CXCR3+CD4+ T cells mediate innate immune function in the pathophysiology of liver ischemia/reperfusion injury

Journal of Immunology

Volumn 176, Issue 10, 2006, Pages 6313-6322

  Zhai, Yuan ^a   Shen, Xiu Da ^a   Hancock, Wayne W ^b   Gao, Feng ^a   Qiao, Bo ^a   Lassman, Charles ^a   Belperio, John A ^a   Strieter, Robert M ^a   Busuttil, Ronald W ^a   Kupiec Weglinski, Jerzy W ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UCLA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD4 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CXCR3; COMPLEMENTARY DNA; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GENE PRODUCT; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA MICROARRAY; IMMUNOHISTOLOGY; INFLAMMATION; INNATE IMMUNITY; LIVER ISCHEMIA; LIVER RESECTION; LIVER TRANSPLANTATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; T LYMPHOCYTE ACTIVATION;

EID: 33646466622     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.10.6313     Document Type: Article

References (34)

1. Laskowski, I., J. Pratschke, M. J. Wilhelm, M. Gasser, and N. L. Tilney. 2000. Molecular and cellular events associated with ischemia/reperfusion injury. Ann. Transplant. 5: 29-35.
2. Farmer, D., F. Amersi, J. W. Kupiec-Weglinski. and R. W. Busuttil. 2000. Current status of ischemia and reperfusion injury in the liver. Transplant. Rev. 14: 106-126.
3. Fellstrom, B., L. M. Akuyrek, U. Backman, E. Larsson, J. Melin, and L. Zezina. 1998. Postischemic reperfusion injury and allograft arteriosclerosis. Transplant. Proc. 30: 4278-4280.
4. Howard, T. K., G. B. Klintmalm, J. B. Cofer, B. S. Husberg, R. M. Goldstein, and T. A. Gonwa. 1990. The influence of preservation injury on rejection in the hepatic transplant recipient. Transplantation 49: 103-107.
5. Jaeschke, H. 2003. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am. J. Physiol. 284: G15-G26.
6. Fondevila, C., R. W. Busuttil, and J. W. Kupiec-Weglinski. 2003. Hepatic ischemia/reperfusion injury-a fresh look. Exp. Mol. Pathol. 74: 86-93.
7. Zhai, Y., X. D. Shen, R. O'Connell, F. Gao, C. Lassman, R. W. Busuttil, G. Cheng, and J. W. Kupiec-Weglinski. 2004. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J. Immunol. 173: 7115-7119.
8. Rabb, H. 2002. The T cell as a bridge between innate and adaptive immune systems: implications for the kidney. Kidney Int. 61: 1935-1946.
9. + T-lymphocytes mediate ischemia/reperfusion- induced inflammatory responses in mouse liver. J. Clin. Invest. 100: 279-289.
10. Rabb, H., F. Daniels, M. O'Donnell, M. Haq, S. R. Saba, W. Keane, and W. W. Tang. 2000. Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice. Am. J. Physiol. 279: F525-F531.
11. Yokota, N., F. Daniels, J. Crosson, and H. Rabb. 2002. Protective effect of T cell depletion in murine renal ischemia-reperfusion injury. Transplantation 74: 759-763.
12. Shen, X. D., B. Ke, Y. Zhai, F. Amersi, F. Gao, D. M. Anselmo, R. W. Busuttil, and J. W. Kupiec-Weglinski. 2002. CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on home oxygenase-1 mediated cytoprotection. Transplantation 74: 315-319.
13. Belperio, J. A., M. P. Keane, M. D. Burdick, J. P. Lynch, 3rd, Y. Y. Xuc, K. Li, D. J. Ross, and R. M. Strieter. 2002. Critical role for CXCR3 chemokine biology in the pathogenesis of bronchiolitis obliterans syndrome. J. Immunol. 169: 1037-1049.
14. Mullane, K. M., R. Kraemer, and B. Smith. 1985. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Methods 14: 157-167.
15. Amersi, F., R. Buelow, H. Kato, B. Ke, A. J. Coito, X. D. Shen, D. Zhao, J. Zaky, J. Melinek, C. R. Lassman. et al. 1999. Upregulation of home oxygenase-1 protects genetically fat Zucker rat livers from ischemia/reperfusion injury. J. Clin. Invest. 104: 1631-1639.
16. Anselmo, D. M., F. F. Amersi, X. D. Shen, F. Gao, M. Katori, C. Lassman, B. Ke, A. J. Coito, J. Ma, V. Brinkmann, et al. 2002. FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration. Am. J. Transplant. 2: 843-849.
17. Suzuki, S., and L. H. Toledo-Pereyra. 1994. Interleukin 1 and tumor necrosis factor production as the initial stimulants of liver ischemia and reperfusion injury. J. Surg. Res. 57: 253-258.
18. Shirasugi, N., G. Wakabayashi, M. Shimazu, A. Oshima, M. Shito, S. Kawachi, T. Karahashi, Y. Kumamoto, M. Yoshida, and M. Kitajima. 1997. Up-regulation of oxygen-derived free radicals by interleukin-1 in hepatic ischemia/reperfusion injury. Transplantation 64: 1398-1403.
19. Shito, M., G. Wakabayashi, M. Ueda, M. Shimazu, N. Shirasugi, M. Endo, M. Mukai, and M. Kitajima. 1997. Interleukin 1 receptor blockade reduces tumor necrosis factor production, tissue injury, and mortality after hepatic ischemia-reperfusion in the rat. Transplantation 63: 143-148.
20. Koo, D. D. H., and S. V. Fuggle. 2002, Chemokines in ischemia/reperfusion injury. Curr. Opin. Organ Transplant. 7: 100-106.
21. Sekido, N., N. Mukaida, A. Harada, I. Nakanishi, Y. Watanabe, and K. Matsushima. 1993. Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8. Nature 365: 654-657.
22. Boyle, E. M., Jr., J. C. Kovacich, C. A. Hebert, T. G. Canty, Jr., E. Chi, E. N. Morgan, T. H. Pohlman, and E. D. Verrier. 1998. Inhibition of interleukin-8 blocks myocardial ischemia-reperfusion injury. J. Thorac. Cardiovasc. Surg. 116: 114-121.
23. Chandrasekar, B., J, B. Smith, and G. L. Freeman. 2001. Ischemia-reperfusion of rat myocardium activates nuclear factor-κB and induces neutrophil infiltration via lipopolysaccharide-induced CXC chemokine. Circulation 103: 2296-2302.
24. Miura, M., X. Fu, Q. W. Zhang, D. G. Remick, and R. L. Fairchild. 2001. Neutralization of Gro α and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury. Am. J. Pathol. 159: 2137-2145.
25. Bertini, R., M. Allegretti, C. Bizzarri, A. Moriconi, M. Locati, G. Zampella, M. N. Cervellera, V. Di Cioccio, M. C. Cesta, E. Galliera, et al. 2004. Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury. Proc. Natl. Acad. Sci USA 101: 11791-11796.
26. Cugini, D., N. Azzoliini, E. Gagliardini, P. Cassis, R. Bertini, F. Colotta, M. Noris, G. Remuzzi, and A. Benigni. 2005. Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion. Kidney Int. 67: 1753-1761.
27. Tarzami, S. T., W. Miao, K. Mani, L. Lopez, S. M. Factor, J. W. Berman, and R. N. Kitsis. 2003. Opposing effects mediated by the chemokine receptor CXCR2 on myocardial ischemia-reperfusion injury: recruitment of potentially damaging neutrophils and direct myocardial protection. Circulation 108: 2387-2392.
28. Furuichi, K., T. Wada, Y. Iwata, K. Kitagawa, K. Kobayashi, H. Hashimoto, Y. Ishiwata, M. Asano, H. Wang, K. Matsushima, et al. 2003. CCR2 signaling contributes to ischemia-reperfusion injury in kidney. J. Am. Soc. Nephrol. 14: 2503-2515.
29. Homey, B., A. Muller, and A. Zlotnik. 2002. Chemokines: agents for the immunotherapy of cancer? Nat. Rev. Immunol. 2: 175-184.
30. Sallusto, F., A. Lanzavecchia, and C. R. Mackay. 1998. Chemokines and chemokine receptors in T-Cell priming and Th1/Th2-mediated responses. Immunol. Today 19: 568-574.
31. Shen, X. D., B. Ke, Y. Zhai, F. Gao, D. Anselmo, C. R. Lassman, R. W. Busuttil, and J. W. Kupiec-Weglinski. 2003. Stat4 and Stat6 signaling in hepatic ischemia/repertusion injury in mice: HO-I dependence of Stat4 disruption-mediated cytoprotection. Hepatology 37: 296-303.
32. Yokota, N., M. Burne-Taney, L. Racusen, and H. Rabb. 2003. Contrasting roles for STAT4 and STAT6 signal transduction pathways in murine renal ischemia-reperfusion injury. Am. J. Physiol. 285: F319-F325.
33. + T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol. Today 16: 34-38.
34. Takeda, K., T. Kaisho, and S. Akira. 2003. Toll-like receptors. Anna. Rev. Immunol. 21: 335-376.