-
1
-
-
84855753457
-
Targeting of substance P induces cancer cell death and decreases the steady state of EGFR and Her2
-
Mayordomo, C. et al. Targeting of substance P induces cancer cell death and decreases the steady state of EGFR and Her2. J. Cell. Physiol. 227, 1358-1366 (2012)
-
(2012)
J. Cell. Physiol
, vol.227
, pp. 1358-1366
-
-
Mayordomo, C.1
-
2
-
-
0032568444
-
Altered nociception, analgesia and aggression in mice lacking the receptor for substance P
-
Felipe, C. D. et al. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 392, 394-397 (1998)
-
(1998)
Nature
, vol.392
, pp. 394-397
-
-
Felipe, C.D.1
-
3
-
-
33748709410
-
Neurokinin-1 receptor blockade and murine lung tumorigenesis
-
Lucattelli, M., Fineschi, S., Geppetti, P., Gerard, N. P. &Lungarella, G. Neurokinin-1 receptor blockade and murine lung tumorigenesis. Am. J. Respir. Crit. Care Med. 174, 674-683 (2006)
-
(2006)
Am. J. Respir. Crit. Care Med
, vol.174
, pp. 674-683
-
-
Lucattelli, M.1
Fineschi, S.2
Geppetti, P.3
Gerard, N.P.4
Lungarella, G.5
-
4
-
-
33747199597
-
Tachykinins and their receptors in human malignancies
-
Palma, C. Tachykinins and their receptors in human malignancies. Curr. Drug Targets 7, 1043-1052 (2006)
-
(2006)
Curr. Drug Targets
, vol.7
, pp. 1043-1052
-
-
Palma, C.1
-
5
-
-
56549097852
-
Cell proliferation associated with actions of the substance P/NK-1 receptor complex in keratocystic odontogenic tumours
-
Moles, G. et al. Cell proliferation associated with actions of the substance P/NK-1 receptor complex in keratocystic odontogenic tumours. Oral Oncol. 44, 1127-1133 (2008)
-
(2008)
Oral Oncol
, vol.44
, pp. 1127-1133
-
-
Moles, G.1
-
6
-
-
0022929837
-
Binding characteristics and affinity labeling of protein constituents of the human IM-9 lymphoblast receptor for substance P
-
Payan, D. G., McGillis, J. P. &Organist, M. L. Binding characteristics and affinity labeling of protein constituents of the human IM-9 lymphoblast receptor for substance P. J. Biol. Chem. 261, 14321-14329 (1986)
-
(1986)
J. Biol. Chem
, vol.261
, pp. 14321-14329
-
-
Payan, D.G.1
McGillis, J.P.2
Organist, M.L.3
-
7
-
-
0028078691
-
Substance P enhances forskolin-stimulated cyclic AMP production in human UC11MG astrocytoma cells
-
Fowler, C. J. &Brännström, G. Substance P enhances forskolin-stimulated cyclic AMP production in human UC11MG astrocytoma cells. Methods Find. Exp. Clin. Pharmacol. 16, 21-28 (1993)
-
(1993)
Methods Find. Exp. Clin. Pharmacol
, vol.16
, pp. 21-28
-
-
Fowler, C.J.1
Brännström, G.2
-
8
-
-
84882491636
-
Involvement of substance P and the NK-1 receptor in cancer progression
-
Munoz, M. &Covenas, R. Involvement of substance P and the NK-1 receptor in cancer progression. Peptides 48, 1-9 (2013)
-
(2013)
Peptides
, vol.48
, pp. 1-9
-
-
Munoz, M.1
Covenas, R.2
-
9
-
-
84894164264
-
Targeted Theranostic Platinum(IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ
-
Yuan, Y., Kwok, R. T. K., Tang, B. Z. &Liu, B. Targeted Theranostic Platinum(IV) prodrug with a built-in aggregation-induced emission light-up apoptosis sensor for noninvasive early evaluation of its therapeutic responses in situ. J. Am. Chem. Soc. 136, 2546-2554 (2014)
-
(2014)
J. Am. Chem. Soc
, vol.136
, pp. 2546-2554
-
-
Yuan, Y.1
Kwok, R.T.K.2
Tang, B.Z.3
Liu, B.4
-
10
-
-
0038004636
-
Clinical biomarkers in drug discovery and development
-
Frank, R. &Hargreaves, R. Clinical biomarkers in drug discovery and development. Nat. Rev. Drug Discov. 2, 566-580 (2003)
-
(2003)
Nat. Rev. Drug Discov
, vol.2
, pp. 566-580
-
-
Frank, R.1
Hargreaves, R.2
-
11
-
-
78649861704
-
Lung cancer serum biomarker discovery using glycoprotein capture and liquid chromatography mass spectrometry
-
Zeng, X. et al. Lung cancer serum biomarker discovery using glycoprotein capture and liquid chromatography mass spectrometry. J. Proteome Res. 9, 6440-6449 (2010)
-
(2010)
J. Proteome Res
, vol.9
, pp. 6440-6449
-
-
Zeng, X.1
-
12
-
-
77956784218
-
Early detection and screening of lung cancer
-
Mascaux, C. et al. Early detection and screening of lung cancer. Expert. Rev. Mol. Diagn. 10, 799-815 (2010)
-
(2010)
Expert. Rev. Mol. Diagn
, vol.10
, pp. 799-815
-
-
Mascaux, C.1
-
13
-
-
4544250024
-
A Gene-promoter hypermethylation as a biomarker in lung cancer
-
Belinsky, S. A. Gene-promoter hypermethylation as a biomarker in lung cancer. Nat. Rev. Cancer 4, 707-717 (2004)
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 707-717
-
-
Belinsky, S.1
-
14
-
-
33847749502
-
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer
-
Spira, A. et al. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nat. Med. 13, 361-366 (2007)
-
(2007)
Nat. Med
, vol.13
, pp. 361-366
-
-
Spira, A.1
-
15
-
-
84876131678
-
Aptamers from cell-based selection for bioanalytical applications
-
Tan, W., Donovan, M. J. &Jiang, J. Aptamers from cell-based selection for bioanalytical applications. Chem. Rev. 113, 2842-2862 (2013)
-
(2013)
Chem. Rev
, vol.113
, pp. 2842-2862
-
-
Tan, W.1
Donovan, M.J.2
Jiang, J.3
-
16
-
-
84902594395
-
Functional DNA-containing nanomaterials: Cellular applications in biosensing, imaging, and targeted therapy
-
Liang, H. et al. Functional DNA-containing nanomaterials: cellular applications in biosensing, imaging, and targeted therapy. Acc. Chem. Res. 47, 1891-1901 (2014)
-
(2014)
Acc. Chem. Res
, vol.47
, pp. 1891-1901
-
-
Liang, H.1
-
17
-
-
84887758806
-
Noncanonical self-Assembly of multifunctional DNA nanoflowers for biomedical applications
-
Zhu, G. et al. Noncanonical self-Assembly of multifunctional DNA nanoflowers for biomedical applications. J. Am. Chem. Soc. 135, 16438-16445 (2013)
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 16438-16445
-
-
Zhu, G.1
-
18
-
-
10344260928
-
An enantioselective fluorescent sensor for sugar acids
-
Zhao, J., Davidson, M. G., Mahon, M. F., Kociok-Köhn, G. &James, T. D. An enantioselective fluorescent sensor for sugar acids. J. Am. Chem. Soc. 126, 16179-16186 (2004)
-
(2004)
J. Am. Chem. Soc
, vol.126
, pp. 16179-16186
-
-
Zhao, J.1
Davidson, M.G.2
Mahon, M.F.3
Kociok-Köhn, G.4
James, T.D.5
-
19
-
-
79959513247
-
Peptide functionalized polydiacetylene liposomes act as a fluorescent turn-on sensor for bacterial lipopolysaccharide
-
Wu, J., Zawistowski, A., Ehrmann, M., Yi, T. &Schmuck, C. Peptide functionalized polydiacetylene liposomes act as a fluorescent turn-on sensor for bacterial lipopolysaccharide. J. Am. Chem. Soc. 133, 9720-9723 (2011)
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 9720-9723
-
-
Wu, J.1
Zawistowski, A.2
Ehrmann, M.3
Yi, T.4
Schmuck, C.5
-
20
-
-
84555186976
-
In vivo detection of phospholipase C by enzyme-Activated nearinfrared probes
-
Mawn, T.M. et al. In vivo detection of phospholipase C by enzyme-Activated nearinfrared probes. Bioconjugate Chem. 22, 2434-2443 (2011)
-
(2011)
Bioconjugate Chem
, vol.22
, pp. 2434-2443
-
-
Mawn, T.M.1
-
21
-
-
84883465373
-
Bioprobes based on AIE fluorogens
-
Ding, D., Li, K., Liu, B. &Tang, B. Z. Bioprobes based on AIE fluorogens. Acc. Chem. Res. 46, 2441-2453 (2013)
-
(2013)
Acc. Chem. Res
, vol.46
, pp. 2441-2453
-
-
Ding, D.1
Li, K.2
Liu, B.3
Tang, B.Z.4
-
22
-
-
84896447671
-
A Quantitative relaxometric version of the ELISA test for the measurement of cell surface biomarkers
-
Alberti, D. et al. A Quantitative relaxometric version of the ELISA test for the measurement of cell surface biomarkers. Angew. Chem., Int. Ed. 53, 3488-3491 (2014)
-
(2014)
Angew. Chem Int. Ed
, vol.53
, pp. 3488-3491
-
-
Alberti, D.1
-
23
-
-
33746927937
-
In vitro and in vivo magnetic resonance detection of tumor cells by targeting glutamine transporters with Gd-based probes
-
Crich, G. et al. In vitro and in vivo magnetic resonance detection of tumor cells by targeting glutamine transporters with Gd-based probes. J. Med. Chem. 49, 4926-4936 (2006)
-
(2006)
J. Med. Chem
, vol.49
, pp. 4926-4936
-
-
Crich, G.1
-
24
-
-
76749109078
-
Ultrasmall near-infrared non-cadmium quantum dots for in vivo tumor imaging
-
Gao, J. et al. Ultrasmall near-infrared non-cadmium quantum dots for in vivo tumor imaging. Small 6, 256-261 (2010)
-
(2010)
Small
, vol.6
, pp. 256-261
-
-
Gao, J.1
-
25
-
-
79957823184
-
Integrin targeting for tumor optical imaging
-
Ye, Y. &Chen, X. Integrin targeting for tumor optical imaging. Theranostics 1, 102-126 (2011)
-
(2011)
Theranostics
, vol.1
, pp. 102-126
-
-
Ye, Y.1
Chen, X.2
-
26
-
-
84883723881
-
A Targeted, self-delivered, and photocontrolled molecular beacon for mRNA detection in living cells
-
Qiu, L. et al. A Targeted, self-delivered, and photocontrolled molecular beacon for mRNA detection in living cells. J. Am. Chem. Soc. 135, 12952-12955 (2013)
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 12952-12955
-
-
Qiu, L.1
-
27
-
-
84860478432
-
Aptamer-enabled efficient isolation of cancer cells from whole blood using a microfluidic device
-
Sheng, W. et al. Aptamer-enabled efficient isolation of cancer cells from whole blood using a microfluidic device. Anal. Chem. 84, 4199-4206 (2012)
-
(2012)
Anal. Chem
, vol.84
, pp. 4199-4206
-
-
Sheng, W.1
-
28
-
-
84872408063
-
MRI visualization of melanoma cells by targeting overexpressed sialic acid with a Gd(III)-dota-en-pba imaging reporter
-
Geninatti Crich, S., Alberti, D., Szabo, I., Aime, S. &Djanashvili, K. MRI visualization of melanoma cells by targeting overexpressed sialic acid with a Gd(III)-dota-en-pba imaging reporter. Angew. Chem. Int. Ed. Engl. 52, 1161-1164 (2013)
-
(2013)
Angew. Chem. Int. Ed. Engl
, vol.52
, pp. 1161-1164
-
-
Geninatti Crich, S.1
Alberti, D.2
Szabo, I.3
Aime, S.4
Djanashvili, K.5
-
29
-
-
1942439040
-
Folate receptor endocytosis and trafficking
-
Sabharanjak, S.&Mayor, S. Folate receptor endocytosis and trafficking. Adv. Drug Delivery. Rev. 56, 1099-1109 (2004)
-
(2004)
Adv. Drug Delivery. Rev
, vol.56
, pp. 1099-1109
-
-
Sabharanjak, S.1
Mayor, S.2
-
30
-
-
70350717069
-
Molecular imaging in cardiovascular disease: Targets and opportunities
-
Shaw, S. Y. Molecular imaging in cardiovascular disease: targets and opportunities. Nat. Rev. Cardiol. 6, 569-579 (2009)
-
(2009)
Nat. Rev. Cardiol
, vol.6
, pp. 569-579
-
-
Shaw, S.Y.1
-
31
-
-
84896953219
-
The role of 'disaggregation' in optical probe development
-
Zhai, D., Xu, W., Zhang, L. &Chang, Y.-T. The role of 'disaggregation' in optical probe development. Chem. Soc. Rev. 43, 2402-2411 (2014)
-
(2014)
Chem. Soc. Rev
, vol.43
, pp. 2402-2411
-
-
Zhai, D.1
Xu, W.2
Zhang, L.3
Chang, Y.-T.4
-
32
-
-
0029057535
-
Themammalian tachykinin receptors
-
Maggi, C. A. Themammalian tachykinin receptors. Gen. Pharmacol. 26, 911-944 (1995)
-
(1995)
Gen. Pharmacol
, vol.26
, pp. 911-944
-
-
Maggi, C.A.1
-
33
-
-
0347914570
-
Tachykinins and tachykinin receptors: A growing family
-
Pennefather, J. N. et al. Tachykinins and tachykinin receptors: a growing family. Life Sci. 74, 1445-1463 (2004)
-
(2004)
Life Sci
, vol.74
, pp. 1445-1463
-
-
Pennefather, J.N.1
-
34
-
-
31444441701
-
New approaches to antidepressant drug discovery: Beyond monoamines
-
Berton, O. &Nestler, E. J. New approaches to antidepressant drug discovery: beyond monoamines. Nat. Rev. Neurosci. 7, 137-151 (2006)
-
(2006)
Nat. Rev. Neurosci
, vol.7
, pp. 137-151
-
-
Berton, O.1
Nestler, E.J.2
-
35
-
-
79958793690
-
Switchable supramolecular polymers from the self-Assembly of a small monomer with two orthogonal binding interactions
-
Gröger, G. et al. Switchable supramolecular polymers from the self-Assembly of a small monomer with two orthogonal binding interactions. J. Am. Chem. Soc. 133, 8961-8971 (2011)
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 8961-8971
-
-
Gröger, G.1
-
36
-
-
0038294530
-
Photoelectric conversion properties of four novel carboxylated hemicyanine dyes on TiO2 electrode
-
Yao, Q.-H., Meng, F.-S., Li, F.-Y., Tian, H. &Huang, C.-H. Photoelectric conversion properties of four novel carboxylated hemicyanine dyes on TiO2 electrode. J. Mater. Chem. 13, 1048-1053 (2003)
-
(2003)
J. Mater. Chem
, vol.13
, pp. 1048-1053
-
-
Yao, Q.-H.1
Meng, F.-S.2
Li, F.-Y.3
Tian, H.4
Huang, C.-H.5
-
37
-
-
84975565170
-
Absorption and second-harmonic generation of monomer and aggregate hemicyanine dye in Langmuir-Blodgett films
-
Schildkraut, J. S., Penner, T. L., Willand, C. S. &Ulman, A. Absorption and second-harmonic generation of monomer and aggregate hemicyanine dye in Langmuir-Blodgett films. Opt. Lett. 13, 134-136 (1988)
-
(1988)
Opt. Lett
, vol.13
, pp. 134-136
-
-
Schildkraut, J.S.1
Penner, T.L.2
Willand, C.S.3
Ulman, A.4
-
38
-
-
77952983319
-
Changing the behavior of cChromophores from aggregationcaused quenching to aggregation-induced emission: Development of highly efficient light emitters in the solid state
-
Yuan, W. Z. et al. Changing the behavior of cChromophores from aggregationcaused quenching to aggregation-induced emission: development of highly efficient light emitters in the solid state. Adv. Mater. 22, 2159-2163 (2010)
-
(2010)
Adv. Mater
, vol.22
, pp. 2159-2163
-
-
Yuan, W.Z.1
-
39
-
-
14844309304
-
High molecular weight supramolecular polymers containing both terpyridine metal complexes and ureidopyrimidinone quadruple hydrogen-bonding units in the main chain
-
Hofmeier, H., Hoogenboom, R., Wouters, M. E. &Schubert, U. S. High molecular weight supramolecular polymers containing both terpyridine metal complexes and ureidopyrimidinone quadruple hydrogen-bonding units in the main chain. J. Am. Chem. Soc. 127, 2913-2921 (2005)
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 2913-2921
-
-
Hofmeier, H.1
Hoogenboom, R.2
Wouters, M.E.3
Schubert, U.S.4
-
40
-
-
70350067813
-
Analysis of the interaction of BCL9 with b-catenin and development of fluorescence polarization and surface plasmon resonance binding assays for this interaction
-
Kawamoto, S. A. et al. Analysis of the interaction of BCL9 with b-catenin and development of fluorescence polarization and surface plasmon resonance binding assays for this interaction. Biochemistry 48, 9534-9541 (2009)
-
(2009)
Biochemistry
, vol.48
, pp. 9534-9541
-
-
Kawamoto, S.A.1
-
41
-
-
84875787224
-
Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery
-
Zhang, J. et al.Multifunctional envelope-type mesoporous silica nanoparticles for tumor-triggered targeting drug delivery. J. Am. Chem. Soc. 135, 5068-5073 (2013)
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 5068-5073
-
-
Zhang, J.1
-
42
-
-
80052088414
-
Engineering Polymeric Aptamers for Selective Cytotoxicity
-
Yang, L. et al. Engineering Polymeric Aptamers for Selective Cytotoxicity. J. Am. Chem. Soc. 133, 13380-13386 (2011)
-
(2011)
J. Am. Chem. Soc
, vol.133
, pp. 13380-13386
-
-
Yang, L.1
-
43
-
-
6044249967
-
Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: Theory and design
-
Lauffer, R. B. Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: theory and design. Chem. Rev. 87, 901-927 (1987)
-
(1987)
Chem. Rev
, vol.87
, pp. 901-927
-
-
Lauffer, R.B.1
-
44
-
-
33744516119
-
Strategies for increasing the sensitivity of gadolinium based MRI contrast agents
-
Caravan, P. Strategies for increasing the sensitivity of gadolinium based MRI contrast agents. Chem. Soc. Rev. 35, 512 (2006)
-
(2006)
Chem. Soc. Rev
, vol.35
, pp. 512
-
-
Caravan, P.1
-
45
-
-
84870171728
-
Macromolecular imaging agents containing lanthanides: Can conceptual promise lead to clinical potential?
-
Bryson, J. M., Reineke, J. W. &Reineke, T. M. Macromolecular imaging agents containing lanthanides: can conceptual promise lead to clinical potential? Macromolecules 45, 8939-8952 (2012)
-
(2012)
Macromolecules
, vol.45
, pp. 8939-8952
-
-
Bryson, J.M.1
Reineke, J.W.2
Reineke, T.M.3
-
46
-
-
0027348306
-
Status of liposomes as MR contrast agents
-
Unger, E. C., Shen, D.-K. &Fritz, T. A. Status of liposomes as MR contrast agents. J. Magn. Reson. Imaging 3, 195-198 (1993)
-
(1993)
J. Magn. Reson. Imaging
, vol.3
, pp. 195-198
-
-
Unger, E.C.1
Shen, D.-K.2
Fritz, T.A.3
-
47
-
-
84870715518
-
Gd (DOTAla): A single amino acid Gd-complex as amodular tool for high relaxivityMRcontrast agent development
-
Boros, E., Polasek, M., Zhang, Z. &Caravan, P. Gd (DOTAla): a single amino acid Gd-complex as amodular tool for high relaxivityMRcontrast agent development. J. Am. Chem. Soc. 134, 19858-19868 (2012)
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 19858-19868
-
-
Boros, E.1
Polasek, M.2
Zhang, Z.3
Caravan, P.4
-
48
-
-
0029071971
-
Substance-P receptors in human primary neoplasms: Tumoral and vascular localization
-
Hennig, I. M., Laissue, J. A., Horisberger, U. &Reubi, J.-C. Substance-P receptors in human primary neoplasms: Tumoral and vascular localization. Int. J. Cancer 61, 786-792 (1995)
-
(1995)
Int. J. Cancer
, vol.61
, pp. 786-792
-
-
Hennig, I.M.1
Laissue, J.A.2
Horisberger, U.3
Reubi, J.-C.4
-
49
-
-
0036022520
-
Magnetic relaxation switches capable of sensing molecular interactions
-
Perez, J. M., Josephson, L., O'Loughlin, T., Högemann, D. &Weissleder, R. Magnetic relaxation switches capable of sensing molecular interactions. Nat. Biotechnol. 20, 816-820 (2002)
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 816-820
-
-
Perez, J.M.1
Josephson, L.2
O'loughlin, T.3
Högemann, D.4
Weissleder, R.5
|