-
2
-
-
65449151412
-
Therapies for hyperglycaemia-induced diabetic complications: From animal models to clinical trials
-
Calcutt NA, Cooper ME, Kern TS, Schmidt AM. Therapies for hyperglycaemia-induced diabetic complications: From animal models to clinical trials. Nat Rev Drug Discov. 2009;8:417-429.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 417-429
-
-
Calcutt, N.A.1
Cooper, M.E.2
Kern, T.S.3
Schmidt, A.M.4
-
3
-
-
0034628425
-
Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy
-
Lachin JM, Genuth S, Cleary P. Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy. N Engl J Med. 2000;342:381-389.
-
(2000)
N Engl J Med
, vol.342
, pp. 381-389
-
-
Lachin, J.M.1
Genuth, S.2
Cleary, P.3
-
4
-
-
0027385062
-
Daily vitamin E supplements improve metabolic control but not insulin secretion in elderly type II diabetic patients
-
Paolisso G, D'Amore A, Galzerano D, et al. Daily vitamin E supplements improve metabolic control but not insulin secretion in elderly type II diabetic patients. Diabetes Care. 1993;16:1433-1437.
-
(1993)
Diabetes Care
, vol.16
, pp. 1433-1437
-
-
Paolisso, G.1
D'Amore, A.2
Galzerano, D.3
-
5
-
-
84878687221
-
Endoplasmic reticulum is at the crossroads of autophagy, inflammation, and apoptosis signaling pathways and participates in the pathogenesis of diabetes mellitus
-
Su J, Zhou L, Kong X, et al. Endoplasmic reticulum is at the crossroads of autophagy, inflammation, and apoptosis signaling pathways and participates in the pathogenesis of diabetes mellitus. J Diabetes Res. 2013;2013:193461.
-
(2013)
J Diabetes Res
, vol.2013
, pp. 193461
-
-
Su, J.1
Zhou, L.2
Kong, X.3
-
6
-
-
34250753161
-
Cell death modalities: Classification and pathophysiological implications
-
Galluzzi L, Maiuri MC, Vitale I, et al. Cell death modalities: Classification and pathophysiological implications. Cell Death Differ. 2007;14:1237-1243.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1237-1243
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
-
7
-
-
0034920828
-
Nitric oxide synthesis and oxidative stress in the renal cortex of rats with diabetes mellitus
-
Ishii N, Patel KP, Lane PH, et al. Nitric oxide synthesis and oxidative stress in the renal cortex of rats with diabetes mellitus. J Am Soc Nephrol. 2001;12:1630-1639.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 1630-1639
-
-
Ishii, N.1
Patel, K.P.2
Lane, P.H.3
-
8
-
-
0344850195
-
Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: Role of nitric oxide synthase?
-
Du X, Stocklauser-Farber K, Rosen P. Generation of reactive oxygen intermediates, activation of NF-kappaB, and induction of apoptosis in human endothelial cells by glucose: Role of nitric oxide synthase? Free Radic Biol Med. 1999;27:752-763.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 752-763
-
-
Du, X.1
Stocklauser-Farber, K.2
Rosen, P.3
-
9
-
-
0033852205
-
Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells
-
Zhuang S, Simon G. Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells. Am J Physiol Cell Physiol. 2000;279:341-351.
-
(2000)
Am J Physiol Cell Physiol
, vol.279
, pp. 341-351
-
-
Zhuang, S.1
Simon, G.2
-
10
-
-
0026769228
-
Tubulointerstitial changes as a major determinant in the progression of renal damage
-
Nath KA. Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kidney Dis. 1992;20:1-17.
-
(1992)
Am J Kidney Dis
, vol.20
, pp. 1-17
-
-
Nath, K.A.1
-
11
-
-
84880928618
-
Pathophysiological mechanisms involving aggressive islet cell destruction in fulminant type 1 diabetes
-
Tanaka S, Aida K, Nishida Y, Kobayashi T. Pathophysiological mechanisms involving aggressive islet cell destruction in fulminant type 1 diabetes. Endocr J. 2013;60:837-845.
-
(2013)
Endocr J
, vol.60
, pp. 837-845
-
-
Tanaka, S.1
Aida, K.2
Nishida, Y.3
Kobayashi, T.4
-
12
-
-
35548998407
-
Effects of grape seed proanthocyanidins extracts on experimental diabetic nephropathy in rats
-
Liu YN, Shen XN, Yao GY. Effects of grape seed proanthocyanidins extracts on experimental diabetic nephropathy in rats. Wei Sheng Yan Jiu. 2006;35:703-705.
-
(2006)
Wei Sheng Yan Jiu
, vol.35
, pp. 703-705
-
-
Liu, Y.N.1
Shen, X.N.2
Yao, G.Y.3
-
14
-
-
34248664111
-
Effects of advanced glycation end products on renal fibrosis and oxidative stress in cultured NRK-49F cells
-
Yan HD, Li XZ, Xie JM, Li M. Effects of advanced glycation end products on renal fibrosis and oxidative stress in cultured NRK-49F cells. Chin Med J (Engl). 2007;120:787-793.
-
(2007)
Chin Med J (Engl)
, vol.120
, pp. 787-793
-
-
Yan, H.D.1
Li, X.Z.2
Xie, J.M.3
Li, M.4
-
15
-
-
29144527533
-
A new automated colorimetric method for measuring total oxidant status
-
Erel O. A new automated colorimetric method for measuring total oxidant status. Clin Biochem. 2005;38:1103-1111.
-
(2005)
Clin Biochem
, vol.38
, pp. 1103-1111
-
-
Erel, O.1
-
16
-
-
1542316295
-
A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation
-
Erel O. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem. 2004;37:277-285.
-
(2004)
Clin Biochem
, vol.37
, pp. 277-285
-
-
Erel, O.1
-
17
-
-
77449150316
-
Depressive status does not alter renal oxidative and immunological parameters during early diabetic nephropathy in rats
-
Rincon J, Pedreanez A, Viera N, Arcaya JL, Carrizo E, Mosquera J. Depressive status does not alter renal oxidative and immunological parameters during early diabetic nephropathy in rats. World J Biol Psychiatry. 2009;10:560-566.
-
(2009)
World J Biol Psychiatry
, vol.10
, pp. 560-566
-
-
Rincon, J.1
Pedreanez, A.2
Viera, N.3
Arcaya, J.L.4
Carrizo, E.5
Mosquera, J.6
-
18
-
-
20044390236
-
Diltiazem attenuates oxidative stress in diabetic rats
-
Anjaneyulu M, Chopra K. Diltiazem attenuates oxidative stress in diabetic rats. Ren Fail. 2005;27:335-344.
-
(2005)
Ren Fail
, vol.27
, pp. 335-344
-
-
Anjaneyulu, M.1
Chopra, K.2
-
19
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa T, Edelstein D, Du XL, et al. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature. 2000;404:787-790.
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
-
20
-
-
84859839717
-
Anti-apoptotic and antioxidant effects of grape seed proanthocyanidin extract in preventing cyclosporine A-induced nephropathy
-
Ulusoy S, Ozkan G, Yucesan FB, et al. Anti-apoptotic and antioxidant effects of grape seed proanthocyanidin extract in preventing cyclosporine A-induced nephropathy. Nephrology (Carlton). 2012;17:372-379.
-
(2012)
Nephrology (Carlton)
, vol.17
, pp. 372-379
-
-
Ulusoy, S.1
Ozkan, G.2
Yucesan, F.B.3
-
21
-
-
84894540141
-
Changes of total antioxidant capacity and total oxidant status of aqueous humor in diabetes patients and correlations with diabetic retinopath
-
Emrullah B, Ali BÇ, Esra E, et al. Changes of total antioxidant capacity and total oxidant status of aqueous humor in diabetes patients and correlations with diabetic retinopath. Int J Ophthalmol. 2013;6:531-536.
-
(2013)
Int J Ophthalmol
, vol.6
, pp. 531-536
-
-
Emrullah, B.1
Ali, B.Ç.2
Esra, E.3
-
22
-
-
0141618437
-
Attenuation of cyclosporineinduced renal dysfunction by catechin: Possible antioxidant mechanism
-
Anjaneyulu M, Tirkey N, Chopra K. Attenuation of cyclosporineinduced renal dysfunction by catechin: Possible antioxidant mechanism. Ren Fail. 2003;25:691-707.
-
(2003)
Ren Fail
, vol.25
, pp. 691-707
-
-
Anjaneyulu, M.1
Tirkey, N.2
Chopra, K.3
-
23
-
-
43449114799
-
Back-regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathy
-
Li BY, Cheng M, Gao HQ, et al. Back-regulation of six oxidative stress proteins with grape seed proanthocyanidin extracts in rat diabetic nephropathy. J Cell Biochem. 2008;104:668-679.
-
(2008)
J Cell Biochem
, vol.104
, pp. 668-679
-
-
Li, B.Y.1
Cheng, M.2
Gao, H.Q.3
-
24
-
-
9244249143
-
Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines
-
Pinent M, Blay M, Blade MC, Salvado MJ, Arola L, Ardevol A. Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines. Endocrinology. 2004;145:4985-4990.
-
(2004)
Endocrinology
, vol.145
, pp. 4985-4990
-
-
Pinent, M.1
Blay, M.2
Blade, M.C.3
Salvado, M.J.4
Arola, L.5
Ardevol, A.6
-
25
-
-
0034617986
-
Free radicals and grape seed proanthocyanidin extract: Importance in human health and disease prevention
-
Bagchi D, Bagchi M, Stohs SJ, et al. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology. 2000;148:187-197.
-
(2000)
Toxicology
, vol.148
, pp. 187-197
-
-
Bagchi, D.1
Bagchi, M.2
Stohs, S.J.3
-
26
-
-
70350337363
-
Preservation of cellular glutathione status and mitochondrial membrane potential by Nacetylcysteine and insulin sensitizers prevent carbonyl stressinduced human brain endothelial cell apoptosis
-
Okouchi M, Okayama N, Aw TY. Preservation of cellular glutathione status and mitochondrial membrane potential by Nacetylcysteine and insulin sensitizers prevent carbonyl stressinduced human brain endothelial cell apoptosis. Curr Neurovasc Res. 2009;6:267-278.
-
(2009)
Curr Neurovasc Res
, vol.6
, pp. 267-278
-
-
Okouchi, M.1
Okayama, N.2
Aw, T.Y.3
-
27
-
-
1842507259
-
Tubular and interstitial cell apoptosis in the streptozotocin-diabetic rat kidney
-
Kumar D, Zimpelmann J, Robertson S, Burns KD. Tubular and interstitial cell apoptosis in the streptozotocin-diabetic rat kidney. Nephron Exp Nephrol. 2004;96:77-88.
-
(2004)
Nephron Exp Nephrol
, vol.96
, pp. 77-88
-
-
Kumar, D.1
Zimpelmann, J.2
Robertson, S.3
Burns, K.D.4
-
28
-
-
0035930834
-
Role of caspases in human renal proximal tubular epithelial cell apoptosis
-
Wong VY, Keller PM, Nuttall ME, et al. Role of caspases in human renal proximal tubular epithelial cell apoptosis. Eur J Pharm. 2001;433:135-140.
-
(2001)
Eur J Pharm
, vol.433
, pp. 135-140
-
-
Wong, V.Y.1
Keller, P.M.2
Nuttall, M.E.3
-
29
-
-
0009530192
-
Human ICE/CED-3 protease nomenclature(Letter)
-
Alnemri E, Livingston DJ, Nicholson DW, et al. Human ICE/CED-3 protease nomenclature (Letter). Cell. 1996;87:171.
-
(1996)
Cell
, vol.87
, pp. 171
-
-
Alnemri, E.1
Livingston, D.J.2
Nicholson, D.W.3
-
30
-
-
0031044652
-
Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases
-
Alnemri ES. Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases. J Cell Biochem. 1997;64:33-42.
-
(1997)
J Cell Biochem
, vol.64
, pp. 33-42
-
-
Alnemri, E.S.1
-
31
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen GM. Caspases: The executioners of apoptosis. Biochem J. 1997;326:1-16.
-
(1997)
Biochem J
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
32
-
-
0036224782
-
Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients
-
Susanne M, Xia X, Jie T, Timothy SK. Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients. Diabetes. 2002;51:1172-1179.
-
(2002)
Diabetes
, vol.51
, pp. 1172-1179
-
-
Susanne, M.1
Xia, X.2
Jie, T.3
Timothy, S.K.4
-
33
-
-
79551584144
-
Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1b transcription in human adipose tissue
-
Koenen TB, Stienstra R, van Tits LJ, et al. Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1b transcription in human adipose tissue. Diabetes. 2011;60:517-524.
-
(2011)
Diabetes
, vol.60
, pp. 517-524
-
-
Koenen, T.B.1
Stienstra, R.2
Van Tits, L.J.3
-
34
-
-
0036762153
-
Thrombin activity and platelet microparticle formation are increased in type 2 diabetic platelets: A potential correlation with caspase activation
-
Cohen Z, Gonzales RF, Davis-Gorman GF, Copeland JG, McDonagh PF. Thrombin activity and platelet microparticle formation are increased in type 2 diabetic platelets: A potential correlation with caspase activation. Thromb Res. 2002;107:217-221.
-
(2002)
Thromb Res
, vol.107
, pp. 217-221
-
-
Cohen, Z.1
Gonzales, R.F.2
Davis-Gorman, G.F.3
Copeland, J.G.4
McDonagh, P.F.5
-
35
-
-
84899958819
-
GSPE is superior to NAC in the prevention of contrast-induced nephropathy: Might this superiority be related to caspase 1 and calpain 1?
-
Ulusoy S, Ozkan G, Mungan S, et al. GSPE is superior to NAC in the prevention of contrast-induced nephropathy: Might this superiority be related to caspase 1 and calpain 1? Life Sci. 2014;103:101-110.
-
(2014)
Life Sci
, vol.103
, pp. 101-110
-
-
Ulusoy, S.1
Ozkan, G.2
Mungan, S.3
-
36
-
-
0030827971
-
BH3 domain of BAD is required for heterodimerization with BCLXL and pro-apoptotic activity
-
Zha J, Harada H, Osipov K, Jockel J, Waksman G, Korsmeyer SJ. BH3 domain of BAD is required for heterodimerization with BCLXL and pro-apoptotic activity. J Biol Chem. 1997;272:24101-24104.
-
(1997)
J Biol Chem
, vol.272
, pp. 24101-24104
-
-
Zha, J.1
Harada, H.2
Osipov, K.3
Jockel, J.4
Waksman, G.5
Korsmeyer, S.J.6
-
37
-
-
0032080022
-
CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor
-
Inohara N, Koseki T, Chen S, Wu X, Nunez G. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. EMBO J. 1998;17:2526-2533.
-
(1998)
EMBO J
, vol.17
, pp. 2526-2533
-
-
Inohara, N.1
Koseki, T.2
Chen, S.3
Wu, X.4
Nunez, G.5
-
38
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C, Fang M, Li Y, Li L, Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell. 2000;102:33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
39
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen A, Ekert PG, Silke J, et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell. 2000;102:43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.1
Ekert, P.G.2
Silke, J.3
-
40
-
-
84875245083
-
Increased vulnerability to beta cell destruction and diabetes in mice lacking NAD(P)H: Quinone oxidoreductase 1
-
Yeo SH, Noh JR, Kim YH, et al. Increased vulnerability to beta cell destruction and diabetes in mice lacking NAD(P)H: Quinone oxidoreductase 1. Toxicol Lett. 2013;219:35-41.
-
(2013)
Toxicol Lett
, vol.219
, pp. 35-41
-
-
Yeo, S.H.1
Noh, J.R.2
Kim, Y.H.3
-
41
-
-
0032536519
-
Caspases are activated in a branched protease cascade and control distinct downstream processin Fas-induced apoptosis
-
Hirata H, Takahashi A, Kobayashi S, et al. Caspases are activated in a branched protease cascade and control distinct downstream processin Fas-induced apoptosis. J Exp Med. 1998;187:587-600.
-
(1998)
J Exp Med
, vol.187
, pp. 587-600
-
-
Hirata, H.1
Takahashi, A.2
Kobayashi, S.3
-
42
-
-
0033598145
-
Involvement of FADD and Caspase 8 signalling in detachment-induced apoptosis
-
Rytomaa M, Martin LM, Downward J. Involvement of FADD and Caspase 8 signalling in detachment-induced apoptosis. Curr Biol. 1999;9:587-600.
-
(1999)
Curr Biol
, vol.9
, pp. 587-600
-
-
Rytomaa, M.1
Martin, L.M.2
Downward, J.3
-
43
-
-
0030826338
-
FLICE is predominantly expressed as two functionally active isoforms, caspas 8/a and caspase 8/b
-
Scaffidi C, Medamma JP, Krammer PH, Peter ME. FLICE is predominantly expressed as two functionally active isoforms, caspas 8/a and caspase 8/b. J Biol Chem. 1997;272:1043-1046.
-
(1997)
J Biol Chem
, vol.272
, pp. 1043-1046
-
-
Scaffidi, C.1
Medamma, J.P.2
Krammer, P.H.3
Peter, M.E.4
-
44
-
-
14044252160
-
Caspase 8 can be activated by interchain proteolysis without receptor-triggered dimerization during-induced apoptosis
-
Sohn D, Schulze-Osthoff K, Janicke RU. Caspase 8 can be activated by interchain proteolysis without receptor-triggered dimerization during-induced apoptosis. J Biol Chem. 2005;280:5267-5273.
-
(2005)
J Biol Chem
, vol.280
, pp. 5267-5273
-
-
Sohn, D.1
Schulze-Osthoff, K.2
Janicke, R.U.3
|