Cell proliferation associated with actions of the substance P/NK-1 receptor complex in keratocystic odontogenic tumours

Oral Oncology

Volumn 44, Issue 12, 2008, Pages 1127-1133

  Gonzalez Moles M A ^a   Mosqueda Taylor, A ^b   Esteban, F ^c   Gil Montoya, J A ^a   Diaz Franco M A ^b   Delgado, M ^d   Munoz M ^c  

^a UNIVERSITY OF GRANADA   (Spain)

^b DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

^c HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^d UNIVERSITY OF JAÉN   (Spain)

Author keywords

Keratocystic odontogenic; NK 1R; Substance P

Indexed keywords

BIOLOGICAL MARKER; KI 67 ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY KI 67; NK 1 RECEPTOR; RECEPTOR; SUBSTANCE P; SUBSTANCE P ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ANTIGEN EXPRESSION; ARTICLE; BASAL CELL NEVUS SYNDROME; CELL MEMBRANE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; EPITHELIUM CELL; EPITHELIUM DYSPLASIA; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATOCYSTIC ODONTOGENIC TUMOR; LYMPHOCYTE; MALE; ODONTOGENIC TUMOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

ADULT; CARCINOMA, BASAL CELL; CELL PROLIFERATION; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; NEOPLASM PROTEINS; ODONTOGENIC TUMORS; RECEPTORS, NEUROKININ-1; SUBSTANCE P;

EID: 56549097852     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2008.02.010     Document Type: Article

References (47)

1. Shear M., and Speight P.M. Cysts of the oral and maxillofacial regions. 4th ed. (2007), Blackwell Munksgaard, Oxford, Ames, Iowa
2. Browne R.M. The odontogenic keratocyst. Histological features and their correlations with clinical behaviour. Brit Dent J 131 (1971) 249-259
3. Toller P.A. Autoradiography of explants from odontogenic cysts. Brit Dent J 131 (1971) 57-61
4. Matthews J.B., Mason G.I., and Browne R.M. Epithelial cell markers and proliferating cells in odontogenic jaw cysts. J Pathol 156 (1988) 283-290
5. Li T., Browne R.M., and Matthews J.B. Quantification of PCNA+ cells within odontogenic jaw cyst epithelium. J Oral Pathol Med 23 (1994) 184-189
6. Li T.J., Browne R.M., and Matthews J.B. Expression of epidermal growth factor receptors by odontogenic jaw cysts. Virchows Arch A Pathol Anat Histopathol 432 (1993) 137-144
7. Philipsen H.P. Keratocystic odontogenic tumour. In: Barnes L., Evenson J.W., Reichart P., and Sidransky D. (Eds). Pathology & genetics. Head and neck tumours (2005), IARC Press, Lyon 306-307
8. Lo Muzio L., Staibano S., Pannone G., Bucci P., Nocini P.F., Bucci E., et al. Expression of cell cycle and apoptosis-related proteins in sporadic odontogenic keratocyst and odontogenic keratocyst associated with the nevoid basal cell carcinoma syndrome. J Dent Res 78 (1999) 1345-1353
9. Levanat S., Gorlin R.J., Fallet S., Jonson D.R., Fantasia J.E., and Bale A.E. A two-hit model for developmental defects in Gorlin syndrome. Nature Genet 12 (1996) 85-87
10. Lench N.J., High A.S., Markham A.F., Hume W.J., and Robinson P.A. Investigation of chromosome 9q22.3-q31 DNA marker loss in odontogenic keratocyst. Eur J Cancer B Oral Oncol 32B (1996) 202-206
11. Barreto D.C., Gomez R.S., Bale A.E., Boson W.L., and De Marco L. PTCH gene mutations in odontogenic keratocyst. J Dent Res 79 (2000) 1418-1422
12. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 2. Proliferation and genetic studies. Oral Oncol 38 (2002) 323-331
13. Li T.J., Browne R.M., Prime S.S., Paterson I.C., and Matthews J.B. p53 Expression in odontogenic keratocyst epithelium. J Oral Pathol Med 25 (1996) 245-255
14. Piattelli A., Fioroni M., Santinelli A., and Rubini C. p53 Protein expression in odontogenic cysts. J Endod 27 (2001) 459-461
15. Li T.J., Browne R.M., Prime S.S., and Matthews J.B. Epithelial cell proliferation in odontogenic keratocysts: a comparative immunocytochemical study of Ki67 in simple, recurrent and basal cell naevus syndrome (BCNS)-associated lesions. J Oral Pathol Med 24 (1995) 221-226
16. Farndon P.A., Del Mastro R.G., Evans D.G., and Kilpatrick M.W. Location of gene for Gorlin syndrome. Lancet 339 (1992) 581-582
17. Heikinheimo K., Jee K.J., Morgan P.R., Nagy B., Happonen R.P., Knuutila S., et al. Gene expression profiling of odontogenic keratocyst. J Oral Pathol Med 33 (2004) 462
18. Esteban F., Muñoz M., Gonzalez-Moles M.A., and Rosso M. A role for substance P in cancer promotion and progression: a mechanism to counteract intracellular death signals following oncogen activation or DNA damage. Cancer Metastasis Rev 25 (2006) 137-145
19. Muñoz M., Rosso M., Coveñas R., Montero I., Gonzalez-Moles M.A., and Robles M.J. Neurokinin-1 receptors located in human retinoblastoma cell lines: antitumor action of its antagonist, L-732,138. Invest Ophthalmol Vis Sci 48 (2007) 2775-2781
20. Muñoz M, Rosso M, Aguilar FJ, Gonzalez-Moles MA, Redondo M, Esteban F. NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line Hep-2. Invest New Drugs 2007. doi:10.1007/s10637-007-9087-y.
21. DeVane C.L. Substance P: a new era, a new role. Pharmacotherapy 21 9 (2001) 1061-1069
22. Manthy P.W. Substance P and the inflammatory and immune response. Ann NY Acad Sci 632 (1991) 263-271
23. Harrison S., and Geppetti P. Substance P. Int J Biochem Cell Biol 33 (2001) 555-576
24. Culman J., and Unger T. Central tachykinins: mediators of defence reaction and stress reactions. Can J Physiol Pharmacol 73 7 (1995) 885-891
25. De Felipe C., Herrero J.F., O'Brien J.A., Palmer J.A., Doyle C.A., Smith A.J., et al. Altered nociception, analgesia and agresión in mice lacking the receptor for substance P. Nature 392 6674 (1998) 394-397
26. Horstman S., Kahle P.J., and Borasio G.D. Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro. J Neurosci Res 52 (1998) 483-490
27. Xia Z., Dickens M., Raingeaud J., Davis R.J., and Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270 (1995) 1326-1331
28. Koon H.W., Zhao D., Na X., Moyer M.P., and Pothoulakis C. Metalloproteinases and transforming growth factor-α mediate substance p-induced mitogen-activated protein kinase activation and proliferation in human colonocytes. J Biol Chem 279 (2004) 45519-45527
29. Coveñas R., Martin F., Salinas P., Rivada E., Smith V., Aguilar L.A., et al. An immunocytochemical mapping of methionine-enkephalin-Arg(6)-Gly(7)-Leu(8) in the human brainstem. Neuroscience 128 (2004) 843-859
30. Schulz S., Stumm R., Röcken C., Mawrin C., and Schulz S. Immunolocalization of full-length NK1 tachykinin receptors in human tumors. J Histochem Cytochem 54 (2006) 1015-1020
31. Weinstock J.V., Blum A., and Walden T. Eosinophils from granulomas in murine Schistosomiasis mansoni produce SP. J Immunol 141 (1998) 961-966
32. Cook G.A., Elliot D., Metwali A., Blu A.M., Sandor M., Lynch R., et al. Molecular evidence that granuloma T lymphocytes in murine Schistosomiasis mansoni express an authentic SP (NK1) receptor. Immunology 152 (1994) 1830-1835
33. Muñoz M., Rosso M., Perez A., Coveñas R., Rosso R., Zamarriego C., et al. Antitumoral action of the neurokinin-1-receptor antagonist L-733,060 and mitogenic action of substance P on human retinoblastoma cell lines. Invest Ophthalmol Vis Sci 46 (2005) 2567-2570
34. Payan D.G., Brewster D.R., and Goetzl E.J. Specific stimulation of human T lymphocytes by substance P. J Immunol 131 (1983) 1613-1615
35. Nilsson J., von Euler A.M., and Dalsgaard C.J. Stimulation of connective tissue cell growth by substance P and substance K. Nature 315 (1985) 61-63
36. Lotz M., Carson D.A., and Vaughan J.H. Substance P activation rheumatoid synoviocytes: neural pathway in pathogenesis of arthritis. Science 235 (1987) 893-895
37. Ziche M., Morbidelli L., Pacini Dolara P., and Maggi C.A. NK1-receptors mediate the proliferative response of human fibroblasts to tachykinins. Brit J Pharmacol 100 (1990) 11-14
38. Luo W., Sharif T.R., and Sharif M. Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signalling pathway. Cancer Res 56 (1996) 4983-4991
39. Muñoz M., Pérez A., Rosso M., Zamariego C., and Rosso R. Antitumoral action of NK1 receptor antagonist L-733,060 on human melanoma cell lines. Melanoma Res 14 (2004) 183-188
40. Palma C., Nardelli F., Manzini S., and Maggi C.A. Substance P activates responses correlated with tumour growth in human glioma cells line bearing tachykinin NK1 receptors. Brit J Cancer 79 (1999) 236-243
41. Sharif T.R., Luo W., Houghron P.J., and Sharif M. Substance K peptide induces mitogenesis by activating the mitogen-activated protein kinase signalling pathway through the substance P receptor (NK-1 subtype) in human astrocytoma. Cell Pharmacol 3 (1996) 441-449
42. Muñoz M., Rosso M., Pérez A., Coveñas R., Rosso R., Zamariego C., et al. The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines. Neuropeptides 39 4 (2005) 427-432
43. Gonzalez-Moles M.A., Mosqueda-Taylor A., Delgado-Rodriguez M., Martinez-Mata G., Gil-Montoya J.A., Diaz-Franco M.A., et al. Analysis of p53 protein by PAb240, Ki-67 expression and human papillomavirus DNA detection in different types of odontogenic keratocyst. Anticancer Res 26 (2006) 175-182
44. Rud J., and Pindborg J.J. Odontogenic keratocysts: a follow-up study of 21 cases. J Oral Surg 27 (1969) 323-330
45. Brannon R.B. The odontogenic keratocyst. A clinicopathologic study of 312 cases. Part II. Histologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 43 (1977) 233-255
46. Muñoz M., Perez A., Coveñas R., Rosso M., and Castro E. Antitumoural action of L-733,060 on neuroblastoma and glioma cell lines. Arch Ital Biol 142 (2004) 105-112
47. Reeve J.G., and Bleehen N.M. [D-Arg1, D-Phe5, D-Trp7,9, Leu11] substance P induces apoptosis in lung cancer cell lines in vitro. Biochem Biophys Res Com 199 (1994) 1313-1319