Impaired endothelium-derived hyperpolarizing factor-mediated dilations and increased blood pressure in mice deficient of the intermediate-conductance Ca 2+-activated K + channel

Circulation Research

Volumn 99, Issue 5, 2006, Pages 537-544

  Si, Han ^a   Heyken, Willm Thomas ^a   Wölfle, Stephanie E ^b   Tysiac, Marcin ^a   Schubert, Rudolf ^c   Grgic, Ivica ^a   Vilianovich, Larisa ^d   Giebing, Günter ^a   Maier, Tanja ^a   Gross, Volkmar ^d   Bader, Michael ^d   De Wit, Cor ^b   Hoyer, Joachim ^a   Köhler, Ralf ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c UNIVERSITY OF ROSTOCK   (Germany)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

EDHF; Endothelium; Hypertension; Intermediate conductance Ca 2+ activated K + channel; K Ca3.1 mice

Indexed keywords

POTASSIUM CHANNEL; PROTEIN EDHF; PROTEIN INHIBITOR; TRAM 34; UCL 1684; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTERIAL PRESSURE; ARTICLE; CALCIUM CONDUCTANCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; GENE DELETION; GENE MUTATION; GENE TARGETING; HEART DILATATION; HYPERTENSION; MICROSCOPY; MYOGRAPHY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN FUNCTION; SMOOTH MUSCLE;

ACETYLCHOLINE; ANIMALS; AORTA; ARTERIOLES; BIOLOGICAL FACTORS; BLOOD PRESSURE; CAROTID ARTERIES; ELECTROPHYSIOLOGY; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HYPERTROPHY, LEFT VENTRICULAR; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCLE, SMOOTH, VASCULAR; PATCH-CLAMP TECHNIQUES; VASCULAR RESISTANCE; VASODILATION; VASODILATOR AGENTS;

EID: 33748345798     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000238377.08219.0c     Document Type: Article

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