The design and synthesis of polymers for eukaryotic membrane disruption

Journal of Controlled Release

Volumn 61, Issue 1-2, 1999, Pages 137-143

  Murthy, Niren ^a   Robichaud, John R ^a   Tirrell, David A ^b   Stayton, Patrick S ^a   Hoffman, Allan S ^a  

^a University of Washington   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Drug delivery; Endosomal release; Gene therapy; Hemolysis; pH sensitive polymers

Indexed keywords

POLYMER;

ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; ENDOSOME; EUKARYOTIC CELL; GENE THERAPY; HEMOLYSIS; LIPID BILAYER; MEMBRANE DAMAGE; NONHUMAN; PH; PRIORITY JOURNAL;

CELL MEMBRANE; DRUG DELIVERY SYSTEMS; HEMOLYSIS; HUMANS; HYDROGEN-ION CONCENTRATION; MELITTEN; POLYMERS;

EID: 0032818167     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00114-5     Document Type: Article

References (14)

1. Mitchell P. Vector problems still thwart gene-therapy promise. Lancet. 351:1998;346.
2. Plank C., Oberhauser B., Mechtler K., Koch C., Wagner E. The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. J. Biol. Chem. 269:1994;12918-12924.
3. Haensler J., Szoka F. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjugate Chem. 4:1993;372-379.
4. 2 terminus of vesicular stomatitis virus glycoprotein is a pH-dependent hemolysin. J. Biol. Chem. 259:1984;4691-4694.
5. Jayasuriya N., Bosak S., Regen S.L. Supramolecular surfactants: Polymerized boalphiles exhibiting extraordinarily high membrane-disrupting activity. J. Am. Chem. Soc. 112:1990;5844-5850.
6. Thomas J., Tirrell D.A. Polyelectrolyte-sensitized phospholipid vesicles. Acc. Chem. Res. 25:1992;336-342.
7. Ferrito M., Tirrell D.A. Poly(2-ethylacrylic acid). Macromol. Synth. 11:1992;59-62.
8. Chung J.C., Gross D.J., Thomas J.L., Tirrell D.A., Opsahl-Ong L.R. pH sensitive, cation selective channels formed by a simple synthetic polyelectrolyte in artificial bilayer membranes. Macromolecules. 29:1996;4636-4641.
9. Tosteson M.T., Holmes S.J., Razin M., Tosteson D.C. Melittin lysis of red blood cells. J. Membrane Biol. 87:1985;35-44.
10. Hughes J.A., Aronsohn A.I., Avrutskaya A.V., Juliano R.L. Evaluation of adjuvants that enhance the effectiveness of antisense oligodeoxynucleotides. Pharm. Res. 13:1996;404-410.
11. Joyce D.E., Kurucsev T. Hydrogen ion equilibria in poly(methacrylic acid) and poly(ethacrylic acid) solutions. Polymer. 22:1981;415-417.
12. Meyer O., Papahadjopoulos D., Leroux J.C. Copolymers of N-isopropylacrylamide can trigger pH sensitivity to stable liposomes. FEBS. 421:1998;61-64.
13. Greenely R.Z. Free Radical Copolymerization Reactivity Ratios. Brandrup J., Immergut E.H. Polymer Handbook. 1989;153-267 Wiley, New York.
14. Rosen S.L. Fundamental Principles of Polymeric Materials. 1993;Wiley, New York.