Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: An electronic medical record-based genome-wide association study

G3: Genes, Genomes, Genetics

Volumn 3, Issue 7, 2013, Pages 1061-1068

  Ding, Keyue ^a   Andrade, Mariza de ^c   Manolio, Teri A ^d   Crawford, Dana C ^f   Rasmussen Torvik, Laura J ⁱ   Ritchie, Marylyn D ^g   Denny, Joshua C ^e   Masys, Daniel R ^h   Jouni, Hayan ^b   Pachecho, Jennifer A ^j   Kho, Abel N ^j   Roden, Dan M ^e   Chisholm, Rex ⁱ   Kullo, Iftikhar J ^a  

^a Mayo Clinic   (United States)

^b Department of Internal Medicine ^*  (United States)

^c MAYO CLINIC   (United States)

^d NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^g PENNSYLVANIA STATE UNIVERSITY   (United States)

^h UNIVERSITY OF WASHINGTON   (United States)

ⁱ NORTHWESTERN UNIVERSITY   (United States)

^j NORTHWESTERN UNIVERSITY   (United States)

more..

Author keywords

African Americans; Association study; Electronic medical; Genome wide; Informatics; Natural selection; Record; Red blood cell (RBC); Traits

Indexed keywords

GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEMOGLOBIN;

ADULT; AFRICAN AMERICAN; AFRICAN-AMERICANS; ARTICLE; BLOOD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE RESISTANCE; ELECTRONIC MEDICAL RECORD; ERYTHROCYTE; ERYTHROCYTE COUNT; FEMALE; GENE IDENTIFICATION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENETICS; GENOTYPE; HEMATOCRIT; HEMOGLOBIN DETERMINATION; HUMAN; HUMAN CELL; INFORMATION SCIENCE; MAJOR CLINICAL STUDY; MALARIA; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; NATURAL SELECTION; PATHOLOGY; RED BLOOD CELL (RBC) TRAITS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84883213248     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.113.006452     Document Type: Article

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