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Volumn 5, Issue , 2014, Pages

SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE SHP 1; HLA ANTIGEN CLASS 1; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY A; PTPN6 PROTEIN, MOUSE;

EID: 84923371706     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6108     Document Type: Article
Times cited : (106)

References (58)
  • 1
    • 84872977452 scopus 로고    scopus 로고
    • Innate lymphoid cells-A proposal for uniform nomenclature
    • Spits, H. et al. Innate lymphoid cells-A proposal for uniform nomenclature. Nat. Rev. Immunol. 13, 145-149 (2013)
    • (2013) Nat. Rev. Immunol , vol.13 , pp. 145-149
    • Spits, H.1
  • 2
    • 78650970845 scopus 로고    scopus 로고
    • Innate or adaptive immunity? the example of natural killer cells
    • Vivier, E. et al. Innate or adaptive immunity? The example of natural killer cells. Science 331, 44-49 (2011)
    • (2011) Science , vol.331 , pp. 44-49
    • Vivier, E.1
  • 3
    • 84898640432 scopus 로고    scopus 로고
    • Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages
    • Klose, C. S. et al. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages. Cell 157, 340-356 (2014)
    • (2014) Cell , vol.157 , pp. 340-356
    • Klose, C.S.1
  • 4
    • 82955182165 scopus 로고    scopus 로고
    • Natural killer cell responses during viral infections: Flexibility and conditioning of innate immunity by experience
    • Vidal, S. M., Khakoo, S. I. &Biron, C. A. Natural killer cell responses during viral infections: flexibility and conditioning of innate immunity by experience. Curr. Opin. Virol. 1, 497-512 (2011)
    • (2011) Curr. Opin. Virol , vol.1 , pp. 497-512
    • Vidal, S.M.1    Khakoo, S.I.2    Biron, C.A.3
  • 5
    • 33947590063 scopus 로고    scopus 로고
    • Whatever turns you on: Accessory-cell-dependent activation of NK cells by pathogens
    • Newman, K. C. &Riley, E. M. Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens. Nat. Rev. Immunol. 7, 279-291 (2007)
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 279-291
    • Newman, K.C.1    Riley, E.M.2
  • 7
    • 79956151449 scopus 로고    scopus 로고
    • Natural killer cell memory
    • Paust, S. &von Andrian, U. H. Natural killer cell memory. Nat. Immunol. 1, 500-508 (2011)
    • (2011) Nat. Immunol , vol.1 , pp. 500-508
    • Paust, S.1    Von Andrian, U.H.2
  • 8
    • 59049094662 scopus 로고    scopus 로고
    • Adaptive immune features of natural killer cells
    • Sun, J. C., Beilke, J. N. &Lanier, L. L. Adaptive immune features of natural killer cells. Nature 457, 557-561 (2009)
    • (2009) Nature , vol.457 , pp. 557-561
    • Sun, J.C.1    Beilke, J.N.2    Lanier, L.L.3
  • 9
    • 33744521309 scopus 로고    scopus 로고
    • Missing self recognition and self tolerance of natural killer (NK) cells
    • Raulet, D. H. Missing self recognition and self tolerance of natural killer (NK) cells. Semin. Immunol. 18, 145-150 (2006)
    • (2006) Semin. Immunol , vol.18 , pp. 145-150
    • Raulet, D.H.1
  • 10
    • 63149126181 scopus 로고    scopus 로고
    • NK cell education: Not an on-off switch but a tunable rheostat
    • Brodin, P., Karre, K. &Hoglund, P. NK cell education: not an on-off switch but a tunable rheostat. Trends Immunol. 30, 143-149 (2009)
    • (2009) Trends Immunol , vol.30 , pp. 143-149
    • Brodin, P.1    Karre, K.2    Hoglund, P.3
  • 11
    • 33644972706 scopus 로고    scopus 로고
    • How do natural killer cells find self to achieve tolerance?
    • Yokoyama, W. M. &Kim, S. How do natural killer cells find self to achieve tolerance? Immunity 24, 249-257 (2006)
    • (2006) Immunity , vol.24 , pp. 249-257
    • Yokoyama, W.M.1    Kim, S.2
  • 12
    • 0022616253 scopus 로고
    • Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defense strategy
    • Kärre, K., Ljunggren, H. G., Piontek, G. &Kiessling, R. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defense strategy. Nature 319, 675-678 (1986)
    • (1986) Nature , vol.319 , pp. 675-678
    • Kärre, K.1    Ljunggren, H.G.2    Piontek, G.3    Kiessling, R.4
  • 13
    • 0026032210 scopus 로고
    • Rejection of class i MHC-deficient haemopoietic cells by irradiated MHC-matched mice
    • Bix, M., Liao, N.-S., Zijlstra, M., Loring, J., Jaenisch, R. &Raulet, D. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice. Nature 349, 329-331 (1991)
    • (1991) Nature , vol.349 , pp. 329-331
    • Bix, M.1    Liao, N.-S.2    Zijlstra, M.3    Loring, J.4    Jaenisch, R.5    Raulet, D.6
  • 14
    • 33745567831 scopus 로고    scopus 로고
    • Self-tolerance of natural killer cells
    • Raulet, D. H. &Vance, R. E. Self-tolerance of natural killer cells. Nat. Rev. Immunol. 6, 520-531 (2006)
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 520-531
    • Raulet, D.H.1    Vance, R.E.2
  • 15
    • 23644458333 scopus 로고    scopus 로고
    • Licensing of natural killer cells by host major histocompatibility complex class i molecules
    • Kim, S. et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436, 709-713 (2005)
    • (2005) Nature , vol.436 , pp. 709-713
    • Kim, S.1
  • 16
    • 18844365992 scopus 로고    scopus 로고
    • A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules
    • Fernandez, N. C. et al. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood 105, 4416-4423 (2005)
    • (2005) Blood , vol.105 , pp. 4416-4423
    • Fernandez, N.C.1
  • 17
    • 33747101972 scopus 로고    scopus 로고
    • Human NK cell education by inhibitory receptors for MHC class i
    • Anfossi, N. et al. Human NK cell education by inhibitory receptors for MHC class I. Immunity 25, 331-342 (2006)
    • (2006) Immunity , vol.25 , pp. 331-342
    • Anfossi, N.1
  • 18
    • 84864138003 scopus 로고    scopus 로고
    • Impaired natural killer cell self-education and missing-self responses in Ly49-deficient mice
    • Belanger, S. et al. Impaired natural killer cell self-education and ''missing-self'' responses in Ly49-deficient mice. Blood 120, 592-602 (2012)
    • (2012) Blood , vol.120 , pp. 592-602
    • Belanger, S.1
  • 19
    • 60449110935 scopus 로고    scopus 로고
    • Natural killer cell tolerance licensing and other mechanisms
    • Jonsson, A. H. &Yokoyama, W. M. Natural killer cell tolerance licensing and other mechanisms. Adv. Immunol. 101, 27-79 (2009)
    • (2009) Adv. Immunol , vol.101 , pp. 27-79
    • Jonsson, A.H.1    Yokoyama, W.M.2
  • 20
    • 65249096787 scopus 로고    scopus 로고
    • NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: The rheostat model
    • Joncker, N. T., Fernandez, N. C., Treiner, E., Vivier, E. &Raulet, D. H. NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J. Immunol. 182, 4572-4580 (2009)
    • (2009) J. Immunol , vol.182 , pp. 4572-4580
    • Joncker, N.T.1    Fernandez, N.C.2    Treiner, E.3    Vivier, E.4    Raulet, D.H.5
  • 21
    • 49249103754 scopus 로고    scopus 로고
    • Immunoreceptor tyrosinebased inhibition motifs: A quest in the past and future
    • Daeron, M., Jaeger, S., Du Pasquier, L. &Vivier, E. Immunoreceptor tyrosinebased inhibition motifs: a quest in the past and future. Immunol. Rev. 224, 11-43 (2008)
    • (2008) Immunol. Rev , vol.224 , pp. 11-43
    • Daeron, M.1    Jaeger, S.2    Du Pasquier, L.3    Vivier, E.4
  • 22
    • 84875528678 scopus 로고    scopus 로고
    • Controlling natural killer cell responses: Integration of signals for activation and inhibition
    • Long, E. O., Kim, H. S., Liu, D., Peterson, M. E. &Rajagopalan, S. Controlling natural killer cell responses: integration of signals for activation and inhibition. Annu. Rev. Immunol. 31, 227-258 (2013)
    • (2013) Annu. Rev. Immunol , vol.31 , pp. 227-258
    • Long, E.O.1    Kim, H.S.2    Liu, D.3    Peterson, M.E.4    Rajagopalan, S.5
  • 23
    • 53349164086 scopus 로고    scopus 로고
    • Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk
    • Peterson, M. E. &Long, E. O. Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk. Immunity 29, 578-588 (2008)
    • (2008) Immunity , vol.29 , pp. 578-588
    • Peterson, M.E.1    Long, E.O.2
  • 24
    • 84860007628 scopus 로고    scopus 로고
    • The adaptor protein Crk controls activation and inhibition of natural killer cells
    • Liu, D., Peterson, M. E. &Long, E. O. The adaptor protein Crk controls activation and inhibition of natural killer cells. Immunity 36, 600-611 (2012)
    • (2012) Immunity , vol.36 , pp. 600-611
    • Liu, D.1    Peterson, M.E.2    Long, E.O.3
  • 25
    • 84887463670 scopus 로고    scopus 로고
    • Education of murine NK cells requires both cis and trans recognition of MHC class i molecules
    • Bessoles, S., Angelov, G. S., Back, J., Leclercq, G., Vivier, E. &Held, W. Education of murine NK cells requires both cis and trans recognition of MHC class I molecules. J. Immunol. 191, 5044-5051 (2013)
    • (2013) J. Immunol , vol.191 , pp. 5044-5051
    • Bessoles, S.1    Angelov, G.S.2    Back, J.3    Leclercq, G.4    Vivier, E.5    Held, W.6
  • 26
    • 61949439062 scopus 로고    scopus 로고
    • A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class i for natural killer cell education
    • Chalifour, A. et al. A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education. Immunity 30, 337-347 (2009)
    • (2009) Immunity , vol.30 , pp. 337-347
    • Chalifour, A.1
  • 27
    • 0034254416 scopus 로고    scopus 로고
    • Impaired natural killing of MHC class i-deficient targets by NK cells expressing a catalytically inactive form of SHP-1
    • Lowin-Kropf, B., Kunz, B., Beermann, F. &Held, W. Impaired natural killing of MHC class i-deficient targets by NK cells expressing a catalytically inactive form of SHP-1. J. Immunol. 165, 1314-1321 (2000)
    • (2000) J. Immunol , vol.165 , pp. 1314-1321
    • Lowin-Kropf, B.1    Kunz, B.2    Beermann, F.3    Held, W.4
  • 28
    • 61849153316 scopus 로고    scopus 로고
    • SHP-1 and SHP-2 in T cells: Two phosphatases functioning at many levels
    • Lorenz, U. SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels. Immunol. Rev. 228, 342-359 (2009)
    • (2009) Immunol. Rev , vol.228 , pp. 342-359
    • Lorenz, U.1
  • 29
    • 81055145276 scopus 로고    scopus 로고
    • Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor
    • Narni-Mancinelli, E. et al. Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptor. Proc. Natl Acad. Sci. USA 108, 18324-18329 (2011)
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 18324-18329
    • Narni-Mancinelli, E.1
  • 30
    • 34447624878 scopus 로고    scopus 로고
    • B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
    • Pao, L. I. et al. B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity. Immunity 27, 35-48 (2007)
    • (2007) Immunity , vol.27 , pp. 35-48
    • Pao, L.I.1
  • 31
    • 34047163529 scopus 로고    scopus 로고
    • KLRG1 binds cadherins and preferentially associates with SHIP-1
    • Tessmer, M. S. et al. KLRG1 binds cadherins and preferentially associates with SHIP-1. Int. Immunol. 19, 391-400 (2007)
    • (2007) Int. Immunol , vol.19 , pp. 391-400
    • Tessmer, M.S.1
  • 32
    • 77951725121 scopus 로고    scopus 로고
    • The NK receptor KLRG1 is dispensable for virusinduced NK and CD8 T-cell differentiation and function in vivo
    • Grundemann, C. et al. The NK receptor KLRG1 is dispensable for virusinduced NK and CD8 T-cell differentiation and function in vivo. Eur. J. Immunol. 40, 1303-1314 (2010)
    • (2010) Eur. J. Immunol , vol.40 , pp. 1303-1314
    • Grundemann, C.1
  • 33
    • 34247170073 scopus 로고    scopus 로고
    • NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation
    • Huntington, N. D. et al. NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation. J. Immunol. 178, 4764-4770 (2007)
    • (2007) J. Immunol , vol.178 , pp. 4764-4770
    • Huntington, N.D.1
  • 34
    • 0034001276 scopus 로고    scopus 로고
    • NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class i molecules
    • Corral, L., Hanke, T., Vance, R. E., Cado, D. &Raulet, D. H. NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules. Eur. J. Immunol. 30, 920-930 (2000)
    • (2000) Eur. J. Immunol , vol.30 , pp. 920-930
    • Corral, L.1    Hanke, T.2    Vance, R.E.3    Cado, D.4    Raulet, D.H.5
  • 35
    • 84857478196 scopus 로고    scopus 로고
    • Skewing of the NK cell repertoire by MHC class i via quantitatively controlled enrichment and contraction of specific Ly49 subsets
    • Brodin, P., Lakshmikanth, T., Karre, K. &Hoglund, P. Skewing of the NK cell repertoire by MHC class I via quantitatively controlled enrichment and contraction of specific Ly49 subsets. J. Immunol. 188, 2218-2226 (2012)
    • (2012) J. Immunol , vol.188 , pp. 2218-2226
    • Brodin, P.1    Lakshmikanth, T.2    Karre, K.3    Hoglund, P.4
  • 36
    • 79953840956 scopus 로고    scopus 로고
    • Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance
    • Guia, S., Jaeger, B. N., Piatek, S., Mailfert, S., Trombik, T. &Fenis, A. et al. Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. Sci. Signal. 4, ra21 (2011)
    • (2011) Sci. Signal , vol.4 , pp. 21
    • Guia, S.1    Jaeger, B.N.2    Piatek, S.3    Mailfert, S.4    Trombik, T.5    Fenis, A.6
  • 37
    • 84866411174 scopus 로고    scopus 로고
    • A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples
    • Chicanne, G. et al. A novel mass assay to quantify the bioactive lipid PtdIns3P in various biological samples. Biochem. J. 447, 17-23 (2012)
    • (2012) Biochem. J , vol.447 , pp. 17-23
    • Chicanne, G.1
  • 38
    • 0025789740 scopus 로고
    • Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m-mice: Nonresponsiveness controlled by beta 2m-bone marrow in chimeric mice
    • Hoglund, P. et al. Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m-mice: nonresponsiveness controlled by beta 2m-bone marrow in chimeric mice. Proc. Natl Acad. Sci. USA 88, 10332-10336 (1991)
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 10332-10336
    • Hoglund, P.1
  • 39
    • 3242731492 scopus 로고    scopus 로고
    • Loss or mismatch of MHC class i is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo-role of KARAP/DAP12-dependent and-independent pathways
    • Oberg, L. et al. Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo-role of KARAP/DAP12-dependent and-independent pathways. Eur. J. Immunol. 34, 1646-1653 (2004)
    • (2004) Eur. J. Immunol , vol.34 , pp. 1646-1653
    • Oberg, L.1
  • 40
    • 80053371978 scopus 로고    scopus 로고
    • IFN-{gamma} production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice
    • Takeda, K. et al. IFN-{gamma} production by lung NK cells is critical for the natural resistance to pulmonary metastasis of B16 melanoma in mice. J. Leukoc. Biol. 90, 777-785 (2011)
    • (2011) J. Leukoc. Biol , vol.90 , pp. 777-785
    • Takeda, K.1
  • 41
    • 84880683223 scopus 로고    scopus 로고
    • Shp1 regulates T cell homeostasis by limiting IL-4 signals
    • Johnson, D. J. et al. Shp1 regulates T cell homeostasis by limiting IL-4 signals. J. Exp. Med. 210, 1419-1431 (2013)
    • (2013) J. Exp. Med , vol.210 , pp. 1419-1431
    • Johnson, D.J.1
  • 42
    • 78650663108 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells
    • Iype, T., Sankarshanan, M., Mauldin, I. S., Mullins, D. W. &Lorenz, U. The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells. J. Immunol. 185, 6115-6127 (2010)
    • (2010) J. Immunol , vol.185 , pp. 6115-6127
    • Iype, T.1    Sankarshanan, M.2    Mauldin, I.S.3    Mullins, D.W.4    Lorenz, U.5
  • 43
    • 84875532599 scopus 로고    scopus 로고
    • Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice
    • Abram, C. L., Roberge, G. L., Pao, L. I., Neel, B. G. &Lowell, C. A. Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice. Immunity 38, 489-501 (2013)
    • (2013) Immunity , vol.38 , pp. 489-501
    • Abram, C.L.1    Roberge, G.L.2    Pao, L.I.3    Neel, B.G.4    Lowell, C.A.5
  • 44
    • 84859891065 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases in lymphocyte activation and autoimmunity
    • Rhee, I. &Veillette, A. Protein tyrosine phosphatases in lymphocyte activation and autoimmunity. Nat. Immunol. 13, 439-447 (2012)
    • (2012) Nat. Immunol , vol.13 , pp. 439-447
    • Rhee, I.1    Veillette, A.2
  • 45
    • 84865617411 scopus 로고    scopus 로고
    • SHP-1 phosphatase is a critical regulator in preventing natural killer cell self-killing
    • Mahmood, S., Kanwar, N., Tran, J., Zhang, M. L. &Kung, S. K. SHP-1 phosphatase is a critical regulator in preventing natural killer cell self-killing. PLoS ONE 7, e44244 (2012)
    • (2012) PLoS ONE , vol.7 , pp. e44244
    • Mahmood, S.1    Kanwar, N.2    Tran, J.3    Zhang, M.L.4    Kung, S.K.5
  • 46
    • 77955272838 scopus 로고    scopus 로고
    • SLAM-family receptors: Immune regulators with or without SAP-family adaptors
    • Veillette, A. SLAM-family receptors: immune regulators with or without SAP-family adaptors. Cold Spring Harb. Perspect. Biol. 2, a002469 (2010)
    • (2010) Cold Spring Harb. Perspect. Biol , vol.2 , pp. a002469
    • Veillette, A.1
  • 47
    • 84859162436 scopus 로고    scopus 로고
    • Receptors that interact with nectin and nectin-like proteins in the immunosurveillance and immunotherapy of cancer
    • Chan, C. J., Andrews, D. M. &Smyth, M. J. Receptors that interact with nectin and nectin-like proteins in the immunosurveillance and immunotherapy of cancer. Curr. Opin. Immunol. 24, 246-251 (2012)
    • (2012) Curr. Opin. Immunol , vol.24 , pp. 246-251
    • Chan, C.J.1    Andrews, D.M.2    Smyth, M.J.3
  • 48
    • 43549123826 scopus 로고    scopus 로고
    • Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways
    • Coudert, J. D., Scarpellino, L., Gros, F., Vivier, E. &Held, W. Sustained NKG2D engagement induces cross-tolerance of multiple distinct NK cell activation pathways. Blood 111, 3571-3578 (2008)
    • (2008) Blood , vol.111 , pp. 3571-3578
    • Coudert, J.D.1    Scarpellino, L.2    Gros, F.3    Vivier, E.4    Held, W.5
  • 49
    • 24944500112 scopus 로고    scopus 로고
    • Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance
    • Oppenheim, D. E., Roberts, S. J., Clarke, S. L., Filler, R., Lewis, J. M. &Tigelaar, R. E. et al. Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance. Nat. Immunol. 6, 928-937 (2005)
    • (2005) Nat. Immunol , vol.6 , pp. 928-937
    • Oppenheim, D.E.1    Roberts, S.J.2    Clarke, S.L.3    Filler, R.4    Lewis, J.M.5    Tigelaar, R.E.6
  • 50
    • 49249086644 scopus 로고    scopus 로고
    • Continuous engagement of a self-specific activation receptor induces NK cell tolerance
    • Tripathy, S. K., Keyel, P. A., Yang, L., Pingel, J. T., Cheng, T. P. &Schneeberger, A. et al. Continuous engagement of a self-specific activation receptor induces NK cell tolerance. J. Exp. Med. 205, 1829-1841 (2008)
    • (2008) J. Exp. Med , vol.205 , pp. 1829-1841
    • Tripathy, S.K.1    Keyel, P.A.2    Yang, L.3    Pingel, J.T.4    Cheng, T.P.5    Schneeberger, A.6
  • 51
    • 49249088692 scopus 로고    scopus 로고
    • Tolerance of NK cells encountering their viral ligand during development
    • Sun, J. C. &Lanier, L. L. Tolerance of NK cells encountering their viral ligand during development. J. Exp. Med. 205, 1819-1828 (2008)
    • (2008) J. Exp. Med , vol.205 , pp. 1819-1828
    • Sun, J.C.1    Lanier, L.L.2
  • 52
    • 77949532253 scopus 로고    scopus 로고
    • Education of human natural killer cells by activating killer cell immunoglobulin-like receptors
    • Fauriat, C., Ivarsson, M. A., Ljunggren, H. G., Malmberg, K. J. &Michaelsson, J. Education of human natural killer cells by activating killer cell immunoglobulin-like receptors. Blood 115, 1166-1174 (2010)
    • (2010) Blood , vol.115 , pp. 1166-1174
    • Fauriat, C.1    Ivarsson, M.A.2    Ljunggren, H.G.3    Malmberg, K.J.4    Michaelsson, J.5
  • 53
    • 9444249908 scopus 로고    scopus 로고
    • Natural killer cell signaling pathways
    • Vivier, E., Nunes, J. A. &Vely, F. Natural killer cell signaling pathways. Science 306, 1517-1519 (2004)
    • (2004) Science , vol.306 , pp. 1517-1519
    • Vivier, E.1    Nunes, J.A.2    Vely, F.3
  • 54
    • 0036915968 scopus 로고    scopus 로고
    • Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D
    • Diefenbach, A. et al. Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat. Immunol. 3, 1142-1149 (2002)
    • (2002) Nat. Immunol , vol.3 , pp. 1142-1149
    • Diefenbach, A.1
  • 55
    • 33645976783 scopus 로고    scopus 로고
    • NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells
    • Upshaw, J. L. et al. NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells. Nat. Immunol. 7, 524-532 (2006)
    • (2006) Nat. Immunol , vol.7 , pp. 524-532
    • Upshaw, J.L.1
  • 56
    • 42449102990 scopus 로고    scopus 로고
    • Up on the tightrope: Natural killer cell activation and inhibition
    • Lanier, L. L. Up on the tightrope: natural killer cell activation and inhibition. Nat. Immunol. 9, 495-502 (2008)
    • (2008) Nat. Immunol , vol.9 , pp. 495-502
    • Lanier, L.L.1
  • 57
    • 0036210733 scopus 로고    scopus 로고
    • A role for the src family kinase fyn in nk cell activation and the formation of the repertoire of Ly49 receptors
    • Lowin-Kropf, B., Kunz, B., Schneider, P. &Held, W. A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors. Eur. J. Immunol. 32, 773-782 (2002)
    • (2002) Eur. J. Immunol , vol.32 , pp. 773-782
    • Lowin-Kropf, B.1    Kunz, B.2    Schneider, P.3    Held, W.4
  • 58
    • 57849145994 scopus 로고    scopus 로고
    • Influence of the transcription factor RORgammat on the development of NKp46() cell populations in gut and skin
    • Luci, C. et al. Influence of the transcription factor RORgammat on the development of NKp46() cell populations in gut and skin. Nat. Immunol. 10, 75-82 (2009)
    • (2009) Nat. Immunol , vol.10 , pp. 75-82
    • Luci, C.1


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