Influence of socio-demographic features and apolipoprotein E epsilon 4 expression on the prevalence of dementia and cognitive impairment in a population of 70-74-year olds: The InveCe.Ab study

Archives of Gerontology and Geriatrics

Volumn 60, Issue 2, 2015, Pages 334-343

  Guaita, Antonio ^a   Vaccaro, Roberta ^a,b   Davin, Annalisa ^a   Colombo, Mauro ^a,b   Vitali, Silvia Francesca ^a,b   Polito, Letizia ^a   Abbondanza, Simona ^a   Valle, Eleonora ^a,b   Forloni, Gianluigi ^c   Ferretti, Virginia Valeria ^d   Villani, Simona ^d  

^a Golgi Cenci Foundation   (Italy)

^b CGolgi Geriatric Institute Piazza Golgi 11   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

Author keywords

Alzheimer's disease; ApoE e4; Cognitive impairment; Dementia; Prevalence; Risk factors

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E EPSILON 4; UNCLASSIFIED DRUG; APOLIPOPROTEIN E4;

AGED; ALZHEIMER DISEASE; ARTICLE; BIRTHPLACE; COGNITIVE DEFECT; COHORT ANALYSIS; DEMENTIA; DEMOGRAPHY; DIFFUSE LEWY BODY DISEASE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; ELDERLY CARE; FEMALE; FRONTOTEMPORAL DEMENTIA; HUMAN; ITALY; MALE; MILD COGNITIVE IMPAIRMENT; MULTIINFARCT DEMENTIA; POPULATION RESEARCH; PREVALENCE; PROTEIN EXPRESSION; RISK FACTOR; SEX DIFFERENCE; SINGLE (MARITAL STATUS); SOCIAL STATUS; AGE; COGNITION DISORDERS; EDUCATIONAL STATUS; GENETICS; HETEROZYGOTE; MARRIAGE; PROSPECTIVE STUDY;

AGE FACTORS; AGED; APOLIPOPROTEIN E4; COGNITION DISORDERS; DEMENTIA; EDUCATIONAL STATUS; FEMALE; HETEROZYGOTE; HUMANS; ITALY; MALE; MARITAL STATUS; PREVALENCE; PROSPECTIVE STUDIES; RISK FACTORS; SEX FACTORS;

EID: 84923018603     PISSN: 01674943     EISSN: 18726976     Source Type: Journal    
DOI: 10.1016/j.archger.2014.11.006     Document Type: Article

References (77)

1. Andel R., Crowe M., Hahn E.A., Mortimer J.A., Pedersen N.L., Fratiglioni L., et al. Work-related stress may increase the risk of vascular dementia. Journal of the American Geriatrics Society 2012, 60:60-67.
2. Andel R., Crowe M., Pedersen N.L., Mortimer J., Crimmins E., Johansson B., Gatz M. Complexity of work and risk of Alzheimer's disease: a population-based study of Swedish twins. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 2005, 60:P251-P258.
3. Andel R., Kåreholt I., Parker M.G., Thorslund M., Gatz M. Complexity of primary lifetime occupation and cognition in advanced old age. Journal of Aging and Health 2007, 19:397-415.
4. Andersen K., Launer L.J., Dewey M.E., Letenneur L., Ott A., Copeland J.R., et al. Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group. Neurology 1999, 53:1992-1997.
5. Andreoli V., Cassano G.B., Rossi R. DSM-IV-TR. Manuale diagnostico e statistico dei disturbi mentali 2007, Elsevier-Masson, Milan. 4th ed.
6. Andrieu S., Aboderin I., Baeyens J.P., Beard J., Benetos A., Berrut G., et al. IAGG workshop: Health promotion program on prevention of late onset dementia. The Journal of Nutrition, Health and Aging 2011, 15:562-575.
7. Atti A.R., Forlani C., De Ronchi D., Palmer K., Casadio P., Dalmonte E., Fratiglioni L. Cognitive impairment after age 60: clinical and social correlates in the Faenza Project. Journal of Alzheimer's Disease 2010, 21:1325-1334.
8. Azzimondi G., D'Alessandro R., Pandolfo G., Feruglio F.S. Comparative study of the prevalence of dementia in two Sicilian communities with different psychosocial backgrounds. Neuroepidemiology 1998, 17:199-209.
9. Baum L., Lam L.C.W., Kwok T., Lee J., Chiu H.F.K., Mok V.C.T., et al. Apolipoprotein E epsilon4 allele is associated with vascular dementia. Dementia and Geriatric Cognitive Disorders 2006, 22:301-305.
10. Ben-Shlomo Y., Kuh D. A life course approach to chronic disease epidemiology: Conceptual models, empirical challenges and interdisciplinary perspectives. International Journal of Epidemiology 2002, 31:285-293.
11. Bhugra D., Becker M.A. Migration, cultural bereavement and cultural identity. World Psychiatry 2005, 4:18-24.
12. Bonaiuto S., Rocca W.A., Lippi A., Giannandrea E., Mele M., Cavarzeran F., et al. Education and occupation as risk factors for dementia: A population-based case-control study. Neuroepidemiology 1995, 14:101-109.
13. Bosma H., van Boxtel M.P.J., Ponds R.W.H.M., Houx P.J., Burdorf A., Jolles J. Mental work demands protect against cognitive impairment: MAAS prospective cohort study. Experimental Aging Research 2003, 29:33-45.
14. Brainerd C.J., Reyna V.F., Petersen R.C., Smith G.E., Kenney A.E., Gross C.J., et al. The apolipoprotein E genotype predicts longitudinal transitions to mild cognitive impairment but not to Alzheimer's dementia: findings from a nationally representative study. Neuropsychology 2013, 27:86-94.
15. Chertkow H., Massoud F., Nasreddine Z., Belleville S., Joanette Y., Bocti C., et al. Diagnosis and treatment of dementia: 3. Mild cognitive impairment and cognitive impairment without dementia. Canadian Medical Association Journal 2008, 178:1273-1285.
16. Chuang Y.-F., Hayden K.M., Norton M.C., Tschanz J., Breitner J.C.S., Welsh-Bohmer K.A., et al. Association between APOE epsilon4 allele and vascular dementia: The Cache County study. Dementia and Geriatric Cognitive Disorders 2010, 29:248-253.
17. Davidson Y., Gibbons L., Purandare N., Byrne J., Hardicre J., Wren J., et al. Apolipoprotein E epsilon4 allele frequency in vascular dementia. Dementia and Geriatric Cognitive Disorders 2006, 22:15-19.
18. De Ronchi D., Berardi D., Menchetti M., Ferrari G., Serretti A., Dalmonte E., et al. Occurrence of cognitive impairment and dementia after the age of 60: A population-based study from Northern Italy. Dementia and Geriatric Cognitive Disorders 2005, 19:97-105.
19. De Ronchi D., Fratiglioni L., Rucci P., Paternicò A., Graziani S., Dalmonte E. The effect of education on dementia occurrence in an Italian population with middle to high socioeconomic status. Neurology 1998, 50:1231-1238.
20. DeCarli C. Mild cognitive impairment: Prevalence, prognosis, aetiology, and treatment. Lancet Neurology 2003, 2:15-21.
21. Di Carlo A., Lamassa M., Baldereschi M., Inzitari M., Scafato E., Farchi G., Inzitari D. CIND and MCI in the Italianelderly: frequency, vascularriskfactors, progression to dementia. Neurology 2007, 68:1909-1916.
22. Dubois B., Feldman H.H., Jacova C., Dekosky S.T., Barberger-Gateau P., Cummings J., et al. Research criteria for the diagnosis of Alzheimer's disease: Revising the NINCDS-ADRDA criteria. Lancet Neurology 2007, 6:734-746.
23. Editorial staff Report SVIMEZ: Population, education and the labor market and migration. Assistenza infermieristica e ricerca: AIR 2012, 31:158-162.
24. Fei M., Qu Y.C., Wang T., Yin J., Bai J.X., Ding Q.H. Prevalence and distribution of cognitive impairment no dementia (CIND) among the aged population and the analysis of socio-demographic characteristics: the community-based cross-sectional study. Alzheimer Disease and Associated Disorders 2009, 23:130-138.
25. Fratiglioni L., Paillard-Borg S., Winblad B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurology 2004, 3:343-353.
26. Fritsch T., McClendon M.J., Smyth K.A., Lerner A.J., Friedland R.P., Larsen J.D. Cognitive functioning in healthy aging: The role of reserve and lifestyle factors early in life. The Gerontologist 2007, 47:307-322.
27. Ganguli M., Dodge H.H., Shen C., DeKosky S.T. Mild cognitive impairment, amnestic type: An epidemiologic study. Neurology 2004, 63(1):115-121.
28. Guaita A., Colombo M., Vaccaro R., Fossi S., Vitali S.F., Forloni G., et al. Brain aging and dementia during the transition from late adulthood to old age: design and methodology of the ``Invece.Ab'' population-based study. BMC Geriatrics 2013, 13:98.
29. Gustavsson A., Svensson M., Jacobi F., Allgulander C., Alonso J., Beghi E., et al. Cost of disorders of the brain in Europe 2010. European Neuropsychopharmacology 2011, 21:718-779.
30. Håkansson K., Rovio S., Helkala E.-L., Vilska A.-R., Winblad B., Soininen H., et al. Association between mid-life marital status and cognitive function in later life: Population based cohort study. British Medical Journal 2009, 339:b2462.
31. Helmer C., Letenneur L., Rouch I., Richard-Harston S., Barberger-Gateau P., Fabrigoule C., et al. Occupation during life and risk of dementia in French elderly community residents. Journal of Neurology, Neurosurgery and Psychiatry 2001, 71:303-309.
32. Hort J., O'Brien J.T., Gainotti G., Pirttila T., Popescu B.O., Rektorova I., et al. EFNS guidelines for the diagnosis and management of Alzheimer's disease. European Journal of Neurology 2010, 17:1236-1248.
33. Hosmer D.W., Lemeshow S., Sturdivant R.X. Applied logistic regression. 2013, John Wiley & Sons, Hoboken, New Jersey; Canada. 3rd ed.
34. Karp A., Andel R., Parker M.G., Wang H.-X., Winblad B., Fratiglioni L. Mentally stimulating activities at work during midlife and dementia risk after age 75: Follow-up study from the Kungsholmen Project. American Journal of Geriatric Psychiatry 2009, 17:227-236.
35. Karp A., Kåreholt I., Qiu C., Bellander T., Winblad B., Fratiglioni L. Relation of education and occupation-based socioeconomic status to incident Alzheimer's disease. American Journal of Epidemiology 2004, 159:175-183.
36. Katz M.J., Lipton R.B., Hall C.B., Zimmerman M.E., Sanders A.E., Verghese J., et al. Age-specific and sex-specific prevalence and incidence of mild cognitive impairment, dementia, and Alzheimer dementia in blacks and whites: a report from the Einstein Aging Study. Alzheimer Disease and Associated Disorders 2012, 26:335-343.
37. Kim K.W., Youn J.-C., Han M.-K., Paik N.J., Lee T.J., Park J.H., et al. Lack of association between apolipoprotein E polymorphism and vascular dementia in Koreans. Journal of Geriatric Psychiatry and Neurology 2008, 21:12-17.
38. Koivisto K., Reinikainen K.J., Hänninen T., Vanhanen M., Helkala E.L., Mykkänen L., et al. Prevalence of age-associated memory impairment in a randomly selected population from eastern Finland. Neurology 1995, 45(4):741-747.
39. Kröger E., Andel R., Lindsay J., Benounissa Z., Verreault R., Laurin D. Is complexity of work associated with risk of dementia? The Canadian Study of Health And Aging. American Journal of Epidemiology 2008, 167:820-830.
40. Larner A.J. Comparing diagnostic accuracy of cognitive screening instruments: A weighted comparison approach. Dementia and Geriatric Cognitive Disorders Extra 2013, 3:60-65.
41. Launer L.J. Counting dementia: There is no one best way. Alzheimer's & Dementia: The Journal of Alzheimer's Association 2011, 7:10-14.
42. Lin H.-F., Lai C.-L., Tai C.-T., Lin R.-T., Liu C.-K. Apolipoprotein E polymorphism in ischemic cerebrovascular diseases and vascular dementia patients in Taiwan. Neuroepidemiology 2004, 23:129-134.
43. Lobo A., Launer L.J., Fratiglioni L., Andersen K., Di Carlo A., Breteler M.M., et al. Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000, 54:S4-S9.
44. Marengoni A., Fratiglioni L., Bandinelli S., Ferrucci L. Socioeconomic status during lifetime and cognitive impairment no-dementia in late life: The population-based aging in the Chianti Area (InCHIANTI) Study. Journal of Alzheimer's Disease: JAD 2011, 24:559-568.
45. McKay G.J., Silvestri G., Chakravarthy U., Dasari S., Fritsche L.G., Weber B.H., et al. Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. American Journal of Epidemiology 2011, 173:1357-1364.
46. McKeith I.G., Dickson D.W., Lowe J., Emre M., O'Brien J.T., Feldman H., et al. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB Consortium. Neurology 2005, 65:1863-1872.
47. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984, 34:939-944.
48. McNamee R. Efficiency of two-phase designs for prevalence estimation. International Journal of Epidemiology 2003, 32:1072-1078.
49. Meng X., D'Arcy C. Education and dementia in the context of the cognitive reserve hypothesis: A systematic review with meta-analyses and qualitative analyses. PLoS ONE 2012, 7:e38268.
50. Misiak B., Cialkowska-Kuzminska M., Frydecka D., Chladzinska-Kiejna S., Kiejna A. European studies on the prevalence of dementia in the elderly: Time for a step towards a methodological consensus. International Journal of Geriatric Psychiatry 2013, 28:1211-1221.
51. Moraes C., Pinto J.A., Lopes M.A., Litvoc J., Bottino C.M.C. Impact of sociodemographic and health variables on mini-mental state examination in a community-based sample of older people. European Archives of Psychiatry and Clinical Neurosciences 2010, 260:535-542.
52. Munoz D.G., Ganapathy G.R., Eliasziw M., Hachinski V. Educational attainment and socioeconomic status of patients with autopsy-confirmed Alzheimer disease. Archives of Neurology 2000, 57:85-89.
53. Persson G. Prevalence of mental disorders in a 70-year-old urban population. Acta Psychiatrica Scandinavica 1980, 62:119-139.
54. Petersen R.C. Mild cognitive impairment as a diagnostic entity. Journal of International Medicine 2004, 256:183-194.
55. Petersen R.C., Roberts R.O., Knopman D.S., Geda Y.E., Cha R.H., Pankratz V.S., et al. Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study of Aging. Neurology 2010, 75:889-897.
56. Potter G.G., Helms M.J., Plassman B.L. Associations of job demands and intelligence with cognitive performance among men in late life. Neurology 2008, 70:1803-1808.
57. Prencipe M., Casini A.R., Ferretti C., Lattanzio M.T., Fiorelli M., Culasso F. Prevalence of dementia in an elderly rural population: Effects of age, sex, and education. Journal of Neurology, Neurosurgery and Psychiatry 1996, 60:628-633.
58. Prince M. Commentary: Two-phase surveys. A death is announced; no flowers please. International Journal of Epidemiology 2003, 32:1078-1080.
59. Prince M., Bryce R., Albanese E., Wimo A., Ribeiro W., Ferri C.P. The global prevalence of dementia: A systematic review and metaanalysis. Alzheimer's & Dementia: The Journal of Alzheimer's Association 2013, 9:63-75.
60. Ravaglia G., Forti P., Maioli F., Sacchetti L., Mariani E., Nativio V., et al. Education, occupation, and prevalence of dementia: Findings from the Conselice study. Dementia and Geriatric Cognitive Disorders 2002, 14:90-100.
61. Ravaglia G., Forti P., Montesi F., Lucicesare A., Pisacane N., Rietti E., et al. Mild cognitive impairment: Epidemiology and dementia risk in an elderly Italian population. Journal of the American Geriatrics Society 2008, 56:51-58.
62. Rocca W.A., Bonaiuto S., Lippi A., Luciani P., Turtù F., Cavarzeran F., et al. Prevalence of clinically diagnosed Alzheimer's disease and other dementing disorders: A door-to-door survey in Appignano, Macerata Province, Italy. Neurology 1990, 40:626-631.
63. Rosen H.J., Hartikainen K.M., Jagust W., Kramer J.H., Reed B.R., Cummings J.L., et al. Utility of clinical criteria in differentiating frontotemporal lobar degeneration (FTLD) from AD. Neurology 2002, 58:1608-1615.
64. Sacuiu S., Gustafson D., Sjögren M., Guo X., Ostling S., Johansson B., et al. Secular changes in cognitive predictors of dementia and mortality in 70-year-olds. Neurology 2010, 75:779-785.
65. Sadigh-Eteghad S., Talebi M., Farhoudi M. Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer's disease. A meta-analysis. Neurosciences (Riyadh) 2012, 17:321-326.
66. Saunders A.M., Strittmatter W.J., Schmechel D., George-Hyslop P.H., Pericak-Vance M.A., Joo S.H., et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993, 43:1467-1472.
67. Schoenmaker N., Van Gool W.A. The age gap between patients in clinical studies and in the general population: a pitfall for dementia research. Lancet Neurology 2004, 3:627-630.
68. Sharp E.S., Gatz M. Relationship between education and dementia: An updated systematic review. Alzheimer Disease and Associated Disorders 2011, 25:289-304.
69. Smyth K.A., Fritsch T., Cook T.B., McClendon M.J., Santillan C.E., Friedland R.P. Worker functions and traits associated with occupations and the development of AD. Neurology 2004, 63:498-503.
70. Solfrizzi V., Panza F., Colacicco A.M., D'Introno A., Capurso C., Torres F., et al. Vascular risk factors, incidence of MCI, and rates of progression to dementia. Neurology 2004, 63:1882-1891.
71. Spinnler H., Tognoni G. Italian standardization and classification of Neuropsychological tests. The Italian Group on the Neuropsychological Study of Aging. Italian Journal of Neurological Sciences 1987, (Suppl. 8):1-120.
72. Takata Y., Shimada M., Ansai T., Yoshitake Y., Nishimuta M., Nakagawa N., et al. Physical performance and 10-year mortality in a 70-year-old community-dwelling population. Aging Clinical and Experimental Research 2012, 24:257-264.
73. Tognoni G., Ceravolo R., Nucciarone B., Bianchi F., Dell'Agnello G., Ghicopulos I., et al. From mild cognitive impairment to dementia: A prevalence study in a district of Tuscany, Italy. Acta Neurologica Scandinavica 2005, 112:65-71.
74. Waidmann T.A., Liu K. Disability trends among elderly persons and implications for the future. The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences 2000, 55:S298-S307.
75. Ward A., Arrighi H.M., Michels S., Cedarbaum J.M. Mild cognitive impairment: disparity of incidence and prevalence estimates. Alzheimer's & Dementia: The Journal of Alzheimer's Association 2012, 8:14-21.
76. Wiederkehr S., Simard M., Fortin C., van Reekum R. Validity of the clinical diagnostic criteria for vascular dementia: A critical review. Part II. The Journal of Neuropsychiatry and Clinical Neurosciences 2008, 20:162-177.
77. Wimo A., Jönsson L., Bond J., Prince M., Winblad B. The worldwide economic impact of dementia 2010. Alzheimer's & Dementia: The Journal of Alzheimer's Association 2013, 9:1-11.