Targeting TIM-1 on CD4 T cells depresses macrophage activation and overcomes ischemia-reperfusion injury in mouse orthotopic liver transplantation

American Journal of Transplantation

Volumn 13, Issue 1, 2013, Pages 56-66

  Zhang, Y ^a,b   Ji, H ^a   Shen, X ^a   Cai, J ^a,c   Gao, F ^a   Koenig, K M ^a   Batikian, C M ^a   Busuttil, R W ^a   Kupiec Weglinski, J W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ZHEJIANG UNIVERSITY   (China)

^c TIANJIN FIRST CENTRAL HOSPITAL   (China)

Author keywords

Innate immunity; ischemia reperfusion injury; orthotopic liver transplantation; T cell costimulation; TIM 1

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 22; INTERLEUKIN 4; MUCIN; T CELL IMMUNOGLOBULIN MUCIN 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CRYOPRESERVATION; HOMEOSTASIS; INNATE IMMUNITY; LIVER INJURY; LIVER TRANSPLANTATION; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; TEMPERATURE;

ANIMALS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNITY, INNATE; LIVER TRANSPLANTATION; MACROPHAGE ACTIVATION; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 84871714144     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2012.04316.x     Document Type: Article

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