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Volumn 16, Issue 2, 2015, Pages 110-123

Mechanisms of retinoic acid signalling and its roles in organ and limb development

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; RETINOIC ACID; RETINOIC ACID RECEPTOR;

EID: 84923199000     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm3932     Document Type: Review
Times cited : (441)

References (159)
  • 1
    • 84989611379 scopus 로고
    • Tissue changes following deprivation of fat-soluble a vitamin
    • Wolbach, S. B. & Howe, P. R. Tissue changes following deprivation of fat-soluble A vitamin. J. Exp. Med. 42, 753-777 (1925).
    • (1925) J. Exp. Med. , vol.42 , pp. 753-777
    • Wolbach, S.B.1    Howe, P.R.2
  • 2
    • 0000411901 scopus 로고
    • Cutaneous lesions associated with a deficiency in vitamin a in man
    • Frazier, C. N. & Hu, C. K. Cutaneous lesions associated with a deficiency in vitamin A in man. Arch. Intern. Med. 48, 507-514 (1931).
    • (1931) Arch. Intern. Med. , vol.48 , pp. 507-514
    • Frazier, C.N.1    Hu, C.K.2
  • 3
    • 84958699162 scopus 로고
    • An analysis of the syndrome of malformations induced by maternal vitamin a deficiency. Effects of restoration of vitamin a at various times during gestation
    • Wilson, J. G., Roth, C. B. & Warkany, J. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Amer. J. Anat. 92, 189-217 (1953).
    • (1953) Amer. J. Anat. , vol.92 , pp. 189-217
    • Wilson, J.G.1    Roth, C.B.2    Warkany, J.3
  • 4
    • 0036029643 scopus 로고    scopus 로고
    • The role of vitamin a in mammalian reproduction and embryonic development
    • Clagett-Dame, M. & DeLuca, H. F. The role of vitamin A in mammalian reproduction and embryonic development. Annu. Rev. Nutr. 22, 347-381 (2002).
    • (2002) Annu. Rev. Nutr. , vol.22 , pp. 347-381
    • Clagett-Dame, M.1    Deluca, H.F.2
  • 5
    • 0001571206 scopus 로고
    • Vitamin a deficiency and night blindness
    • Dowling, J. E. & Wald, G. Vitamin A deficiency and night blindness. Proc. Natl Acad. Sci. USA 44, 648-661 (1958).
    • (1958) Proc. Natl Acad. Sci. USA , vol.44 , pp. 648-661
    • Dowling, J.E.1    Wald, G.2
  • 6
    • 0014983786 scopus 로고
    • Formation of retinoic acid from retinol in the kidney
    • Kleiner-Bossaler, A. & DeLuca, H. F. Formation of retinoic acid from retinol in the kidney. Arch. Biochem. Biophys. 142, 371-377 (1971).
    • (1971) Arch. Biochem. Biophys. , vol.142 , pp. 371-377
    • Kleiner-Bossaler, A.1    Deluca, H.F.2
  • 7
    • 0015785215 scopus 로고
    • Limb development in mouse embryos i. Analysis of teratogenic effects of retinoic acid
    • Kochhar, D. M. Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid. Teratology 7, 289-298 (1973).
    • (1973) Teratology , vol.7 , pp. 289-298
    • Kochhar, D.M.1
  • 8
    • 0020316590 scopus 로고
    • Local application of retinoic acid to the limb bud mimics the action of the polarizing region
    • Tickle, C., Alberts, B. M., Wolpert, L. & Lee, J. Local application of retinoic acid to the limb bud mimics the action of the polarizing region. Nature 296, 564-565 (1982).
    • (1982) Nature , vol.296 , pp. 564-565
    • Tickle, C.1    Alberts, B.M.2    Wolpert, L.3    Lee, J.4
  • 9
    • 0020057749 scopus 로고
    • Vitamin a and pattern formation in the regenerating limb
    • Maden, M. Vitamin A and pattern formation in the regenerating limb. Nature 295, 672-675 (1982).
    • (1982) Nature , vol.295 , pp. 672-675
    • Maden, M.1
  • 10
    • 0023483399 scopus 로고
    • A human retinoic acid receptor which belongs to the family of nuclear receptors
    • Petkovich, M., Brand, N. J., Krust, A. & Chambon, P. A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature 330, 444-450 (1987).
    • (1987) Nature , vol.330 , pp. 444-450
    • Petkovich, M.1    Brand, N.J.2    Krust, A.3    Chambon, P.4
  • 11
    • 0023520940 scopus 로고
    • Identification of a receptor for the morphogen retinoic acid
    • Giguére, V., Ong, E. S., Segui, P. & Evans, R. M. Identification of a receptor for the morphogen retinoic acid. Nature 330, 624-629 (1987).
    • (1987) Nature , vol.330 , pp. 624-629
    • Giguére, V.1    Ong, E.S.2    Segui, P.3    Evans, R.M.4
  • 12
    • 0032958632 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
    • Niederreither, K., Subbarayan, V., Dollé, P. & Chambon, P. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nature Genet. 21, 444-448 (1999).
    • (1999) Nature Genet. , vol.21 , pp. 444-448
    • Niederreither, K.1    Subbarayan, V.2    Dollé, P.3    Chambon, P.4
  • 13
    • 45549091674 scopus 로고    scopus 로고
    • Retinoic acid in development: Towards an integrated view
    • Niederreither, K. & Dolle, P. Retinoic acid in development: towards an integrated view. Nature Rev. Genet. 9, 541-553 (2008).
    • (2008) Nature Rev. Genet. , vol.9 , pp. 541-553
    • Niederreither, K.1    Dolle, P.2
  • 14
    • 51549116267 scopus 로고    scopus 로고
    • Retinoic acid synthesis and signaling during early organogenesis
    • Duester, G. Retinoic acid synthesis and signaling during early organogenesis. Cell 134, 921-931 (2008).
    • (2008) Cell , vol.134 , pp. 921-931
    • Duester, G.1
  • 15
    • 0000561938 scopus 로고
    • Retinoic acid in skin and epithelia
    • Darmon, M. Retinoic acid in skin and epithelia. Sem. Dev. Biol. 2, 219-228 (1991).
    • (1991) Sem Dev. Biol. , vol.2 , pp. 219-228
    • Darmon, M.1
  • 16
    • 84867367107 scopus 로고    scopus 로고
    • Retinoic acid induces sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis
    • Raverdeau, M. et al. Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis. Proc. Natl Acad. Sci. USA 109, 16582-16587 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 16582-16587
    • Raverdeau, M.1
  • 17
    • 84897553364 scopus 로고    scopus 로고
    • Modulation of t cell and innate immune responses by retinoic acid
    • Raverdeau, M. & Mills, K. H. Modulation of T cell and innate immune responses by retinoic acid. J. Immunol. 192, 2953-2958 (2014).
    • (2014) J. Immunol. , vol.192 , pp. 2953-2958
    • Raverdeau, M.1    Mills, K.H.2
  • 19
    • 78649646015 scopus 로고    scopus 로고
    • Retinoids regulate stem cell differentiation
    • Gudas, L. J. & Wagner, J. A. Retinoids regulate stem cell differentiation. J. Cell. Physiol. 226, 322-330 (2011).
    • (2011) J. Cell. Physiol. , vol.226 , pp. 322-330
    • Gudas, L.J.1    Wagner, J.A.2
  • 20
    • 0029154931 scopus 로고
    • Polarity-specific activities of retinoic acid receptors determined by a co-repressor
    • Kurokawa, R. et al. Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 377, 451-454 (1995).
    • (1995) Nature , vol.377 , pp. 451-454
    • Kurokawa, R.1
  • 21
    • 0029097233 scopus 로고
    • A transcriptional co-repressor that interacts with nuclear hormone receptors
    • Chen, J. D. & Evans, R. M. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377, 454-457 (1995).
    • (1995) Nature , vol.377 , pp. 454-457
    • Chen, J.D.1    Evans, R.M.2
  • 22
    • 0037732643 scopus 로고    scopus 로고
    • Active repression by unliganded retinoid receptors in development: Less is sometimes more
    • Weston, A. D., Blumberg, B. & Underhill, T. M. Active repression by unliganded retinoid receptors in development: less is sometimes more. J. Cell Biol. 161, 223-228 (2003).
    • (2003) J. Cell Biol. , vol.161 , pp. 223-228
    • Weston, A.D.1    Blumberg, B.2    Underhill, T.M.3
  • 23
    • 84901430985 scopus 로고    scopus 로고
    • Active repression by rar signaling is required for vertebrate axial elongation
    • Janesick, A. et al. Active repression by RAR signaling is required for vertebrate axial elongation. Development 141, 2260-2270 (2014).
    • (2014) Development , vol.141 , pp. 2260-2270
    • Janesick, A.1
  • 24
    • 0030953186 scopus 로고    scopus 로고
    • Nuclear receptor repression mediated by a complex containing smrt, msin3a, and histone deacetylase
    • Nagy, L. et al. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89, 373-380 (1997).
    • (1997) Cell , vol.89 , pp. 373-380
    • Nagy, L.1
  • 25
    • 0034664769 scopus 로고    scopus 로고
    • Combinatorial roles of the nuclear receptor corepressor in transcription and development
    • Jepsen, K. et al. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102, 753-763 (2000).
    • (2000) Cell , vol.102 , pp. 753-763
    • Jepsen, K.1
  • 26
    • 34547941825 scopus 로고    scopus 로고
    • Retinoid regulated association of transcriptional co-regulators and the polycomb group protein suz12 with the retinoic acid response elements of hoxa1 rar2, and cyp26a1 in f9 embryonal carcinoma cells
    • Gillespie, R. F. & Gudas, L. J. Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RAR2, and Cyp26A1 in F9 embryonal carcinoma cells. J. Mol. Biol. 372, 298-316 (2007).
    • (2007) J. Mol. Biol. , vol.372 , pp. 298-316
    • Gillespie, R.F.1    Gudas, L.J.2
  • 27
    • 0032213938 scopus 로고    scopus 로고
    • Determinants of coactivator lxxll motif specificity in nuclear receptor transcriptional activation
    • McInerney, E. M. et al. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 12, 3357-3368 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 3357-3368
    • McInerney, E.M.1
  • 28
    • 77951992661 scopus 로고    scopus 로고
    • Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts
    • Kashyap, V. & Gudas, L. J. Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts. J. Biol. Chem. 285, 14534-14548 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 14534-14548
    • Kashyap, V.1    Gudas, L.J.2
  • 29
    • 79955581636 scopus 로고    scopus 로고
    • Common architecture of nuclear receptor heterodimers on dna direct repeat elements with different spacings
    • Rochel, N. et al. Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings. Nature Struct. Mol. Biol. 18, 564-570 (2011).
    • (2011) Nature Struct. Mol. Biol. , vol.18 , pp. 564-570
    • Rochel, N.1
  • 30
    • 84904607589 scopus 로고    scopus 로고
    • Retinoic acid controls body axis extension by directly repressing fgf8 transcription
    • Kumar, S. & Duester, G. Retinoic acid controls body axis extension by directly repressing Fgf8 transcription. Development 141, 2972-2977 (2014).
    • (2014) Development , vol.141 , pp. 2972-2977
    • Kumar, S.1    Duester, G.2
  • 31
    • 0028150628 scopus 로고
    • Role of a conserved retinoic acid response element in rhombomere restriction of hoxb-1
    • Studer, M., Pöpperl, H., Marshall, H., Kuroiwa, A. & Krumlauf, R. Role of a conserved retinoic acid response element in rhombomere restriction of Hoxb-1. Science 265, 1728-1732 (1994).
    • (1994) Science , vol.265 , pp. 1728-1732
    • Studer, M.1    Pöpperl, H.2    Marshall, H.3    Kuroiwa, A.4    Krumlauf, R.5
  • 32
    • 0025812291 scopus 로고
    • Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin d3 receptors
    • Umesono, K., Murakami, K. K., Thompson, C. C. & Evans, R. M. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell 65, 1255-1266 (1991).
    • (1991) Cell , vol.65 , pp. 1255-1266
    • Umesono, K.1    Murakami, K.K.2    Thompson, C.C.3    Evans, R.M.4
  • 33
    • 84995867020 scopus 로고
    • Ordered binding of retinoic acid and retinoid-x receptors to asymmetric response elements involves determinants adjacent to the dna-binding domain
    • Predki, P. F., Zamble, D., Sarkar, B. & Giguére, V. Ordered binding of retinoic acid and retinoid-x receptors to asymmetric response elements involves determinants adjacent to the DNA-binding domain. Mol. Endocrinol. 8, 31-39 (1994).
    • (1994) Mol. Endocrinol. , vol.8 , pp. 31-39
    • Predki, P.F.1    Zamble, D.2    Sarkar, B.3    Giguére, V.4
  • 34
    • 84864383302 scopus 로고    scopus 로고
    • Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology
    • Moutier, E. et al. Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology. J. Biol. Chem. 287, 26328-26341 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 26328-26341
    • Moutier, E.1
  • 35
    • 25644452125 scopus 로고    scopus 로고
    • A robust characterization of retinoic acid response elements based on a comparison of sites in three species
    • Balmer, J. E. & Blomhoff, R. A robust characterization of retinoic acid response elements based on a comparison of sites in three species. J. Steroid Biochem. Mol. Biol. 96, 347-354 (2005).
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.96 , pp. 347-354
    • Balmer, J.E.1    Blomhoff, R.2
  • 36
    • 0029562554 scopus 로고
    • The rxr heterodimers and orphan receptors
    • Mangelsdorf, D. J. & Evans, R. M. The RXR heterodimers and orphan receptors. Cell 83, 841-850 (1995).
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 37
    • 77249173175 scopus 로고    scopus 로고
    • Dna recognition by thyroid hormone and retinoic acid receptors 3,4,5 rule modified
    • Phan, T. Q., Jow, M. M. & Privalsky, M. L. DNA recognition by thyroid hormone and retinoic acid receptors: 3,4,5 rule modified. Mol. Cell. Endocrinol. 319, 88-98 (2010).
    • (2010) Mol. Cell. Endocrinol. , vol.319 , pp. 88-98
    • Phan, T.Q.1    Jow, M.M.2    Privalsky, M.L.3
  • 38
    • 0025685315 scopus 로고
    • Retinoic acid receptors and cellular retinoid binding proteins i. A systematic study of their differential pattern of transcription during mouse organogenesis
    • Dollé, P., Ruberte, E., Leroy, P., Morriss-Kay, G. & Chambon, P. Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development 110, 1133-1151 (1990).
    • (1990) Development , vol.110 , pp. 1133-1151
    • Dollé, P.1    Ruberte, E.2    Leroy, P.3    Morriss-Kay, G.4    Chambon, P.5
  • 39
    • 0028009121 scopus 로고
    • Developmental expression of murine retinoid x receptor (rxr) genes
    • Dollé, P., Fraulob, V., Kastner, P. & Chambon, P. Developmental expression of murine retinoid X receptor (RXR) genes. Mech. Dev. 45, 91-104 (1994).
    • (1994) Mech. Dev. , vol.45 , pp. 91-104
    • Dollé, P.1    Fraulob, V.2    Kastner, P.3    Chambon, P.4
  • 40
    • 0026055409 scopus 로고
    • Expression of a retinoic acid response element-hsplacz transgene defines specific domains of transcriptional activity during mouse embryogenesis
    • Rossant, J., Zirngibl, R., Cado, D., Shago, M. & Giguére, V. Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev. 5, 1333-1344 (1991).
    • (1991) Genes Dev. , vol.5 , pp. 1333-1344
    • Rossant, J.1    Zirngibl, R.2    Cado, D.3    Shago, M.4    Giguére, V.5
  • 41
    • 0035162208 scopus 로고    scopus 로고
    • Retinoic acid-mediated gene expression in transgenic reporter zebrafish
    • Perz-Edwards, A., Hardison, N. L. & Linney, E. Retinoic acid-mediated gene expression in transgenic reporter zebrafish. Dev. Biol. 229, 89-101 (2001).
    • (2001) Dev. Biol. , vol.229 , pp. 89-101
    • Perz-Edwards, A.1    Hardison, N.L.2    Linney, E.3
  • 42
    • 84876294515 scopus 로고    scopus 로고
    • Visualization of an endogenous retinoic acid gradient across embryonic development
    • Shimozono, S., Iimura, T., Kitaguchi, T., Higashijima, S. & Miyawaki, A. Visualization of an endogenous retinoic acid gradient across embryonic development. Nature 496, 363-366 (2013).
    • (2013) Nature , vol.496 , pp. 363-366
    • Shimozono, S.1    Iimura, T.2    Kitaguchi, T.3    Higashijima, S.4    Miyawaki, A.5
  • 43
    • 44949239539 scopus 로고    scopus 로고
    • Retinoic acid controls heart anteroposterior patterning by down-regulating isl1 through the fgf8 pathway
    • Sirbu, I. O., Zhao, X. & Duester, G. Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway. Dev. Dyn. 237, 1627-1635 (2008).
    • (2008) Dev. Dyn. , vol.237 , pp. 1627-1635
    • Sirbu, I.O.1    Zhao, X.2    Duester, G.3
  • 44
    • 0141862018 scopus 로고    scopus 로고
    • Opposing fgf and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension
    • Diez del Corral, R. et al. Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron 40, 65-79 (2003).
    • (2003) Neuron , vol.40 , pp. 65-79
    • Diez Del Corral, R.1
  • 45
    • 0033786946 scopus 로고    scopus 로고
    • Opposing ra and fgf signals control proximodistal vertebrate limb development through regulation of meis genes
    • Mercader, N. et al. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development 127, 3961-3970 (2000).
    • (2000) Development , vol.127 , pp. 3961-3970
    • Mercader, N.1
  • 46
    • 79957626589 scopus 로고    scopus 로고
    • Diffusible signals, not autonomous mechanisms, determine the main proximodistal limb subdivision
    • Rosello-Diez, A., Ros, M. A. & Torres, M. Diffusible signals, not autonomous mechanisms, determine the main proximodistal limb subdivision. Science 332, 1086-1088 (2011).
    • (2011) Science , vol.332 , pp. 1086-1088
    • Rosello-Diez, A.1    Ros, M.A.2    Torres, M.3
  • 47
    • 84989611379 scopus 로고
    • Tissue changes following deprivation of fat-soluble a vitamin
    • Wolbach, S. B. & Howe, P. R. Tissue changes following deprivation of fat-soluble A vitamin. J. Exp. Med. 42, 753-777 (1925).
    • (1925) J. Exp. Med. , vol.42 , pp. 753-777
    • Wolbach, S.B.1    Howe, P.R.2
  • 48
    • 0000411901 scopus 로고
    • Cutaneous lesions associated with a deficiency in vitamin a in man
    • Frazier, C. N. & Hu, C. K. Cutaneous lesions associated with a deficiency in vitamin A in man. Arch. Intern. Med. 48, 507-514 (1931).
    • (1931) Arch. Intern. Med. , vol.48 , pp. 507-514
    • Frazier, C.N.1    Hu, C.K.2
  • 49
    • 84958699162 scopus 로고
    • An analysis of the syndrome of malformations induced by maternal vitamin a deficiency. Effects of restoration of vitamin a at various times during gestation
    • Wilson, J. G., Roth, C. B. & Warkany, J. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Amer. J. Anat. 92, 189-217 (1953).
    • (1953) Amer. J. Anat. , vol.92 , pp. 189-217
    • Wilson, J.G.1    Roth, C.B.2    Warkany, J.3
  • 50
    • 0036029643 scopus 로고    scopus 로고
    • The role of vitamin a in mammalian reproduction and embryonic development
    • Clagett-Dame, M. & DeLuca, H. F. The role of vitamin A in mammalian reproduction and embryonic development. Annu. Rev. Nutr. 22, 347-381 (2002).
    • (2002) Annu. Rev. Nutr. , vol.22 , pp. 347-381
    • Clagett-Dame, M.1    Deluca, H.F.2
  • 51
    • 0001571206 scopus 로고
    • Vitamin a deficiency and night blindness
    • Dowling, J. E. & Wald, G. Vitamin A deficiency and night blindness. Proc. Natl Acad. Sci. USA 44, 648-661 (1958).
    • (1958) Proc. Natl Acad. Sci. USA , vol.44 , pp. 648-661
    • Dowling, J.E.1    Wald, G.2
  • 52
    • 0014983786 scopus 로고
    • Formation of retinoic acid from retinol in the kidney
    • Kleiner-Bossaler, A. & DeLuca, H. F. Formation of retinoic acid from retinol in the kidney. Arch. Biochem. Biophys. 142, 371-377 (1971).
    • (1971) Arch. Biochem. Biophys. , vol.142 , pp. 371-377
    • Kleiner-Bossaler, A.1    Deluca, H.F.2
  • 53
    • 0015785215 scopus 로고
    • Limb development in mouse embryos i. Analysis of teratogenic effects of retinoic acid
    • Kochhar, D. M. Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid. Teratology 7, 289-298 (1973).
    • (1973) Teratology , vol.7 , pp. 289-298
    • Kochhar, D.M.1
  • 54
    • 0020316590 scopus 로고
    • Local application of retinoic acid to the limb bud mimics the action of the polarizing region
    • Tickle, C., Alberts, B. M., Wolpert, L. & Lee, J. Local application of retinoic acid to the limb bud mimics the action of the polarizing region. Nature 296, 564-565 (1982).
    • (1982) Nature , vol.296 , pp. 564-565
    • Tickle, C.1    Alberts, B.M.2    Wolpert, L.3    Lee, J.4
  • 55
    • 0020057749 scopus 로고
    • Vitamin a and pattern formation in the regenerating limb
    • Maden, M. Vitamin A and pattern formation in the regenerating limb. Nature 295, 672-675 (1982).
    • (1982) Nature , vol.295 , pp. 672-675
    • Maden, M.1
  • 56
    • 0023483399 scopus 로고
    • A human retinoic acid receptor which belongs to the family of nuclear receptors
    • Petkovich, M., Brand, N. J., Krust, A. & Chambon, P. A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature 330, 444-450 (1987).
    • (1987) Nature , vol.330 , pp. 444-450
    • Petkovich, M.1    Brand, N.J.2    Krust, A.3    Chambon, P.4
  • 57
    • 0023520940 scopus 로고
    • Identification of a receptor for the morphogen retinoic acid
    • Giguére, V., Ong, E. S., Segui, P. & Evans, R. M. Identification of a receptor for the morphogen retinoic acid. Nature 330, 624-629 (1987).
    • (1987) Nature , vol.330 , pp. 624-629
    • Giguére, V.1    Ong, E.S.2    Segui, P.3    Evans, R.M.4
  • 58
    • 0032958632 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
    • Niederreither, K., Subbarayan, V., Dollé, P. & Chambon, P. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nature Genet. 21, 444-448 (1999).
    • (1999) Nature Genet. , vol.21 , pp. 444-448
    • Niederreither, K.1    Subbarayan, V.2    Dollé, P.3    Chambon, P.4
  • 59
    • 45549091674 scopus 로고    scopus 로고
    • Retinoic acid in development: Towards an integrated view
    • Niederreither, K. & Dolle, P. Retinoic acid in development: towards an integrated view. Nature Rev. Genet. 9, 541-553 (2008).
    • (2008) Nature Rev. Genet. , vol.9 , pp. 541-553
    • Niederreither, K.1    Dolle, P.2
  • 60
    • 51549116267 scopus 로고    scopus 로고
    • Retinoic acid synthesis and signaling during early organogenesis
    • Duester, G. Retinoic acid synthesis and signaling during early organogenesis. Cell 134, 921-931 (2008).
    • (2008) Cell , vol.134 , pp. 921-931
    • Duester, G.1
  • 61
    • 0000561938 scopus 로고
    • Retinoic acid in skin and epithelia
    • Darmon, M. Retinoic acid in skin and epithelia. Sem. Dev. Biol. 2, 219-228 (1991).
    • (1991) Sem Dev. Biol. , vol.2 , pp. 219-228
    • Darmon, M.1
  • 62
    • 84867367107 scopus 로고    scopus 로고
    • Retinoic acid induces sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis
    • Raverdeau, M. et al. Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis. Proc. Natl Acad. Sci. USA 109, 16582-16587 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 16582-16587
    • Raverdeau, M.1
  • 63
    • 84897553364 scopus 로고    scopus 로고
    • Modulation of t cell and innate immune responses by retinoic acid
    • Raverdeau, M. & Mills, K. H. Modulation of T cell and innate immune responses by retinoic acid. J. Immunol. 192, 2953-2958 (2014).
    • (2014) J. Immunol. , vol.192 , pp. 2953-2958
    • Raverdeau, M.1    Mills, K.H.2
  • 65
    • 78649646015 scopus 로고    scopus 로고
    • Retinoids regulate stem cell differentiation
    • Gudas, L. J. & Wagner, J. A. Retinoids regulate stem cell differentiation. J. Cell. Physiol. 226, 322-330 (2011).
    • (2011) J. Cell. Physiol. , vol.226 , pp. 322-330
    • Gudas, L.J.1    Wagner, J.A.2
  • 66
    • 0029154931 scopus 로고
    • Polarity-specific activities of retinoic acid receptors determined by a co-repressor
    • Kurokawa, R. et al. Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 377, 451-454 (1995).
    • (1995) Nature , vol.377 , pp. 451-454
    • Kurokawa, R.1
  • 67
    • 0029097233 scopus 로고
    • A transcriptional co-repressor that interacts with nuclear hormone receptors
    • Chen, J. D. & Evans, R. M. A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature 377, 454-457 (1995).
    • (1995) Nature , vol.377 , pp. 454-457
    • Chen, J.D.1    Evans, R.M.2
  • 68
    • 0037732643 scopus 로고    scopus 로고
    • Active repression by unliganded retinoid receptors in development: Less is sometimes more
    • Weston, A. D., Blumberg, B. & Underhill, T. M. Active repression by unliganded retinoid receptors in development: less is sometimes more. J. Cell Biol. 161, 223-228 (2003).
    • (2003) J. Cell Biol. , vol.161 , pp. 223-228
    • Weston, A.D.1    Blumberg, B.2    Underhill, T.M.3
  • 69
    • 84901430985 scopus 로고    scopus 로고
    • Active repression by rar signaling is required for vertebrate axial elongation
    • Janesick, A. et al. Active repression by RAR signaling is required for vertebrate axial elongation. Development 141, 2260-2270 (2014).
    • (2014) Development , vol.141 , pp. 2260-2270
    • Janesick, A.1
  • 70
    • 0030953186 scopus 로고    scopus 로고
    • Nuclear receptor repression mediated by a complex containing smrt, msin3a, and histone deacetylase
    • Nagy, L. et al. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89, 373-380 (1997).
    • (1997) Cell , vol.89 , pp. 373-380
    • Nagy, L.1
  • 71
    • 0034664769 scopus 로고    scopus 로고
    • Combinatorial roles of the nuclear receptor corepressor in transcription and development
    • Jepsen, K. et al. Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102, 753-763 (2000).
    • (2000) Cell , vol.102 , pp. 753-763
    • Jepsen, K.1
  • 72
    • 34547941825 scopus 로고    scopus 로고
    • Retinoid regulated association of transcriptional co-regulators and the polycomb group protein suz12 with the retinoic acid response elements of hoxa1 rar2, and cyp26a1 in f9 embryonal carcinoma cells
    • Gillespie, R. F. & Gudas, L. J. Retinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RAR2, and Cyp26A1 in F9 embryonal carcinoma cells. J. Mol. Biol. 372, 298-316 (2007).
    • (2007) J. Mol. Biol. , vol.372 , pp. 298-316
    • Gillespie, R.F.1    Gudas, L.J.2
  • 73
    • 0032213938 scopus 로고    scopus 로고
    • Determinants of coactivator lxxll motif specificity in nuclear receptor transcriptional activation
    • McInerney, E. M. et al. Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation. Genes Dev. 12, 3357-3368 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 3357-3368
    • McInerney, E.M.1
  • 74
    • 77951992661 scopus 로고    scopus 로고
    • Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts
    • Kashyap, V. & Gudas, L. J. Epigenetic regulatory mechanisms distinguish retinoic acid-mediated transcriptional responses in stem cells and fibroblasts. J. Biol. Chem. 285, 14534-14548 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 14534-14548
    • Kashyap, V.1    Gudas, L.J.2
  • 75
    • 79955581636 scopus 로고    scopus 로고
    • Common architecture of nuclear receptor heterodimers on dna direct repeat elements with different spacings
    • Rochel, N. et al. Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings. Nature Struct. Mol. Biol. 18, 564-570 (2011).
    • (2011) Nature Struct. Mol. Biol. , vol.18 , pp. 564-570
    • Rochel, N.1
  • 76
    • 84904607589 scopus 로고    scopus 로고
    • Retinoic acid controls body axis extension by directly repressing fgf8 transcription
    • Kumar, S. & Duester, G. Retinoic acid controls body axis extension by directly repressing Fgf8 transcription. Development 141, 2972-2977 (2014).
    • (2014) Development , vol.141 , pp. 2972-2977
    • Kumar, S.1    Duester, G.2
  • 77
    • 0028150628 scopus 로고
    • Role of a conserved retinoic acid response element in rhombomere restriction of hoxb-1
    • Studer, M., Pöpperl, H., Marshall, H., Kuroiwa, A. & Krumlauf, R. Role of a conserved retinoic acid response element in rhombomere restriction of Hoxb-1. Science 265, 1728-1732 (1994).
    • (1994) Science , vol.265 , pp. 1728-1732
    • Studer, M.1    Pöpperl, H.2    Marshall, H.3    Kuroiwa, A.4    Krumlauf, R.5
  • 78
    • 0025812291 scopus 로고
    • Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin d3 receptors
    • Umesono, K., Murakami, K. K., Thompson, C. C. & Evans, R. M. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell 65, 1255-1266 (1991).
    • (1991) Cell , vol.65 , pp. 1255-1266
    • Umesono, K.1    Murakami, K.K.2    Thompson, C.C.3    Evans, R.M.4
  • 79
    • 84995867020 scopus 로고
    • Ordered binding of retinoic acid and retinoid-x receptors to asymmetric response elements involves determinants adjacent to the dna-binding domain
    • Predki, P. F., Zamble, D., Sarkar, B. & Giguére, V. Ordered binding of retinoic acid and retinoid-x receptors to asymmetric response elements involves determinants adjacent to the DNA-binding domain. Mol. Endocrinol. 8, 31-39 (1994).
    • (1994) Mol. Endocrinol. , vol.8 , pp. 31-39
    • Predki, P.F.1    Zamble, D.2    Sarkar, B.3    Giguére, V.4
  • 80
    • 84864383302 scopus 로고    scopus 로고
    • Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology
    • Moutier, E. et al. Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology. J. Biol. Chem. 287, 26328-26341 (2012).
    • (2012) J. Biol. Chem. , vol.287 , pp. 26328-26341
    • Moutier, E.1
  • 81
    • 25644452125 scopus 로고    scopus 로고
    • A robust characterization of retinoic acid response elements based on a comparison of sites in three species
    • Balmer, J. E. & Blomhoff, R. A robust characterization of retinoic acid response elements based on a comparison of sites in three species. J. Steroid Biochem. Mol. Biol. 96, 347-354 (2005).
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.96 , pp. 347-354
    • Balmer, J.E.1    Blomhoff, R.2
  • 82
    • 0029562554 scopus 로고
    • The rxr heterodimers and orphan receptors
    • Mangelsdorf, D. J. & Evans, R. M. The RXR heterodimers and orphan receptors. Cell 83, 841-850 (1995).
    • (1995) Cell , vol.83 , pp. 841-850
    • Mangelsdorf, D.J.1    Evans, R.M.2
  • 83
    • 77249173175 scopus 로고    scopus 로고
    • Dna recognition by thyroid hormone and retinoic acid receptors 3,4,5 rule modified
    • Phan, T. Q., Jow, M. M. & Privalsky, M. L. DNA recognition by thyroid hormone and retinoic acid receptors: 3,4,5 rule modified. Mol. Cell. Endocrinol. 319, 88-98 (2010).
    • (2010) Mol. Cell. Endocrinol. , vol.319 , pp. 88-98
    • Phan, T.Q.1    Jow, M.M.2    Privalsky, M.L.3
  • 84
    • 0025685315 scopus 로고
    • Retinoic acid receptors and cellular retinoid binding proteins i. A systematic study of their differential pattern of transcription during mouse organogenesis
    • Dollé, P., Ruberte, E., Leroy, P., Morriss-Kay, G. & Chambon, P. Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development 110, 1133-1151 (1990).
    • (1990) Development , vol.110 , pp. 1133-1151
    • Dollé, P.1    Ruberte, E.2    Leroy, P.3    Morriss-Kay, G.4    Chambon, P.5
  • 85
    • 0028009121 scopus 로고
    • Developmental expression of murine retinoid x receptor (rxr) genes
    • Dollé, P., Fraulob, V., Kastner, P. & Chambon, P. Developmental expression of murine retinoid X receptor (RXR) genes. Mech. Dev. 45, 91-104 (1994).
    • (1994) Mech. Dev. , vol.45 , pp. 91-104
    • Dollé, P.1    Fraulob, V.2    Kastner, P.3    Chambon, P.4
  • 86
    • 0026055409 scopus 로고
    • Expression of a retinoic acid response element-hsplacz transgene defines specific domains of transcriptional activity during mouse embryogenesis
    • Rossant, J., Zirngibl, R., Cado, D., Shago, M. & Giguére, V. Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev. 5, 1333-1344 (1991).
    • (1991) Genes Dev. , vol.5 , pp. 1333-1344
    • Rossant, J.1    Zirngibl, R.2    Cado, D.3    Shago, M.4    Giguére, V.5
  • 87
    • 0035162208 scopus 로고    scopus 로고
    • Retinoic acid-mediated gene expression in transgenic reporter zebrafish
    • Perz-Edwards, A., Hardison, N. L. & Linney, E. Retinoic acid-mediated gene expression in transgenic reporter zebrafish. Dev. Biol. 229, 89-101 (2001).
    • (2001) Dev. Biol. , vol.229 , pp. 89-101
    • Perz-Edwards, A.1    Hardison, N.L.2    Linney, E.3
  • 88
    • 84876294515 scopus 로고    scopus 로고
    • Visualization of an endogenous retinoic acid gradient across embryonic development
    • Shimozono, S., Iimura, T., Kitaguchi, T., Higashijima, S. & Miyawaki, A. Visualization of an endogenous retinoic acid gradient across embryonic development. Nature 496, 363-366 (2013).
    • (2013) Nature , vol.496 , pp. 363-366
    • Shimozono, S.1    Iimura, T.2    Kitaguchi, T.3    Higashijima, S.4    Miyawaki, A.5
  • 89
    • 44949239539 scopus 로고    scopus 로고
    • Retinoic acid controls heart anteroposterior patterning by down-regulating isl1 through the fgf8 pathway
    • Sirbu, I. O., Zhao, X. & Duester, G. Retinoic acid controls heart anteroposterior patterning by down-regulating Isl1 through the Fgf8 pathway. Dev. Dyn. 237, 1627-1635 (2008).
    • (2008) Dev. Dyn. , vol.237 , pp. 1627-1635
    • Sirbu, I.O.1    Zhao, X.2    Duester, G.3
  • 90
    • 0141862018 scopus 로고    scopus 로고
    • Opposing fgf and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension
    • Diez del Corral, R. et al. Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron 40, 65-79 (2003).
    • (2003) Neuron , vol.40 , pp. 65-79
    • Diez Del Corral, R.1
  • 91
    • 0033786946 scopus 로고    scopus 로고
    • Opposing ra and fgf signals control proximodistal vertebrate limb development through regulation of meis genes
    • Mercader, N. et al. Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. Development 127, 3961-3970 (2000).
    • (2000) Development , vol.127 , pp. 3961-3970
    • Mercader, N.1
  • 92
    • 79957626589 scopus 로고    scopus 로고
    • Diffusible signals, not autonomous mechanisms, determine the main proximodistal limb subdivision
    • Rosello-Diez, A., Ros, M. A. & Torres, M. Diffusible signals, not autonomous mechanisms, determine the main proximodistal limb subdivision. Science 332, 1086-1088 (2011).
    • (2011) Science , vol.332 , pp. 1086-1088
    • Rosello-Diez, A.1    Ros, M.A.2    Torres, M.3
  • 93
    • 79952078840 scopus 로고    scopus 로고
    • Origins of cdx1 regulatory elements suggest roles in vertebrate evolution
    • Gaunt, S. J. & Paul, Y. L. Origins of Cdx1 regulatory elements suggest roles in vertebrate evolution. Int. J. Dev. Biol. 55, 93-98 (2011).
    • (2011) Int. J. Dev. Biol. , vol.55 , pp. 93-98
    • Gaunt, S.J.1    Paul, Y.L.2
  • 94
    • 84890859261 scopus 로고    scopus 로고
    • Region-specific regulation of posterior axial elongation during vertebrate embryogenesis
    • Neijts, R., Simmini, S., Giuliani, F., van Rooijen, C. & Deschamps, J. Region-specific regulation of posterior axial elongation during vertebrate embryogenesis. Dev. Dyn. 243, 88-98 (2014).
    • (2014) Dev. Dyn. , vol.243 , pp. 88-98
    • Neijts, R.1    Simmini, S.2    Giuliani, F.3    Van Rooijen, C.4    Deschamps, J.5
  • 95
    • 84880802221 scopus 로고    scopus 로고
    • Fgf signalling regulates chromatin organisation during neural differentiation via mechanisms that can be uncoupled from transcription
    • Patel, N. S. et al. FGF signalling regulates chromatin organisation during neural differentiation via mechanisms that can be uncoupled from transcription. PLoS Genet. 9, e1003614 (2013).
    • (2013) PLoS Genet. , vol.9 , pp. e1003614
    • Patel, N.S.1
  • 96
    • 0030113685 scopus 로고    scopus 로고
    • Vitamin a-deficient quail embryos have half a hindbrain and other neural defects
    • Maden, M., Gale, E., Kostetskii, I. & Zile, M. H. Vitamin A-deficient quail embryos have half a hindbrain and other neural defects. Curr. Biol. 6, 417-426 (1996).
    • (1996) Curr. Biol. , vol.6 , pp. 417-426
    • Maden, M.1    Gale, E.2    Kostetskii, I.3    Zile, M.H.4
  • 98
    • 0034655726 scopus 로고    scopus 로고
    • Vitamin a deficiency results in the dose-dependent acquisition of anterior character and shortening of the caudal hindbrain of the rat embryo
    • White, J. C., Highland, M., Kaiser, M. & Clagett-Dame, M. Vitamin A deficiency results in the dose-dependent acquisition of anterior character and shortening of the caudal hindbrain of the rat embryo. Dev. Biol. 220, 263-284 (2000).
    • (2000) Dev. Biol. , vol.220 , pp. 263-284
    • White, J.C.1    Highland, M.2    Kaiser, M.3    Clagett-Dame, M.4
  • 99
    • 6944232182 scopus 로고    scopus 로고
    • Vhnf1 integrates global ra patterning and local fgf signals to direct posterior hindbrain development in zebrafish
    • Hernandez, R. E., Rikhof, H. A., Bachmann, R. & Moens, C. B. vhnf1 integrates global RA patterning and local FGF signals to direct posterior hindbrain development in zebrafish. Development 131, 4511-4520 (2004).
    • (2004) Development , vol.131 , pp. 4511-4520
    • Hernandez, R.E.1    Rikhof, H.A.2    Bachmann, R.3    Moens, C.B.4
  • 100
    • 21244494831 scopus 로고    scopus 로고
    • Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression
    • Sirbu, I. O., Gresh, L., Barra, J. & Duester, G. Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression. Development 132, 2611-2622 (2005).
    • (2005) Development , vol.132 , pp. 2611-2622
    • Sirbu, I.O.1    Gresh, L.2    Barra, J.3    Duester, G.4
  • 101
    • 67651008230 scopus 로고    scopus 로고
    • Effect of retinoic acid signaling on wnt/α-catenin and fgf signaling during body axis extension
    • Zhao, X. & Duester, G. Effect of retinoic acid signaling on Wnt/α-catenin and FGF signaling during body axis extension. Gene Expr. Patterns 9, 430-435 (2009).
    • (2009) Gene Expr. Patterns , vol.9 , pp. 430-435
    • Zhao, X.1    Duester, G.2
  • 102
    • 33846034327 scopus 로고    scopus 로고
    • Cdx-hox code controls competence for responding to fgfs and retinoic acid in zebrafish neural tissue
    • Shimizu, T., Bae, Y. K. & Hibi, M. Cdx-Hox code controls competence for responding to Fgfs and retinoic acid in zebrafish neural tissue. Development 133, 4709-4719 (2006).
    • (2006) Development , vol.133 , pp. 4709-4719
    • Shimizu, T.1    Bae, Y.K.2    Hibi, M.3
  • 103
    • 34250804728 scopus 로고    scopus 로고
    • Repression of the hindbrain developmental program by cdx factors is required for the specification of the vertebrate spinal cord
    • Skromne, I., Thorsen, D., Hale, M., Prince, V. E. & Ho, R. K. Repression of the hindbrain developmental program by Cdx factors is required for the specification of the vertebrate spinal cord. Development 134, 2147-2158 (2007).
    • (2007) Development , vol.134 , pp. 2147-2158
    • Skromne, I.1    Thorsen, D.2    Hale, M.3    Prince, V.E.4    Ho, R.K.5
  • 104
    • 51449111098 scopus 로고    scopus 로고
    • Combinatorial signalling controls neurogenin2 expression at the onset of spinal neurogenesis
    • Ribes, V. et al. Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis. Dev. Biol. 321, 470-481 (2008).
    • (2008) Dev. Biol. , vol.321 , pp. 470-481
    • Ribes, V.1
  • 105
    • 84876928318 scopus 로고    scopus 로고
    • Soxb1-driven transcriptional network underlies neural-specific interpretation of morphogen signals
    • Oosterveen, T. et al. SoxB1-driven transcriptional network underlies neural-specific interpretation of morphogen signals. Proc. Natl Acad. Sci. USA 110, 7330-7335 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 7330-7335
    • Oosterveen, T.1
  • 106
    • 0034660462 scopus 로고    scopus 로고
    • Retinoic acid in the formation of the dorsoventral retina and its central projections
    • Wagner, E., McCaffery, P. & Dräger, U. C. Retinoic acid in the formation of the dorsoventral retina and its central projections. Dev. Biol. 222, 460-470 (2000).
    • (2000) Dev. Biol. , vol.222 , pp. 460-470
    • Wagner, E.1    McCaffery, P.2    Dräger, U.C.3
  • 107
    • 67149129951 scopus 로고    scopus 로고
    • Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: Aldh1a and retinoic acid signaling in vertebrate genomes
    • Canestro, C., Catchen, J. M., Rodriguez-Mari, A., Yokoi, H. & Postlethwait, J. H. Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes. PLoS Genet. 5, e1000496 (2009).
    • (2009) PLoS Genet. , vol.5 , pp. e1000496
    • Canestro, C.1    Catchen, J.M.2    Rodriguez-Mari, A.3    Yokoi, H.4    Postlethwait, J.H.5
  • 108
    • 28044449713 scopus 로고    scopus 로고
    • Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells
    • Matt, N. et al. Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells. Development 132, 4789-4800 (2005).
    • (2005) Development , vol.132 , pp. 4789-4800
    • Matt, N.1
  • 109
    • 33745093456 scopus 로고    scopus 로고
    • Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning
    • Molotkov, A., Molotkova, N. & Duester, G. Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. Development 133, 1901-1910 (2006).
    • (2006) Development , vol.133 , pp. 1901-1910
    • Molotkov, A.1    Molotkova, N.2    Duester, G.3
  • 110
    • 84855337631 scopus 로고    scopus 로고
    • Zebrafish model of axenfeld-rieger syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development
    • Bohnsack, B. L., Kasprick, D. S., Kish, P. E., Goldman, D. & Kahana, A. A. Zebrafish model of Axenfeld-Rieger syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development. Invest. Ophthalmol. Vis. Sci. 53, 7-22 (2012).
    • (2012) Invest. Ophthalmol. Vis. Sci. , vol.53 , pp. 7-22
    • Bohnsack, B.L.1    Kasprick, D.S.2    Kish, P.E.3    Goldman, D.4    Kahana, A.A.5
  • 111
    • 77649181111 scopus 로고    scopus 로고
    • Retinoic acid signaling in perioptic mesenchyme represses wnt signaling via induction of pitx2 and dkk2
    • Kumar, S. & Duester, G. Retinoic acid signaling in perioptic mesenchyme represses Wnt signaling via induction of Pitx2 and Dkk2. Dev. Biol. 340, 67-74 (2010).
    • (2010) Dev. Biol. , vol.340 , pp. 67-74
    • Kumar, S.1    Duester, G.2
  • 112
    • 33847037941 scopus 로고    scopus 로고
    • Retinoids control anterior and dorsal properties in the developing forebrain
    • Halilagic, A. et al. Retinoids control anterior and dorsal properties in the developing forebrain. Dev. Biol. 303, 362-375 (2007).
    • (2007) Dev. Biol. , vol.303 , pp. 362-375
    • Halilagic, A.1
  • 113
    • 33847390216 scopus 로고    scopus 로고
    • Role of retinoic acid during forebrain development begins late when raldh3 generates retinoic acid in the ventral subventricular zone
    • Molotkova, N., Molotkov, A. & Duester, G. Role of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zone. Dev. Biol. 303, 601-610 (2007).
    • (2007) Dev. Biol. , vol.303 , pp. 601-610
    • Molotkova, N.1    Molotkov, A.2    Duester, G.3
  • 114
    • 0031474157 scopus 로고    scopus 로고
    • Regulation of dopaminergic pathways by retinoids: Activation of the d2 receptor promoter by members of the retinoic acid receptor retinoid x receptor family
    • Samad, T. A., Krezel, W., Chambon, P. & Borrelli, E. Regulation of dopaminergic pathways by retinoids: activation of the D2 receptor promoter by members of the retinoic acid receptor retinoid X receptor family. Proc. Natl Acad. Sci. USA 94, 14349-14354 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 14349-14354
    • Samad, T.A.1    Krezel, W.2    Chambon, P.3    Borrelli, E.4
  • 115
    • 79955509033 scopus 로고    scopus 로고
    • Retinoic acid functions as a key gabaergic differentiation signal in the basal ganglia
    • Chatzi, C., Brade, T. & Duester, G. Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. PLoS Biol. 9, e1000609 (2011).
    • (2011) PLoS Biol. , vol.9 , pp. e1000609
    • Chatzi, C.1    Brade, T.2    Duester, G.3
  • 116
    • 70350338215 scopus 로고    scopus 로고
    • Retinoic acid from the meninges regulates cortical neuron generation
    • Siegenthaler, J. A. et al. Retinoic acid from the meninges regulates cortical neuron generation. Cell 139, 597-609 (2009).
    • (2009) Cell , vol.139 , pp. 597-609
    • Siegenthaler, J.A.1
  • 117
    • 74049150745 scopus 로고    scopus 로고
    • Retinoic acid receptors exhibit cell-Autonomous functions in cranial neural crest cells
    • Dupe, V. & Pellerin, I. Retinoic acid receptors exhibit cell-Autonomous functions in cranial neural crest cells. Dev. Dyn. 238, 2701-2711 (2009).
    • (2009) Dev. Dyn. , vol.238 , pp. 2701-2711
    • Dupe, V.1    Pellerin, I.2
  • 118
    • 0028175195 scopus 로고
    • Rxr? Mutant mice establish a genetic basis for vitamin a signaling in heart morphogenesis
    • Sucov, H. M. et al. RXR? mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev. 8, 1007-1018 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 1007-1018
    • Sucov, H.M.1
  • 119
    • 29444451293 scopus 로고    scopus 로고
    • Epicardial retinoid x receptor ? Is required for myocardial growth and coronary artery formation
    • Merki, E. et al. Epicardial retinoid X receptor ? is required for myocardial growth and coronary artery formation. Proc. Natl Acad. Sci. USA 102, 18455-18460 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 18455-18460
    • Merki, E.1
  • 120
    • 78650734178 scopus 로고    scopus 로고
    • Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial igf2
    • Brade, T. et al. Retinoic acid stimulates myocardial expansion by induction of hepatic erythropoietin which activates epicardial Igf2. Development 138, 139-148 (2011).
    • (2011) Development , vol.138 , pp. 139-148
    • Brade, T.1
  • 121
    • 0035312526 scopus 로고    scopus 로고
    • A developmental transition in definitive erythropoiesis: Erythropoietin expression is sequentially regulated by retinoic acid receptors and hnf4
    • Makita, T. et al. A developmental transition in definitive erythropoiesis: erythropoietin expression is sequentially regulated by retinoic acid receptors and HNF4. Genes Dev. 15, 889-901 (2001).
    • (2001) Genes Dev. , vol.15 , pp. 889-901
    • Makita, T.1
  • 122
    • 79955424835 scopus 로고    scopus 로고
    • Igf signaling directs ventricular cardiomyocyte proliferation during embryonic heart development
    • Li, P. et al. IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development 138, 1795-1805 (2011).
    • (2011) Development , vol.138 , pp. 1795-1805
    • Li, P.1
  • 123
    • 33644521570 scopus 로고    scopus 로고
    • Retinoic acid regulates sex-specific timing of meiotic initiation in mice
    • Koubova, J. et al. Retinoic acid regulates sex-specific timing of meiotic initiation in mice. Proc. Natl Acad. Sci. USA 103, 2474-2479 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 2474-2479
    • Koubova, J.1
  • 124
    • 33646198340 scopus 로고    scopus 로고
    • Retinoid signaling determines germ cell fate in mice
    • Bowles, J. et al. Retinoid signaling determines germ cell fate in mice. Science 312, 596-600 (2006).
    • (2006) Science , vol.312 , pp. 596-600
    • Bowles, J.1
  • 125
    • 78651353059 scopus 로고    scopus 로고
    • Sex-specific timing of meiotic initiation is regulated by cyp26b1 independent of retinoic acid signaling
    • Kumar, S. et al. Sex-specific timing of meiotic initiation is regulated by Cyp26b1 independent of retinoic acid signaling. Nature Commun. 2, 151 (2011).
    • (2011) Nature Commun. , vol.2 , pp. 151
    • Kumar, S.1
  • 126
    • 84884137354 scopus 로고    scopus 로고
    • Resolving molecular events in the regulation of meiosis in male and female germ cells
    • Kumar, S., Cunningham, T. J. & Duester, G. Resolving molecular events in the regulation of meiosis in male and female germ cells. Sci. Signal. 6, e25 (2013).
    • (2013) Sci. Signal. , vol.6 , pp. e25
    • Kumar, S.1    Cunningham, T.J.2    Duester, G.3
  • 127
    • 77952317137 scopus 로고    scopus 로고
    • Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development
    • Naillat, F. et al. Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum. Mol. Genet. 19, 1539-1550 (2010).
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 1539-1550
    • Naillat, F.1
  • 128
    • 84902242400 scopus 로고    scopus 로고
    • Progesterone regulates chicken embryonic germ cell meiotic initiation independent of retinoic acid signaling
    • Mi, Y., He, B., Li, J. & Zhang, C. Progesterone regulates chicken embryonic germ cell meiotic initiation independent of retinoic acid signaling. Theriogenology 82, 195-203 (2014).
    • (2014) Theriogenology , vol.82 , pp. 195-203
    • Mi, Y.1    He, B.2    Li, J.3    Zhang, C.4
  • 129
    • 12244265506 scopus 로고    scopus 로고
    • Retinoic acid signaling restricts the cardiac progenitor pool
    • Keegan, B. R., Feldman, J. L., Begemann, G., Ingham, P. W. & Yelon, D. Retinoic acid signaling restricts the cardiac progenitor pool. Science 307, 247-249 (2005).
    • (2005) Science , vol.307 , pp. 247-249
    • Keegan, B.R.1    Feldman, J.L.2    Begemann, G.3    Ingham, P.W.4    Yelon, D.5
  • 130
    • 42949174176 scopus 로고    scopus 로고
    • Retinoic acid deficiency alters second heart field formation
    • Ryckebusch, L. et al. Retinoic acid deficiency alters second heart field formation. Proc. Natl Acad. Sci. USA 105, 2913-2918 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 2913-2918
    • Ryckebusch, L.1
  • 131
    • 0344630320 scopus 로고    scopus 로고
    • A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment
    • Dupé, V. et al. A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment. Proc. Natl Acad. Sci. USA 100, 14036-14041 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 14036-14041
    • Dupé, V.1
  • 132
    • 0034921830 scopus 로고    scopus 로고
    • Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining fgf8 and shh
    • Schneider, R. A., Hu, D., Rubenstein, J. L. R., Maden, M. & Helms, J. A. Local retinoid signaling coordinates forebrain and facial morphogenesis by maintaining FGF8 and SHH. Development 128, 2755-2767 (2001).
    • (2001) Development , vol.128 , pp. 2755-2767
    • Schneider, R.A.1    Hu, D.2    Rubenstein, J.L.R.3    Maden, M.4    Helms, J.A.5
  • 133
    • 34548562240 scopus 로고    scopus 로고
    • Inhibition of tgf? Signaling by endogenous retinoic acid is essential for primary lung bud induction
    • Chen, F. et al. Inhibition of Tgf? signaling by endogenous retinoic acid is essential for primary lung bud induction. Development 134, 2969-2979 (2007).
    • (2007) Development , vol.134 , pp. 2969-2979
    • Chen, F.1
  • 134
    • 77953183186 scopus 로고    scopus 로고
    • A retinoic acid-dependent network in the foregut controls formation of the mouse lung primordium
    • Chen, F. et al. A retinoic acid-dependent network in the foregut controls formation of the mouse lung primordium. J. Clin. Invest. 120, 2040-2048 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 2040-2048
    • Chen, F.1
  • 135
    • 64549100829 scopus 로고    scopus 로고
    • Early mouse caudal development relies on crosstalk between retinoic acid shh and fgf signalling pathways
    • Ribes, V., Le Roux, I., Rhinn, M., Schuhbaur, B. & Dolle, P. Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways. Development 136, 665-676 (2009).
    • (2009) Development , vol.136 , pp. 665-676
    • Ribes, V.1    Le Roux, I.2    Rhinn, M.3    Schuhbaur, B.4    Dolle, P.5
  • 136
    • 84877707375 scopus 로고    scopus 로고
    • One-step generation of mice carrying mutations in multiple genes by crispr/cas-mediated genome engineering
    • Wang, H. et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153, 910-918 (2013).
    • (2013) Cell , vol.153 , pp. 910-918
    • Wang, H.1
  • 137
    • 64549139013 scopus 로고    scopus 로고
    • Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system
    • Strate, I., Min, T. H., Iliev, D. & Pera, E. M. Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system. Development 136, 461-472 (2009).
    • (2009) Development , vol.136 , pp. 461-472
    • Strate, I.1    Min, T.H.2    Iliev, D.3    Pera, E.M.4
  • 138
    • 80053620782 scopus 로고    scopus 로고
    • Involvement of retinol dehydrogenase 10 in embryonic patterning and rescue of its loss of function by maternal retinaldehyde treatment
    • Rhinn, M., Schuhbaur, B., Niederreither, K. & Dolle, P. Involvement of retinol dehydrogenase 10 in embryonic patterning and rescue of its loss of function by maternal retinaldehyde treatment. Proc. Natl Acad. Sci. USA 108, 16687-16692 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 16687-16692
    • Rhinn, M.1    Schuhbaur, B.2    Niederreither, K.3    Dolle, P.4
  • 139
    • 0036337341 scopus 로고    scopus 로고
    • Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of raldh2 null mutant mice
    • Mic, F. A., Haselbeck, R. J., Cuenca, A. E. & Duester, G. Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. Development 129, 2271-2282 (2002).
    • (2002) Development , vol.129 , pp. 2271-2282
    • Mic, F.A.1    Haselbeck, R.J.2    Cuenca, A.E.3    Duester, G.4
  • 140
    • 24044435550 scopus 로고    scopus 로고
    • The zebrafish retinol dehydrogenase, rdh1l, is essential for intestinal development and is regulated by the tumor suppressor adenomatous polyposis coli
    • Nadauld, L. D., Shelton, D. N., Chidester, S., Yost, H. J. & Jones, D. A. The zebrafish retinol dehydrogenase, rdh1l, is essential for intestinal development and is regulated by the tumor suppressor adenomatous polyposis coli. J. Biol. Chem. 280, 30490-30495 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 30490-30495
    • Nadauld, L.D.1    Shelton, D.N.2    Chidester, S.3    Yost, H.J.4    Jones, D.A.5
  • 141
    • 0037706864 scopus 로고    scopus 로고
    • Targeted disruption of aldh1a1 (raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina
    • Fan, X. et al. Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina. Mol. Cell. Biol. 23, 4637-4648 (2003).
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4637-4648
    • Fan, X.1
  • 142
    • 33846545127 scopus 로고    scopus 로고
    • Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development
    • Hernandez, R. E., Putzke, A. P., Myers, J. P., Margaretha, L. & Moens, C. B. Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development. Development 134, 177-187 (2007).
    • (2007) Development , vol.134 , pp. 177-187
    • Hernandez, R.E.1    Putzke, A.P.2    Myers, J.P.3    Margaretha, L.4    Moens, C.B.5
  • 143
    • 37249079634 scopus 로고    scopus 로고
    • Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo
    • White, R. J., Nie, Q., Lander, A. D. & Schilling, T. F. Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol. 5, e304 (2007).
    • (2007) PLoS Biol. , vol.5 , pp. e304
    • White, R.J.1    Nie, Q.2    Lander, A.D.3    Schilling, T.F.4
  • 144
    • 0033603209 scopus 로고    scopus 로고
    • A sonic hedgehog-independent, retinoid-Activated pathway of neurogenesis in the ventral spinal cord
    • Pierani, A., Brenner-Morton, S., Chiang, C. & Jessell, T. M. A sonic hedgehog-independent, retinoid-Activated pathway of neurogenesis in the ventral spinal cord. Cell 97, 903-915 (1999).
    • (1999) Cell , vol.97 , pp. 903-915
    • Pierani, A.1    Brenner-Morton, S.2    Chiang, C.3    Jessell, T.M.4
  • 145
    • 34548498595 scopus 로고    scopus 로고
    • Direct regulation of vHnf1 by retinoic acid signaling and MAF-related factors in the neural tube
    • Pouilhe, M., Gilardi-Hebenstreit, P., Desmarquet-Trin Dinh, C. & Charnay, P. Direct regulation of vHnf1 by retinoic acid signaling and MAF-related factors in the neural tube. Dev. Biol. 309, 344-357 (2007).
    • (2007) Dev. Biol. , vol.309 , pp. 344-357
    • Pouilhe, M.1    Gilardi-Hebenstreit, P.2    Desmarquet-Trin Dinh, C.3    Charnay, P.4
  • 146
    • 0026794938 scopus 로고
    • Identification of a retinoic acid responsive enhancer 3? of the murine homebox gene hox-1.6
    • Langston, A. W. & Gudas, L. J. Identification of a retinoic acid responsive enhancer 3? of the murine homebox gene Hox-1.6. Mech. Dev. 38, 217-228 (1992).
    • (1992) Mech. Dev. , vol.38 , pp. 217-228
    • Langston, A.W.1    Gudas, L.J.2
  • 147
    • 0031040738 scopus 로고    scopus 로고
    • In vivo functional analysis of the hoxa-1 3? Retinoic acid response element (3?rare)
    • Dupé, V. et al. In vivo functional analysis of the Hoxa-1 3? retinoic acid response element (3?RARE). Development 124, 399-410 (1997).
    • (1997) Development , vol.124 , pp. 399-410
    • Dupé, V.1
  • 148
    • 0028065238 scopus 로고
    • A conserved retinoic acid response element required for early expression of the homeobox gene hoxb-1
    • Marshall, H. et al. A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1. Nature 370, 567-571 (1994).
    • (1994) Nature , vol.370 , pp. 567-571
    • Marshall, H.1
  • 149
    • 0036194621 scopus 로고    scopus 로고
    • Analysis of two distinct retinoic acid response elements in the homeobox gene hoxb1 in transgenic mice
    • Huang, D. Y., Chen, S. M. W. & Gudas, L. J. Analysis of two distinct retinoic acid response elements in the homeobox gene Hoxb1 in transgenic mice. Dev. Dyn. 223, 353-370 (2002).
    • (2002) Dev. Dyn. , vol.223 , pp. 353-370
    • Huang, D.Y.1    Chen, S.M.W.2    Gudas, L.J.3
  • 150
    • 0042329183 scopus 로고    scopus 로고
    • A position-dependent organisation of retinoid response elements is conserved in the vertebrate hox clusters
    • Mainguy, G. et al. A position-dependent organisation of retinoid response elements is conserved in the vertebrate Hox clusters. Trends Genet. 19, 476-479 (2003).
    • (2003) Trends Genet. , vol.19 , pp. 476-479
    • Mainguy, G.1
  • 151
    • 0031835078 scopus 로고    scopus 로고
    • Expression of the murine hoxa4 gene requires both autoregulation and a conserved retinoic acid response element
    • Packer, A. I., Crotty, D. A., Elwell, V. A. & Wolgemuth, D. J. Expression of the murine Hoxa4 gene requires both autoregulation and a conserved retinoic acid response element. Development 125, 1991-1998 (1998).
    • (1998) Development , vol.125 , pp. 1991-1998
    • Packer, A.I.1    Crotty, D.A.2    Elwell, V.A.3    Wolgemuth, D.J.4
  • 152
    • 84895427966 scopus 로고    scopus 로고
    • Long-range regulation by shared retinoic acid response elements modulates dynamic expression of posterior Hoxb genes in CNS development
    • Ahn, Y., Mullan, H. E. & Krumlauf, R. Long-range regulation by shared retinoic acid response elements modulates dynamic expression of posterior Hoxb genes in CNS development. Dev. Biol. 388, 134-144 (2014).
    • (2014) Dev. Biol. , vol.388 , pp. 134-144
    • Ahn, Y.1    Mullan, H.E.2    Krumlauf, R.3
  • 153
    • 0032126768 scopus 로고    scopus 로고
    • Initiation of rhombomeric hoxb4 expression requires induction by somites and a retinoid pathway
    • Gould, A., Itasaki, N. & Krumlauf, R. Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway. Neuron 21, 39-51 (1998).
    • (1998) Neuron , vol.21 , pp. 39-51
    • Gould, A.1    Itasaki, N.2    Krumlauf, R.3
  • 154
    • 0343035601 scopus 로고    scopus 로고
    • Elements both 5? and 3? to the murine hoxd4 gene establish anterior borders of expression in mesoderm and neurectoderm
    • Zhang, F. et al. Elements both 5? and 3? to the murine Hoxd4 gene establish anterior borders of expression in mesoderm and neurectoderm. Mech. Dev. 67, 49-58 (1997).
    • (1997) Mech. Dev. , vol.67 , pp. 49-58
    • Zhang, F.1
  • 155
    • 0037362117 scopus 로고    scopus 로고
    • The role of a retinoic acid response element in establishing the anterior neural expression border of hoxd4 transgenes
    • Nolte, C., Amores, A., Kovács, E. N., Postlethwait, J. & Featherstone, M. The role of a retinoic acid response element in establishing the anterior neural expression border of Hoxd4 transgenes. Mech. Dev. 120, 325-335 (2003).
    • (2003) Mech. Dev. , vol.120 , pp. 325-335
    • Nolte, C.1    Amores, A.2    Kovács, E.N.3    Postlethwait, J.4    Featherstone, M.5
  • 156
    • 0037439084 scopus 로고    scopus 로고
    • Retinoids regulate the anterior expression boundaries of 5? Hoxb genes in posterior hindbrain
    • Oosterveen, T. et al. Retinoids regulate the anterior expression boundaries of 5? Hoxb genes in posterior hindbrain. EMBO J. 22, 262-269 (2003).
    • (2003) EMBO J. , vol.22 , pp. 262-269
    • Oosterveen, T.1
  • 157
    • 0034704133 scopus 로고    scopus 로고
    • Multiple regulatory elements in the murine stromelysin-3 promoter. Evidence for direct control by ccaat/enhancer-binding protein ? and thyroid and retinoid receptors
    • Ludwig, M. G., Basset, P. & Anglard, P. Multiple regulatory elements in the murine stromelysin-3 promoter. Evidence for direct control by CCAAT/enhancer-binding protein ? and thyroid and retinoid receptors. J. Biol. Chem. 275, 39981-39990 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 39981-39990
    • Ludwig, M.G.1    Basset, P.2    Anglard, P.3
  • 158
    • 0026093858 scopus 로고
    • Developmental analysis of the retinoic acid-inducible rar-2 promoter in transgenic animals
    • Mendelsohn, C., Ruberte, E., LeMeur, M., Morriss-Kay, G. & Chambon, P. Developmental analysis of the retinoic acid-inducible RAR-2 promoter in transgenic animals. Development 113, 723-734 (1991).
    • (1991) Development , vol.113 , pp. 723-734
    • Mendelsohn, C.1    Ruberte, E.2    Lemeur, M.3    Morriss-Kay, G.4    Chambon, P.5
  • 159
    • 0030051022 scopus 로고    scopus 로고
    • Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid x receptor response element) in the mouse tissue transglutaminase gene promoter
    • Nagy, L. et al. Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter. J. Biol. Chem. 271, 4355-4365 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 4355-4365
    • Nagy, L.1


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