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Volumn 6, Issue , 2015, Pages

Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; DNA DEPENDENT PROTEIN KINASE; GLYCOPROTEIN P 15095; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MACROPHAGE DERIVED CHEMOKINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RANTES; REACTIVE OXYGEN METABOLITE; 8-DIBENZOTHIOPHEN-4-YL-2-MORPHOLIN-4-YL-CHROMEN-4-ONE; CHROMONE DERIVATIVE; DNA BINDING PROTEIN; IMMUNOGLOBULIN E; MORPHOLINE DERIVATIVE; NUCLEAR PROTEIN; PRKDC PROTEIN, MOUSE;

EID: 84923658913     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7224     Document Type: Article
Times cited : (35)

References (64)
  • 1
    • 84881498136 scopus 로고    scopus 로고
    • Small molecules, inhibitors of DNA-PK, targeting DNA repair, and beyond
    • Davidson, D., Amrein, L., Panasci, L. & Aloyz, R. Small molecules, inhibitors of DNA-PK, targeting DNA repair, and beyond. Front. Pharmacol. 4, 5 (2013).
    • (2013) Front. Pharmacol. , vol.4 , pp. 5
    • Davidson, D.1    Amrein, L.2    Panasci, L.3    Aloyz, R.4
  • 2
    • 79955803751 scopus 로고    scopus 로고
    • Emerging roles of DNA-PK besides DNA repair
    • Kong, X., Shen, Y., Jiang, N., Fei, X. & Mi, J. Emerging roles of DNA-PK besides DNA repair. Cell. Signal. 23, 1273-1280 (2011).
    • (2011) Cell. Signal. , vol.23 , pp. 1273-1280
    • Kong, X.1    Shen, Y.2    Jiang, N.3    Fei, X.4    Mi, J.5
  • 3
    • 57949116437 scopus 로고    scopus 로고
    • DNA-PK: The means to justify the ends?
    • Meek, K., Dang, V. & Lees-Miller, S. P. DNA-PK: the means to justify the ends? Adv. Immunol. 99, 33-58 (2008).
    • (2008) Adv. Immunol. , vol.99 , pp. 33-58
    • Meek, K.1    Dang, V.2    Lees-Miller, S.P.3
  • 4
    • 84867478618 scopus 로고    scopus 로고
    • New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress
    • Chen, B. P., Li, M. & Asaithamby, A. New insights into the roles of ATM and DNA-PKcs in the cellular response to oxidative stress. Cancer Lett. 327, 103-110 (2012).
    • (2012) Cancer Lett. , vol.327 , pp. 103-110
    • Chen, B.P.1    Li, M.2    Asaithamby, A.3
  • 5
    • 79956220705 scopus 로고    scopus 로고
    • Choosing the right path: Does DNA-PK help make the decision?
    • Neal, J. A. & Meek, K. Choosing the right path: does DNA-PK help make the decision? Mutat. Res. 711, 73-86 (2011).
    • (2011) Mutat. Res. , vol.711 , pp. 73-86
    • Neal, J.A.1    Meek, K.2
  • 6
    • 0037155703 scopus 로고    scopus 로고
    • Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D) J recombination
    • Ma, Y., Pannicke, U., Schwarz, K. & Lieber, M. R. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell 108, 781-794 (2002).
    • (2002) Cell , vol.108 , pp. 781-794
    • Ma, Y.1    Pannicke, U.2    Schwarz, K.3    Lieber, M.R.4
  • 7
    • 0028960511 scopus 로고
    • Defective DNA-dependent protein kinase activity is linked to V(D) J recombination and DNA repair defects associated with the murine scid mutation
    • Blunt, T. et al. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 80, 813-823 (1995).
    • (1995) Cell , vol.80 , pp. 813-823
    • Blunt, T.1
  • 8
    • 0020663062 scopus 로고
    • A severe combined immunodeficiency mutation in the mouse
    • Bosma, G. C., Custer, R. P. & Bosma, M. J. A severe combined immunodeficiency mutation in the mouse. Nature 301, 527-530 (1983).
    • (1983) Nature , vol.301 , pp. 527-530
    • Bosma, G.C.1    Custer, R.P.2    Bosma, M.J.3
  • 9
    • 0021321097 scopus 로고
    • Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease
    • Dorshkind, K. et al. Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease. J. Immunol. 132, 1804-1808 (1984).
    • (1984) J. Immunol. , vol.132 , pp. 1804-1808
    • Dorshkind, K.1
  • 11
    • 0029788520 scopus 로고    scopus 로고
    • Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse
    • Blunt, T. et al. Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse. Proc. Natl Acad. Sci. USA 93, 10285-10290 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 10285-10290
    • Blunt, T.1
  • 12
    • 0029791450 scopus 로고    scopus 로고
    • Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes
    • Danska, J. S., Holland, D. P., Mariathasan, S., Williams, K. M. & Guidos, C. J. Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes. Mol. Cell Biol. 16, 5507-5517 (1996).
    • (1996) Mol. Cell Biol. , vol.16 , pp. 5507-5517
    • Danska, J.S.1    Holland, D.P.2    Mariathasan, S.3    Williams, K.M.4    Guidos, C.J.5
  • 13
    • 0032167545 scopus 로고    scopus 로고
    • Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity
    • Taccioli, G. E. et al. Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity. Immunity 9, 355-366 (1998).
    • (1998) Immunity , vol.9 , pp. 355-366
    • Taccioli, G.E.1
  • 14
    • 84875224757 scopus 로고    scopus 로고
    • DNA-PK is a DNA sensor for IRF-3-dependent innate immunity
    • Ferguson, B. J., Mansur, D. S., Peters, N. E., Ren, H. & Smith, G. L. DNA-PK is a DNA sensor for IRF-3-dependent innate immunity. Elife 1, e00047 (2012).
    • (2012) Elife , vol.1 , pp. e00047
    • Ferguson, B.J.1    Mansur, D.S.2    Peters, N.E.3    Ren, H.4    Smith, G.L.5
  • 15
    • 84885631238 scopus 로고    scopus 로고
    • A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus
    • Peters, N. E. et al. A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus. PLoS Pathog. 9, e1003649 (2013).
    • (2013) PLoS Pathog. , vol.9 , pp. e1003649
    • Peters, N.E.1
  • 16
    • 84879422443 scopus 로고    scopus 로고
    • HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration
    • Cooper, A. et al. HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration. Nature 498, 376-379 (2013).
    • (2013) Nature , vol.498 , pp. 376-379
    • Cooper, A.1
  • 17
    • 84897994129 scopus 로고    scopus 로고
    • Listeria monocytogenes induces host DNA damage and delays the host cell cycle to promote infection
    • Leitao, E. et al. Listeria monocytogenes induces host DNA damage and delays the host cell cycle to promote infection. Cell Cycle 13, 928-940 (2014).
    • (2014) Cell Cycle , vol.13 , pp. 928-940
    • Leitao, E.1
  • 18
    • 77952572147 scopus 로고    scopus 로고
    • DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells
    • Rajagopalan, S., Moyle, M. W., Joosten, I. & Long, E. O. DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells. Sci. Signal. 3, ra14 (2010).
    • (2010) Sci. Signal. , vol.3 , pp. ra14
    • Rajagopalan, S.1    Moyle, M.W.2    Joosten, I.3    Long, E.O.4
  • 19
    • 78650332591 scopus 로고    scopus 로고
    • Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment
    • Ju, J. et al. Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment. J. Biol. Chem. 285, 41152-41160 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 41152-41160
    • Ju, J.1
  • 20
    • 84891830448 scopus 로고    scopus 로고
    • Inhibition of DNA-dependent protein kinase reduced palmitate and oleate-induced lipid accumulation in HepG2 cells
    • Kwan, H. Y., Fong, W. F., Yang, Z., Yu, Z. L. & Hsiao, W. L. Inhibition of DNA-dependent protein kinase reduced palmitate and oleate-induced lipid accumulation in HepG2 cells. Eur. J. Nutr. 52, 1621-1630 (2013).
    • (2013) Eur. J. Nutr. , vol.52 , pp. 1621-1630
    • Kwan, H.Y.1    Fong, W.F.2    Yang, Z.3    Yu, Z.L.4    Hsiao, W.L.5
  • 21
    • 79251549181 scopus 로고    scopus 로고
    • Induces shedding of the 34-kDa soluble TNFR1 from human airway epithelial cells via TLR3-TRIF-RIP1-dependent signaling: Roles for dual oxidase 2-and caspase-dependent pathways
    • Yu, M. et al. induces shedding of the 34-kDa soluble TNFR1 from human airway epithelial cells via TLR3-TRIF-RIP1-dependent signaling: roles for dual oxidase 2-and caspase-dependent pathways. J. Immunol. 186, 1180-1188 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 1180-1188
    • Yu, M.1
  • 22
    • 17644384427 scopus 로고    scopus 로고
    • Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks
    • Chen, B. P. et al. Cell cycle dependence of DNA-dependent protein kinase phosphorylation in response to DNA double strand breaks. J. Biol. Chem. 280, 14709-14715 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 14709-14715
    • Chen, B.P.1
  • 23
    • 3843104695 scopus 로고    scopus 로고
    • Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity
    • Bhattacharyya, S. et al. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity. Blood 104, 1100-1109 (2004).
    • (2004) Blood , vol.104 , pp. 1100-1109
    • Bhattacharyya, S.1
  • 24
    • 0025697469 scopus 로고
    • Induction by antigen of intrathymic apoptosis of CD4\+CD8\+TCRlo thymocytes in vivo
    • Murphy, K. M., Heimberger, A. B. & Loh, D. Y. Induction by antigen of intrathymic apoptosis of CD4\+CD8\+TCRlo thymocytes in vivo. Science 250, 1720-1723 (1990).
    • (1990) Science , vol.250 , pp. 1720-1723
    • Murphy, K.M.1    Heimberger, A.B.2    Loh, D.Y.3
  • 25
    • 55849148482 scopus 로고    scopus 로고
    • The cytokine network in asthma and chronic obstructive pulmonary disease
    • Barnes, P. J. The cytokine network in asthma and chronic obstructive pulmonary disease. J. Clin. Invest. 118, 3546-3556 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 3546-3556
    • Barnes, P.J.1
  • 26
    • 0035865355 scopus 로고    scopus 로고
    • Expression of chemokine receptors by lung T cells from normal and asthmatic subjects
    • Campbell, J. J. et al. Expression of chemokine receptors by lung T cells from normal and asthmatic subjects. J. Immunol. 166, 2842-2848 (2001).
    • (2001) J. Immunol. , vol.166 , pp. 2842-2848
    • Campbell, J.J.1
  • 27
    • 53549118024 scopus 로고    scopus 로고
    • The catalytic subunit of DNAdependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells
    • Ruis, B. L., Fattah, K. R. & Hendrickson, E. A. The catalytic subunit of DNAdependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells. Mol. Cell Biol. 28, 6182-6195 (2008).
    • (2008) Mol. Cell Biol. , vol.28 , pp. 6182-6195
    • Ruis, B.L.1    Fattah, K.R.2    Hendrickson, E.A.3
  • 28
    • 84871803451 scopus 로고    scopus 로고
    • Resident CD11b(\+)Ly6C(-) lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice
    • Mesnil, C. et al. Resident CD11b(\+)Ly6C(-) lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. PLoS ONE 7, e53242 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e53242
    • Mesnil, C.1
  • 29
    • 84874254531 scopus 로고    scopus 로고
    • Conventional and monocyte-derived CD11b(\+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen
    • Plantinga, M. et al. Conventional and monocyte-derived CD11b(\+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. Immunity 38, 322-335 (2013).
    • (2013) Immunity , vol.38 , pp. 322-335
    • Plantinga, M.1
  • 30
    • 84892815323 scopus 로고    scopus 로고
    • Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation
    • Vander Lugt, B. et al. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat. Immunol. 15, 161-167 (2014).
    • (2014) Nat. Immunol. , vol.15 , pp. 161-167
    • Vander Lugt, B.1
  • 31
    • 84859384234 scopus 로고    scopus 로고
    • DNA-PKcs interacts with Aire and regulates the expression of tolllike receptors in RAW2647 cells
    • Wu, J. et al. DNA-PKcs interacts with Aire and regulates the expression of tolllike receptors in RAW264.7 cells. Scand. J. Immunol. 75, 479-488 (2012).
    • (2012) Scand. J. Immunol. , vol.75 , pp. 479-488
    • Wu, J.1
  • 32
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • Hammad, H. et al. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat. Med. 15, 410-416 (2009).
    • (2009) Nat. Med. , vol.15 , pp. 410-416
    • Hammad, H.1
  • 33
    • 84869209695 scopus 로고    scopus 로고
    • The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens
    • Wilson, R. H. et al. The Toll-like receptor 5 ligand flagellin promotes asthma by priming allergic responses to indoor allergens. Nat. Med. 18, 1705-1710 (2012).
    • (2012) Nat. Med. , vol.18 , pp. 1705-1710
    • Wilson, R.H.1
  • 34
    • 84859404292 scopus 로고    scopus 로고
    • Lung dendritic cells in respiratory viral infection and asthma: From protection to immunopathology
    • Lambrecht, B. N. & Hammad, H. Lung dendritic cells in respiratory viral infection and asthma: from protection to immunopathology. Annu. Rev. Immunol. 30, 243-270 (2012).
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 243-270
    • Lambrecht, B.N.1    Hammad, H.2
  • 35
    • 77957745031 scopus 로고    scopus 로고
    • Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
    • Hammad, H. et al. Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J. Exp. Med. 207, 2097-2111 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 2097-2111
    • Hammad, H.1
  • 36
    • 0037443644 scopus 로고    scopus 로고
    • The roles of Toll-like receptor 9 MyD88 and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets
    • Hemmi, H., Kaisho, T., Takeda, K. & Akira, S. The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J. Immunol. 170, 3059-3064 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 3059-3064
    • Hemmi, H.1    Kaisho, T.2    Takeda, K.3    Akira, S.4
  • 37
    • 0037099629 scopus 로고    scopus 로고
    • Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation
    • Ishii, K. J. et al. Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation. J. Exp. Med. 196, 269-274 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 269-274
    • Ishii, K.J.1
  • 38
    • 84875323016 scopus 로고    scopus 로고
    • Involvement of DNA-PKcs in the IL-6 and IL-12 response to CpG-ODN is mediated by its interaction with TRAF6 in dendritic cells
    • Ma, C., Muranyi, M., Chu, C. H., Zhang, J. & Chu, W. M. Involvement of DNA-PKcs in the IL-6 and IL-12 response to CpG-ODN is mediated by its interaction with TRAF6 in dendritic cells. PLoS ONE 8, e58072 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e58072
    • Ma, C.1    Muranyi, M.2    Chu, C.H.3    Zhang, J.4    Chu, W.M.5
  • 39
    • 79958109315 scopus 로고    scopus 로고
    • A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia
    • Bouquet, F. et al. A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia. J. Cell Sci. 124, 1943-1951 (2011).
    • (2011) J. Cell Sci. , vol.124 , pp. 1943-1951
    • Bouquet, F.1
  • 40
    • 84876792708 scopus 로고    scopus 로고
    • The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in the selenium-induced senescence response
    • Rocourt, C. R., Wu, M., Chen, B. P. & Cheng, W. H. The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in the selenium-induced senescence response. J. Nutr. Biochem. 24, 781-787 (2013).
    • (2013) J. Nutr. Biochem. , vol.24 , pp. 781-787
    • Rocourt, C.R.1    Wu, M.2    Chen, B.P.3    Cheng, W.H.4
  • 41
    • 67349133769 scopus 로고    scopus 로고
    • Artemis is a negative regulator of p53 in response to oxidative stress
    • Zhang, X., Zhu, Y., Geng, L., Wang, H. & Legerski, R. J. Artemis is a negative regulator of p53 in response to oxidative stress. Oncogene 28, 2196-2204 (2009).
    • (2009) Oncogene , vol.28 , pp. 2196-2204
    • Zhang, X.1    Zhu, Y.2    Geng, L.3    Wang, H.4    Legerski, R.J.5
  • 42
    • 4644359805 scopus 로고    scopus 로고
    • Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase
    • Feng, J., Park, J., Cron, P., Hess, D. & Hemmings, B. A. Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase. J. Biol. Chem. 279, 41189-41196 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 41189-41196
    • Feng, J.1    Park, J.2    Cron, P.3    Hess, D.4    Hemmings, B.A.5
  • 43
    • 42949165854 scopus 로고    scopus 로고
    • PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival
    • Bozulic, L., Surucu, B., Hynx, D. & Hemmings, B. A. PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival. Mol. Cell 30, 203-213 (2008).
    • (2008) Mol. Cell , vol.30 , pp. 203-213
    • Bozulic, L.1    Surucu, B.2    Hynx, D.3    Hemmings, B.A.4
  • 44
    • 0042834309 scopus 로고    scopus 로고
    • Generation and function of reactive oxygen species in dendritic cells during antigen presentation
    • Matsue, H. et al. Generation and function of reactive oxygen species in dendritic cells during antigen presentation. J. Immunol. 171, 3010-3018 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 3010-3018
    • Matsue, H.1
  • 45
    • 22944444543 scopus 로고    scopus 로고
    • Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells
    • Maemura, K. et al. Reactive oxygen species are essential mediators in antigen presentation by Kupffer cells. Immunol. Cell Biol. 83, 336-343 (2005).
    • (2005) Immunol. Cell Biol. , vol.83 , pp. 336-343
    • Maemura, K.1
  • 46
    • 84872474723 scopus 로고    scopus 로고
    • Reactive oxygen species production in the phagosome: Impact on antigen presentation in dendritic cells
    • Kotsias, F., Hoffmann, E., Amigorena, S. & Savina, A. Reactive oxygen species production in the phagosome: impact on antigen presentation in dendritic cells. Antioxid. Redox. Signal. 18, 714-729 (2013).
    • (2013) Antioxid. Redox. Signal. , vol.18 , pp. 714-729
    • Kotsias, F.1    Hoffmann, E.2    Amigorena, S.3    Savina, A.4
  • 47
    • 84883483307 scopus 로고    scopus 로고
    • Deficiency of gp91phox inhibits allergic airway inflammation
    • Sevin, C. M. et al. Deficiency of gp91phox inhibits allergic airway inflammation. Am. J. Respir. Cell Mol. Biol. 49, 396-402 (2013).
    • (2013) Am. J. Respir. Cell Mol. Biol. , vol.49 , pp. 396-402
    • Sevin, C.M.1
  • 48
    • 77953812779 scopus 로고    scopus 로고
    • The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling
    • Tang, H. et al. The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat. Immunol. 11, 608-617 (2010).
    • (2010) Nat. Immunol. , vol.11 , pp. 608-617
    • Tang, H.1
  • 49
    • 33745712871 scopus 로고    scopus 로고
    • Dendritic cells in a mature age
    • Reis e Sousa, C. Dendritic cells in a mature age. Nat. Rev. Immunol. 6, 476-483 (2006).
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 476-483
    • Reis, E.1    Sousa, C.2
  • 50
    • 17144405680 scopus 로고    scopus 로고
    • Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
    • Hawrylowicz, C. M. & O'Garra, A. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat. Rev. Immunol. 5, 271-283 (2005).
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 271-283
    • Hawrylowicz, C.M.1    O'Garra, A.2
  • 51
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva, M. & O'Garra, A. The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 10, 170-181 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 52
    • 77952377269 scopus 로고    scopus 로고
    • Negative regulation of MyD88-dependent signaling by IL-10 in dendritic cells
    • Chang, J., Kunkel, S. L. & Chang, C. H. Negative regulation of MyD88-dependent signaling by IL-10 in dendritic cells. Proc. Natl Acad. Sci. USA 106, 18327-18332 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 18327-18332
    • Chang, J.1    Kunkel, S.L.2    Chang, C.H.3
  • 53
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
    • Akbari, O., DeKruyff, R. H. & Umetsu, D. T. Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2, 725-731 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 725-731
    • Akbari, O.1    Dekruyff, R.H.2    Umetsu, D.T.3
  • 54
    • 18944384312 scopus 로고    scopus 로고
    • Vivo IL-10 gene delivery suppresses airway eosinophilia and hyperreactivity by down-regulating APC functions and migration without impairing the antigen-specific systemic immune response in a mouse model of allergic airway inflammation
    • Nakagome, K. et al. In vivo IL-10 gene delivery suppresses airway eosinophilia and hyperreactivity by down-regulating APC functions and migration without impairing the antigen-specific systemic immune response in a mouse model of allergic airway inflammation. J. Immunol. 174, 6955-6966 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 6955-6966
    • Nakagome, K.1
  • 55
    • 0037237593 scopus 로고    scopus 로고
    • Mycobacteria target DC-SIGN to suppress dendritic cell function
    • Geijtenbeek, T. B. et al. Mycobacteria target DC-SIGN to suppress dendritic cell function. J. Exp. Med. 197, 7-17 (2003).
    • (2003) J. Exp. Med. , vol.197 , pp. 7-17
    • Geijtenbeek, T.B.1
  • 56
    • 8844254050 scopus 로고    scopus 로고
    • Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries
    • Leahy, J. J. et al. Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries. Bioorg. Med. Chem. Lett. 14, 6083-6087 (2004).
    • (2004) Bioorg. Med. Chem. Lett. , vol.14 , pp. 6083-6087
    • Leahy, J.J.1
  • 57
    • 33744924482 scopus 로고    scopus 로고
    • Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441
    • Zhao, Y. et al. Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441. Cancer Res. 66, 5354-5362 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 5354-5362
    • Zhao, Y.1
  • 58
    • 0024210186 scopus 로고
    • Adoptive immunity in immune-deficient scid/scid mice I. Differential requirements of naive and primed lymphocytes for CD4\+ T cells during rejection of minor histocompatibility antigendisparate skin grafts
    • Roopenian, D. C. & Anderson, P. S. Adoptive immunity in immune-deficient scid/scid mice. I. Differential requirements of naive and primed lymphocytes for CD4\+ T cells during rejection of minor histocompatibility antigendisparate skin grafts. Transplantation 46, 899-904 (1988).
    • (1988) Transplantation , vol.46 , pp. 899-904
    • Roopenian, D.C.1    Anderson, P.S.2
  • 59
    • 0026739818 scopus 로고
    • Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4\+ but not CD8\+ T cells into severe combined immunodeficiency mice
    • Roths, J. B. & Sidman, C. L. Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4\+ but not CD8\+ T cells into severe combined immunodeficiency mice. J. Clin. Invest. 90, 673-678 (1992).
    • (1992) J. Clin. Invest. , vol.90 , pp. 673-678
    • Roths, J.B.1    Sidman, C.L.2
  • 60
    • 0037262719 scopus 로고    scopus 로고
    • A new model of chronic colitis in SCID mice induced by adoptive transfer of CD62L\+ CD4\+ T cells: Insights into the regulatory role of interleukin-6 on apoptosis
    • Mudter, J., Wirtz, S., Galle, P. R. & Neurath, M. F. A new model of chronic colitis in SCID mice induced by adoptive transfer of CD62L\+ CD4\+ T cells: insights into the regulatory role of interleukin-6 on apoptosis. Pathobiology 70, 170-176 (2002).
    • (2002) Pathobiology , vol.70 , pp. 170-176
    • Mudter, J.1    Wirtz, S.2    Galle, P.R.3    Neurath, M.F.4
  • 61
    • 0037352031 scopus 로고    scopus 로고
    • A highly efficient recombineeringbased method for generating conditional knockout mutations
    • Liu, P., Jenkins, N. A. & Copeland, N. G. A highly efficient recombineeringbased method for generating conditional knockout mutations. Genome Res. 13, 476-484 (2003).
    • (2003) Genome Res. , vol.13 , pp. 476-484
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 62
    • 0035933198 scopus 로고    scopus 로고
    • Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation
    • Eggan, K. et al. Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation. Proc. Natl Acad. Sci. USA 98, 6209-6214 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 6209-6214
    • Eggan, K.1
  • 63
    • 0029803775 scopus 로고    scopus 로고
    • Generation of CD1\+RelB\+ dendritic cells and tartrateresistant acid phosphatase-positive osteoclast-like multinucleated giant cells from human monocytes
    • Akagawa, K. S. et al. Generation of CD1\+RelB\+ dendritic cells and tartrateresistant acid phosphatase-positive osteoclast-like multinucleated giant cells from human monocytes. Blood 88, 4029-4039 (1996).
    • (1996) Blood , vol.88 , pp. 4029-4039
    • Akagawa, K.S.1
  • 64
    • 84872683119 scopus 로고    scopus 로고
    • And rapid isolation and purification of mouse alveolar type II epithelial cells
    • Messier, E. M., Mason, R. J. & Kosmider, B. Efficient and rapid isolation and purification of mouse alveolar type II epithelial cells. Exp. Lung Res. 38, 363-373 (2012).
    • (2012) Exp. Lung Res. , vol.38 , pp. 363-373
    • Messier, E.M.1    Mason, R.J.2    Efficient, K.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.