Design and evaluation of pH-sensitive liposomes constructed by poly(2-ethyl-2-oxazoline)-cholesterol hemisuccinate for doxorubicin delivery

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 91, Issue , 2015, Pages 66-74

  Xu, Huan ^a   Hu, Meina ^a   Yu, Xiu ^a   Li, Yan ^a   Fu, Yuanshan ^b   Zhou, Xiaoxia ^a   Zhang, Di ^a   Li, Jianying ^a  

^a LIAONING NORMAL UNIVERSITY   (China)

^b Zhongshan Hospital   (China)

Author keywords

Cholesterol hemisuccinate; Liposomes; PEG dilemma; PEGylation; pH sensitive; Poly(2 ethyl 2 oxazoline)

Indexed keywords

CHOLESTEROL HYDROGEN SUCCINATE; DOXORUBICIN; HEMOGLOBIN; LIPOSOME; MACROGOL; POLY(2 ETHYL 2 OXAZOLINE)CHOLESTEROL HEMISUCCINATE; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; CHOLESTEROL; CHOLESTEROL ESTER; POLY(2-ETHYL-2-OXAZOLINE); POLY(2-ETHYL-2-OXAZOLINE)-CHOLESTEROL HEMISUCCINATE; POLYAMINE;

A375 CELL LINE; ARTICLE; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; ENDOSOME; ERYTHROCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIPOSOMAL DELIVERY; NANOENCAPSULATION; NANOPHARMACEUTICS; PARTICLE SIZE; PH; SENSITIVITY ANALYSIS; SURFACE PROPERTY; SYNTHESIS; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; CELL NUCLEUS; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; DRUG DELIVERY SYSTEM; DRUG EFFECTS; ENDOCYTOSIS; MELANOMA; MEMBRANE FUSION; METABOLISM; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; CHOLESTEROL; CHOLESTEROL ESTERS; DOXORUBICIN; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; ENDOCYTOSIS; ENDOSOMES; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOSOMES; MELANOMA; MEMBRANE FUSION; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE; PARTICLE SIZE; POLYAMINES;

EID: 84923095580     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.01.030     Document Type: Article

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