The V510D suppressor mutation stabilizes Δf508-CFTR at the cell surface

Biochemistry

Volumn 49, Issue 30, 2010, Pages 6352-6357

  Loo, Tip W ^a   Bartlett, M Claire ^a   Clarke, David M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDIC RESIDUES; CELL SURFACES; CYSTIC FIBROSIS; FULL-LENGTH PROTEINS; NUCLEOTIDE-BINDING DOMAIN; SALT BRIDGES; SECOND TRANSMEMBRANE DOMAIN; WILD TYPES;

ACTIVATION ANALYSIS; PROTEINS; RADIOACTIVITY;

CELL MEMBRANES;

ARGININE; MEMBRANE PROTEIN; PHENYLALANINE; TRANSMEMBRANE CONDUCTANCE REGULATOR; VALINE;

AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; CELL STRAIN BHK; CELL STRAIN HEK293; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MUTANT; MUTATION; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; WILD TYPE;

AMINO ACIDS, ACIDIC; CELL LINE; CELL MEMBRANE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HALF-LIFE; HUMANS; MUTATION, MISSENSE; PROTEIN CONFORMATION; PROTEIN STABILITY;

EID: 77955025743     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi100807h     Document Type: Article

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