DNA VACCINE;
HIGH MOBILITY GROUP B1 PROTEIN;
LYMPHOCYTE MEMBRANE RECEPTOR;
MONOCLONAL ANTIBODY;
PROTEIN T CELL IMMUNOGLOBULIN MUCIN DOMAIN 3;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
CANCER INFILTRATION;
CONTROLLED STUDY;
DENDRITIC CELL;
ENDOSOME;
IMMUNE RESPONSE;
IMMUNOSUPPRESSIVE TREATMENT;
MOUSE;
NONHUMAN;
PRIORITY JOURNAL;
PROTEIN EXPRESSION;
PROTEIN LOCALIZATION;
PROTEIN PROTEIN INTERACTION;
TUMOR REGRESSION;
Dendritic cells require a systemic type i interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
Longhi MP, Trumpfheller C, Idoyaga J et al. Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J. Exp. Med. 206, 589-1602 (2009).
Type i IFN as a natural adjuvant for a protective immune response: Lessons from the influenza vaccine model
Proietti E, Bracci L, Puzelli S et al. Type I IFN as a natural adjuvant for a protective immune response: lessons from the influenza vaccine model. J. Immunol. 169, 375-383 (2002).
Th1-specific cell surface protein TIM-3 regulates macrophage activation and severity of an autoimmune disease
Monney L, Sabatos CA, Gaglia JL et al. Th1-specific cell surface protein TIM-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415, 536-541 (2002).
TIM-3 pathway controls regulatory and effector T cell balance during hepatitis C virus infection
Moorman JP, Wang JM, Zhang Y et al. TIM-3 pathway controls regulatory and effector T cell balance during hepatitis C virus infection. J. Immunol. 189, 755-766 (2012).
TIM-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
Jones RB, Ndhlovu LC, Barbour JD et al. TIM-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J. Exp. Med. 205, 2763-2779 (2008).
Upregulation of TIM-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
Fourcade J, Sun Z, Benallaoua M et al. Upregulation of TIM-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J. Exp. Med. 207, 2175-2186 (2010).
Promotion of tissue inflammation by the immune receptor TIM-3 expressed on innate immune cells
Anderson AC, Anderson DE, Bregoli L et al. Promotion of tissue inflammation by the immune receptor TIM-3 expressed on innate immune cells. Science 318, 1141-1143 (2007).
Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
Chiba S, Baghdadi M, Akiba H et al. Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1. Nat. Immunol. 13, 832-842 (2012).
Galectin-9 increases TIM-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-TIM-3 interactions
Nagahara K, Arikawa T, Oomizu S et al. Galectin-9 increases TIM-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-TIM-3 interactions. J. Immunol. 181, 7660-7669 (2008).