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Volumn 12, Issue 6, 2014, Pages 788-800

Myogenic tone as a therapeutic target for ischemic stroke

Author keywords

Cerebral blow flow; Circulating factors; Ischemic stroke; Middle cerebral arteries; Myogenic response; Parenchymal arterioles

Indexed keywords

ALTEPLASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; F ACTIN; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; MIFEPRISTONE; PEROXYNITRITE; PROTEIN KINASE C; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VOLTAGE GATED CALCIUM CHANNEL; NITRIC OXIDE; VASODILATOR AGENT;

EID: 84923231084     PISSN: 15701611     EISSN: 18756212     Source Type: Journal    
DOI: 10.2174/15701611113116660155     Document Type: Article
Times cited : (17)

References (153)
  • 1
    • 0025823740 scopus 로고
    • Effect of recirculation on exacerbation of ischemic vascular lesions in rat brain
    • Nishigaya K, Yoshida Y, Sasuga M, Nukui H, Ooneda G. Effect of recirculation on exacerbation of ischemic vascular lesions in rat brain. Stroke 1991; 22: 635-42.
    • (1991) Stroke , vol.22 , pp. 635-642
    • Nishigaya, K.1    Yoshida, Y.2    Sasuga, M.3    Nukui, H.4    Ooneda, G.5
  • 2
    • 0031026457 scopus 로고    scopus 로고
    • Reperfusion decreases myogenic reactivity and alters middle cerebral artery function after focal cerebral ischemia in rats
    • Cipolla MJ, McCall AL, Lessov N, Porter JM. Reperfusion decreases myogenic reactivity and alters middle cerebral artery function after focal cerebral ischemia in rats. Stroke 1997; 28: 176-80.
    • (1997) Stroke , vol.28 , pp. 176-180
    • Cipolla, M.J.1    McCall, A.L.2    Lessov, N.3    Porter, J.M.4
  • 3
    • 0020959273 scopus 로고
    • Local cerebral blood flow in the recovery period following complete cerebral ischemia in the rat
    • Kagstrom E, Smith ML, Siesjo BK. Local cerebral blood flow in the recovery period following complete cerebral ischemia in the rat. J Cereb Blood Flow Metab 1983; 3: 170-82.
    • (1983) J Cereb Blood Flow Metab , vol.3 , pp. 170-182
    • Kagstrom, E.1    Smith, M.L.2    Siesjo, B.K.3
  • 4
    • 0030985753 scopus 로고    scopus 로고
    • Cerebral cortex blood flow and vascular smooth muscle contractility in a rat model of ischemia: A correlative laser Doppler flowmetric and scanning electron microscopic study
    • Takahashi A, Park HK, Melgar MA, et al. Cerebral cortex blood flow and vascular smooth muscle contractility in a rat model of ischemia: a correlative laser Doppler flowmetric and scanning electron microscopic study. Acta Neuropathol 1997; 93: 354-68.
    • (1997) Acta Neuropathol , vol.93 , pp. 354-368
    • Takahashi, A.1    Park, H.K.2    Melgar, M.A.3
  • 5
    • 0026782517 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment
    • Siesjo BK. Pathophysiology and treatment of focal cerebral ischemia. Part II: Mechanisms of damage and treatment. J Neurosurg 1992; 77: 337-54.
    • (1992) J Neurosurg , vol.77 , pp. 337-354
    • Siesjo, B.K.1
  • 6
    • 0026777223 scopus 로고
    • Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology
    • Siesjo BK. Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. J Neurosurg 1992; 77: 169-84.
    • (1992) J Neurosurg , vol.77 , pp. 169-184
    • Siesjo, B.K.1
  • 7
    • 0026746208 scopus 로고
    • Pial vessel caliber and cerebral blood flow become dissociated during ischemia-reperfusion in cats
    • Tasdemiroglu E, Macfarlane R, Wei EP, Kontos HA, Moskowitz MA. Pial vessel caliber and cerebral blood flow become dissociated during ischemia-reperfusion in cats. Am J Physiol 1992; 263: H533-6.
    • (1992) Am J Physiol , vol.263 , pp. H533-H556
    • Tasdemiroglu, E.1    Macfarlane, R.2    Wei, E.P.3    Kontos, H.A.4    Moskowitz, M.A.5
  • 9
    • 0026857081 scopus 로고
    • Hypertension and the brain. The National High Blood Pressure Education Program
    • Phillips SJ, Whisnant JP. Hypertension and the brain. The National High Blood Pressure Education Program. Arch Intern Med 1992; 152: 938-45.
    • (1992) Arch Intern Med , vol.152 , pp. 938-945
    • Phillips, S.J.1    Whisnant, J.P.2
  • 10
    • 0024376584 scopus 로고
    • Myogenic mechanisms in the cerebral circulation
    • S61-4; discussion S5
    • Faraci FM, Baumbach GL, Heistad DD. Myogenic mechanisms in the cerebral circulation. J Hypertens Suppl 1989; 7: S61-4; discussion S5.
    • (1989) J Hypertens , pp. 7
    • Faraci, F.M.1    Baumbach, G.L.2    Heistad, D.D.3
  • 11
    • 0025097985 scopus 로고
    • Regulation of large cerebral arteries and cerebral microvascular pressure
    • Faraci FM, Heistad DD. Regulation of large cerebral arteries and cerebral microvascular pressure. Circ Res 1990; 66: 8-17.
    • (1990) Circ Res , vol.66 , pp. 8-17
    • Faraci, F.M.1    Heistad, D.D.2
  • 13
    • 0024387302 scopus 로고
    • Functional aspects of myogenic vascular control
    • S21-30; discussion S1
    • Mellander S. Functional aspects of myogenic vascular control. J Hypertens Suppl 1989; 7: S21-30; discussion S1.
    • (1989) J Hypertens , pp. 7
    • Mellander, S.1
  • 14
    • 0024404382 scopus 로고
    • Myogenic tone and reactivity: Definitions based on muscle physiology
    • S5-8; discussion S9
    • Johansson B. Myogenic tone and reactivity: definitions based on muscle physiology. J Hypertens Suppl 1989; 7: S5-8; discussion S9.
    • (1989) J Hypertens , pp. 7
    • Johansson, B.1
  • 17
    • 33845547792 scopus 로고    scopus 로고
    • Pathophysiology and therapy of experimental stroke
    • Hossmann KA. Pathophysiology and therapy of experimental stroke. Cell Mol Neurobiol 2006; 26: 1057-83.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 1057-1083
    • Hossmann, K.A.1
  • 18
    • 0042919302 scopus 로고    scopus 로고
    • Collateral circulation
    • Liebeskind DS. Collateral circulation. Stroke 2003; 34: 2279-84.
    • (2003) Stroke , vol.34 , pp. 2279-2284
    • Liebeskind, D.S.1
  • 19
    • 34247848042 scopus 로고    scopus 로고
    • Understanding blood flow: The other side of an acute arterial occlusion
    • Liebeskind DS. Understanding blood flow: the other side of an acute arterial occlusion. Int J Stroke 2007; 2: 118-20.
    • (2007) Int J Stroke , vol.2 , pp. 118-120
    • Liebeskind, D.S.1
  • 20
    • 0038076108 scopus 로고    scopus 로고
    • ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular acidification in vivo
    • Santa N, Kitazono T, Ago T, et al. ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular acidification in vivo. Stroke 2003; 34: 1276-80.
    • (2003) Stroke , vol.34 , pp. 1276-1280
    • Santa, N.1    Kitazono, T.2    Ago, T.3
  • 21
    • 0018729531 scopus 로고
    • Brain adenosine production in the rat during 60 seconds of ischemia
    • Winn HR, Rubio R, Berne RM. Brain adenosine production in the rat during 60 seconds of ischemia. Circ Res 1979; 45: 486-92.
    • (1979) Circ Res , vol.45 , pp. 486-492
    • Winn, H.R.1    Rubio, R.2    Berne, R.M.3
  • 22
    • 33644649803 scopus 로고    scopus 로고
    • Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease
    • Girouard H, Iadecola C. Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease. J Appl Physiol 2006; 100: 328-35.
    • (2006) J Appl Physiol , vol.100 , pp. 328-335
    • Girouard, H.1    Iadecola, C.2
  • 23
    • 0027982679 scopus 로고
    • Viability thresholds and the penumbra of focal ischemia
    • Hossmann KA. Viability thresholds and the penumbra of focal ischemia. Ann Neurol 1994; 36: 557-65.
    • (1994) Ann Neurol , vol.36 , pp. 557-565
    • Hossmann, K.A.1
  • 24
    • 0023492685 scopus 로고
    • The cerebral ischemic penumbra
    • Hakim AM. The cerebral ischemic penumbra. Can J Neurol Sci 1987; 14: 557-9.
    • (1987) Can J Neurol Sci , vol.14 , pp. 557-559
    • Hakim, A.M.1
  • 25
    • 0028811177 scopus 로고
    • Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: The relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances
    • Hoehn-Berlage M, Norris DG, Kohno K, Mies G, Leibfritz D, Hossmann KA. Evolution of regional changes in apparent diffusion coefficient during focal ischemia of rat brain: the relationship of quantitative diffusion NMR imaging to reduction in cerebral blood flow and metabolic disturbances. J Cereb Blood Flow Metab 1995; 15: 1002-11.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 1002-1011
    • Hoehn-Berlage, M.1    Norris, D.G.2    Kohno, K.3    Mies, G.4    Leibfritz, D.5    Hossmann, K.A.6
  • 26
    • 0021303937 scopus 로고
    • Characteristics of reactive hyperemia in the cerebral circulation
    • Gourley JK, Heistad DD. Characteristics of reactive hyperemia in the cerebral circulation. Am J Physiol 1984; 246: H52-8.
    • (1984) Am J Physiol , vol.246 , pp. H52-H88
    • Gourley, J.K.1    Heistad, D.D.2
  • 27
    • 0015042003 scopus 로고
    • Cerebral ischemia and reactive hyperemia. Studies of cortical blood flow and microcirculation before, during, and after temporary occlusion of middle cerebral artery of squirrel monkeys
    • Sundt TM, Jr., Waltz AG. Cerebral ischemia and reactive hyperemia. Studies of cortical blood flow and microcirculation before, during, and after temporary occlusion of middle cerebral artery of squirrel monkeys. Circ Res 1971; 28: 426-33.
    • (1971) Circ Res , vol.28 , pp. 426-433
    • Sundt, T.M.1    Waltz, A.G.2
  • 28
    • 0017735552 scopus 로고
    • Relationships among intracranial pressure, blood pressure, and superficial cerebral vasculature after experimental occlusion of one middle cerebral artery
    • Hayakawa T, Waltz AG, Hansen T. Relationships among intracranial pressure, blood pressure, and superficial cerebral vasculature after experimental occlusion of one middle cerebral artery. Stroke 1977; 8: 426-32.
    • (1977) Stroke , vol.8 , pp. 426-432
    • Hayakawa, T.1    Waltz, A.G.2    Hansen, T.3
  • 29
    • 0031202316 scopus 로고    scopus 로고
    • Reperfusion of the brain after global ischemia: Hemodynamic disturbances
    • discussion 2-3
    • Hossmann KA. Reperfusion of the brain after global ischemia: hemodynamic disturbances. Shock 1997; 8: 95-101; discussion 2-3.
    • (1997) Shock , vol.8 , pp. 95-101
    • Hossmann, K.A.1
  • 30
    • 0024828413 scopus 로고
    • Effects of ischemia on brain blood flow and oxygen consumption of newborn pigs
    • Leffler CW, Busija DW, Mirro R, Armstead WM, Beasley DG. Effects of ischemia on brain blood flow and oxygen consumption of newborn pigs. Am J Physiol 1989; 257: H1917-26.
    • (1989) Am J Physiol , vol.257 , pp. H1917-H18026
    • Leffler, C.W.1    Busija, D.W.2    Mirro, R.3    Armstead, W.M.4    Beasley, D.G.5
  • 31
    • 1842578299 scopus 로고    scopus 로고
    • Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy
    • Hauck EF, Apostel S, Hoffmann JF, Heimann A, Kempski O. Capillary flow and diameter changes during reperfusion after global cerebral ischemia studied by intravital video microscopy. J Cereb Blood Flow Metab 2004; 24: 383-91.
    • (2004) J Cereb Blood Flow Metab , vol.24 , pp. 383-391
    • Hauck, E.F.1    Apostel, S.2    Hoffmann, J.F.3    Heimann, A.4    Kempski, O.5
  • 32
    • 0016790028 scopus 로고
    • Microcirculatory obstruction in focal cerebral ischemia. Relationship to neuronal alterations
    • Little JR, Kerr FW, Sundt TM, Jr. Microcirculatory obstruction in focal cerebral ischemia. Relationship to neuronal alterations. Mayo Clin Proc 1975; 50: 264-70.
    • (1975) Mayo Clin Proc , vol.50 , pp. 264-270
    • Little, J.R.1    Kerr, F.W.2    Sundt, T.M.3
  • 33
    • 0025947863 scopus 로고
    • Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons
    • del Zoppo GJ, Schmid-Schonbein GW, Mori E, Copeland BR, Chang CM. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke 1991; 22: 1276-83.
    • (1991) Stroke , vol.22 , pp. 1276-1283
    • Del Zoppo, G.J.1    Schmid-Schonbein, G.W.2    Mori, E.3    Copeland, B.R.4    Chang, C.M.5
  • 34
    • 0022653970 scopus 로고
    • Polymorphonuclear leukocyte accumulation in brain regions with low blood flow during the early postischemic period
    • Hallenbeck JM, Dutka AJ, Tanishima T, et al. Polymorphonuclear leukocyte accumulation in brain regions with low blood flow during the early postischemic period. Stroke 1986; 17: 246-53.
    • (1986) Stroke , vol.17 , pp. 246-253
    • Hallenbeck, J.M.1    Dutka, A.J.2    Tanishima, T.3
  • 35
    • 69949172891 scopus 로고    scopus 로고
    • Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
    • Yemisci M, Gursoy-Ozdemir Y, Vural A, Can A, Topalkara K, Dalkara T. Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat Med 2009; 15: 1031-7.
    • (2009) Nat Med , vol.15 , pp. 1031-1037
    • Yemisci, M.1    Gursoy-Ozdemir, Y.2    Vural, A.3    Can, A.4    Topalkara, K.5    Dalkara, T.6
  • 36
    • 0030856804 scopus 로고    scopus 로고
    • Reperfusion injury: Demonstration of brain damage produced by reperfusion after transient focal ischemia in rats
    • Aronowski J, Strong R, Grotta JC. Reperfusion injury: demonstration of brain damage produced by reperfusion after transient focal ischemia in rats. J Cereb Blood Flow Metab 1997; 17: 1048-56.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 1048-1056
    • Aronowski, J.1    Strong, R.2    Grotta, J.C.3
  • 37
    • 84944486665 scopus 로고
    • On the local reactions of the arterial wall to changes of internal pressure
    • Bayliss WM. On the local reactions of the arterial wall to changes of internal pressure. J Physiol 1902; 28: 220-31.
    • (1902) J Physiol , vol.28 , pp. 220-231
    • Bayliss, W.M.1
  • 38
    • 0021668482 scopus 로고
    • Factors involved in the physiological regulation of the cerebral circulation
    • Busija DW, Heistad DD. Factors involved in the physiological regulation of the cerebral circulation. Rev Physiol Biochem Pharmacol 1984; 101: 161-211.
    • (1984) Rev Physiol Biochem Pharmacol , vol.101 , pp. 161-211
    • Busija, D.W.1    Heistad, D.D.2
  • 39
    • 21644457637 scopus 로고    scopus 로고
    • Alphavbeta3-and alpha5beta1-integrin blockade inhibits myogenic constriction of skeletal muscle resistance arterioles
    • Martinez-Lemus LA, Crow T, Davis MJ, Meininger GA. alphavbeta3-and alpha5beta1-integrin blockade inhibits myogenic constriction of skeletal muscle resistance arterioles. Am J Physiol Heart Circ Physiol 2005; 289: H322-9.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. H322-H349
    • Martinez-Lemus, L.A.1    Crow, T.2    Davis, M.J.3    Meininger, G.A.4
  • 41
    • 0036889937 scopus 로고    scopus 로고
    • Myogenic tone, reactivity, and forced dilatation: A three-phase model of in vitro arterial myogenic behavior
    • Osol G, Brekke JF, McElroy-Yaggy K, Gokina NI. Myogenic tone, reactivity, and forced dilatation: a three-phase model of in vitro arterial myogenic behavior. Am J Physiol Heart Circ Physiol 2002; 283: H2260-7.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H2260-H2277
    • Osol, G.1    Brekke, J.F.2    McElroy-Yaggy, K.3    Gokina, N.I.4
  • 42
    • 0031781521 scopus 로고    scopus 로고
    • Vascular smooth muscle actin cytoskeleton in cerebral artery forced dilatation
    • Cipolla MJ, Osol G. Vascular smooth muscle actin cytoskeleton in cerebral artery forced dilatation. Stroke 1998; 29: 1223-8.
    • (1998) Stroke , vol.29 , pp. 1223-1228
    • Cipolla, M.J.1    Osol, G.2
  • 43
    • 0019499710 scopus 로고
    • Focal cerebral hyperemia in acute stroke. Incidence, pathophysiology and clinical significance
    • Olsen TS, Larsen B, Skriver EB, Herning M, Enevoldsen E, Lassen NA. Focal cerebral hyperemia in acute stroke. Incidence, pathophysiology and clinical significance. Stroke 1981; 12: 598-607.
    • (1981) Stroke , vol.12 , pp. 598-607
    • Olsen, T.S.1    Larsen, B.2    Skriver, E.B.3    Herning, M.4    Enevoldsen, E.5    Lassen, N.A.6
  • 44
    • 0015411733 scopus 로고
    • The upper limit of autoregulation of cerebral blood flow--on the pathogenesis of hypertensive encepholopathy
    • Lassen NA, Agnoli A. The upper limit of autoregulation of cerebral blood flow--on the pathogenesis of hypertensive encepholopathy. Scand J Clin Lab Invest 1972; 30: 113-6.
    • (1972) Scand J Clin Lab Invest , vol.30 , pp. 113-116
    • Lassen, N.A.1    Agnoli, A.2
  • 45
    • 33846415816 scopus 로고    scopus 로고
    • Cerebral blood flow autoregulation and edema formation during pregnancy in anesthetized rats
    • Euser AG, Cipolla MJ. Cerebral blood flow autoregulation and edema formation during pregnancy in anesthetized rats. Hypertension 2007; 49: 334-40.
    • (2007) Hypertension , vol.49 , pp. 334-340
    • Euser, A.G.1    Cipolla, M.J.2
  • 46
    • 0014718721 scopus 로고
    • The effect of acute arterial hypertension on the blood-brain barrier to protein tracers
    • Johansson B, Li CL, Olsson Y, Klatzo I. The effect of acute arterial hypertension on the blood-brain barrier to protein tracers. Acta Neuropathol 1970; 16: 117-24.
    • (1970) Acta Neuropathol , vol.16 , pp. 117-124
    • Johansson, B.1    Li, C.L.2    Olsson, Y.3    Klatzo, I.4
  • 47
    • 0034934959 scopus 로고    scopus 로고
    • Threshold duration of ischemia for myogenic tone in middle cerebral arteries: Effect on vascular smooth muscle actin
    • Cipolla MJ, Lessov N, Hammer ES, Curry AB. Threshold duration of ischemia for myogenic tone in middle cerebral arteries: effect on vascular smooth muscle actin. Stroke 2001; 32: 1658-64.
    • (2001) Stroke , vol.32 , pp. 1658-1664
    • Cipolla, M.J.1    Lessov, N.2    Hammer, E.S.3    Curry, A.B.4
  • 48
    • 0036328004 scopus 로고    scopus 로고
    • Middle cerebral artery function after stroke: The threshold duration of reperfusion for myogenic activity
    • Cipolla MJ, Curry AB. Middle cerebral artery function after stroke: the threshold duration of reperfusion for myogenic activity. Stroke 2002; 33: 2094-9.
    • (2002) Stroke , vol.33 , pp. 2094-2099
    • Cipolla, M.J.1    Curry, A.B.2
  • 49
    • 65249129115 scopus 로고    scopus 로고
    • SKCa and IKCa Channels, myogenic tone, and vasodilator responses in middle cerebral arteries and parenchymal arterioles: Effect of ischemia and reperfusion
    • Cipolla MJ, Smith J, Kohlmeyer MM, Godfrey JA. SKCa and IKCa Channels, myogenic tone, and vasodilator responses in middle cerebral arteries and parenchymal arterioles: effect of ischemia and reperfusion. Stroke 2009; 40: 1451-7.
    • (2009) Stroke , vol.40 , pp. 1451-1457
    • Cipolla, M.J.1    Smith, J.2    Kohlmeyer, M.M.3    Godfrey, J.A.4
  • 50
    • 49349103593 scopus 로고    scopus 로고
    • Reactivity of brain parenchymal arterioles after ischemia and reperfusion
    • Cipolla MJ, Bullinger LV. Reactivity of brain parenchymal arterioles after ischemia and reperfusion. Microcirculation 2008; 15: 495-501.
    • (2008) Microcirculation , vol.15 , pp. 495-501
    • Cipolla, M.J.1    Bullinger, L.V.2
  • 51
    • 63949087753 scopus 로고    scopus 로고
    • Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke
    • Shih AY, Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D. Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. J Cereb Blood Flow Metab 2009; 29: 738-51.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 738-751
    • Shih, A.Y.1    Friedman, B.2    Drew, P.J.3    Tsai, P.S.4    Lyden, P.D.5    Kleinfeld, D.6
  • 52
    • 38849184196 scopus 로고    scopus 로고
    • The emerging role of Ca2+ sensitivity regulation in promoting myogenic vasoconstriction
    • Schubert R, Lidington D, Bolz SS. The emerging role of Ca2+ sensitivity regulation in promoting myogenic vasoconstriction. Cardiovasc Res 2008; 77: 8-18.
    • (2008) Cardiovasc Res , vol.77 , pp. 8-18
    • Schubert, R.1    Lidington, D.2    Bolz, S.S.3
  • 53
    • 0031037080 scopus 로고    scopus 로고
    • Myogenic contraction by modulation of voltage-dependent calcium currents in isolated rat cerebral arteries
    • McCarron JG, Crichton CA, Langton PD, MacKenzie A, Smith GL. Myogenic contraction by modulation of voltage-dependent calcium currents in isolated rat cerebral arteries. J Physiol 1997; 498(Pt 2): 371-9.
    • (1997) J Physiol , vol.498 , Issue.2 , pp. 371-379
    • McCarron, J.G.1    Crichton, C.A.2    Langton, P.D.3    Mackenzie, A.4    Smith, G.L.5
  • 54
    • 0032055663 scopus 로고    scopus 로고
    • Regulation of arterial diameter and wall [Ca2+] in cerebral arteries of rat by membrane potential and intravascular pressure
    • Knot HJ, Nelson MT. Regulation of arterial diameter and wall [Ca2+] in cerebral arteries of rat by membrane potential and intravascular pressure. J Physiol 1998; 508(Pt 1): 199-209.
    • (1998) J Physiol , vol.508 , Issue.1 , pp. 199-209
    • Knot, H.J.1    Nelson, M.T.2
  • 55
    • 0027953620 scopus 로고
    • Membrane stretch directly activates large conductance Ca(2+)-activated K+ channels in mesenteric artery smooth muscle cells
    • Dopico AM, Kirber MT, Singer JJ, Walsh JV, Jr. Membrane stretch directly activates large conductance Ca(2+)-activated K+ channels in mesenteric artery smooth muscle cells. Am J Hypertens 1994; 7: 82-9.
    • (1994) Am J Hypertens , vol.7 , pp. 82-89
    • Dopico, A.M.1    Kirber, M.T.2    Singer, J.J.3    Walsh, J.V.4
  • 56
    • 25444455580 scopus 로고    scopus 로고
    • Myogenic contraction in rat skeletal muscle arterioles: Smooth muscle membrane potential and Ca(2+) signaling
    • Kotecha N, Hill MA. Myogenic contraction in rat skeletal muscle arterioles: smooth muscle membrane potential and Ca(2+) signaling. Am J Physiol Heart Circ Physiol 2005; 289: H1326-34.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. H1326-H1354
    • Kotecha, N.1    Hill, M.A.2
  • 57
    • 67649390994 scopus 로고    scopus 로고
    • Therapeutic potential of pharmacologically targeting arteriolar myogenic tone
    • Hill MA, Meininger GA, Davis MJ, Laher I. Therapeutic potential of pharmacologically targeting arteriolar myogenic tone. Trends Pharmacol Sci 2009; 30: 363-74.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 363-374
    • Hill, M.A.1    Meininger, G.A.2    Davis, M.J.3    Laher, I.4
  • 58
    • 0037155047 scopus 로고    scopus 로고
    • Transient receptor potential channels regulate myogenic tone of resistance arteries
    • Welsh DG, Morielli AD, Nelson MT, Brayden JE. Transient receptor potential channels regulate myogenic tone of resistance arteries. Circ Res 2002; 90: 248-50.
    • (2002) Circ Res , vol.90 , pp. 248-250
    • Welsh, D.G.1    Morielli, A.D.2    Nelson, M.T.3    Brayden, J.E.4
  • 59
    • 7244239194 scopus 로고    scopus 로고
    • Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries
    • Earley S, Waldron BJ, Brayden JE. Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries. Circ Res 2004; 95: 922-9.
    • (2004) Circ Res , vol.95 , pp. 922-929
    • Earley, S.1    Waldron, B.J.2    Brayden, J.E.3
  • 60
    • 0030811810 scopus 로고    scopus 로고
    • Chloride channel blockers inhibit myogenic tone in rat cerebral arteries
    • Nelson MT, Conway MA, Knot HJ, Brayden JE. Chloride channel blockers inhibit myogenic tone in rat cerebral arteries. J Physiol 1997; 502(Pt 2): 259-64.
    • (1997) J Physiol , vol.502 , Issue.2 , pp. 259-264
    • Nelson, M.T.1    Conway, M.A.2    Knot, H.J.3    Brayden, J.E.4
  • 61
    • 0032217198 scopus 로고    scopus 로고
    • Ca2+ channels, ryanodine receptors and Ca(2+)-activated K+ channels: A functional unit for regulating arterial tone
    • Jaggar JH, Wellman GC, Heppner TJ, et al. Ca2+ channels, ryanodine receptors and Ca(2+)-activated K+ channels: a functional unit for regulating arterial tone. Acta Physiol Scand 1998; 164: 577-87.
    • (1998) Acta Physiol Scand , vol.164 , pp. 577-587
    • Jaggar, J.H.1    Wellman, G.C.2    Heppner, T.J.3
  • 63
    • 12344263554 scopus 로고    scopus 로고
    • Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction
    • Flavahan NA, Bailey SR, Flavahan WA, Mitra S, Flavahan S. Imaging remodeling of the actin cytoskeleton in vascular smooth muscle cells after mechanosensitive arteriolar constriction. Am J Physiol Heart Circ Physiol 2005; 288: H660-9.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. H660-H699
    • Flavahan, N.A.1    Bailey, S.R.2    Flavahan, W.A.3    Mitra, S.4    Flavahan, S.5
  • 64
    • 0036135875 scopus 로고    scopus 로고
    • Pressure-induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior
    • Cipolla MJ, Gokina NI, Osol G. Pressure-induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior. FASEB J 2002; 16: 72-6.
    • (2002) FASEB J , vol.16 , pp. 72-76
    • Cipolla, M.J.1    Gokina, N.I.2    Osol, G.3
  • 65
    • 0036889529 scopus 로고    scopus 로고
    • Effects of ischemia and myogenic activity on active and passive mechanical properties of rat cerebral arteries
    • Coulson RJ, Chesler NC, Vitullo L, Cipolla MJ. Effects of ischemia and myogenic activity on active and passive mechanical properties of rat cerebral arteries. Am J Physiol Heart Circ Physiol 2002; 283: H2268-75.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H2268-H2375
    • Coulson, R.J.1    Chesler, N.C.2    Vitullo, L.3    Cipolla, M.J.4
  • 66
    • 0034967004 scopus 로고    scopus 로고
    • INOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers
    • Banan A, Fields JZ, Zhang Y, Keshavarzian A. iNOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers. Am J Physiol Gastrointest Liver Physiol 2001; 280: G1234-46.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280 , pp. G1234-G1346
    • Banan, A.1    Fields, J.Z.2    Zhang, Y.3    Keshavarzian, A.4
  • 67
    • 0032941377 scopus 로고    scopus 로고
    • Ischemia activates actin depolymerizing factor: Role in proximal tubule microvillar actin alterations
    • Schwartz N, Hosford M, Sandoval RM, et al. Ischemia activates actin depolymerizing factor: role in proximal tubule microvillar actin alterations. Am J Physiol 1999; 276: F544-51.
    • (1999) Am J Physiol , vol.276 , pp. F544-F651
    • Schwartz, N.1    Hosford, M.2    Sandoval, R.M.3
  • 68
    • 34250806560 scopus 로고    scopus 로고
    • Increased oxidative stress during hyperglycemic cerebral ischemia
    • Bemeur C, Ste-Marie L, Montgomery J. Increased oxidative stress during hyperglycemic cerebral ischemia. Neurochem Int 2007; 50: 890-904.
    • (2007) Neurochem Int , vol.50 , pp. 890-904
    • Bemeur, C.1    Ste-Marie, L.2    Montgomery, J.3
  • 69
    • 33645082252 scopus 로고    scopus 로고
    • Peroxynitrite diminishes myogenic activity and is associated with decreased vascular smooth muscle F-actin in rat posterior cerebral arteries
    • Maneen MJ, Hannah R, Vitullo L, DeLance N, Cipolla MJ. Peroxynitrite diminishes myogenic activity and is associated with decreased vascular smooth muscle F-actin in rat posterior cerebral arteries. Stroke 2006; 37: 894-9.
    • (2006) Stroke , vol.37 , pp. 894-899
    • Maneen, M.J.1    Hannah, R.2    Vitullo, L.3    Delance, N.4    Cipolla, M.J.5
  • 70
    • 33846993419 scopus 로고    scopus 로고
    • Peroxynitrite diminishes myogenic tone in cerebral arteries: Role of nitrotyrosine and F-actin
    • Maneen MJ, Cipolla MJ. Peroxynitrite diminishes myogenic tone in cerebral arteries: role of nitrotyrosine and F-actin. Am J Physiol Heart Circ Physiol 2007; 292: H1042-50.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H1042-H1350
    • Maneen, M.J.1    Cipolla, M.J.2
  • 71
    • 0028008143 scopus 로고
    • Moderate hyperglycemia affects ischemic brain ATP levels but not intracellular pH
    • Hsu SS, Meno JR, Gronka R, Kushmerick M, Winn HR. Moderate hyperglycemia affects ischemic brain ATP levels but not intracellular pH. Am J Physiol 1994; 266: H258-62.
    • (1994) Am J Physiol , vol.266 , pp. H258-H462
    • Hsu, S.S.1    Meno, J.R.2    Gronka, R.3    Kushmerick, M.4    Winn, H.R.5
  • 72
    • 25144455054 scopus 로고    scopus 로고
    • Actin redistribution underlies the sparing effect of mild hypothermia on dendritic spine morphology after in vitro ischemia
    • Gisselsson LL, Matus A, Wieloch T. Actin redistribution underlies the sparing effect of mild hypothermia on dendritic spine morphology after in vitro ischemia. J Cereb Blood Flow Metab 2005; 25: 1346-55.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1346-1355
    • Gisselsson, L.L.1    Matus, A.2    Wieloch, T.3
  • 73
    • 23044515393 scopus 로고    scopus 로고
    • Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke
    • Miyata N, Seki T, Tanaka Y, et al. Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N'-hydroxyimido formamide], on hemorrhagic and ischemic stroke. J Pharmacol Exp Ther 2005; 314: 77-85.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 77-85
    • Miyata, N.1    Seki, T.2    Tanaka, Y.3
  • 74
    • 0031863253 scopus 로고    scopus 로고
    • Altered function of inward rectifier potassium channels in cerebrovascular smooth muscle after ischemia/reperfusion
    • Marrelli SP, Johnson TD, Khorovets A, Childres WF, Bryan RM, Jr. Altered function of inward rectifier potassium channels in cerebrovascular smooth muscle after ischemia/reperfusion. Stroke 1998; 29: 1469-74.
    • (1998) Stroke , vol.29 , pp. 1469-1474
    • Marrelli, S.P.1    Johnson, T.D.2    Khorovets, A.3    Childres, W.F.4    Bryan, R.M.5
  • 75
    • 0033396340 scopus 로고    scopus 로고
    • Relationship between inward rectifier potassium current impairment and brain injury after cerebral ischemia/reperfusion
    • Bastide M, Bordet R, Pu Q, Robin E, Puisieux F, Dupuis B. Relationship between inward rectifier potassium current impairment and brain injury after cerebral ischemia/reperfusion. J Cereb Blood Flow Metab 1999; 19: 1309-15.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 1309-1315
    • Bastide, M.1    Bordet, R.2    Pu, Q.3    Robin, E.4    Puisieux, F.5    Dupuis, B.6
  • 76
    • 0026026969 scopus 로고
    • Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats
    • Kawamura S, Shirasawa M, Fukasawa H, Yasui N. Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats. Stroke 1991; 22: 51-5.
    • (1991) Stroke , vol.22 , pp. 51-55
    • Kawamura, S.1    Shirasawa, M.2    Fukasawa, H.3    Yasui, N.4
  • 77
    • 0026101768 scopus 로고
    • Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats
    • Shiino A, Matsuda M, Susumu T, Handa J. Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. Surg Neurol 1991; 35: 105-10.
    • (1991) Surg Neurol , vol.35 , pp. 105-110
    • Shiino, A.1    Matsuda, M.2    Susumu, T.3    Handa, J.4
  • 79
    • 0026101746 scopus 로고
    • Modulates basal myogenic tone in resistance arteries from the cerebral circulation
    • Osol G, Laher I, Cipolla M. Protein kinase C modulates basal myogenic tone in resistance arteries from the cerebral circulation. Circ Res 1991; 68: 359-67.
    • (1991) Circ Res , vol.68 , pp. 359-367
    • Osol, G.1    Laher, I.2    Cipolla, M.3    Protein Kinase, C.4
  • 80
    • 0036889524 scopus 로고    scopus 로고
    • Pressure-dependent myogenic constriction of cerebral arteries occurs independently of voltage-dependent activation
    • Lagaud G, Gaudreault N, Moore ED, Van Breemen C, Laher I. Pressure-dependent myogenic constriction of cerebral arteries occurs independently of voltage-dependent activation. Am J Physiol Heart Circ Physiol 2002; 283: H2187-95.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H2187-H2395
    • Lagaud, G.1    Gaudreault, N.2    Moore, E.D.3    Van Breemen, C.4    Laher, I.5
  • 81
    • 0032571235 scopus 로고    scopus 로고
    • Regulatory mechanisms of calcium sensitization of contractile elements in smooth muscle
    • Hori M, Karaki H. Regulatory mechanisms of calcium sensitization of contractile elements in smooth muscle. Life Sci 1998; 62: 1629-33.
    • (1998) Life Sci , vol.62 , pp. 1629-1633
    • Hori, M.1    Karaki, H.2
  • 82
    • 0035838950 scopus 로고    scopus 로고
    • Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage
    • Satoh S, Utsunomiya T, Tsurui K, et al. Pharmacological profile of hydroxy fasudil as a selective rho kinase inhibitor on ischemic brain damage. Life Sci 2001; 69: 1441-53.
    • (2001) Life Sci , vol.69 , pp. 1441-1453
    • Satoh, S.1    Utsunomiya, T.2    Tsurui, K.3
  • 83
    • 33644685637 scopus 로고    scopus 로고
    • The role of protein kinase C in cerebral ischemic and reperfusion injury
    • Bright R, Mochly-Rosen D. The role of protein kinase C in cerebral ischemic and reperfusion injury. Stroke 2005; 36: 2781-90.
    • (2005) Stroke , vol.36 , pp. 2781-2790
    • Bright, R.1    Mochly-Rosen, D.2
  • 84
    • 0034909922 scopus 로고    scopus 로고
    • Protein kinase C and cerebral vasospasm
    • Laher I, Zhang JH. Protein kinase C and cerebral vasospasm. J Cereb Blood Flow Metab 2001; 21: 887-906.
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 887-906
    • Laher, I.1    Zhang, J.H.2
  • 85
    • 0033848417 scopus 로고    scopus 로고
    • The role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts
    • Maczewski M, Beresewicz A. The role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts. J Mol Cell Cardiol 2000; 32: 297-310.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 297-310
    • Maczewski, M.1    Beresewicz, A.2
  • 86
    • 0031893415 scopus 로고    scopus 로고
    • Regulation of the cerebral circulation: Role of endothelium and potassium channels
    • Faraci FM, Heistad DD. Regulation of the cerebral circulation: role of endothelium and potassium channels. Physiol Rev 1998; 78: 53-97.
    • (1998) Physiol Rev , vol.78 , pp. 53-97
    • Faraci, F.M.1    Heistad, D.D.2
  • 87
    • 0028118673 scopus 로고
    • Nitric oxide and the cerebral circulation
    • Faraci FM, Brian JE, Jr. Nitric oxide and the cerebral circulation. Stroke 1994; 25: 692-703.
    • (1994) Stroke , vol.25 , pp. 692-703
    • Faraci, F.M.1    Brian, J.E.2
  • 88
    • 0025883342 scopus 로고
    • Nitric oxide: Physiology, pathophysiology, and pharmacology
    • Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991; 43: 109-42.
    • (1991) Pharmacol Rev , vol.43 , pp. 109-142
    • Moncada, S.1    Palmer, R.M.2    Higgs, E.A.3
  • 89
    • 0024388901 scopus 로고
    • Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor
    • Tayeh MA, Marletta MA. Macrophage oxidation of L-arginine to nitric oxide, nitrite, and nitrate. Tetrahydrobiopterin is required as a cofactor. J Biol Chem 1989; 264: 19654-8.
    • (1989) J Biol Chem , vol.264 , pp. 19654-19658
    • Tayeh, M.A.1    Marletta, M.A.2
  • 90
    • 0037772382 scopus 로고    scopus 로고
    • Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase
    • Bauer PM, Fulton D, Boo YC, et al. Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase. J Biol Chem 2003; 278: 14841-9.
    • (2003) J Biol Chem , vol.278 , pp. 14841-14849
    • Bauer, P.M.1    Fulton, D.2    Boo, Y.C.3
  • 91
    • 0028329222 scopus 로고
    • The complex role of nitric oxide in the pathophysiology of focal cerebral ischemia
    • Dalkara T, Moskowitz MA. The complex role of nitric oxide in the pathophysiology of focal cerebral ischemia. Brain Pathol 1994; 4: 49-57.
    • (1994) Brain Pathol , vol.4 , pp. 49-57
    • Dalkara, T.1    Moskowitz, M.A.2
  • 92
    • 0029821693 scopus 로고    scopus 로고
    • Temporal correlation mapping analysis of the hemodynamic penumbra in mutant mice deficient in endothelial nitric oxide synthase gene expression
    • Lo EH, Hara H, Rogowska J, et al. Temporal correlation mapping analysis of the hemodynamic penumbra in mutant mice deficient in endothelial nitric oxide synthase gene expression. Stroke 1996; 27: 1381-5.
    • (1996) Stroke , vol.27 , pp. 1381-1385
    • Lo, E.H.1    Hara, H.2    Rogowska, J.3
  • 93
    • 0029780767 scopus 로고    scopus 로고
    • Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-Larginine
    • Huang Z, Huang PL, Ma J, et al. Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-Larginine. J Cereb Blood Flow Metab 1996; 16: 981-7.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 981-987
    • Huang, Z.1    Huang, P.L.2    Ma, J.3
  • 94
    • 0029936604 scopus 로고    scopus 로고
    • Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase
    • Panahian N, Yoshida T, Huang PL, et al. Attenuated hippocampal damage after global cerebral ischemia in mice mutant in neuronal nitric oxide synthase. Neuroscience 1996; 72: 343-54.
    • (1996) Neuroscience , vol.72 , pp. 343-354
    • Panahian, N.1    Yoshida, T.2    Huang, P.L.3
  • 95
    • 0028851010 scopus 로고
    • Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion
    • Zhang ZG, Chopp M, Bailey F, Malinski T. Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion. J Neurol Sci 1995; 128: 22-7.
    • (1995) J Neurol Sci , vol.128 , pp. 22-27
    • Zhang, Z.G.1    Chopp, M.2    Bailey, F.3    Malinski, T.4
  • 96
    • 0027314739 scopus 로고
    • Regulation of the cerebral microcirculation during neural activity: Is nitric oxide the missing link?
    • Iadecola C. Regulation of the cerebral microcirculation during neural activity: is nitric oxide the missing link? Trends Neurosci 1993; 16: 206-14.
    • (1993) Trends Neurosci , vol.16 , pp. 206-214
    • Iadecola, C.1
  • 97
    • 0028910754 scopus 로고
    • Nitric oxide is an antiadhesive molecule for leukocytes
    • Kanwar S, Kubes P. Nitric oxide is an antiadhesive molecule for leukocytes. New Horiz 1995; 3: 93-104.
    • (1995) New Horiz , vol.3 , pp. 93-104
    • Kanwar, S.1    Kubes, P.2
  • 98
    • 0036842344 scopus 로고    scopus 로고
    • Transient focal ischemia increases endothelial nitric oxide synthase in cerebral blood vessels
    • Veltkamp R, Rajapakse N, Robins G, Puskar M, Shimizu K, Busija D. Transient focal ischemia increases endothelial nitric oxide synthase in cerebral blood vessels. Stroke 2002; 33: 2704-10.
    • (2002) Stroke , vol.33 , pp. 2704-2710
    • Veltkamp, R.1    Rajapakse, N.2    Robins, G.3    Puskar, M.4    Shimizu, K.5    Busija, D.6
  • 99
    • 0034117546 scopus 로고    scopus 로고
    • Postischemic attenuation of cerebral artery reactivity is increased in the presence of tissue plasminogen activator
    • Cipolla MJ, Lessov N, Clark WM, Haley EC, Jr. Postischemic attenuation of cerebral artery reactivity is increased in the presence of tissue plasminogen activator. Stroke 2000; 31: 940-5.
    • (2000) Stroke , vol.31 , pp. 940-945
    • Cipolla, M.J.1    Lessov, N.2    Clark, W.M.3    Haley, E.C.4
  • 100
    • 0032951725 scopus 로고    scopus 로고
    • P2 purinoceptor-mediated dilations in the rat middle cerebral artery after ischemia-reperfusion
    • Marrelli SP, Khorovets A, Johnson TD, Childres WF, Bryan RM, Jr. P2 purinoceptor-mediated dilations in the rat middle cerebral artery after ischemia-reperfusion. Am J Physiol 1999; 276: H33-41.
    • (1999) Am J Physiol , vol.276 , pp. H33-H41
    • Marrelli, S.P.1    Khorovets, A.2    Johnson, T.D.3    Childres, W.F.4    Bryan, R.M.5
  • 101
    • 0023689452 scopus 로고
    • Responses of cerebral arteries after ischemia and reperfusion in cats
    • Mayhan WG, Amundsen SM, Faraci FM, Heistad DD. Responses of cerebral arteries after ischemia and reperfusion in cats. Am J Physiol 1988; 255: H879-84.
    • (1988) Am J Physiol , vol.255 , pp. H879-H984
    • Mayhan, W.G.1    Amundsen, S.M.2    Faraci, F.M.3    Heistad, D.D.4
  • 102
    • 0031034858 scopus 로고    scopus 로고
    • Selective impairment of response to acetylcholine after ischemia/reperfusion in mice
    • discussion 51-2
    • Rosenblum WI. Selective impairment of response to acetylcholine after ischemia/reperfusion in mice. Stroke 1997; 28: 448-51; discussion 51-2.
    • (1997) Stroke , vol.28 , pp. 448-451
    • Rosenblum, W.I.1
  • 104
    • 0032475865 scopus 로고    scopus 로고
    • Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem 1998; 273: 25804-8.
    • (1998) J Biol Chem , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 105
    • 0026584089 scopus 로고
    • Ca2+/calmodulindependent formation of hydrogen peroxide by brain nitric oxide synthase
    • Heinzel B, John M, Klatt P, Bohme E, Mayer B. Ca2+/calmodulindependent formation of hydrogen peroxide by brain nitric oxide synthase. Biochem J 1992; 281 (Pt 3): 627-30.
    • (1992) Biochem J , vol.281 , Issue.3 , pp. 627-630
    • Heinzel, B.1    John, M.2    Klatt, P.3    Bohme, E.4    Mayer, B.5
  • 106
    • 0026470180 scopus 로고
    • Generation of superoxide by purified brain nitric oxide synthase
    • Pou S, Pou WS, Bredt DS, Snyder SH, Rosen GM. Generation of superoxide by purified brain nitric oxide synthase. J Biol Chem 1992; 267: 24173-6.
    • (1992) J Biol Chem , vol.267 , pp. 24173-24176
    • Pou, S.1    Pou, W.S.2    Bredt, D.S.3    Snyder, S.H.4    Rosen, G.M.5
  • 107
    • 0034837885 scopus 로고    scopus 로고
    • Vascular endothelial dysfunction: Does tetrahydrobiopterin play a role?
    • Katusic ZS. Vascular endothelial dysfunction: does tetrahydrobiopterin play a role? Am J Physiol Heart Circ Physiol 2001; 281: H981-6.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281 , pp. H981-H1966
    • Katusic, Z.S.1
  • 108
    • 0028584148 scopus 로고
    • Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration
    • Beckman JS, Chen J, Crow JP, Ye YZ. Reactions of nitric oxide, superoxide and peroxynitrite with superoxide dismutase in neurodegeneration. Prog Brain Res 1994; 103: 371-80.
    • (1994) Prog Brain Res , vol.103 , pp. 371-380
    • Beckman, J.S.1    Chen, J.2    Crow, J.P.3    Ye, Y.Z.4
  • 109
    • 0033527413 scopus 로고    scopus 로고
    • Oxidation of tetrahydrobiopterin by peroxynitrite: Implications for vascular endothelial function
    • Milstien S, Katusic Z. Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function. Biochem Biophys Res Commun 1999; 263: 681-4.
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 681-684
    • Milstien, S.1    Katusic, Z.2
  • 110
    • 34250731849 scopus 로고    scopus 로고
    • Life history of eNOS: Partners and pathways
    • Dudzinski DM, Michel T. Life history of eNOS: partners and pathways. Cardiovasc Res 2007; 75: 247-60.
    • (2007) Cardiovasc Res , vol.75 , pp. 247-260
    • Dudzinski, D.M.1    Michel, T.2
  • 112
    • 55249112287 scopus 로고    scopus 로고
    • Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme
    • Chen CA, Druhan LJ, Varadharaj S, Chen YR, Zweier JL. Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme. J Biol Chem 2008; 283: 27038-47.
    • (2008) J Biol Chem , vol.283 , pp. 27038-27047
    • Chen, C.A.1    Druhan, L.J.2    Varadharaj, S.3    Chen, Y.R.4    Zweier, J.L.5
  • 113
    • 0141565369 scopus 로고    scopus 로고
    • Role of endothelial intermediate conductance KCa channels in cerebral EDHFmediated dilations
    • Marrelli SP, Eckmann MS, Hunte MS. Role of endothelial intermediate conductance KCa channels in cerebral EDHFmediated dilations. Am J Physiol Heart Circ Physiol 2003; 285: H1590-9.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. H1590-H1599
    • Marrelli, S.P.1    Eckmann, M.S.2    Hunte, M.S.3
  • 114
    • 33646707265 scopus 로고    scopus 로고
    • Evidence for involvement of both IKCa and SKCa channels in hyperpolarizing responses of the rat middle cerebral artery
    • McNeish AJ, Sandow SL, Neylon CB, Chen MX, Dora KA, Garland CJ. Evidence for involvement of both IKCa and SKCa channels in hyperpolarizing responses of the rat middle cerebral artery. Stroke 2006; 37: 1277-82.
    • (2006) Stroke , vol.37 , pp. 1277-1282
    • McNeish, A.J.1    Sandow, S.L.2    Neylon, C.B.3    Chen, M.X.4    Dora, K.A.5    Garland, C.J.6
  • 115
    • 45149098981 scopus 로고    scopus 로고
    • Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries
    • Dora KA, Gallagher NT, McNeish A, Garland CJ. Modulation of endothelial cell KCa3.1 channels during endothelium-derived hyperpolarizing factor signaling in mesenteric resistance arteries. Circ Res 2008; 102: 1247-55.
    • (2008) Circ Res , vol.102 , pp. 1247-1255
    • Dora, K.A.1    Gallagher, N.T.2    McNeish, A.3    Garland, C.J.4
  • 116
    • 0029912917 scopus 로고    scopus 로고
    • Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery
    • Zygmunt PM, Hogestatt ED. Role of potassium channels in endothelium-dependent relaxation resistant to nitroarginine in the rat hepatic artery. Br J Pharmacol 1996; 117: 1600-6.
    • (1996) Br J Pharmacol , vol.117 , pp. 1600-1606
    • Zygmunt, P.M.1    Hogestatt, E.D.2
  • 117
    • 33748345798 scopus 로고    scopus 로고
    • Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel
    • Si H, Heyken WT, Wolfle SE, et al. Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca2+-activated K+ channel. Circ Res 2006; 99: 537-44.
    • (2006) Circ Res , vol.99 , pp. 537-544
    • Si, H.1    Heyken, W.T.2    Wolfle, S.E.3
  • 118
    • 0032888198 scopus 로고    scopus 로고
    • Functional heterogeneity of endothelial P2 purinoceptors in the cerebrovascular tree of the rat
    • You J, Johnson TD, Marrelli SP, Bryan RM, Jr. Functional heterogeneity of endothelial P2 purinoceptors in the cerebrovascular tree of the rat. Am J Physiol 1999; 277: H893-900.
    • (1999) Am J Physiol , vol.277 , pp. H893-H900
    • You, J.1    Johnson, T.D.2    Marrelli, S.P.3    Bryan, R.M.4
  • 119
  • 120
    • 0036707497 scopus 로고    scopus 로고
    • Altered endothelial Ca2+ regulation after ischemia/reperfusion produces potentiated endothelium-derived hyperpolarizing factor-mediated dilations
    • Marrelli SP. Altered endothelial Ca2+ regulation after ischemia/reperfusion produces potentiated endothelium-derived hyperpolarizing factor-mediated dilations. Stroke 2002; 33: 2285-91.
    • (2002) Stroke , vol.33 , pp. 2285-2291
    • Marrelli, S.P.1
  • 121
    • 0027984808 scopus 로고
    • Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
    • Rubanyi GM, Polokoff MA. Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 1994; 46: 325-415.
    • (1994) Pharmacol Rev , vol.46 , pp. 325-415
    • Rubanyi, G.M.1    Polokoff, M.A.2
  • 122
    • 0028927025 scopus 로고
    • New developments in the understanding of cerebral vasoregulation and vasospasm: The endothelin-nitric oxide network
    • Ehrenreich H, Schilling L. New developments in the understanding of cerebral vasoregulation and vasospasm: the endothelin-nitric oxide network. Cleve Clin J Med 1995; 62: 105-16.
    • (1995) Cleve Clin J Med , vol.62 , pp. 105-116
    • Ehrenreich, H.1    Schilling, L.2
  • 124
    • 0028008827 scopus 로고
    • Endothelin levels increase in rat focal and global ischemia
    • Barone FC, Globus MY, Price WJ, et al. Endothelin levels increase in rat focal and global ischemia. J Cereb Blood Flow Metab 1994; 14: 337-42.
    • (1994) J Cereb Blood Flow Metab , vol.14 , pp. 337-342
    • Barone, F.C.1    Globus, M.Y.2    Price, W.J.3
  • 125
    • 0028228133 scopus 로고
    • Increased endothelin-1 in the rabbit model of middle cerebral artery occlusion
    • Bian LG, Zhang TX, Zhao WG, Shen JK, Yang GY. Increased endothelin-1 in the rabbit model of middle cerebral artery occlusion. Neurosci Lett 1994; 174: 47-50.
    • (1994) Neurosci Lett , vol.174 , pp. 47-50
    • Bian, L.G.1    Zhang, T.X.2    Zhao, W.G.3    Shen, J.K.4    Yang, G.Y.5
  • 126
    • 0027250204 scopus 로고
    • Characterization of receptors for endothelins in the perfused arterial and venous mesenteric vasculatures of the rat
    • D'Orleans-Juste P, Claing A, Warner TD, Yano M, Telemaque S. Characterization of receptors for endothelins in the perfused arterial and venous mesenteric vasculatures of the rat. Br J Pharmacol 1993; 110: 687-92.
    • (1993) Br J Pharmacol , vol.110 , pp. 687-692
    • D'orleans-Juste, P.1    Claing, A.2    Warner, T.D.3    Yano, M.4    Telemaque, S.5
  • 127
    • 0029112769 scopus 로고
    • Therapeutic effects of endothelin receptor antagonists in stroke
    • Barone FC, Willette RN, Yue TL, Feurestein G. Therapeutic effects of endothelin receptor antagonists in stroke. Neurol Res 1995; 17: 259-64.
    • (1995) Neurol Res , vol.17 , pp. 259-264
    • Barone, F.C.1    Willette, R.N.2    Yue, T.L.3    Feurestein, G.4
  • 128
    • 0032721538 scopus 로고    scopus 로고
    • Endothelin receptor antagonist preserves microvascular perfusion and reduces ischemic brain damage following permanent focal ischemia
    • Dawson DA, Sugano H, McCarron RM, Hallenbeck JM, Spatz M. Endothelin receptor antagonist preserves microvascular perfusion and reduces ischemic brain damage following permanent focal ischemia. Neurochem Res 1999; 24: 1499-505.
    • (1999) Neurochem Res , vol.24 , pp. 1499-1505
    • Dawson, D.A.1    Sugano, H.2    McCarron, R.M.3    Hallenbeck, J.M.4    Spatz, M.5
  • 129
    • 0034831353 scopus 로고    scopus 로고
    • Protective effect of endothelin type A receptor antagonist on brain edema and injury after transient middle cerebral artery occlusion in rats
    • Matsuo Y, Mihara S, Ninomiya M, Fujimoto M. Protective effect of endothelin type A receptor antagonist on brain edema and injury after transient middle cerebral artery occlusion in rats. Stroke 2001; 32: 2143-8.
    • (2001) Stroke , vol.32 , pp. 2143-2148
    • Matsuo, Y.1    Mihara, S.2    Ninomiya, M.3    Fujimoto, M.4
  • 130
    • 63449101376 scopus 로고    scopus 로고
    • Endothelial endothelin-1 overexpression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after transient middle cerebral artery occlusion
    • Leung JW, Chung SS, Chung SK. Endothelial endothelin-1 overexpression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after transient middle cerebral artery occlusion. Brain Res 2009; 1266: 121-9.
    • (2009) Brain Res , vol.1266 , pp. 121-129
    • Leung, J.W.1    Chung, S.S.2    Chung, S.K.3
  • 131
    • 0028987243 scopus 로고
    • Endothelins stimulate sodium uptake into rat brain capillary endothelial cells through endothelin A-like receptors
    • Kawai N, McCarron RM, Spatz M. Endothelins stimulate sodium uptake into rat brain capillary endothelial cells through endothelin A-like receptors. Neurosci Lett 1995; 190: 85-8.
    • (1995) Neurosci Lett , vol.190 , pp. 85-88
    • Kawai, N.1    McCarron, R.M.2    Spatz, M.3
  • 132
    • 0028190111 scopus 로고
    • Arachidonic acid release and permeability changes induced by endothelins in human cerebromicrovascular endothelium
    • Stanimirovic DB, Bertrand N, McCarron R, Uematsu S, Spatz M. Arachidonic acid release and permeability changes induced by endothelins in human cerebromicrovascular endothelium. Acta Neurochir Suppl (Wien) 1994; 60: 71-5.
    • (1994) Acta Neurochir Suppl (Wien) , vol.60 , pp. 71-75
    • Stanimirovic, D.B.1    Bertrand, N.2    McCarron, R.3    Uematsu, S.4    Spatz, M.5
  • 133
    • 70350521869 scopus 로고    scopus 로고
    • Geographic distribution of rt-PA utilization by hospital for acute ischemic stroke
    • Kleindorfer D, Xu Y, Moomaw CJ, Khatri P, Adeoye O, Hornung R. US geographic distribution of rt-PA utilization by hospital for acute ischemic stroke. Stroke 2009; 40: 3580-4.
    • (2009) Stroke , vol.40 , pp. 3580-3584
    • Kleindorfer, D.1    Xu, Y.2    Moomaw, C.J.3    Khatri, P.4    Adeoye, O.5    Hornung, R.6
  • 134
    • 0024239574 scopus 로고
    • Fatal ischaemic brain oedema after early thrombolysis with tissue plasminogen activator in acute stroke
    • Koudstaal PJ, Stibbe J, Vermeulen M. Fatal ischaemic brain oedema after early thrombolysis with tissue plasminogen activator in acute stroke. BMJ 1988; 297: 1571-4.
    • (1988) BMJ , vol.297 , pp. 1571-1574
    • Koudstaal, P.J.1    Stibbe, J.2    Vermeulen, M.3
  • 136
    • 77955850207 scopus 로고    scopus 로고
    • Inflammation After Stroke: Mechanisms and TherapeuticApproaches
    • Ahmad M, Graham SH. Inflammation After Stroke: Mechanisms and Therapeutic Approaches. Transl Stroke Res 2010; 1: 74-84.
    • (2010) Transl Stroke Res , vol.1 , pp. 74-84
    • Ahmad, M.1    Graham, S.H.2
  • 137
    • 0028220499 scopus 로고
    • Proinflammatory cytokines in serum of patients with acute cerebral ischemia: Kinetics of secretion and relation to the extent of brain damage and outcome of disease
    • Fassbender K, Rossol S, Kammer T, et al. Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease. J Neurol Sci 1994; 122: 135-9.
    • (1994) J Neurol Sci , vol.122 , pp. 135-139
    • Fassbender, K.1    Rossol, S.2    Kammer, T.3
  • 138
    • 0034949408 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha is increased in the cerebrospinal fluid and serum of ischaemic stroke patients and correlates with the volume of evolving brain infarct
    • Zaremba J, Skrobanski P, Losy J. Tumour necrosis factor-alpha is increased in the cerebrospinal fluid and serum of ischaemic stroke patients and correlates with the volume of evolving brain infarct. Biomed Pharmacother 2001; 55: 258-63.
    • (2001) Biomed Pharmacother , vol.55 , pp. 258-263
    • Zaremba, J.1    Skrobanski, P.2    Losy, J.3
  • 139
    • 79955757104 scopus 로고    scopus 로고
    • Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke
    • Rodriguez-Gonzalez R, Sobrino T, Rodriguez-Yanez M, et al. Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke. J Transl Med 2011; 9: 58.
    • (2011) J Transl Med , vol.9 , pp. 58
    • Rodriguez-Gonzalez, R.1    Sobrino, T.2    Rodriguez-Yanez, M.3
  • 141
    • 0029192212 scopus 로고
    • Tumor necrosis factor in sepsis: Mediator of multiple organ failure or essential part of host defense?
    • van der Poll T, Lowry SF. Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense? Shock 1995; 3: 1-12.
    • (1995) Shock , vol.3 , pp. 1-12
    • Van Der Poll, T.1    Lowry, S.F.2
  • 142
    • 13944274907 scopus 로고    scopus 로고
    • Cytokines and vascular reactivity in resistance arteries
    • Vila E, Salaices M. Cytokines and vascular reactivity in resistance arteries. Am J Physiol Heart Circ Physiol 2005; 288: H1016-21.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. H1016-H1421
    • Vila, E.1    Salaices, M.2
  • 143
    • 0028934328 scopus 로고
    • Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood flow in the rabbit: Role of nitric oxide
    • Tureen J. Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood flow in the rabbit: role of nitric oxide. J Clin Invest 1995; 95: 1086-91.
    • (1995) J Clin Invest , vol.95 , pp. 1086-1091
    • Tureen, J.1
  • 144
    • 0036908651 scopus 로고    scopus 로고
    • The many faces of tumor necrosis factor in stroke
    • Hallenbeck JM. The many faces of tumor necrosis factor in stroke. Nat Med 2002; 8: 1363-8.
    • (2002) Nat Med , vol.8 , pp. 1363-1368
    • Hallenbeck, J.M.1
  • 145
    • 84926299151 scopus 로고    scopus 로고
    • Effect of circulating factors on cerebral artery function during hyperglycemic stroke
    • Cipolla MJ, Sweet JG, Gardner-Morse I. Effect of circulating factors on cerebral artery function during hyperglycemic stroke. FASEB J 2011; 25:10246.
    • (2011) FASEB J , vol.25 , pp. 10246
    • Cipolla, M.J.1    Sweet, J.G.2    Gardner-Morse, I.3
  • 146
    • 33644927535 scopus 로고    scopus 로고
    • Flow-mediated dilatation and intima-media thickness in patients with lacunar infarctions
    • Pretnar-Oblak J, Sabovic M, Pogacnik T, Sebestjen M, Zaletel M. Flow-mediated dilatation and intima-media thickness in patients with lacunar infarctions. Acta Neurol Scand 2006; 113: 273-7.
    • (2006) Acta Neurol Scand , vol.113 , pp. 273-277
    • Pretnar-Oblak, J.1    Sabovic, M.2    Pogacnik, T.3    Sebestjen, M.4    Zaletel, M.5
  • 147
    • 33749028158 scopus 로고    scopus 로고
    • Influence of atorvastatin treatment on L-arginine cerebrovascular reactivity and flow-mediated dilatation in patients with lacunar infarctions
    • Pretnar-Oblak J, Sabovic M, Sebestjen M, Pogacnik T, Zaletel M. Influence of atorvastatin treatment on L-arginine cerebrovascular reactivity and flow-mediated dilatation in patients with lacunar infarctions. Stroke 2006; 37: 2540-5.
    • (2006) Stroke , vol.37 , pp. 2540-2545
    • Pretnar-Oblak, J.1    Sabovic, M.2    Sebestjen, M.3    Pogacnik, T.4    Zaletel, M.5
  • 148
  • 149
    • 0037046992 scopus 로고    scopus 로고
    • Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke
    • Williams LS, Rotich J, Qi R, et al. Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke. Neurology 2002; 59: 67-71.
    • (2002) Neurology , vol.59 , pp. 67-71
    • Williams, L.S.1    Rotich, J.2    Qi, R.3
  • 150
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001; 414: 813-20.
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 151
    • 0028271766 scopus 로고
    • High glucose downregulates glucose transport activity in retinal capillary pericytes but not endothelial cells
    • Mandarino LJ, Finlayson J, Hassell JR. High glucose downregulates glucose transport activity in retinal capillary pericytes but not endothelial cells. Invest Ophthalmol Vis Sci 1994; 35: 964-72.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 964-972
    • Mandarino, L.J.1    Finlayson, J.2    Hassell, J.R.3
  • 152
    • 33847215407 scopus 로고    scopus 로고
    • Hyperglycemia in acute ischemic stroke: A vascular perspective
    • Martini SR, Kent TA. Hyperglycemia in acute ischemic stroke: a vascular perspective. J Cereb Blood Flow Metab 2007; 27: 435-51.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 435-451
    • Martini, S.R.1    Kent, T.A.2
  • 153
    • 66049141178 scopus 로고    scopus 로고
    • Cerebral vascular dysregulation in the ischemic brain
    • Kunz A, Iadecola C. Cerebral vascular dysregulation in the ischemic brain. Handb Clin Neurol 2009; 92: 283-305.
    • (2009) Handb Clin Neurol , vol.92 , pp. 283-305
    • Kunz, A.1    Iadecola, C.2


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