Oxidative stress augments toll-like receptor 8 mediated neutrophilic responses in healthy subjects

Respiratory Research

Volumn 10, Issue , 2009, Pages

  Yanagisawa, Satoru ^a   Koarai, Akira ^a   Sugiura, Hisatoshi ^a   Ichikawa, Tomohiro ^a   Kanda, Masae ^a   Tanaka, Rie ^a   Akamatsu, Keiichiro ^a   Hirano, Tsunahiko ^a   Matsunaga, Kazuto ^a   Minakata, Yoshiaki ^a   Ichinose, Masakazu ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DEXAMETHASONE; HYDROGEN PEROXIDE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MYELOID DIFFERENTIATION FACTOR 88; RESIQUIMOD; SUPEROXIDE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; CYTOKINE; IMIDAZOLE DERIVATIVE; PANCREATIC ELASTASE; TRANSCRIPTION FACTOR RELA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; NEUTROPHIL; NORMAL HUMAN; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; BLOOD; DRUG EFFECT; DRUG POTENTIATION; FLOW CYTOMETRY; INFLAMMATION; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REFERENCE VALUE; SECRETION; VIROLOGY; VIRUS INFECTION;

ACETYLCYSTEINE; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; FLOW CYTOMETRY; HUMANS; HYDROGEN PEROXIDE; IMIDAZOLES; INFLAMMATION; INTERLEUKIN-8; NEUTROPHILS; OXIDATIVE STRESS; PANCREATIC ELASTASE; PHOSPHORYLATION; REFERENCE VALUES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TRANSCRIPTION FACTOR RELA; VIRUS DISEASES;

EID: 70249090779     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-10-50     Document Type: Article

References (35)

1. MacNee W. Pulmonary and systemic oxidant/antioxidant imbalance in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2005, 2(1):50-60. 10.1513/pats.200411-056SF, 16113469.
2. Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J 2006, 28(1):219-242. 10.1183/09031936.06.00053805, 16816350.
3. Barnes PJ, Chung KF, Page CP. Inflammatory mediators of asthma: an update. Pharmacol Rev 1998, 50(4):515-596.
4. Sugiura H, Ichinose M. Oxidative and nitrative stress in bronchial asthma. Antioxid Redox Signal 2008, 10(4):785-797. 10.1089/ars.2007.1937, 18177234.
5. Brown RK, Kelly FJ. Evidence for increased oxidative damage in patients with cystic fibrosis. Pediatr Res 1994, 36(4):487-493. 10.1203/00006450-199410000-00013, 7816524.
6. Starosta V, Rietschel E, Paul K, Baumann U, Griese M. Oxidative changes of bronchoalveolar proteins in cystic fibrosis. Chest 2006, 129(2):431-437. 10.1378/chest.129.2.431, 16478863.
7. Cantin AM, North SL, Fells GA, Hubbard RC, Crystal RG. Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis. J Clin Invest 1987, 79(6):1665-1673. 424497, 3034979, 10.1172/JCI113005.
8. Kinnula VL, Fattman CL, Tan RJ, Oury TD. Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy. Am J Respir Crit Care Med 2005, 172(4):417-422. 10.1164/rccm.200501-017PP, 15894605.
9. DeForge LE, Fantone JC, Kenney JS, Remick DG. Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood. J Clin Invest 1992, 90(5):2123-2129. 443281, 1331181, 10.1172/JCI116097.
10. Tanaka C, Kamata H, Takeshita H, Yagisawa H, Hirata H. Redox regulation of lipopolysaccharide (LPS)-induced interleukin-8 (IL-8) gene expression mediated by NF kappa B and AP-1 in human astrocytoma U373 cells. Biochem Biophys Res Commun 1997, 232(2):568-573. 10.1006/bbrc.1997.6264, 9125224.
11. Fahy JV, Kim KW, Liu J, Boushey HA. Prominent neutrophilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol 1995, 95(4):843-852. 10.1016/S0091-6749(95)70128-1, 7722165.
12. Wark PA, Johnston SL, Moric I, Simpson JL, Hensley MJ, Gibson PG. Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma. Eur Respir J 2002, 19(1):68-75. 10.1183/09031936.02.00226302, 11852895.
13. Drost EM, Skwarski KM, Sauleda J, Soler N, Roca J, Agusti A, MacNee W. Oxidative stress and airway inflammation in severe exacerbations of COPD. Thorax 2005, 60(4):293-300. 1747355, 15790984, 10.1136/thx.2004.027946.
14. Papi A, Bellettato CM, Braccioni F, Romagnoli M, Casolari P, Caramori G, Fabbri LM, Johnston SL. Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations. Am J Respir Crit Care Med 2006, 173(10):1114-1121. 10.1164/rccm.200506-859OC, 16484677.
15. Underhill DM, Ozinsky A. Toll-like receptors: key mediators of microbe detection. Curr Opin Immunol 2002, 14(1):103-110. 10.1016/S0952-7915(01)00304-1, 11790539.
16. Hayashi F, Means TK, Luster AD. Toll-like receptors stimulate human neutrophil function. Blood 2003, 102(7):2660-2669. 10.1182/blood-2003-04-1078, 12829592.
17. Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004, 303(5663):1526-1529. 10.1126/science.1093620, 14976262.
18. Diebold SS, Kaisho T, Hemmi H, Akira S, Reise Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004, 303(5663):1529-1531. 10.1126/science.1093616, 14976261.
19. Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, Iwasaki A, Flavell RA. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci USA 2004, 101(15):5598-5603. 397437, 15034168, 10.1073/pnas.0400937101.
20. Takeda K, Akira S. Toll-like receptors in innate immunity. Int Immunol 2005, 17(1):1-14. 10.1093/intimm/dxh186, 15585605.
21. Wang JP, Bowen GN, Padden C, Cerny A, Finberg RW, Newburger PE, Kurt-Jones EA. Toll-like receptor-mediated activation of neutrophils by influenza A virus. Blood 2008, 112(5):2028-2034. 10.1182/blood-2008-01-132860, 18544685.
22. Hattermann K, Picard S, Borgeat M, Leclerc P, Pouliot M, Borgeat P. The Toll-like receptor 7/8-ligand resiquimod (R-848) primes human neutrophils for leukotriene B4, prostaglandin E2 and platelet-activating factor biosynthesis. FASEB J 2007, 21(7):1575-1585. 10.1096/fj.06-7457com, 17264163.
23. Yamagata T, Sugiura H, Yokoyama T, Yanagisawa S, Ichikawa T, Ueshima K, Akamatsu K, Hirano T, Nakanishi M, Yamagata Y, Matsunaga K, Minakata Y, Ichinose M. Overexpression of CD-11b and CXCR1 on circulating neutrophils: its possible role in COPD. Chest 2007, 132(3):890-899. 10.1378/chest.07-0569, 17573488.
24. Ito K, Hanazawa T, Tomita K, Barnes PJ, Adcock IM. Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem Biophys Res Commun 2004, 315(1):240-245. 10.1016/j.bbrc.2004.01.046, 15013452.
25. Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, Horiuchi T, Tomizawa H, Takeda K, Akira S. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002, 3(2):196-200. 10.1038/ni758, 11812998.
26. Jurk M, Heil F, Vollmer J, Schetter C, Krieg AM, Wagner H, Lipford G, Bauer S. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 2002, 3(6):499. 10.1038/ni0602-499, 12032557.
27. DeForge LE, Preston AM, Takeuchi E, Kenney J, Boxer LA, Remick DG. Regulation of interleukin 8 gene expression by oxidant stress. J Biol Chem 1993, 268(34):25568-25576.
28. Schreck R, Rieber P, Baeuerle PA. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. Embo J 1991, 10(8):2247-2258. 452914, 2065663.
29. Janssen-Heininger YM, Macara I, Mossman BT. Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants. Am J Respir Cell Mol Biol 1999, 20(5):942-952.
30. de Oliveira-Marques V, Cyrne L, Marinho HS, Antunes F. A quantitative study of NF-kappaB activation by H2O2: relevance in inflammation and synergy with TNF-alpha. J Immunol 2007, 178(6):3893-3902.
31. Kamata H, Manabe T, Oka S, Kamata K, Hirata H. Hydrogen peroxide activates IkappaB kinases through phosphorylation of serine residues in the activation loops. FEBS Lett 2002, 519(1-3):231-237. 10.1016/S0014-5793(02)02712-6, 12023051.
32. Takada Y, Mukhopadhyay A, Kundu GC, Mahabeleshwar GH, Singh S, Aggarwal BB. Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. J Biol Chem 2003, 278(26):24233-24241. 10.1074/jbc.M212389200, 12711606.
33. Ito K, Lim S, Caramori G, Chung KF, Barnes PJ, Adcock IM. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. FASEB J 2001, 15(6):1110-1112.
34. Powers KA, Szaszi K, Khadaroo RG, Tawadros PS, Marshall JC, Kapus A, Rotstein OD. Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages. J Exp Med 2006, 203(8):1951-1961. 2118368, 16847070, 10.1084/jem.20060943.
35. Yanagisawa S, Sugiura H, Yokoyama T, Yamagata T, Ichikawa T, Akamatsu K, Koarai A, Hirano T, Nakanishi M, Matsunaga K, Minakata Y, Ichinose M. The possible role of hematopoietic cell kinase in the pathophysiology of COPD. Chest 2009, 135(1):94-101. 10.1378/chest.07-3020, 18719065.