-
1
-
-
84877819591
-
Advances in CTLA-4-Ig-mediated modulation of inflammatory cell and immune response activation in rheumatoid arthritis
-
Cutolo, M. &Nadler, S. G. Advances in CTLA-4-Ig-mediated modulation of inflammatory cell and immune response activation in rheumatoid arthritis. Autoimmun Rev. 12, 758-767 (2013)
-
(2013)
Autoimmun Rev
, vol.12
, pp. 758-767
-
-
Cutolo, M.1
Nadler, S.G.2
-
2
-
-
33845414970
-
Abatacept in the treatment of rheumatoid arthritis
-
Vital, E. M. &Emery, P. Abatacept in the treatment of rheumatoid arthritis. Ther Clin Risk Manag. 2, 365-375 (2006)
-
(2006)
Ther Clin Risk Manag
, vol.2
, pp. 365-375
-
-
Vital, E.M.1
Emery, P.2
-
3
-
-
84873396202
-
Targeting the B7 family of co-stimulatory molecules: Successes and challenges
-
Podojil, J. R. &Miller, S. D. Targeting the B7 family of co-stimulatory molecules: successes and challenges. BioDrugs. 27, 1-13 (2013)
-
(2013)
BioDrugs
, vol.27
, pp. 1-13
-
-
Podojil, J.R.1
Miller, S.D.2
-
4
-
-
0033029507
-
The role of CTLA-4 in the regulation of T cell immune responses
-
McCoy, K. D.&LeGros, G. The role of CTLA-4 in the regulation of T cell immune responses. Immunol Cell Biol. 77, 1-10 (1999)
-
(1999)
Immunol Cell Biol
, vol.77
, pp. 1-10
-
-
McCoy, K.D.1
Legros, G.2
-
5
-
-
0025830902
-
CTLA-4 is a second receptor for the B cell activation antigen B7
-
Linsley, P. S. et al. CTLA-4 is a second receptor for the B cell activation antigen B7. J. Exp Med. 174, 561-569 (1991)
-
(1991)
J. Exp Med
, vol.174
, pp. 561-569
-
-
Linsley, P.S.1
-
6
-
-
33745860066
-
CTLA-4 overexpression inhibits T cell responses through a CD28-B7-dependent mechanism
-
Engelhardt, J. J., Sullivan, T. J. &Allison, J. P. CTLA-4 overexpression inhibits T cell responses through a CD28-B7-dependent mechanism. J. Immunol. 177, 1052-1061 (2006)
-
(2006)
J. Immunol
, vol.177
, pp. 1052-1061
-
-
Engelhardt, J.J.1
Sullivan, T.J.2
Allison, J.P.3
-
7
-
-
80053493531
-
Subcutaneous abatacept versus intravenous abatacept: A phase IIIb noninferiority study in patients with an inadequate response to methotrexate
-
Genovese, M. C. et al. Subcutaneous abatacept versus intravenous abatacept: a phase IIIb noninferiority study in patients with an inadequate response to methotrexate. Arthritis Rheum. 63, 2854-2864 (2011)
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2854-2864
-
-
Genovese, M.C.1
-
8
-
-
84887310979
-
Administration costs of intravenous biologic drugs for rheumatoid arthritis
-
Soini, E. J., Leussu, M. &Hallinen, T. Administration costs of intravenous biologic drugs for rheumatoid arthritis. Springerplus. 2, 531 (2013)
-
(2013)
Springerplus
, vol.2
, pp. 531
-
-
Soini, E.J.1
Leussu, M.2
Hallinen, T.3
-
9
-
-
0041315884
-
MinicircleDNAvectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
-
Chen, Z. Y., He, C. Y., Ehrhardt, A.&Kay,M.A.MinicircleDNAvectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Mol Ther. 8, 495-500 (2003)
-
(2003)
Mol Ther
, vol.8
, pp. 495-500
-
-
Chen, Z.Y.1
He, Y.C.2
Ehrhardt, A.3
Kay, M.A.4
-
10
-
-
84871919467
-
Minicircle DNA vectors achieve sustained expression reflected by active chromatin and transcriptional level
-
Gracey Maniar, L. E. et al. Minicircle DNA vectors achieve sustained expression reflected by active chromatin and transcriptional level. Mol Ther. 21, 131-138 (2013)
-
(2013)
Mol Ther
, vol.21
, pp. 131-138
-
-
Gracey Maniar, L.E.1
-
11
-
-
78650028269
-
A robust system for production of minicircle DNA vectors
-
Kay, M. A., He, C. Y. &Chen, Z. Y. A robust system for production of minicircle DNA vectors. Nat Biotechnol. 28, 1287-1289
-
Nat Biotechnol
, vol.28
, pp. 1287-1289
-
-
Kay, M.A.1
He, C.Y.2
Chen, Z.Y.3
-
12
-
-
60449098993
-
Progress and prospects: The design and production of plasmid vectors
-
Gill, D. R., Pringle, I. A. &Hyde, S. C. Progress and prospects: the design and production of plasmid vectors. Gene Ther. 16, 165-171 (2009)
-
(2009)
Gene Ther
, vol.16
, pp. 165-171
-
-
Gill, D.R.1
Pringle, I.A.2
Hyde, S.C.3
-
13
-
-
70349786604
-
Novel minicircle vector for gene therapy in murine myocardial infarction
-
Huang, M. et al. Novel minicircle vector for gene therapy in murine myocardial infarction. Circulation. 120, S230-237 (2009)
-
(2009)
Circulation
, vol.120
, pp. S230-237
-
-
Huang, M.1
-
14
-
-
33746265976
-
Mechanism of plasmid delivery by hydrodynamic tail vein injection i Hepatocyte uptake of various molecules
-
Sebestyen, M. G. et al. Mechanism of plasmid delivery by hydrodynamic tail vein injection. I. Hepatocyte uptake of various molecules. J. Gene Med. 8, 852-873 (2006)
-
(2006)
J. Gene Med
, vol.8
, pp. 852-873
-
-
Sebestyen, M.G.1
-
15
-
-
4644241242
-
Hydrodynamics-based transfection of the liver: Entrance into hepatocytes ofDNA that causes expression takes place very early after injection
-
Andrianaivo, F., Lecocq, M., Wattiaux-De Coninck, S., Wattiaux, R. &Jadot, M. Hydrodynamics-based transfection of the liver: entrance into hepatocytes ofDNA that causes expression takes place very early after injection. J. Gene Med. 6, 877-883 (2004)
-
(2004)
J. Gene Med
, vol.6
, pp. 877-883
-
-
Andrianaivo, F.1
Lecocq, M.2
Wattiaux-De Coninck, S.3
Wattiaux, R.4
Jadot, M.5
-
16
-
-
0034152996
-
Hypo thesis naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process
-
Budker, V. et al. Hypothesis: naked plasmid DNA is taken up by cells in vivo by a receptor-mediated process. J. Gene Med. 2, 76-88 (2000)
-
(2000)
J. Gene Med
, vol.2
, pp. 76-88
-
-
Budker, V.1
-
17
-
-
1642555021
-
Hydrodynamics-based procedure involves transient hyperpermeability in the hepatic cellularmembrane: Implication of a nonspecific process in efficient intracellular gene delivery
-
Kobayashi, N., Nishikawa, M., Hirata, K. &Takakura, Y. Hydrodynamics-based procedure involves transient hyperpermeability in the hepatic cellularmembrane: implication of a nonspecific process in efficient intracellular gene delivery. J. Gene Med. 6, 584-592 (2004)
-
(2004)
J. Gene Med
, vol.6
, pp. 584-592
-
-
Kobayashi, N.1
Nishikawa, M.2
Hirata, K.3
Takakura, Y.4
-
18
-
-
41149091775
-
CTLA-4 x Ig converts naive CD41CD25-T cells into CD41CD251regulatory T cells
-
Razmara, M., Hilliard, B., Ziarani, A. K., Chen, Y. H. &Tykocinski, M. L. CTLA-4 x Ig converts naive CD41CD25-T cells into CD41CD251regulatory T cells. Int. Immunol. 20, 471-483 (2008)
-
(2008)
Int. Immunol
, vol.20
, pp. 471-483
-
-
Razmara, M.1
Hilliard, B.2
Ziarani, A.K.3
Chen, Y.H.4
Tykocinski, M.L.5
-
19
-
-
77956399884
-
Cutting edge: CTLA-4-B7 interaction suppresses Th17 cell differentiation
-
Ying, H. et al. Cutting edge: CTLA-4-B7 interaction suppresses Th17 cell differentiation. J. Immunol. 185, 1375-1378 (2010)
-
(2010)
J. Immunol
, vol.185
, pp. 1375-1378
-
-
Ying, H.1
-
20
-
-
19744361931
-
Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b1 myelopoiesis
-
De Klerck, B. et al. Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b1 myelopoiesis. Arthritis Res Ther. 6, R220-231 (2004)
-
(2004)
Arthritis Res Ther
, vol.6
, pp. R220-231
-
-
De Klerck, B.1
-
21
-
-
33747748774
-
Immune interactions with CD41 T cells promote the development of functional osteoclasts from murine CD11c1 dendritic cells
-
Alnaeeli, M., Penninger, J. M. &Teng, Y. T. Immune interactions with CD41 T cells promote the development of functional osteoclasts from murine CD11c1 dendritic cells. J. Immunol. 177, 3314-3326 (2006)
-
(2006)
J. Immunol
, vol.177
, pp. 3314-3326
-
-
Alnaeeli, M.1
Penninger, J.M.2
Teng, Y.T.3
-
22
-
-
77953639101
-
Regulatory T cells protect from local and systemic bone destruction in arthritis
-
Zaiss, M. M. et al. Regulatory T cells protect from local and systemic bone destruction in arthritis. J. Immunol. 184, 7238-7246 (2010)
-
(2010)
J. Immunol
, vol.184
, pp. 7238-7246
-
-
Zaiss, M.M.1
-
23
-
-
47249103596
-
CTLA-4 directly inhibits osteoclast formation
-
Axmann, R. et al. CTLA-4 directly inhibits osteoclast formation. Ann Rheum Dis. 67, 1603-1609 (2008)
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1603-1609
-
-
Axmann, R.1
-
24
-
-
77957656301
-
CTLA-4Ig blocks the development and progression of citrullinated fibrinogen-induced arthritis in DR4-transgenic mice
-
Yue, D. et al. CTLA-4Ig blocks the development and progression of citrullinated fibrinogen-induced arthritis in DR4-transgenic mice. Arthritis Rheum. 62, 2941-2952 (2010)
-
(2010)
Arthritis Rheum
, vol.62
, pp. 2941-2952
-
-
Yue, D.1
-
25
-
-
0034926901
-
Successful gene therapy via intraarticular injection of adenovirus vector containing CTLA4IgG in a murine model of type II collagen-induced arthritis
-
Ijima, K. et al. Successful gene therapy via intraarticular injection of adenovirus vector containing CTLA4IgG in a murine model of type II collagen-induced arthritis. Hum Gene Ther. 12, 1063-1077 (2001)
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1063-1077
-
-
Ijima, K.1
-
26
-
-
30344453083
-
CTLA4Ig introduced by adenovirus vector locally to prolong the survival of xenogeneic skin grafts on rat burn wounds
-
Luo, G. et al. CTLA4Ig introduced by adenovirus vector locally to prolong the survival of xenogeneic skin grafts on rat burn wounds. J. Trauma. 59, 1209-1215 (2005)
-
(2005)
J. Trauma
, vol.59
, pp. 1209-1215
-
-
Luo, G.1
-
27
-
-
0036052121
-
A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome
-
Thummala, N. R. et al. A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome. Gene Ther. 9, 981-990 (2002)
-
(2002)
Gene Ther
, vol.9
, pp. 981-990
-
-
Thummala, N.R.1
-
28
-
-
0033579358
-
Gene therapy death prompts review of adenovirus vector
-
Marshall, E. Gene therapy death prompts review of adenovirus vector. Science 286, 2244-2245 (1999)
-
(1999)
Science
, vol.286
, pp. 2244-2245
-
-
Marshall, E.1
-
29
-
-
0026607937
-
Recombinant mouse prolactin: Expression in Escherichia coli, purification and biological activity
-
Yamamoto, M., Harigaya, T., Ichikawa, T., Hoshino, K. &Nakashima, K. Recombinant mouse prolactin: expression in Escherichia coli, purification and biological activity. J. Mol Endocrinol. 8, 165-172 (1992)
-
(1992)
J. Mol Endocrinol
, vol.8
, pp. 165-172
-
-
Yamamoto, M.1
Harigaya, T.2
Ichikawa, T.3
Hoshino, K.4
Nakashima, K.5
-
30
-
-
0029162499
-
Collageninduced arthritis in the BB rat Prevention of disease by treatment with CTLA-4-Ig
-
Knoerzer, D. B., Karr, R. W., Schwartz, B. D. &Mengle-Gaw, L. J. Collageninduced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig. J. Clin Invest. 96, 987-993 (1995)
-
(1995)
J. Clin Invest
, vol.96
, pp. 987-993
-
-
Knoerzer, D.B.1
Karr, R.W.2
Schwartz, B.D.3
Mengle-Gaw, L.J.4
-
31
-
-
0033664689
-
DNA vaccination: Antigen presentation and the induction of immunity
-
Shedlock, D. J. &Weiner, D. B. DNA vaccination: antigen presentation and the induction of immunity. J. Leukoc Biol. 68, 793-806 (2000)
-
(2000)
J. Leukoc Biol
, vol.68
, pp. 793-806
-
-
Shedlock, D.J.1
Weiner, D.B.2
-
32
-
-
0033850377
-
Direct ex vivo kinetic and phenotypic analyses of CD8 1 T-cell responses induced by DNA immunization
-
Hassett, D. E., Slifka, M. K., Zhang, J. &Whitton, J. L. Direct ex vivo kinetic and phenotypic analyses of CD8(1) T-cell responses induced by DNA immunization. J. Virol. 74, 8286-8291 (2000)
-
(2000)
J. Virol
, vol.74
, pp. 8286-8291
-
-
Hassett, D.E.1
Slifka, M.K.2
Zhang, J.3
Whitton, J.L.4
-
33
-
-
0034005944
-
Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization
-
Hassett, D. E., Zhang, J., Slifka, M. &Whitton, J. L. Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization. J. Virol. 74, 2620-2627 (2000)
-
(2000)
J. Virol
, vol.74
, pp. 2620-2627
-
-
Hassett, D.E.1
Zhang, J.2
Slifka, M.3
Whitton, J.L.4
-
34
-
-
79952187756
-
Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of alpha-L-iduronidase in mice with mucopolysaccharidosis type i
-
Osborn, M. J. et al. Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of alpha-L-iduronidase in mice with mucopolysaccharidosis type I. Mol Ther. 19, 450-460 (2011)
-
(2011)
Mol Ther
, vol.19
, pp. 450-460
-
-
Osborn, M.J.1
-
35
-
-
39849089752
-
Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation
-
Chen, Z. Y., Riu, E.,He, C. Y., Xu, H. &Kay, M. A. Silencing of episomal transgene expression in liver by plasmid bacterial backbone DNA is independent of CpG methylation. Mol Ther. 16, 548-556 (2008)
-
(2008)
Mol Ther
, vol.16
, pp. 548-556
-
-
Chen, Z.Y.1
Riu, E.2
He, C.Y.3
Xu, H.4
Kay, M.A.5
-
36
-
-
2642519089
-
Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo
-
Chen, Z. Y., He, C. Y., Meuse, L. &Kay, M. A. Silencing of episomal transgene expression by plasmid bacterial DNA elements in vivo. Gene Ther. 11, 856-864 (2004)
-
(2004)
Gene Ther
, vol.11
, pp. 856-864
-
-
Chen, Z.Y.1
He, C.Y.2
Meuse, L.3
Kay, M.A.4
-
37
-
-
57149103098
-
Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice
-
Ebina, K. et al. Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice. Biochem Biophys Res Commun. 378, 186-191 (2009)
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 186-191
-
-
Ebina, K.1
-
38
-
-
0028567114
-
Tolerance induction by soluble CTLA4 in a mouse skin transplant model
-
Tepper, M. A., Linsley, P. S., Tritschler, D. &Esselstyn, J. M. Tolerance induction by soluble CTLA4 in a mouse skin transplant model. Transplant Proc. 26, 3151-3154 (1994)
-
(1994)
Transplant Proc
, vol.26
, pp. 3151-3154
-
-
Tepper, M.A.1
Linsley, P.S.2
Tritschler, D.3
Esselstyn, J.M.4
-
39
-
-
34547154756
-
Abatacept treatment does not impair host resistance to chronic mycobacterium tuberculosis infection in mice
-
Haggerty, H. G., Bigbee, C., Gonchoroff, D. G. &Flynn, J. L. Abatacept treatment does not impair host resistance to chronic mycobacterium tuberculosis infection in mice. Ann Rheum Dis. 65, 319-319 (2006)
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 319-319
-
-
Haggerty, H.G.1
Bigbee, C.2
Gonchoroff, D.G.3
Flynn, J.L.4
-
40
-
-
70350503333
-
Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1
-
Huckel, M. et al. Attenuation of murine antigen-induced arthritis by treatment with a decoy oligodeoxynucleotide inhibiting signal transducer and activator of transcription-1 (STAT-1). Arthritis Res Ther. 8, R17 (2006)
-
(2006)
Arthritis Res Ther
, vol.8
, pp. R17
-
-
Huckel, M.1
|