Cannabinoid CB2 receptor (CB2R) stimulation delays rubrospinal mitochondrial-dependent degeneration and improves functional recovery after spinal cord hemisection by ERK1/2 inactivation

Cell Death and Disease

Volumn 5, Issue 9, 2014, Pages

  Latini, L ^a   Bisicchia, E ^a   Sasso, V ^a   Chiurchiu V ^a,b   Cavallucci, V ^a   Molinari, M ^a   Maccarrone, M ^a,c   Viscomi, M T ^a  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b UNIVERSITY OF TERAMO   (Italy)

^c UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 3 (1 NAPHTHOYL) 1 PROPYLINDOLE; APOPTOSOME; CANNABINOID 2 RECEPTOR; CASPASE 3; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; CANNABINOID 1 RECEPTOR; FLAVONOID; INDOLE DERIVATIVE; JHW 015;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DAMAGE; CELL DEATH; CELL FATE; CERVICAL SPINE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME RELEASE; MALE; MITOCHONDRION; NERVE CELL DEGENERATION; NERVE FIBER TRANSECTION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; RUBROSPINAL NEURON; SIGNAL TRANSDUCTION; SPINAL CORD ATROPHY; SPINAL CORD HEMISECTION; SPINAL CORD INJURY; SPINAL CORD NERVE CELL; SPINAL NERVE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CONVALESCENCE; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; PATHOLOGY; PHOSPHORYLATION; UPREGULATION; WISTAR RAT;

RATTUS;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CYTOCHROMES C; FLAVONOIDS; INDOLES; MALE; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEURONS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RECEPTOR, CANNABINOID, CB1; RECEPTOR, CANNABINOID, CB2; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION; SPINAL CORD INJURIES; UP-REGULATION;

EID: 84923053244     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.364     Document Type: Article

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