Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils

Nature Communications

Volumn 6, Issue , 2015, Pages

  Zimmermann, Maili ^a   Aguilera, Francisco Bianchetto ^a   Castellucci, Monica ^a   Rossato, Marzia ^a   Costa, Sara ^a   Lunardi, Claudio ^b   Ostuni, Renato ^c   Girolomoni, Giampiero ^b   Natoli, Gioacchino ^c   Bazzoni, Flavia ^a   Tamassia, Nicola ^a   Cassatella, Marco A ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA; HISTONE; I KAPPA B; IL6 PROTEIN, HUMAN; IMIDAZOLE DERIVATIVE; INTERLEUKIN 12 RECEPTOR BETA1; LIGAND; MESSENGER RNA; NFKBIZ PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN BINDING; RESIQUIMOD; TNF PROTEIN, HUMAN; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR;

BLOOD; CYTOLOGY; GENE EXPRESSION; GENOME; NUCLEIC ACID; PROTEIN; SECRETION; SIGNALING;

ANIMAL CELL; ARTICLE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN REMODELLING; CONTROLLED STUDY; GENE EXPRESSION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; LEUKOCYTE ACTIVATION; MONOCYTE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; ANIMAL; AUTOCRINE EFFECT; BIOLOGICAL MODEL; BIOSYNTHESIS; C57BL MOUSE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DRUG EFFECTS; ENHANCER REGION; GENE LOCUS; GENETICS; INFLAMMATION; METABOLISM; NEUTROPHIL; PATHOLOGY; PERITONEUM; PROMOTER REGION;

ANIMALS; AUTOCRINE COMMUNICATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; ENHANCER ELEMENTS, GENETIC; GENETIC LOCI; GRANULOCYTE COLONY-STIMULATING FACTOR; HISTONES; HUMANS; I-KAPPA B PROTEINS; IMIDAZOLES; INFLAMMATION; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-12 RECEPTOR BETA 1 SUBUNIT; INTERLEUKIN-6; LIGANDS; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NEUTROPHIL ACTIVATION; NEUTROPHILS; NUCLEAR PROTEINS; PERITONEUM; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84923108417     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7061     Document Type: Article

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