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Volumn 55, Issue 3, 2008, Pages 281-288

Regulation of cerebral vasculature in normal and ischemic brain

Author keywords

Astrocytes; Cerebral arterial microcirculation; Cerebral blood flow regulation; Functional hyperemia; Hypotension; Ischemia

Indexed keywords

ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BLOOD VESSEL INNERVATION; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN MICROCIRCULATION; HUMAN; NEUROANATOMY; NONHUMAN; PATHOPHYSIOLOGY; PIA ARTERY; PRIORITY JOURNAL; STROKE;

EID: 48849095338     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2008.04.017     Document Type: Article
Times cited : (118)

References (125)
  • 1
    • 0036319335 scopus 로고    scopus 로고
    • Astrocyte-endothelial interactions and blood-brain barrier permeability
    • Abbott N.J. Astrocyte-endothelial interactions and blood-brain barrier permeability. J. Anat. 200 (2002) 629-638
    • (2002) J. Anat. , vol.200 , pp. 629-638
    • Abbott, N.J.1
  • 4
    • 2342471420 scopus 로고    scopus 로고
    • The blood-brain barrier: an overview: structure, regulation, and clinical implications
    • Ballabh P., Braun A., and Nedergaard M. The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol. Dis. 16 (2004) 1-13
    • (2004) Neurobiol. Dis. , vol.16 , pp. 1-13
    • Ballabh, P.1    Braun, A.2    Nedergaard, M.3
  • 5
    • 84944486665 scopus 로고
    • On the local reactions of the arterial wall to changes of internal pressure
    • Bayliss N. On the local reactions of the arterial wall to changes of internal pressure. J. Physiol. 28 (1902) 220-231
    • (1902) J. Physiol. , vol.28 , pp. 220-231
    • Bayliss, N.1
  • 6
    • 0036139877 scopus 로고    scopus 로고
    • Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains
    • Bushong E.A., Martone M.E., Jones Y.Z., and Ellisman M.H. Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J. Neurosci. 22 (2002) 183-192
    • (2002) J. Neurosci. , vol.22 , pp. 183-192
    • Bushong, E.A.1    Martone, M.E.2    Jones, Y.Z.3    Ellisman, M.H.4
  • 7
    • 0018830079 scopus 로고
    • Effects of sympathetic nerves on cerebral vessels during acute, moderate increases in arterial pressure in dogs and cats
    • Busija D.W., Heistad D.D., and Marcus M.L. Effects of sympathetic nerves on cerebral vessels during acute, moderate increases in arterial pressure in dogs and cats. Circ. Res. 46 (1980) 696-702
    • (1980) Circ. Res. , vol.46 , pp. 696-702
    • Busija, D.W.1    Heistad, D.D.2    Marcus, M.L.3
  • 8
  • 9
    • 33646470444 scopus 로고    scopus 로고
    • Evolving paradigms for neuroprotection: molecular identification of ischemic penumbra
    • Castellanos M., Sobrino T., and Castillo J. Evolving paradigms for neuroprotection: molecular identification of ischemic penumbra. Cerebrovasc. Dis. 21 Suppl. 2 (2006) 71-79
    • (2006) Cerebrovasc. Dis. , vol.21 , Issue.SUPPL. 2 , pp. 71-79
    • Castellanos, M.1    Sobrino, T.2    Castillo, J.3
  • 10
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • Chan P.H. Reactive oxygen radicals in signaling and damage in the ischemic brain. J. Cereb. Blood Flow Metab. 21 (2001) 2-14
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 2-14
    • Chan, P.H.1
  • 11
    • 0021879103 scopus 로고
    • An unanesthetized-gerbil model of cerebral ischemia-induced behavioral changes
    • Chandler M.J., et al. An unanesthetized-gerbil model of cerebral ischemia-induced behavioral changes. J. Pharmacol. Methods 14 (1985) 137-146
    • (1985) J. Pharmacol. Methods , vol.14 , pp. 137-146
    • Chandler, M.J.1
  • 12
    • 48849111709 scopus 로고    scopus 로고
    • Chien, S., Usami, S., Skalak, R., 1984. Blood flow in small tubes. In: Handbook of Physiology, pp. 217-250.
    • Chien, S., Usami, S., Skalak, R., 1984. Blood flow in small tubes. In: Handbook of Physiology, pp. 217-250.
  • 13
    • 0025265926 scopus 로고
    • The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
    • Choi D.W., and Rothman S.M. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 13 (1990) 171-182
    • (1990) Annu. Rev. Neurosci. , vol.13 , pp. 171-182
    • Choi, D.W.1    Rothman, S.M.2
  • 14
    • 0034934959 scopus 로고    scopus 로고
    • Threshold duration of ischemia for myogenic tone in middle cerebral arteries: effect on vascular smooth muscle actin
    • Cipolla M.J., Lessov N., Hammer E.S., and Curry A.B. Threshold duration of ischemia for myogenic tone in middle cerebral arteries: effect on vascular smooth muscle actin. Stroke 32 (2001) 1658-1664
    • (2001) Stroke , vol.32 , pp. 1658-1664
    • Cipolla, M.J.1    Lessov, N.2    Hammer, E.S.3    Curry, A.B.4
  • 15
    • 0031017446 scopus 로고    scopus 로고
    • High glucose concentrations dilate cerebral arteries and diminish myogenic tone through an endothelial mechanism
    • discussion, 410-411
    • Cipolla M.J., Porter J.M., and Osol G. High glucose concentrations dilate cerebral arteries and diminish myogenic tone through an endothelial mechanism. Stroke 28 (1997) 405-410 discussion, 410-411
    • (1997) Stroke , vol.28 , pp. 405-410
    • Cipolla, M.J.1    Porter, J.M.2    Osol, G.3
  • 16
    • 0030792733 scopus 로고    scopus 로고
    • Astroglial and vascular interactions of noradrenaline terminals in the rat cerebral cortex
    • Cohen Z., Molinatti G., and Hamel E. Astroglial and vascular interactions of noradrenaline terminals in the rat cerebral cortex. J. Cereb. Blood Flow Metab. 17 (1997) 894-904
    • (1997) J. Cereb. Blood Flow Metab. , vol.17 , pp. 894-904
    • Cohen, Z.1    Molinatti, G.2    Hamel, E.3
  • 17
    • 0028127716 scopus 로고
    • The human brain GLUT1 glucose transporter: an ultrastructural localization to the blood-brain barrier endothelia
    • Cornford E.M., Hymann S., and Swartz B.E. The human brain GLUT1 glucose transporter: an ultrastructural localization to the blood-brain barrier endothelia. J. Cereb. Blood Flow Metab. 14 (1994) 106-112
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 106-112
    • Cornford, E.M.1    Hymann, S.2    Swartz, B.E.3
  • 18
    • 0037201950 scopus 로고    scopus 로고
    • Methods for isolation and characterization of intracerebral arterioles in the C57/BL6 wild-type mouse
    • Coyne E.F., Ngai A.C., Meno J.R., and Winn H.R. Methods for isolation and characterization of intracerebral arterioles in the C57/BL6 wild-type mouse. J. Neurosci. Methods 120 (2002) 145-153
    • (2002) J. Neurosci. Methods , vol.120 , pp. 145-153
    • Coyne, E.F.1    Ngai, A.C.2    Meno, J.R.3    Winn, H.R.4
  • 19
    • 0015383306 scopus 로고
    • Sympathetic control of cerebral blood flow in dogs
    • D'Alecy L.G., and Feigl E.O. Sympathetic control of cerebral blood flow in dogs. Circ. Res. 31 (1972) 267-283
    • (1972) Circ. Res. , vol.31 , pp. 267-283
    • D'Alecy, L.G.1    Feigl, E.O.2
  • 20
    • 0029846131 scopus 로고    scopus 로고
    • Local and conducted vasomotor responses in isolated rat cerebral arterioles
    • Dietrich H.H., Kajita Y., and Dacey Jr. R.G. Local and conducted vasomotor responses in isolated rat cerebral arterioles. Am. J. Physiol. 271 (1996) H1109-H1116
    • (1996) Am. J. Physiol. , vol.271
    • Dietrich, H.H.1    Kajita, Y.2    Dacey Jr., R.G.3
  • 21
    • 0014190890 scopus 로고
    • Inversion of the Fahraeus-Lindqvist phenomenon in blood flow through capillaries of diminishing radius
    • Dintenfass L. Inversion of the Fahraeus-Lindqvist phenomenon in blood flow through capillaries of diminishing radius. Nature 215 (1967) 1099-1100
    • (1967) Nature , vol.215 , pp. 1099-1100
    • Dintenfass, L.1
  • 22
    • 0028292941 scopus 로고
    • Cortical hypoperfusion after global forebrain ischemia in rats is not caused by microvascular leukocyte plugging
    • Dirnagl U., Niwa K., Sixt G., and Villringer A. Cortical hypoperfusion after global forebrain ischemia in rats is not caused by microvascular leukocyte plugging. Stroke 25 (1994) 1028-1038
    • (1994) Stroke , vol.25 , pp. 1028-1038
    • Dirnagl, U.1    Niwa, K.2    Sixt, G.3    Villringer, A.4
  • 23
    • 0001331302 scopus 로고
    • The viscosity of blood in narrow capillary tubes
    • Fahraeus R., and Lindqvist T. The viscosity of blood in narrow capillary tubes. Am. J. Physiol. 96 (1931) 562-568
    • (1931) Am. J. Physiol. , vol.96 , pp. 562-568
    • Fahraeus, R.1    Lindqvist, T.2
  • 24
    • 0025097985 scopus 로고
    • Regulation of large cerebral arteries and cerebral microvascular pressure
    • Faraci F.M., and Heistad D.D. Regulation of large cerebral arteries and cerebral microvascular pressure. Circ. Res. 66 (1990) 8-17
    • (1990) Circ. Res. , vol.66 , pp. 8-17
    • Faraci, F.M.1    Heistad, D.D.2
  • 25
    • 0026063037 scopus 로고
    • Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary lumenal and ablumenal membranes: an electron microscopic immunogold study
    • Farrell C.L., and Pardridge W.M. Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary lumenal and ablumenal membranes: an electron microscopic immunogold study. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 5779-5783
    • (1991) Proc. Natl. Acad. Sci. U.S.A. , vol.88 , pp. 5779-5783
    • Farrell, C.L.1    Pardridge, W.M.2
  • 26
    • 0031953483 scopus 로고    scopus 로고
    • Neural control of coronary blood flow
    • Feigl E.O. Neural control of coronary blood flow. J. Vasc. Res. 35 (1998) 85-92
    • (1998) J. Vasc. Res. , vol.35 , pp. 85-92
    • Feigl, E.O.1
  • 27
    • 0030959940 scopus 로고    scopus 로고
    • Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects
    • Folbergrova J., Li P.A., Uchino H., Smith M.L., and Siesjo B.K. Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects. Exp. Brain. Res. 114 (1997) 44-50
    • (1997) Exp. Brain. Res. , vol.114 , pp. 44-50
    • Folbergrova, J.1    Li, P.A.2    Uchino, H.3    Smith, M.L.4    Siesjo, B.K.5
  • 28
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott R.F., and Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288 (1980) 373-376
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 29
    • 0344430068 scopus 로고    scopus 로고
    • Electrical stimulation of the dorsal periaqueductal gray decreases volume of the brain infarction independently of accompanying hypertension and cerebrovasodilation
    • Glickstein S.B., Ilch C.P., and Golanov E.V. Electrical stimulation of the dorsal periaqueductal gray decreases volume of the brain infarction independently of accompanying hypertension and cerebrovasodilation. Brain Res. 994 (2003) 135-145
    • (2003) Brain Res. , vol.994 , pp. 135-145
    • Glickstein, S.B.1    Ilch, C.P.2    Golanov, E.V.3
  • 30
    • 0035979859 scopus 로고    scopus 로고
    • Stimulation of the subthalamic vasodilator area and fastigial nucleus independently protects the brain against focal ischemia
    • Glickstein S.B., Ilch C.P., Reis D.J., and Golanov E.V. Stimulation of the subthalamic vasodilator area and fastigial nucleus independently protects the brain against focal ischemia. Brain Res. 912 (2001) 47-59
    • (2001) Brain Res. , vol.912 , pp. 47-59
    • Glickstein, S.B.1    Ilch, C.P.2    Reis, D.J.3    Golanov, E.V.4
  • 31
    • 0025191257 scopus 로고
    • Congruence of total and perfused capillary network in rat brains
    • Gobel U., Theilen H., and Kuschinsky W. Congruence of total and perfused capillary network in rat brains. Circ. Res. 66 (1990) 271-281
    • (1990) Circ. Res. , vol.66 , pp. 271-281
    • Gobel, U.1    Theilen, H.2    Kuschinsky, W.3
  • 32
    • 34547797327 scopus 로고    scopus 로고
    • Astrocyte control of the cerebrovasculature
    • Gordon G.R., Mulligan S.J., and MacVicar B.A. Astrocyte control of the cerebrovasculature. Glia 55 (2007) 1214-1221
    • (2007) Glia , vol.55 , pp. 1214-1221
    • Gordon, G.R.1    Mulligan, S.J.2    MacVicar, B.A.3
  • 33
    • 34250317399 scopus 로고    scopus 로고
    • Synaptic islands defined by the territory of a single astrocyte
    • Halassa M.M., Fellin T., Takano H., Dong J.H., and Haydon P.G. Synaptic islands defined by the territory of a single astrocyte. J. Neurosci. 27 (2007) 6473-6477
    • (2007) J. Neurosci. , vol.27 , pp. 6473-6477
    • Halassa, M.M.1    Fellin, T.2    Takano, H.3    Dong, J.H.4    Haydon, P.G.5
  • 34
    • 33645809129 scopus 로고    scopus 로고
    • Perivascular nerves and the regulation of cerebrovascular tone
    • Hamel E. Perivascular nerves and the regulation of cerebrovascular tone. J. Appl. Physiol. 100 (2006) 1059-1064
    • (2006) J. Appl. Physiol. , vol.100 , pp. 1059-1064
    • Hamel, E.1
  • 35
    • 0016792225 scopus 로고
    • Ultrastructural studies on cerebrovascular permeability in acute hypertension
    • Hansson H.A., Johansson B., and Blomstrand C. Ultrastructural studies on cerebrovascular permeability in acute hypertension. Acta Neuropathol. 32 (1975) 187-198
    • (1975) Acta Neuropathol. , vol.32 , pp. 187-198
    • Hansson, H.A.1    Johansson, B.2    Blomstrand, C.3
  • 36
    • 0031002404 scopus 로고    scopus 로고
    • Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue
    • Harder D.R., Lange A.R., Gebremedhin D., Birks E.K., and Roman R.J. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J. Vasc. Res. 34 (1997) 237-243
    • (1997) J. Vasc. Res. , vol.34 , pp. 237-243
    • Harder, D.R.1    Lange, A.R.2    Gebremedhin, D.3    Birks, E.K.4    Roman, R.J.5
  • 37
    • 22944483792 scopus 로고    scopus 로고
    • The blood-brain barrier/neurovascular unit in health and disease
    • Hawkins B.T., and Davis T.P. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 57 (2005) 173-185
    • (2005) Pharmacol. Rev. , vol.57 , pp. 173-185
    • Hawkins, B.T.1    Davis, T.P.2
  • 38
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovascular coupling
    • Haydon P.G., and Carmignoto G. Astrocyte control of synaptic transmission and neurovascular coupling. Physiol. Rev. 86 (2006) 1009-1031
    • (2006) Physiol. Rev. , vol.86 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 40
    • 0018060213 scopus 로고
    • Effects of sympathetic nerves on cerebral vessels in dog, cat, and monkey
    • Heistad D.D., Marcus M.L., and Gross P.M. Effects of sympathetic nerves on cerebral vessels in dog, cat, and monkey. Am. J. Physiol. 235 (1978) H544-H552
    • (1978) Am. J. Physiol. , vol.235
    • Heistad, D.D.1    Marcus, M.L.2    Gross, P.M.3
  • 41
    • 0001890760 scopus 로고
    • Effect of acetylcholine and vasoactive intestinal peptide on cerebral blood flow
    • Heistad D.D., Marcus M.L., Said S.I., and Gross P.M. Effect of acetylcholine and vasoactive intestinal peptide on cerebral blood flow. Am. J. Physiol. 239 (1980) H73-H80
    • (1980) Am. J. Physiol. , vol.239
    • Heistad, D.D.1    Marcus, M.L.2    Said, S.I.3    Gross, P.M.4
  • 42
    • 34848873498 scopus 로고    scopus 로고
    • Stimulating circle of Willis nerve fibers preserves the diffusion-perfusion mismatch in experimental stroke
    • Henninger N., and Fisher M. Stimulating circle of Willis nerve fibers preserves the diffusion-perfusion mismatch in experimental stroke. Stroke 38 (2007) 2779-2786
    • (2007) Stroke , vol.38 , pp. 2779-2786
    • Henninger, N.1    Fisher, M.2
  • 43
    • 48849088677 scopus 로고    scopus 로고
    • Bioenergetics of cerebral ischemia: a cellular perspective
    • Hertz L. Bioenergetics of cerebral ischemia: a cellular perspective. Neuropharmacology 55 3 (2008) 289-309
    • (2008) Neuropharmacology , vol.55 , Issue.3 , pp. 289-309
    • Hertz, L.1
  • 44
    • 0036124663 scopus 로고    scopus 로고
    • Hippocampal injury and neurobehavioral deficits following hyperglycemic cerebral ischemia: effect of theophylline and ZM 241385
    • Higashi H., Meno J.R., Marwaha A.S., and Winn H.R. Hippocampal injury and neurobehavioral deficits following hyperglycemic cerebral ischemia: effect of theophylline and ZM 241385. J. Neurosurg. 96 (2002) 117-126
    • (2002) J. Neurosurg. , vol.96 , pp. 117-126
    • Higashi, H.1    Meno, J.R.2    Marwaha, A.S.3    Winn, H.R.4
  • 45
    • 0025272491 scopus 로고
    • Pressure-flow relations in coronary circulation
    • Hoffman J.I., and Spaan J.A. Pressure-flow relations in coronary circulation. Physiol. Rev. 70 (1990) 331-390
    • (1990) Physiol. Rev. , vol.70 , pp. 331-390
    • Hoffman, J.I.1    Spaan, J.A.2
  • 46
  • 47
    • 33845547792 scopus 로고    scopus 로고
    • Pathophysiology and therapy of experimental stroke
    • Hossmann K.A. Pathophysiology and therapy of experimental stroke. Cell. Mol. Neurobiol. 26 (2006) 1057-1083
    • (2006) Cell. Mol. Neurobiol. , vol.26 , pp. 1057-1083
    • Hossmann, K.A.1
  • 48
    • 0028008143 scopus 로고
    • Moderate hyperglycemia affects ischemic brain ATP levels but not intracellular pH
    • Hsu S.S., Meno J.R., Gronka R., Kushmerick M., and Winn H.R. Moderate hyperglycemia affects ischemic brain ATP levels but not intracellular pH. Am. J. Physiol. 266 (1994) H258-H262
    • (1994) Am. J. Physiol. , vol.266
    • Hsu, S.S.1    Meno, J.R.2    Gronka, R.3    Kushmerick, M.4    Winn, H.R.5
  • 49
    • 0025993167 scopus 로고
    • Influence of hyperglycemia on cerebral adenosine production during ischemia and reperfusion
    • Hsu S.S., Meno J.R., Zhou J.G., Gordon E.L., and Winn H.R. Influence of hyperglycemia on cerebral adenosine production during ischemia and reperfusion. Am. J. Physiol. 261 (1991) H398-H403
    • (1991) Am. J. Physiol. , vol.261
    • Hsu, S.S.1    Meno, J.R.2    Zhou, J.G.3    Gordon, E.L.4    Winn, H.R.5
  • 50
    • 35548969443 scopus 로고    scopus 로고
    • Glial regulation of the cerebral microvasculature
    • Iadecola C., and Nedergaard M. Glial regulation of the cerebral microvasculature. Nat. Neurosci. 10 (2007) 1369-1376
    • (2007) Nat. Neurosci. , vol.10 , pp. 1369-1376
    • Iadecola, C.1    Nedergaard, M.2
  • 51
    • 0025900396 scopus 로고
    • Lack of sympathetic and cholinergic influences on cerebral vasodilation caused by sciatic nerve stimulation in the rat
    • Ibayashi S., Ngai A.C., Howard III M.A., Meno J.R., Mayberg M.R., and Winn H.R. Lack of sympathetic and cholinergic influences on cerebral vasodilation caused by sciatic nerve stimulation in the rat. J. Cereb. Blood Flow Metab. 11 (1991) 678-683
    • (1991) J. Cereb. Blood Flow Metab. , vol.11 , pp. 678-683
    • Ibayashi, S.1    Ngai, A.C.2    Howard III, M.A.3    Meno, J.R.4    Mayberg, M.R.5    Winn, H.R.6
  • 52
    • 33751261138 scopus 로고    scopus 로고
    • Endothelium-dependent regulation of cerebrovascular tone by extracellular and intracellular ATP
    • Janigro D., Nguyen T.S., Meno J., West G.A., and Winn H.R. Endothelium-dependent regulation of cerebrovascular tone by extracellular and intracellular ATP. Am. J. Physiol. 273 (1997) H878-H885
    • (1997) Am. J. Physiol. , vol.273
    • Janigro, D.1    Nguyen, T.S.2    Meno, J.3    West, G.A.4    Winn, H.R.5
  • 54
    • 0024988426 scopus 로고
    • The physiology of the blood-brain barrier
    • Johansson B.B. The physiology of the blood-brain barrier. Adv. Exp. Med. Biol. 274 (1990) 25-39
    • (1990) Adv. Exp. Med. Biol. , vol.274 , pp. 25-39
    • Johansson, B.B.1
  • 55
    • 0014792772 scopus 로고
    • On the mode of entry of blood vessels into the cerebral cortex
    • Jones E.G. On the mode of entry of blood vessels into the cerebral cortex. J. Anat. 106 (1970) 507-520
    • (1970) J. Anat. , vol.106 , pp. 507-520
    • Jones, E.G.1
  • 56
    • 50849084813 scopus 로고    scopus 로고
    • Kawasaki, T., Ago, Y., Kitao, T., Nashida, T., Takagi, A., Takuma, K., Matsuda, T. A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. Neuropharmacology, in press. doi:10.1016/j.neuropharm.2008.05.032.
    • Kawasaki, T., Ago, Y., Kitao, T., Nashida, T., Takagi, A., Takuma, K., Matsuda, T. A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl}azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. Neuropharmacology, in press. doi:10.1016/j.neuropharm.2008.05.032.
  • 57
    • 0021125297 scopus 로고
    • Rheology of the cerebral circulation
    • Kee Jr. D.B., and Wood J.H. Rheology of the cerebral circulation. Neurosurgery 15 (1984) 125-131
    • (1984) Neurosurgery , vol.15 , pp. 125-131
    • Kee Jr., D.B.1    Wood, J.H.2
  • 58
    • 0023005833 scopus 로고
    • Interdependency of local capillary density, blood flow, and metabolism in rat brains
    • Klein B., Kuschinsky W., Schrock H., and Vetterlein F. Interdependency of local capillary density, blood flow, and metabolism in rat brains. Am. J. Physiol. 251 (1986) H1333-H1340
    • (1986) Am. J. Physiol. , vol.251
    • Klein, B.1    Kuschinsky, W.2    Schrock, H.3    Vetterlein, F.4
  • 59
    • 0021356707 scopus 로고
    • Blood flow velocity in the pial arteries of cats, with particular reference to the vessel diameter
    • Kobari M., Gotoh F., Fukuuchi Y., Tanaka K., Suzuki N., and Uematsu D. Blood flow velocity in the pial arteries of cats, with particular reference to the vessel diameter. J. Cereb. Blood Flow Metab. 4 (1984) 110-114
    • (1984) J. Cereb. Blood Flow Metab. , vol.4 , pp. 110-114
    • Kobari, M.1    Gotoh, F.2    Fukuuchi, Y.3    Tanaka, K.4    Suzuki, N.5    Uematsu, D.6
  • 63
    • 78651147122 scopus 로고
    • Glia in the leech central nervous system: physiological properties and neuron-glia relationship
    • Kuffler S.W., and Potter D.D. Glia in the leech central nervous system: physiological properties and neuron-glia relationship. J. Neurophysiol. 27 (1964) 290-320
    • (1964) J. Neurophysiol. , vol.27 , pp. 290-320
    • Kuffler, S.W.1    Potter, D.D.2
  • 64
    • 0030976784 scopus 로고    scopus 로고
    • Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows
    • Kuroda S., and Siesjo B.K. Reperfusion damage following focal ischemia: pathophysiology and therapeutic windows. Clin. Neurosci. 4 (1997) 199-212
    • (1997) Clin. Neurosci. , vol.4 , pp. 199-212
    • Kuroda, S.1    Siesjo, B.K.2
  • 66
    • 27844518332 scopus 로고    scopus 로고
    • The critical component to establish in vitro BBB model: pericyte. Brain Res. Brain Res
    • Lai C.H., and Kuo K.H. The critical component to establish in vitro BBB model: pericyte. Brain Res. Brain Res. Rev. 50 (2005) 258-265
    • (2005) Rev. , vol.50 , pp. 258-265
    • Lai, C.H.1    Kuo, K.H.2
  • 67
    • 0025953731 scopus 로고
    • Hyperglycemia and neurological outcome in patients with head injury
    • Lam A.M., Winn H.R., Cullen B.F., and Sundling N. Hyperglycemia and neurological outcome in patients with head injury. J. Neurosurg. 75 (1991) 545-551
    • (1991) J. Neurosurg. , vol.75 , pp. 545-551
    • Lam, A.M.1    Winn, H.R.2    Cullen, B.F.3    Sundling, N.4
  • 68
    • 33745988312 scopus 로고    scopus 로고
    • Neuron-glia metabolic coupling and plasticity
    • Magistretti P.J. Neuron-glia metabolic coupling and plasticity. J. Exp. Biol. 209 (2006) 2304-2311
    • (2006) J. Exp. Biol. , vol.209 , pp. 2304-2311
    • Magistretti, P.J.1
  • 69
    • 0022067278 scopus 로고
    • Permeability of blood-brain barrier to various sized molecules
    • Mayhan W.G., and Heistad D.D. Permeability of blood-brain barrier to various sized molecules. Am. J. Physiol. 248 (1985) H712-H718
    • (1985) Am. J. Physiol. , vol.248
    • Mayhan, W.G.1    Heistad, D.D.2
  • 70
    • 0022550654 scopus 로고
    • Role of veins and cerebral venous pressure in disruption of the blood-brain barrier
    • Mayhan W.G., and Heistad D.D. Role of veins and cerebral venous pressure in disruption of the blood-brain barrier. Circ. Res. 59 (1986) 216-220
    • (1986) Circ. Res. , vol.59 , pp. 216-220
    • Mayhan, W.G.1    Heistad, D.D.2
  • 71
    • 0021160759 scopus 로고
    • The modular organization of the pial arterial system in phylogeny
    • McHedlishvili G., and Kuridze N. The modular organization of the pial arterial system in phylogeny. J. Cereb. Blood Flow Metab. 4 (1984) 391-396
    • (1984) J. Cereb. Blood Flow Metab. , vol.4 , pp. 391-396
    • McHedlishvili, G.1    Kuridze, N.2
  • 72
    • 0042738121 scopus 로고    scopus 로고
    • Hippocampal injury and neurobehavioral deficits are improved by PD 81,723 following hyperglycemic cerebral ischemia
    • Meno J.R., Higashi H., Cambray A.J., Zhou J., D'Ambrosio R., and Winn H.R. Hippocampal injury and neurobehavioral deficits are improved by PD 81,723 following hyperglycemic cerebral ischemia. Exp. Neurol. 183 (2003) 188-196
    • (2003) Exp. Neurol. , vol.183 , pp. 188-196
    • Meno, J.R.1    Higashi, H.2    Cambray, A.J.3    Zhou, J.4    D'Ambrosio, R.5    Winn, H.R.6
  • 73
    • 0027405912 scopus 로고
    • Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia
    • Meno J.R., Ngai A.C., and Winn H.R. Changes in pial arteriolar diameter and CSF adenosine concentrations during hypoxia. J. Cereb. Blood Flow Metab. 13 (1993) 214-220
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 214-220
    • Meno, J.R.1    Ngai, A.C.2    Winn, H.R.3
  • 74
    • 0022607349 scopus 로고
    • Reactivity of rat pial arterioles and venules to adenosine and carbon dioxide: with detailed description of the closed cranial window technique in rats
    • Morii S., Ngai A.C., and Winn H.R. Reactivity of rat pial arterioles and venules to adenosine and carbon dioxide: with detailed description of the closed cranial window technique in rats. J. Cereb. Blood Flow Metab. 6 (1986) 34-41
    • (1986) J. Cereb. Blood Flow Metab. , vol.6 , pp. 34-41
    • Morii, S.1    Ngai, A.C.2    Winn, H.R.3
  • 75
    • 0038180539 scopus 로고    scopus 로고
    • Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response
    • Muller W.A. Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response. Trends Immunol. 24 (2003) 327-334
    • (2003) Trends Immunol. , vol.24 , pp. 327-334
    • Muller, W.A.1
  • 76
    • 0027158001 scopus 로고
    • Characterization of cortical depolarizations evoked in focal cerebral ischemia
    • Nedergaard M., and Hansen A.J. Characterization of cortical depolarizations evoked in focal cerebral ischemia. J. Cereb. Blood Flow Metab. 13 (1993) 568-574
    • (1993) J. Cereb. Blood Flow Metab. , vol.13 , pp. 568-574
    • Nedergaard, M.1    Hansen, A.J.2
  • 77
    • 0141533205 scopus 로고    scopus 로고
    • New roles for astrocytes: redefining the functional architecture of the brain
    • Nedergaard M., Ransom B., and Goldman S.A. New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci. 26 (2003) 523-530
    • (2003) Trends Neurosci. , vol.26 , pp. 523-530
    • Nedergaard, M.1    Ransom, B.2    Goldman, S.A.3
  • 78
    • 0036718797 scopus 로고    scopus 로고
    • Beyond the role of glutamate as a neurotransmitter
    • Nedergaard M., Takano T., and Hansen A.J. Beyond the role of glutamate as a neurotransmitter. Nat. Rev. Neurosci. 3 (2002) 748-755
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 748-755
    • Nedergaard, M.1    Takano, T.2    Hansen, A.J.3
  • 79
    • 0141867841 scopus 로고    scopus 로고
    • New roles for astrocytes: regulation of synaptic transmission
    • Newman E.A. New roles for astrocytes: regulation of synaptic transmission. Trends Neurosci. 26 (2003) 536-542
    • (2003) Trends Neurosci. , vol.26 , pp. 536-542
    • Newman, E.A.1
  • 80
    • 0023840436 scopus 로고
    • Effect of sciatic nerve stimulation on pial arterioles in rats
    • Ngai A.C., Ko K.R., Morii S., and Winn H.R. Effect of sciatic nerve stimulation on pial arterioles in rats. Am. J. Physiol. 254 (1988) H133-H139
    • (1988) Am. J. Physiol. , vol.254
    • Ngai, A.C.1    Ko, K.R.2    Morii, S.3    Winn, H.R.4
  • 81
    • 33845935173 scopus 로고    scopus 로고
    • Postischemic augmentation of conducted dilation in cerebral arterioles
    • Ngai A.C., Nguyen T.S., Meno J.R., and Britz G.W. Postischemic augmentation of conducted dilation in cerebral arterioles. Stroke 38 (2007) 124-130
    • (2007) Stroke , vol.38 , pp. 124-130
    • Ngai, A.C.1    Nguyen, T.S.2    Meno, J.R.3    Britz, G.W.4
  • 82
    • 0027237192 scopus 로고
    • Effects of adenosine and its analogues on isolated intracerebral arterioles. Extraluminal and intraluminal application
    • Ngai A.C., and Winn H.R. Effects of adenosine and its analogues on isolated intracerebral arterioles. Extraluminal and intraluminal application. Circ. Res. 73 (1993) 448-457
    • (1993) Circ. Res. , vol.73 , pp. 448-457
    • Ngai, A.C.1    Winn, H.R.2
  • 83
    • 0029128412 scopus 로고
    • Modulation of cerebral arteriolar diameter by intraluminal flow and pressure
    • Ngai A.C., and Winn H.R. Modulation of cerebral arteriolar diameter by intraluminal flow and pressure. Circ. Res. 77 (1995) 832-840
    • (1995) Circ. Res. , vol.77 , pp. 832-840
    • Ngai, A.C.1    Winn, H.R.2
  • 84
    • 0017819634 scopus 로고
    • Effects of phenobarbital in cerebral ischemia. Part I: cerebral energy metabolism during pronounced incomplete ischemia
    • Nordstrom C.H., and Siesjo B.K. Effects of phenobarbital in cerebral ischemia. Part I: cerebral energy metabolism during pronounced incomplete ischemia. Stroke 9 (1978) 327-335
    • (1978) Stroke , vol.9 , pp. 327-335
    • Nordstrom, C.H.1    Siesjo, B.K.2
  • 86
    • 0031049236 scopus 로고    scopus 로고
    • Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy
    • Obrenovitch T.P., and Urenjak J. Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy. Prog. Neurobiol. 51 (1997) 39-87
    • (1997) Prog. Neurobiol. , vol.51 , pp. 39-87
    • Obrenovitch, T.P.1    Urenjak, J.2
  • 87
    • 0017487289 scopus 로고
    • The large apparent work capability of the blood-brain barrier: a study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat
    • Oldendorf W.H., Cornford M.E., and Brown W.J. The large apparent work capability of the blood-brain barrier: a study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat. Ann. Neurol. 1 (1977) 409-417
    • (1977) Ann. Neurol. , vol.1 , pp. 409-417
    • Oldendorf, W.H.1    Cornford, M.E.2    Brown, W.J.3
  • 88
    • 33749860102 scopus 로고    scopus 로고
    • Bidirectional control of CNS capillary diameter by pericytes
    • Peppiatt C.M., Howarth C., Mobbs P., and Attwell D. Bidirectional control of CNS capillary diameter by pericytes. Nature 443 7112 (2006) 700-704
    • (2006) Nature , vol.443 , Issue.7112 , pp. 700-704
    • Peppiatt, C.M.1    Howarth, C.2    Mobbs, P.3    Attwell, D.4
  • 89
    • 0037727888 scopus 로고    scopus 로고
    • Lactate as a pivotal element in neuron-glia metabolic cooperation
    • Pellerin L. Lactate as a pivotal element in neuron-glia metabolic cooperation. Neurochem. Int. 43 (2003) 331-338
    • (2003) Neurochem. Int. , vol.43 , pp. 331-338
    • Pellerin, L.1
  • 90
    • 33747368249 scopus 로고    scopus 로고
    • Blood-brain barrier: structural components and function under physiologic and pathologic conditions
    • Persidsky Y., Ramirez S.H., Haorah J., and Kanmogne G.D. Blood-brain barrier: structural components and function under physiologic and pathologic conditions. J. Neuroimmune. Pharmacol. 1 (2006) 223-236
    • (2006) J. Neuroimmune. Pharmacol. , vol.1 , pp. 223-236
    • Persidsky, Y.1    Ramirez, S.H.2    Haorah, J.3    Kanmogne, G.D.4
  • 91
    • 0018347695 scopus 로고
    • A new model of bilateral hemispheric ischemia in the unanesthetized rat
    • Pulsinelli W.A., and Brierley J.B. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10 (1979) 267-272
    • (1979) Stroke , vol.10 , pp. 267-272
    • Pulsinelli, W.A.1    Brierley, J.B.2
  • 92
    • 0020211722 scopus 로고
    • Moderate hyperglycemia augments ischemic brain damage: a neuropathologic study in the rat
    • Pulsinelli W.A., Waldman S., Rawlinson D., and Plum F. Moderate hyperglycemia augments ischemic brain damage: a neuropathologic study in the rat. Neurology 32 (1982) 1239-1246
    • (1982) Neurology , vol.32 , pp. 1239-1246
    • Pulsinelli, W.A.1    Waldman, S.2    Rawlinson, D.3    Plum, F.4
  • 93
    • 0004280434 scopus 로고
    • Anatomy of cerebral blood vessels
    • Cambridge University Press, Cambridge
    • Purves M. Anatomy of cerebral blood vessels. The Physiology of the Cerebral Circulation (1972), Cambridge University Press, Cambridge
    • (1972) The Physiology of the Cerebral Circulation
    • Purves, M.1
  • 95
    • 0141533210 scopus 로고    scopus 로고
    • New roles for astrocytes (stars at last)
    • Ransom B., Behar T., and Nedergaard M. New roles for astrocytes (stars at last). Trends Neurosci. 26 (2003) 520-522
    • (2003) Trends Neurosci. , vol.26 , pp. 520-522
    • Ransom, B.1    Behar, T.2    Nedergaard, M.3
  • 96
    • 0015386057 scopus 로고
    • Unresponsiveness of pial precapillary vessels to catecholamines and sympathetic nerve stimulation
    • Raper A.J., Kontos H.A., Wei E.P., and Patterson Jr. J.L. Unresponsiveness of pial precapillary vessels to catecholamines and sympathetic nerve stimulation. Circ. Res. 31 (1972) 257-266
    • (1972) Circ. Res. , vol.31 , pp. 257-266
    • Raper, A.J.1    Kontos, H.A.2    Wei, E.P.3    Patterson Jr., J.L.4
  • 97
    • 16244403317 scopus 로고    scopus 로고
    • In situ immunoradiographic method for quantification of specific proteins in normal and ischemic brain regions
    • Rebel A., Koehler R.C., and Martin L.J. In situ immunoradiographic method for quantification of specific proteins in normal and ischemic brain regions. J. Neurosci. Methods 143 (2005) 227-235
    • (2005) J. Neurosci. Methods , vol.143 , pp. 227-235
    • Rebel, A.1    Koehler, R.C.2    Martin, L.J.3
  • 98
    • 0031946956 scopus 로고    scopus 로고
    • Morphological characteristics and distribution pattern of the arterial vessels in human cerebral cortex: a scanning electron microscope study
    • Reina-De La Torre F., Rodriguez-Baeza A., and Sahuquillo-Barris J. Morphological characteristics and distribution pattern of the arterial vessels in human cerebral cortex: a scanning electron microscope study. Anat. Rec. 251 (1998) 87-96
    • (1998) Anat. Rec. , vol.251 , pp. 87-96
    • Reina-De La Torre, F.1    Rodriguez-Baeza, A.2    Sahuquillo-Barris, J.3
  • 99
    • 0031578856 scopus 로고    scopus 로고
    • Central neurogenic neuroprotection: central neural systems that protect the brain from hypoxia and ischemia
    • Reis D.J., Golanov E.V., Galea E., and Feinstein D.L. Central neurogenic neuroprotection: central neural systems that protect the brain from hypoxia and ischemia. Ann. N.Y. Acad. Sci. 835 (1997) 168-186
    • (1997) Ann. N.Y. Acad. Sci. , vol.835 , pp. 168-186
    • Reis, D.J.1    Golanov, E.V.2    Galea, E.3    Feinstein, D.L.4
  • 100
    • 0017351723 scopus 로고
    • Ultrastructure of arterioles in the cat brain
    • Roggendorf W., and Cervos-Navarro J. Ultrastructure of arterioles in the cat brain. Cell Tissue Res. 178 (1977) 495-515
    • (1977) Cell Tissue Res. , vol.178 , pp. 495-515
    • Roggendorf, W.1    Cervos-Navarro, J.2
  • 102
    • 35548957889 scopus 로고    scopus 로고
    • Astrocyte metabolism and signaling during brain ischemia
    • Rossi D.J., Brady J.D., and Mohr C. Astrocyte metabolism and signaling during brain ischemia. Nat. Neurosci. 10 (2007) 1377-1386
    • (2007) Nat. Neurosci. , vol.10 , pp. 1377-1386
    • Rossi, D.J.1    Brady, J.D.2    Mohr, C.3
  • 103
    • 0025049276 scopus 로고
    • Mechanoreception by the endothelium: mediators and mechanisms of pressure- and flow-induced vascular responses
    • Rubanyi G.M., Freay A.D., Kauser K., Johns A., and Harder D.R. Mechanoreception by the endothelium: mediators and mechanisms of pressure- and flow-induced vascular responses. Blood Vessels 27 (1990) 246-257
    • (1990) Blood Vessels , vol.27 , pp. 246-257
    • Rubanyi, G.M.1    Freay, A.D.2    Kauser, K.3    Johns, A.4    Harder, D.R.5
  • 104
    • 0032936851 scopus 로고    scopus 로고
    • The cell biology of the blood-brain barrier
    • Rubin L.L., and Staddon J.M. The cell biology of the blood-brain barrier. Annu. Rev. Neurosci. 22 (1999) 11-28
    • (1999) Annu. Rev. Neurosci. , vol.22 , pp. 11-28
    • Rubin, L.L.1    Staddon, J.M.2
  • 105
    • 0344654742 scopus 로고    scopus 로고
    • Nervous control of the cerebrovascular system: doubts and facts
    • Sandor P. Nervous control of the cerebrovascular system: doubts and facts. Neurochem. Int. 35 (1999) 237-259
    • (1999) Neurochem. Int. , vol.35 , pp. 237-259
    • Sandor, P.1
  • 106
    • 0036336618 scopus 로고    scopus 로고
    • Bench-to-bedside review: a possible resolution of the glucose paradox of cerebral ischemia
    • Schurr A. Bench-to-bedside review: a possible resolution of the glucose paradox of cerebral ischemia. Crit. Care. 6 (2002) 330-334
    • (2002) Crit. Care. , vol.6 , pp. 330-334
    • Schurr, A.1
  • 107
    • 0024508833 scopus 로고
    • Propagation of vasomotor responses coordinates arteriolar resistances
    • Segal S.S., Damon D.N., and Duling B.R. Propagation of vasomotor responses coordinates arteriolar resistances. Am. J. Physiol. 256 (1989) H832-H837
    • (1989) Am. J. Physiol. , vol.256
    • Segal, S.S.1    Damon, D.N.2    Duling, B.R.3
  • 109
    • 0001173865 scopus 로고
    • Focal intimal proliferation in the cerebral arteries
    • Stehbens W.E. Focal intimal proliferation in the cerebral arteries. Am. J. Pathol. 36 (1960) 289-301
    • (1960) Am. J. Pathol. , vol.36 , pp. 289-301
    • Stehbens, W.E.1
  • 114
    • 0023948101 scopus 로고
    • Development of membrane interactions between brain endothelial cells and astrocytes in vitro
    • Tao-Cheng J.H., and Brightman M.W. Development of membrane interactions between brain endothelial cells and astrocytes in vitro. Int. J. Dev. Neurosci. 6 (1988) 25-37
    • (1988) Int. J. Dev. Neurosci. , vol.6 , pp. 25-37
    • Tao-Cheng, J.H.1    Brightman, M.W.2
  • 115
    • 0033964124 scopus 로고    scopus 로고
    • Cerebral vasodilatation induced by stimulation of the pterygopalatine ganglion and greater petrosal nerve in anesthetized monkeys
    • Toda N., Tanaka T., Ayajiki K., and Okamura T. Cerebral vasodilatation induced by stimulation of the pterygopalatine ganglion and greater petrosal nerve in anesthetized monkeys. Neuroscience 96 (2000) 393-398
    • (2000) Neuroscience , vol.96 , pp. 393-398
    • Toda, N.1    Tanaka, T.2    Ayajiki, K.3    Okamura, T.4
  • 116
    • 33847425398 scopus 로고
    • Ultrastructure of capillary reaction to brain tumors
    • Torack R.M. Ultrastructure of capillary reaction to brain tumors. Arch. Neurol. 5 (1961) 416-428
    • (1961) Arch. Neurol. , vol.5 , pp. 416-428
    • Torack, R.M.1
  • 117
    • 23044435896 scopus 로고    scopus 로고
    • Astrocytes, from brain glue to communication elements: the revolution continues
    • Volterra A., and Meldolesi J. Astrocytes, from brain glue to communication elements: the revolution continues. Nat. Rev. Neurosci. 6 (2005) 626-640
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 626-640
    • Volterra, A.1    Meldolesi, J.2
  • 118
    • 0030934096 scopus 로고    scopus 로고
    • Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin alpha 6 beta 4 during focal cerebral ischemia/reperfusion
    • Wagner S., Tagaya M., Koziol J.A., Quaranta V., and del Zoppo G.J. Rapid disruption of an astrocyte interaction with the extracellular matrix mediated by integrin alpha 6 beta 4 during focal cerebral ischemia/reperfusion. Stroke 28 (1997) 858-865
    • (1997) Stroke , vol.28 , pp. 858-865
    • Wagner, S.1    Tagaya, M.2    Koziol, J.A.3    Quaranta, V.4    del Zoppo, G.J.5
  • 119
    • 0018729531 scopus 로고
    • Brain adenosine production in the rat during 60 seconds of ischemia
    • Winn H.R., Rubio R., and Berne R.M. Brain adenosine production in the rat during 60 seconds of ischemia. Circ. Res. 45 (1979) 486-492
    • (1979) Circ. Res. , vol.45 , pp. 486-492
    • Winn, H.R.1    Rubio, R.2    Berne, R.M.3
  • 121
    • 39149123170 scopus 로고    scopus 로고
    • Astrocytes are a key conduit for upstream signaling of vasodilation during cerebral cortical neuronal activation in vivo
    • Xu H.L., Mao L., Ye S., Paisansathan C., Vetri F., and Pelligrino D.A. Astrocytes are a key conduit for upstream signaling of vasodilation during cerebral cortical neuronal activation in vivo. Am. J. Physiol. Heart Circ. Physiol. 294 (2008) H622-H632
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294
    • Xu, H.L.1    Mao, L.2    Ye, S.3    Paisansathan, C.4    Vetri, F.5    Pelligrino, D.A.6
  • 122
    • 0034192486 scopus 로고    scopus 로고
    • Advances in the vascular pathophysiology of ischemic stroke
    • del Zoppo G.J., and Hallenbeck J.M. Advances in the vascular pathophysiology of ischemic stroke. Thromb. Res. 98 (2000) 73-81
    • (2000) Thromb. Res. , vol.98 , pp. 73-81
    • del Zoppo, G.J.1    Hallenbeck, J.M.2
  • 123
    • 36249003722 scopus 로고    scopus 로고
    • General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage
    • Zhao H., Steinberg G.K., and Sapolsky R.M. General versus specific actions of mild-moderate hypothermia in attenuating cerebral ischemic damage. J. Cereb. Blood Flow Metab. 27 (2007) 1879-1894
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 1879-1894
    • Zhao, H.1    Steinberg, G.K.2    Sapolsky, R.M.3
  • 124
    • 0028047656 scopus 로고
    • Effects of theophylline and cyclohexyladenosine on brain injury following normo- and hyperglycemic ischemia: a histopathologic study in the rat
    • Zhou J.G., Meno J.R., Hsu S.S., and Winn H.R. Effects of theophylline and cyclohexyladenosine on brain injury following normo- and hyperglycemic ischemia: a histopathologic study in the rat. J. Cereb. Blood Flow Metab. 14 (1994) 166-173
    • (1994) J. Cereb. Blood Flow Metab. , vol.14 , pp. 166-173
    • Zhou, J.G.1    Meno, J.R.2    Hsu, S.S.3    Winn, H.R.4


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