Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis

Oncology Reports

Volumn 32, Issue 4, 2014, Pages 1622-1630

  Xiang, Wei ^a   Jiang, Ting ^a   Guo, Fengjing ^a   Gong, Chen ^a   Yang, Kaixiang ^a   Wu, Yingxing ^a   Huang, Xin ^a   Cheng, Weiting ^b   Xu, Kai ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN NO 1 HOSPITAL   (China)

Author keywords

Chondrosarcoma; Hedgehog pathway inhibitor 4; Invasion; Migration; Primary cilia; Proliferation

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PROTEIN; GELATINASE A; GELATINASE B; HEDGEHOG PATHWAY INHIBITOR 4; MITOGEN ACTIVATED PROTEIN KINASE; PARATHYROID HORMONE RELATED PROTEIN; PROTEIN IFT88; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG; CILIOBREVIN A; MESSENGER RNA; QUINAZOLINONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CELL INVASION; CHONDROSARCOMA; CHONDROSARCOMA CELL LINE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; ENZYME REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MIGRATION INHIBITION; ONCOLOGICAL PARAMETERS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SW1353 CELL LINE; TUMOR CILIOGENESIS; BONE TUMOR; CELL MOTION; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; EUKARYOTIC FLAGELLUM; GENETICS; TUMOR CELL LINE;

BONE NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHONDROSARCOMA; CILIA; HEDGEHOG PROTEINS; HUMANS; QUINAZOLINONES; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR STEM CELL ASSAY;

EID: 84923068230     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3372     Document Type: Article

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