Suppression in mice of immunosurveillance against PEGylated liposomes by encapsulated doxorubicin

Journal of Controlled Release

Volumn 192, Issue , 2014, Pages 167-173

  Yahuafai, Jantana ^a,b   Asai, Tomohiro ^a   Nakamura, Genki ^a   Fukuta, Tatsuya ^a   Siripong, Pongpun ^b   Hyodo, Kenji ^c   Ishihara, Hiroshi ^c   Kikuchi, Hiroshi ^c   Oku, Naoto ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b NATIONAL CANCER INSTITUTE   (Thailand)

^c EISAI CO LTD   (Japan)

Author keywords

Biodistribution; Doxorubicin; Immunosurveillance; PEGylated liposomes; Repetitive administration

Indexed keywords

BLOOD; LIPOSOMES; LIVER; MACROPHAGES; PHARMACOKINETICS;

BIODISTRIBUTIONS; DOXORUBICIN; FLOW-CYTOMETRIC ANALYSIS; IMMUNOSURVEILLANCE; KUPFFER CELLS; PEGYLATED LIPOSOMES; PLASMA CONCENTRATION; SEVERE COMBINED IMMUNODEFICIENCIES;

MAMMALS;

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DOXORUBICIN; LIPOSOME; ANTINEOPLASTIC ANTIBIOTIC; MACROGOL DERIVATIVE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CELL DAMAGE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG HALF LIFE; ENCAPSULATION; FLOW CYTOMETRY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOSURVEILLANCE; KUPFFER CELL; LIVER; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; SCID MOUSE; SPLEEN; SPLEEN WEIGHT; WEIGHT REDUCTION; CELL COUNT; IMMUNOMODULATION; NANOENCAPSULATION; ANIMAL; BAGG ALBINO MOUSE; DRUG EFFECTS; IMMUNOLOGICAL MONITORING; IMMUNOLOGY; METABOLISM;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DOXORUBICIN; KUPFFER CELLS; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; MICE, SCID; MONITORING, IMMUNOLOGIC; POLYETHYLENE GLYCOLS;

EID: 84905175062     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.07.010     Document Type: Article

References (20)

1. N. Oku, and Y. Namba Long-circulating liposomes Crit. Rev. Ther. Drug Carrier Syst. 11 1994 231 270
2. F.H. Roerdink, J. Dijkstra, H.H. Spanjer, and G.L. Scherphof Interaction of liposomes with hepatocytes and Kupffer cells in vivo and in vitro Biochem. Soc. Trans. 12 1984 335 336 (Pubitemid 14138497)
3. T. Daemen, G. Hofstede, M.T. Ten Kate, I.A. Bakker-Woudenberg, and S. GL. Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages Int. J. Cancer 61 1995 716 721
4. A.L. Klibanov, K. Maruyama, V.P. Torchilin, and L. Huang Amphipathic polyethyleneglycols effectively prolong the circulation time of liposomes FEBS Lett. 268 1990 235 237 (Pubitemid 20233874)
5. T.M. Allen t, C. Hansen, F. Martin, C. Redemann, and A. Yau-Young Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo Biochim. Biophys. Acta 1066 1991 29 36
6. Y. Matsumura, and H. Maeda A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs Cancer Res. 46 1986 6387 6392 (Pubitemid 17221789)
7. T. Safra, F. Muggia, S. Jeffers, D.D. Tsao-Wei, S. Groshen, R.O. Lyass, G. Henderson, Berry, and A. Gabizon Pegylated liposomal doxorubicin (doxil): reduced clinical cardiotoxicity in patients reaching or exceeding cumulative doses of 500 mg/m2 Ann. Oncol. 11 2000 1029 1033
8. Y. Barenholz Doxil(R) - the first FDA-approved nano-drug: lessons learned J. Control.Release 160 2012 117 134
9. Alberto Gabizon, Raphael Catane, Beatrice Uziely, Bela Kaufman, Tamar Safra, Rivka Cohen, Francis Martin, Anthony Huang, and Y. Barenholz Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes Cancer Res. 154 1994 987 992 (Pubitemid 24085451)
10. Toos Daemen, Joke Regts, Maarten Meesters, Marian T. Ten Kate, Irma A.J.M. Bakker-Woudenberg, and G.L. Scherphof Toxicity of doxorubicin entrapped within long-circulating liposomes J. Control. Release 44 1997 1 9 (Pubitemid 27051329)
11. Robert D. Arnold, Donald E. Mager, Jeanine E. Slack, and R.M. Straubinger Effect of repetitive administration of doxorubicin-containing liposomes on plasma pharmacokinetics and drug biodistribution in a rat brain tumor model Clin. Cancer Res. 2005 December 15 2005 8856 8865 (Pubitemid 43005938)
12. A. Gabizon, D. Tzemach, L. Mak, M. Bronstein, and H. AT. Dose dependency of pharmacokinetics and therapeutic efficacy of pegylated liposomal doxorubicin (DOXIL) in murine models J. Drug Target. 10 2002 539 548 (Pubitemid 36124352)
13. Yusuke Ohara, Tatsuya Oda, Keiichi Yamada, Shinji Hashimoto, Yoshimasa Akashi, Ryoichi Miyamoto, Akihiko Kobayashi, Kiyoshi Fukunaga, Ryoko Sasaki, and N. Ohkohchi Effective delivery of chemotherapeutic nanoparticles by depleting host Kupffer cells Int. J. Cancer 131 2012 2402 2410
14. H. Koide, T. Asai, K. Hatanaka, S. Akai, T. Ishii, E. Kenjo, T. Ishida, H. Kiwada, H. Tsukada, and N. Oku T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes Int. J. Pharm. 392 2010 218 223
15. T. Ishida, M. Ichihara, X. Wang, K. Yamamoto, J. Kimura, E. Majima, and H. Kiwada Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes J. Control. Release 112 2006 15 25
16. A.S. Abu Lila, H. Kiwada, and T. Ishida The accelerated blood clearance (ABC) phenomenon: clinical challenge and approaches to manage J. Control. Release 172 2013 38 47
17. T. Ishida, M. Harada, X.Y. Wang, M. Ichihara, K. Irimura, and H. Kiwada Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes J. Control. Release 105 2005 305 317 (Pubitemid 40941995)
18. T. Ishida, K. Atobe, X. Wang, and H. Kiwada Accelerated blood clearance of PEGylated liposomes upon repeated injections: effect of doxorubicin- encapsulation and high-dose first injection J. Control. Release 115 2006 251 258 (Pubitemid 44634849)
19. Fan Xuy, Peng Zheny, Yu Zheng, Feng LIjuan, Yang Aiting, Cong Min, You Hong, and J. Jidong Preparation of Kupffer cell enriched non-parenchymal liver cells with high yield and reduced damage of surface markers by a modified method for flow cytometry Cell Biol. Int. 37 2013 284 291
20. Wei Liu, Yufang Hou, Huahai Chen, Handong Wei, Weiran Lin, Jichang Li, Ming Zhang, Fuchu He, and Y. Jiang Sample preparation method for isolation of single-cell types from mouse liver for proteomic studies Proteomics 11 2011 3556 3564