, R.P.7    Graham, S.H.8
  • 5
    • 0037312886 scopus 로고    scopus 로고
    • Inflammatory mechanisms after ischemia and stroke
    • Danton G. H. Dietrich W. D. (2003) Inflammatory mechanisms after ischemia and stroke. J. Neuropathol. Exp. Neurol. 62, 127 136.
    • (2003) J. Neuropathol. Exp. Neurol. , vol.62 , pp. 127-136
    • Danton, G.H.1    Dietrich, W.D.2
  • 6
    • 0033573874 scopus 로고    scopus 로고
    • Activation of caspase 3 in HL-60 cells exposed to hydrogen peroxide
    • DiPietrantonio A. M., Hsieh T. Wu J. M. (1999) Activation of caspase 3 in HL-60 cells exposed to hydrogen peroxide. Biochem. Biophys. Res. Commun. 255, 477 482.
    • (1999) Biochem. Biophys. Res. Commun. , vol.255 , pp. 477-482
    • Dipietrantonio, A.M.1    Hsieh, T.2    Wu, J.M.3
  • 7
    • 18044379722 scopus 로고    scopus 로고
    • Free radical trapping as a therapeutic approach to neuroprotection in stroke: Experimental and clinical studies with NXY-059 and free radical scavengers
    • Green A. R. Ashwood T. (2005) Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers. Curr. Drug Targets CNS Neurol. Disord. 4, 109 118.
    • (2005) Curr. Drug Targets CNS Neurol. Disord. , vol.4 , pp. 109-118
    • Green, A.R.1    Ashwood, T.2
  • 8
    • 12344331219 scopus 로고    scopus 로고
    • Bone marrow transplantation reveals roles for macrophage/microglia TNF signaling and nitric oxide production in excitotoxic neuronal death
    • Guo Z., Iyun T., Fu W., Zhang P. Mattson M. P. (2004) Bone marrow transplantation reveals roles for macrophage/microglia TNF signaling and nitric oxide production in excitotoxic neuronal death. Neuromolecular Med. 5, 219 234.
    • (2004) Neuromolecular Med. , vol.5 , pp. 219-234
    • Guo, Z.1    Iyun, T.2    Fu, W.3    Zhang, P.4    Mattson, M.P.5
  • 9
    • 0033858805 scopus 로고    scopus 로고
    • Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia
    • Gursoy-Ozdemir Y., Bolay H., Saribas O. Dalkara T. (2000) Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia. Stroke 31, 1974 1980.
    • (2000) Stroke , vol.31 , pp. 1974-1980
    • Gursoy-Ozdemir, Y.1    Bolay, H.2    Saribas, O.3    Dalkara, T.4
  • 10
    • 0029879631 scopus 로고    scopus 로고
    • Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia
    • Hara A., Iwai T., Niwa M., Uematsu T., Yoshimi N., Tanaka T. Mori H. (1996) Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia. Brain Res. 711, 249 253.
    • (1996) Brain Res. , vol.711 , pp. 249-253
    • Hara, A.1    Iwai, T.2    Niwa, M.3    Uematsu, T.4    Yoshimi, N.5    Tanaka, T.6    Mori, H.7
  • 11
    • 1842483228 scopus 로고    scopus 로고
    • The rise and fall of NMDA antagonists for ischemic stroke
    • Hoyt L., Barber P. A., Buchan A. M. Hill M. D. (2004) The rise and fall of NMDA antagonists for ischemic stroke. Curr. Mol. Med. 4, 131 136.
    • (2004) Curr. Mol. Med. , vol.4 , pp. 131-136
    • Hoyt, L.1    Barber, P.A.2    Buchan, A.M.3    Hill, M.D.4
  • 12
    • 0031020172 scopus 로고    scopus 로고
    • Bright and dark sides of nitric oxide in ischemic brain injury
    • Iadecola C. (1997) Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci. 20, 132 139.
    • (1997) Trends Neurosci. , vol.20 , pp. 132-139
    • Iadecola, C.1
  • 13
    • 0034821411 scopus 로고    scopus 로고
    • Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia
    • Imai H., Masayasu H., Dewar D., Graham D. I. Macrae I. M. (2001) Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. Stroke 32, 2149 2154.
    • (2001) Stroke , vol.32 , pp. 2149-2154
    • Imai, H.1    Masayasu, H.2    Dewar, D.3    Graham, D.I.4    MacRae, I.M.5
  • 14
    • 1042268054 scopus 로고    scopus 로고
    • Cerebral microvascular responses to hypercholesterolemia: Roles of NADPH oxidase and P-selectin
    • Ishikawa M., Stokes K. Y., Zhang J. H., Nanda A. Granger D. N. (2004) Cerebral microvascular responses to hypercholesterolemia: roles of NADPH oxidase and P-selectin. Circ. Res. 94, 239 244.
    • (2004) Circ. Res. , vol.94 , pp. 239-244
    • Ishikawa, M.1    Stokes, K.Y.2    Zhang, J.H.3    Nanda, A.4    Granger, D.N.5
  • 15
    • 0037396348 scopus 로고    scopus 로고
    • Protection against ischemic brain damage by GDNF affecting cell survival and death signals
    • Jin G., Omori N., Li F., Nagano I., Manabe Y., Shoji M. Abe K. (2003) Protection against ischemic brain damage by GDNF affecting cell survival and death signals. Neurol. Res. 25, 249 253.
    • (2003) Neurol. Res. , vol.25 , pp. 249-253
    • Jin, G.1    Omori, N.2    Li, F.3    Nagano, I.4    Manabe, Y.5    Shoji, M.6    Abe, K.7
  • 16
    • 0037373243 scopus 로고    scopus 로고
    • Production of the novel mesangial autocrine growth factors GDNF and IL-10 is regulated by the immunomodulator AS101
    • Kalechman Y., Sredni B., Weinstein T., Freidkin I., Tobar A., Albeck M. Gafter U. (2003) Production of the novel mesangial autocrine growth factors GDNF and IL-10 is regulated by the immunomodulator AS101. J. Am. Soc. Nephrol. 14, 620 630.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 620-630
    • Kalechman, Y.1    Sredni, B.2    Weinstein, T.3    Freidkin, I.4    Tobar, A.5    Albeck, M.6    Gafter, U.7
  • 17
    • 2642566996 scopus 로고    scopus 로고
    • Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis: Association with dephosphorylation of STAT3
    • Kalechman Y., Gafter U., Weinstein T., Chagnac A., Freidkin I., Tobar A., Albeck M. Sredni B. (2004) Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis: association with dephosphorylation of STAT3. J. Biol. Chem. 279, 24724 24732.
    • (2004) J. Biol. Chem. , vol.279 , pp. 24724-24732
    • Kalechman, Y.1    Gafter, U.2    Weinstein, T.3    Chagnac, A.4    Freidkin, I.5    Tobar, A.6    Albeck, M.7    Sredni, B.8
  • 18
    • 0030635616 scopus 로고    scopus 로고
    • The role of polypeptide growth factors in recovery from stroke
    • Kawamata T., Speliotes E. K. Finlestein S. P. (1997) The role of polypeptide growth factors in recovery from stroke. Adv. Neurol. 73, 377 382.
    • (1997) Adv. Neurol. , vol.73 , pp. 377-382
    • Kawamata, T.1    Speliotes, E.K.2    Finlestein, S.P.3
  • 19
    • 0030966546 scopus 로고    scopus 로고
    • Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid β-peptide: Role of the lipid peroxidation product 4-hydroxynonenal
    • Keller J. N., Pang Z., Geddes J. W., Begley J. G., Germeyer G., Waeg G. Mattson M. P. (1997) Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid β-peptide: role of the lipid peroxidation product 4-hydroxynonenal. J. Neurochem. 69, 273 284.
    • (1997) J. Neurochem. , vol.69 , pp. 273-284
    • Keller, J.N.1    Pang, Z.2    Geddes, J.W.3    Begley, J.G.4    Germeyer, G.5    Waeg, G.6    Mattson, M.P.7
  • 20
    • 17344371804 scopus 로고    scopus 로고
    • Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: Suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction
    • Keller J. N., Kindy M. S., Holtsberg F. W., St Clair D. K., Yen H. C., Germeyer A., Steiner S. M., Bruce-Keller A. J., Hutchins J. B. Mattson M. P. (1998) Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction. J. Neurosci. 18, 687 697.
    • (1998) J. Neurosci. , vol.18 , pp. 687-697
    • Keller, J.N.1    Kindy, M.S.2    Holtsberg, F.W.3    St Clair, D.K.4    Yen, H.C.5    Germeyer, A.6    Steiner, S.M.7    Bruce-Keller, A.J.8    Hutchins, J.B.9    Mattson, M.P.10
  • 21
    • 0033774103 scopus 로고    scopus 로고
    • Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury
    • Keller J. N., Huang F. F., Zhu H., Yu J., Ho Y. S. Kindy T. S. (2000) Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury. J. Cereb. Blood Flow Metab. 20, 1467 1473.
    • (2000) J. Cereb. Blood Flow Metab. , vol.20 , pp. 1467-1473
    • Keller, J.N.1    Huang, F.F.2    Zhu, H.3    Yu, J.4    Ho, Y.S.5    Kindy, T.S.6
  • 24
    • 0035167872 scopus 로고    scopus 로고
    • Oxygen radicals in cerebral ischemia: The 2001 Willis lecture
    • Kontos H. A. (2001) Oxygen radicals in cerebral ischemia: the 2001 Willis lecture. Stroke 32, 2712 2716.
    • (2001) Stroke , vol.32 , pp. 2712-2716
    • Kontos, H.A.1
  • 25
  • 26
    • 0030986669 scopus 로고    scopus 로고
    • Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis
    • Kruman I., Bruce-Keller A. J., Bredesen D., Waeg G. Mattson M. P. (1997) Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J. Neurosci. 17, 5089 5100.
    • (1997) J. Neurosci. , vol.17 , pp. 5089-5100
    • Kruman, I.1    Bruce-Keller, A.J.2    Bredesen, D.3    Waeg, G.4    Mattson, M.P.5
  • 27
    • 22544469716 scopus 로고    scopus 로고
    • Cinnamophilin reduces oxidative damage and protects against transient focal cerebral ischemia in mice
    • Lee E. J., Chen H. Y., Lee M. Y., Chen T. Y., Hsu Y. S., Hu Y. L., Chang G. L. Wu T. S. (2005) Cinnamophilin reduces oxidative damage and protects against transient focal cerebral ischemia in mice. Free Radic. Biol. Med. 39, 495 510.
    • (2005) Free Radic. Biol. Med. , vol.39 , pp. 495-510
    • Lee, E.J.1    Chen, H.Y.2    Lee, M.Y.3    Chen, T.Y.4    Hsu, Y.S.5    Hu, Y.L.6    Chang, G.L.7    Wu, T.S.8
  • 28
    • 33644946838 scopus 로고    scopus 로고
    • Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal
    • Lim J. H., Lee J. C., Lee Y. H., Choi I. Y., Oh Y. K., Kim H. S., Park J. S. Kim W. K. (2006) Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal. J. Neurochem. 97, 140 150.
    • (2006) J. Neurochem. , vol.97 , pp. 140-150
    • Lim, J.H.1    Lee, J.C.2    Lee, Y.H.3    Choi, I.Y.4    Oh, Y.K.5    Kim, H.S.6    Park, J.S.7    Kim, W.K.8
  • 29
    • 23844520894 scopus 로고    scopus 로고
    • Blockade of L-type voltage-gated Ca channel inhibits ischemia-induced neurogenesis by down-regulating iNOS expression in adult mouse
    • Luo C. X., Zhu X. J., Zhang A. X. et al. (2005) Blockade of L-type voltage-gated Ca channel inhibits ischemia-induced neurogenesis by down-regulating iNOS expression in adult mouse. J. Neurochem. 94, 1077 1086.
    • (2005) J. Neurochem. , vol.94 , pp. 1077-1086
    • Luo, C.X.1    Zhu, X.J.2    Zhang, A.X.3
  • 31
    • 0031020476 scopus 로고    scopus 로고
    • A role for 4-hydroxynonenal in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide
    • Mark R. J., Lovell M. A., Markesbery W. R., Uchida K. Mattson M. P. (1997a) A role for 4-hydroxynonenal in disruption of ion homeostasis and neuronal death induced by amyloid β-peptide. J. Neurochem. 68, 255 264.
    • (1997) J. Neurochem. , vol.68 , pp. 255-264
    • Mark, R.J.1    Lovell, M.A.2    Markesbery, W.R.3    Uchida, K.4    Mattson, M.P.5
  • 32
    • 0031020993 scopus 로고    scopus 로고
    • Amyloid β-peptide impairs glucose uptake in hippocampal and cortical neurons: Involvement of membrane lipid peroxidation
    • Mark R. J., Pang Z., Geddes J. W., Uchida K. Mattson M. P. (1997b) Amyloid β-peptide impairs glucose uptake in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. J. Neurosci. 17, 1046 1054.
    • (1997) J. Neurosci. , vol.17 , pp. 1046-1054
    • Mark, R.J.1    Pang, Z.2    Geddes, J.W.3    Uchida, K.4    Mattson, M.P.5
  • 33
    • 0032007328 scopus 로고    scopus 로고
    • Modification of ion homeostasis by lipid peroxidation: Roles in neuronal degeneration and adaptive plasticity
    • Mattson M. P. (1998) Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity. Trends Neurosci. 21, 53 57.
    • (1998) Trends Neurosci. , vol.21 , pp. 53-57
    • Mattson, M.P.1
  • 34
    • 0043180531 scopus 로고    scopus 로고
    • Excitotoxic and excitoprotective mechanisms: Abundant targets for the prevention and treatment of neurodegenerative disorders
    • Mattson M. P. (2003) Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromolecular Med. 3, 65 94.
    • (2003) Neuromolecular Med. , vol.3 , pp. 65-94
    • Mattson, M.P.1
  • 35
    • 0029175202 scopus 로고
    • Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
    • Mattson M. P., Barger S. W., Begley J. G. Mark R. J. (1995) Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol. 46, 187 216.
    • (1995) Methods Cell Biol. , vol.46 , pp. 187-216
    • Mattson, M.P.1    Barger, S.W.2    Begley, J.G.3    Mark, R.J.4
  • 36
    • 0033913058 scopus 로고    scopus 로고
    • Apoptotic and antiapoptotic mechanisms in stroke
    • Mattson M. P., Culmsee C. Yu Z. F. (2000) Apoptotic and antiapoptotic mechanisms in stroke. Cell Tissue Res. 301, 173 187.
    • (2000) Cell Tissue Res. , vol.301 , pp. 173-187
    • Mattson, M.P.1    Culmsee, C.2    Yu, Z.F.3
  • 40
    • 0030729296 scopus 로고    scopus 로고
    • Global forebrain ischemia results in differential cellular expression of interleukin-1beta (IL-1beta) and its receptor at mRNA and protein level
    • Sairanen T. R., Lindsberg P. J., Brenner M. Siren A. L. (1997) Global forebrain ischemia results in differential cellular expression of interleukin-1beta (IL-1beta) and its receptor at mRNA and protein level. J. Cereb. Blood Flow Metab. 17, 1107 1120.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 1107-1120
    • Sairanen, T.R.1    Lindsberg, P.J.2    Brenner, M.3    Siren, A.L.4
  • 41
    • 0030951213 scopus 로고    scopus 로고
    • Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats
    • Schabitz W. R., Schwab S., Spranger M. Hacke W. (1997) Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 17, 500 506.
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 500-506
    • Schabitz, W.R.1    Schwab, S.2    Spranger, M.3    Hacke, W.4
  • 42
    • 27144437262 scopus 로고    scopus 로고
    • T-cell cytokines in injury-induced neural damage and repair
    • Schroeter M. Jander S. (2005) T-cell cytokines in injury-induced neural damage and repair. Neuromolecular Med. 7, 183 195.
    • (2005) Neuromolecular Med. , vol.7 , pp. 183-195
    • Schroeter, M.1    Jander, S.2
  • 43
    • 0036854699 scopus 로고    scopus 로고
    • Neuroprotective effects of NS-7, voltage-gated Na+/Ca2+ channel blocker in a rodent model of transient focal ischaemia
    • Sopala M., Danysz W. Quack G. (2002) Neuroprotective effects of NS-7, voltage-gated Na+/Ca2+ channel blocker in a rodent model of transient focal ischaemia. Neurotox. Res. 4, 655 661.
    • (2002) Neurotox. Res. , vol.4 , pp. 655-661
    • Sopala, M.1    Danysz, W.2    Quack, G.3
  • 45
    • 0030070066 scopus 로고    scopus 로고
    • The protective role of the immunomodulator AS101 against chemotherapy-induced alopecia studies on human and animal models
    • Sredni B., Xu R. H., Albeck M. et al. (1996) The protective role of the immunomodulator AS101 against chemotherapy-induced alopecia studies on human and animal models. Int. J. Cancer 65, 97 103.
    • (1996) Int. J. Cancer , vol.65 , pp. 97-103
    • Sredni, B.1    Xu, R.H.2    Albeck, M.3
  • 46
    • 1442339222 scopus 로고    scopus 로고
    • Hair growth induction by the tellurium immunomodulator AS101: Association with delayed terminal differentiation of follicular keratinocytes and ras-dependent up-regulation of KGF expression
    • Sredni B., Gal R., Cohen I. J. et al. (2004) Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras-dependent up-regulation of KGF expression. FASEB J. 18, 400 402.
    • (2004) FASEB J. , vol.18 , pp. 400-402
    • Sredni, B.1    Gal, R.2    Cohen, I.J.3
  • 47
    • 34249823664 scopus 로고    scopus 로고
    • Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models
    • E-pub ahead of print.
    • Sredni B., Geffen R., Kalechman Y. et al. (2007) Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models. FASEB J. E-pub ahead of print.
    • (2007) FASEB J.
    • Sredni, B.1    Geffen, R.2    Kalechman, Y.3
  • 48
    • 0036069281 scopus 로고    scopus 로고
    • Peroxynitrite affects exocytosis and SNARE complex formation and induces tyrosine nitration of synaptic proteins
    • Stasi A. M., Mallozzi C., Macchia G., Maura G., Petrucci T. C. Minetti M. (2002) Peroxynitrite affects exocytosis and SNARE complex formation and induces tyrosine nitration of synaptic proteins. J. Neurochem. 82, 420 429.
    • (2002) J. Neurochem. , vol.82 , pp. 420-429
    • Stasi, A.M.1    Mallozzi, C.2    MacChia, G.3    Maura, G.4    Petrucci, T.C.5    Minetti, M.6
  • 49
    • 0142139346 scopus 로고    scopus 로고
    • Reactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemia
    • Sugawara T. Chan P. H. (2003) Reactive oxygen radicals and pathogenesis of neuronal death after cerebral ischemia. Antioxid. Redox Signal 5, 97 607.
    • (2003) Antioxid. Redox Signal , vol.5 , pp. 97-607
    • Sugawara, T.1    Chan, P.H.2
  • 50
    • 0036138386 scopus 로고    scopus 로고
    • Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation
    • Sugawara T., Noshita N., Lewen A., Gasche Y., Ferrand-Drake M., Fujimura M., Morita-Fujimura Y. Chan P. H. (2002) Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation. J. Neurosci. 22, 209 217.
    • (2002) J. Neurosci. , vol.22 , pp. 209-217
    • Sugawara, T.1    Noshita, N.2    Lewen, A.3    Gasche, Y.4    Ferrand-Drake, M.5    Fujimura, M.6    Morita-Fujimura, Y.7    Chan, P.H.8
  • 51
    • 0037072647 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in the ischemic core and penumbra after transient focal cerebral ischemia in mice
    • Zhu D. Y., Deng Q., Yao H. H., Wang D. C., Deng Y. Liu G. Q. (2002) Inducible nitric oxide synthase expression in the ischemic core and penumbra after transient focal cerebral ischemia in mice. Life Sci. 71, 1985 1996.
    • (2002) Life Sci. , vol.71 , pp. 1985-1996
    • Zhu, D.Y.1    Deng, Q.2    Yao, H.H.3    Wang, D.C.4    Deng, Y.5    Liu, G.Q.6
  • 52
    • 0025947863 scopus 로고
    • Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons
    • del Zoppo G. J., Schmid-Schonbein G. W., Mori E., Copeland B. R. Chang C. M. (1991) Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 22, 1276 1283.
    • (1991) Stroke , vol.22 , pp. 1276-1283
    • Del Zoppo, G.J.1    Schmid-Schonbein, G.W.2    Mori, E.3    Copeland, B.R.4    Chang, C.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.