vhnf1 integrates global RA patterning and local FGF signals to direct posterior hindbrain development in zebrafish

Development

Volumn 131, Issue 18, 2004, Pages 4511-4520

  Hernandez, Rafael E ^a,b   Rikhof, Holly A ^a   Bachmann, Ruxandra ^a,c   Moens, Cecilia B ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Fibroblast growth factor; Hindbrain; hox; mafB; Retinoic acid; Rhombomere; valentino; vhnf1

Indexed keywords

FIBROBLAST GROWTH FACTOR; HOX PROTEIN; NUCLEAR FACTOR I; RETINOIC ACID; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CELL FATE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; EMBRYO; GENE ACTIVATION; MORPHOGENESIS; NEUROMERE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; ZEBRA FISH;

ANIMALS; BODY PATTERNING; DNA-BINDING PROTEINS; EMBRYO, NONMAMMALIAN; EPHRIN-B2; FIBROBLAST GROWTH FACTOR 3; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HOMEODOMAIN PROTEINS; MAFB TRANSCRIPTION FACTOR; MOSAICISM; MUTATION; NERVE TISSUE PROTEINS; RHOMBENCEPHALON; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRETINOIN; ZEBRAFISH; ZEBRAFISH PROTEINS;

ANIMALIA; DANIO RERIO; VERTEBRATA;

EID: 6944232182     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.01297     Document Type: Article

References (54)

1. Agarwal, C., Chandraratna, R. A., Johnson, A. T., Rorke, E. A. and Eckert, R. L. (1996). AGN193109 is a highly effective antagonist of retinoid action in human ectocervical epithelial cells. J. Biol. Chem. 271, 12209-12212.
2. Alexandre, D., Clarke, J. D., Oxtoby, E., Yan, Y. L., Jowett, T. and Holder, N. (1996). Ectopic expression of Hoxa-1 in the zebrafish alters the fate of the mandibular arch neural crest and phenocopies a retinoic acid-induced phenotype. Development 122 735-746.
3. Begemann, G., Schilling, T. F., Rauch, G. J., Geisler, R. and Ingham, P. W. (2001). The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development 128, 3081-3094.
4. Coffinier, C., Thepot, D., Babinet, C., Yaniv, M. and Barra, J. (1999). Essential role for the homeoprotein vHNF1/HNF1beta in visceral endoderm differentiation. Development 126, 4785-4794.
5. Cooke, J., Moens, C., Roth, L., Durbin, L., Shiomi, K., Brennan, C., Kimmel, C., Wilson, S. and Holder, N. (2001). Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain. Development 128, 571-580.
6. Cordes, S. P. and Barsh, G. S. (1994). The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell 79, 1025-1034.
7. Dupe, V. and Lumsden, A. (2001). Hindbrain patterning involves graded responses to retinoic acid signalling. Development 128, 2199-2208.
8. Dupe, V., Davenne, M., Brocard, J., Dolle, P., Mark, M., Dierich, A., Chambon, P. and Rijli, F. M. (1997). In vivo functional analysis of the Hoxa-1 3′ retinoic acid response element (3′ RARE). Development 124, 399-410.
9. Eichmann, A., Grapin-Botton, A., Kelly, L., Graf, T., Le Douarin, N. M. and Sieweke, M. (1997). The expression pattern of the mafB/kr gene in birds and mice reveals that the kreisler phenotype does not represent a null mutant. Mech. Dev. 65, 111-122.
10. Furthauer, M., Thisse, B. and Thisse, C. (1999). Three different noggin genes antagonize the activity of bone morphogenetic proteins in the zebrafish embryo. Dev. Biol. 214, 181-196.
11. Gaufo, G. O., Thomas, K. R. and Capecchi, M. R. (2003). Hox3 genes coordinate mechanisms of genefic suppression and activation in the generation of branchial and somatic motoneurons. Development 130, 5191-5201.
12. Gavalas, A. and Krumlauf, R. (2000). Retinoid signalling and hindbrain patterning. Curr. Opin. Genet. Dev. 10 380-386.
13. Geldmacher-Voss, B., Reugels, A. M., Pauls, S. and Campos-Ortega, J. A. (2003). A 90-degree rotation of the mitotic spindle changes the orientation of mitoses of zebrafish neuroepithelial cells. Development 130, 3767-3780.
14. Giudicelli, F., Gilardi-Hebenstreit, P., Mechta-Grigoriou, F., Poquet, C. and Charnay, P. (2003). Novel activities of Mafb underlie its dual role in hindbrain segmentation and regional specification. Dev. Biol. 253, 150-162.
15. Gould, A., Itasaki, N. and Krumlauf, R. (1998). Initiation of rhombomeric Hoxb4 expression requires induction by somites and a retinoid pathway. Neuron 21, 39-51.
16. Grandel, H., Lun, K., Rauch, G. J., Rhinn, M., Piotrowski, T., Houart, C., Sordino, P., Kuchler, A. M., Schulte-Merker, S., Geisler, R. et al. (2002). Retinoic acid signalling in the zebrafish embryo is necessary during presegmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development 129, 2851-2865.
17. Guidato, S., Prin, F. and Guthrie, S. (2003). Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3. Development 130 2981-2996.
18. Hamada, M., Moriguchi, T., Yokomizo, T., Morito, N., Zhang, C. and Takahashi, S. (2003). The mouse mafB 5′-upstream fragment directs gene expression in myelomonocytic cells, differentiated macrophages and the ventral spinal cord in transgenic mice. J. Biochem. 134, 203-210.
19. Hatta, K. (1992). Role of the floor plate in axonal patterning in the zebrafish CNS. Neuron 9, 629-642.
20. Johnson, A. T., Klein, E. S., Gillett, S. J., Wang, L., Song, T. K., Pino, M. E. and Chandraratna, R. A. (1995). Synthesis and characterization of a highly potent and effective antagonist of retinoic acid receptors. J. Med. Chem. 38, 4764-4767.
21. Kimmel, C. B., Warga, R. M. and Kane, D. A. (1994). Cell cycles and clonal strings during formation of the zebrafish central nervous system. Development 120, 265-276.
22. Lekven, A. C., Thorpe, C. J., Waxman, J. S. and Moon, R. T. (2001). Zebrafish wnt8 encodes two wnt8 proteins on a bicistronic transcript and is required for mesoderm and neurectoderm patterning. Dev. Cell 1, 103-114.
23. Linville, A., Gumusaneli, E., Chandraratna, R. A. and Schilling, T. F. (2004). Independent roles for retinoic acid in segmentation and neuronal differentiation in the zebrafish hindbrain. Dev. Biol. 270, 186-199.
24. Lumsden, A. and Krumlauf, R. (1996). Patterning the vertebrate neuraxis. Science 274, 1109-1115.
25. Manzanares, M., Bel-Vialar, S., Ariza-McNaughton, L., Ferretti, E., Marshall, H., Maconochie, M. M., Blasi, F. and Krumlauf, R. (2001). Independent regulation of initiation and maintenance phases of Hoxa3 expression in the vertebrate hindbrain involve auto- and cross-regulatory mechanisms. Development 128, 3595-3607.
26. Manzanares, M., Cordes, S., Ariza-McNaughton, L., Sadl, V., Maruthainar, K., Barsh, G. and Krumlauf, R. (1999a). Conserved and distinct roles of kreisler in regulation of the paralogous Hoxa3 and Hoxb3 genes. Development 126, 759-769.
27. Manzanares, M., Cordes, S., Kwan, C. T., Sham, M. H., Barsh, G. S. and Krumlauf, R. (1997). Segmental regulation of Hoxb-3 by kreisler. Nature 387, 191-195.
28. Manzanares, M., Nardelli, J., Gilardi-Hebenstreit, P., Marshall, H., Giudicelli, F., Martinez-Pastor, M. T., Krumlauf, R. and Charnay, P. (2002). Krox20 and kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain. EMBO J. 21, 365-376.
29. Manzanares, M., Trainor, P. A., Nonchev, S., Ariza-McNaughton, L., Brodie, J., Gould, A., Marshall, H., Morrison, A., Kwan, C. T., Sham, M. H. et al. (1999b). The role of kreisler in segmentation during hindbrain development. Dev. Biol. 211, 220-237.
30. Maroon, H., Walshe, J., Mahmood, R., Kiefer, P., Dickson, C. and Mason, I. (2002). Fgf3 and Fgf8 are required together for formation of the otic placode and vesicle. Development 129, 2099-2108.
31. Marshall, H., Studer, M., Popperl, H., Aparicio, S., Kuroiwa, A., Brenner, S. and Krumlauf, R. (1994). A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1. Nature 370, 567-571.
32. Maves, L., Jackman, W. and Kimmel, C. B. (2002). FGF3 and FGF8 mediate a rhombomere 4 signaling activity in the zebrafish hindbrain. Development 129, 3825-3837.
33. McKay, I. J., Muchamore, I., Krumlauf, R., Maden, M., Lumsden, A. and Lewis, J. (1994). The kreisler mouse: a hindbrain segmentation mutant that lacks two rhombomeres. Development 120 2199-2211.
34. Mellitzer, G., Xu, Q. and Wilkinson, D. G. (1999). Eph receptors and ephrins restrict cell intermingling and communication. Nature 400, 77-81.
35. Moens, C. B. and Fritz, A. (1999). Techniques in neural development. Methods Cell Biol. 59, 253-272.
36. Moens, C. B. and Prince, V. E. (2002). Constructing the hindbrain: insights from the zebrafish. Dev. Dyn. 224, 1-17.
37. Moens, C. B., Cordes, S. P., Giorgianni, M. W., Barsh, G. S. and Kimmel, C. B. (1998). Equivalence in the genetic control of hindbrain segmentation in fish and mouse. Development 125, 381-391.
38. Moens, C. B., Yan, Y. L., Appel, B., Force, A. G. and Kimmel, C. B. (1996). valentino: a zebrafish gene required for normal hindbrain segmentation. Development 122, 3981-3990.
39. Power, S. C. and Cereghini, S. (1996). Positive regulation of the vHNF1 promoter by the orphan receptors COUP-TF1/Ear3 and COUP-TFII/Arp1. Mol. Cell. Biol. 16, 778-791.
40. Powers, C. J., McLeskey, S. W. and Wellstein, A. (2000). Fibroblast growth factors, their receptors and signaling. Endocr. Relat. Cancer 7, 165-197.
41. Prince, V. E., Moens, C. B., Kimmel, C. B. and Ho, R. K. (1998). Zebrafish hox genes: expression in the hindbrain region of wild-type and mutants of the segmentation gene, valentino. Development 125, 393-406.
42. Reifers, F., Bohli, H., Walsh, E. C., Crossley, P, H., Stainier, D. Y. and Brand, M. (1998). Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125, 2381-2395.
43. Schneider-Maunoury, S., Seitanidou, T., Charnay, P. and Lumsden, A. (1997). Segmental and neuronal architecture of the hindbrain of Krox-20 mouse mutants. Development 124, 1215-1226.
44. Sun, Z. and Hopkins, N. (2001). vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain. Genes Dev. 15, 3217-3229.
45. Theil, T., Frain, M., Gilardi-Hebenstreit, P., Flenniken, A., Charnay, P. and Wilkinson, D. G. (1998). Segmental expression of the EphA4 (Sek-1) receptor tyrosine kinase in the hindbrain is under direct transcriptional control of Krox-20. Development 125, 443-452.
46. Umbhauer, M., Marshall, C. J., Mason, C. S., Old, R. W. and Smith, J. C. (1995). Mesoderm induction in Xenopus caused by activation of MAP kinase. Nature 376, 58-62.
47. Walshe, J., Maroon, H., McGonnell, I. M., Dickson, C. and Mason, I. (2002). Establishment of hindbrain segmental identity requires signaling by FGF3 and FGF8. Curr. Biol. 12, 1117-1123.
48. Waskiewicz, A. J., Rikhof, H. A., Hernandez, R. E. and Moens, C. B. (2001). Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning. Development 128, 4139-4151.
49. Waskiewicz, A. J., Rikhof, H. A. and Moens, C. B. (2002). Eliminating zebrafish pbx proteins reveals a hindbrain ground state. Dev. Cell 3, 723-733.
50. Wendling, O., Ghyselinck, N. B., Chambon, P. and Mark, M. (2001). Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning. Development 128, 2031-2038.
51. Wiellette, E. L. and Sive, H. (2003). vhnf1 and Fgf signals synergize to specify rhombomere identity in the zebrafish hindbrain. Development 130, 3821-3829.
52. Wilkinson, D. G., Bhatt, S., Cook, M., Boncinelli, E. and Krumlauf, R. (1989). Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain. Nature 341, 405-409.
53. Xu, Q., Mellitzer, G., Robinson, V. and Wilkinson, D. G. (1999). In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins. Nature 399, 267-271.
54. Zimmerman, L. B., De Jesus-Escobar, J. M. and Harland, R. M. (1996). The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86, 599-606.