Cognitive impairment after age 60: Clinical and social correlates in the "faenza Project"

Journal of Alzheimer's Disease

Volumn 21, Issue 4, 2010, Pages 1325-1334

  Atti, Anna Rita ^a,b   Forlani, Claudia ^b   De Ronchi, Diana ^b   Palmer, Katie ^c   Casadio, Paola ^b   Dalmonte, Edoardo ^d   Fratiglioni, Laura ^a,e  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^d Unit of Geriatric Medicine   (Italy)

^e STOCKHOLM GERONTOLOGY RESEARCH CENTER   (Sweden)

Author keywords

Cognitive impairment; cognitive impairment no dementia (CIND); comorbidity; depression; diabetes; epidemiology; stroke

Indexed keywords

ADULT; AGED; AGING; ANXIETY DISORDER; ARTICLE; CARDIOVASCULAR DISEASE; CLINICAL FEATURE; COGNITION; COGNITIVE DEFECT; COGNITIVE IMPAIRMENT NO DEMENTIA; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEMENTIA; DEPRESSION; DIABETES MELLITUS; DIAGNOSTIC PROCEDURE; EDUCATIONAL STATUS; FEMALE; GENDER; HUMAN; HYPERTENSION; ITALY; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; NURSE; OBESITY; PHYSICIAN; POPULATION BASED CASE CONTROL STUDY; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; SCORING SYSTEM; SOCIAL ASPECT; SOCIOECONOMICS; STROKE; UNDERWEIGHT;

EID: 78650441300     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-091618     Document Type: Article

References (54)

1. Graham JE, Rockwood K, Beattie BL, Eastwood R, Gauthier S, Tuokko H, McDowell I (1997) Prevalence and severity of cognitive impairment with and without dementia in an elderly population. Lancet 349, 1793-1796.
2. Ebly EM, Hogan DB, Parhad IM (1995) Cognitive impairment in the nondemented elderly. Results from the Canadian Study of Health and Aging. Arch Neurol 52, 612-619.
3. Feldman H, Levy AR, Hsiung GY, Peters KR, Donald A, Black SE, Bouchard RW, Gauthier SG, Guzman DA, Hogan DB, Kertesz A, Rockwood K; ACCORD Study Group (2003) A Canadian cohort study of cognitive impairment and related dementias (ACCORD): study methods and baseline results. Neuroepidemiology 22, 265-274.
4. Low LF, Brodaty H, Edwards R, Kochan N, Draper B, Trollor J, Sachdev P (2004) The prevalence of "cognitive impairment no dementia" in community-dwelling elderly: a pilot study. AustNZJPsychiatry 38, 725-731.
5. Baiyewu O, Unverzagt FW, Ogunniyi A, Hall KS, Gureje O, Gao S, Lane KA, Hendrie HC (2002) Cognitive impairment in community-dwelling older Nigerians: clinical correlates and stability of diagnosis. Eur J Neurol 9, 573-580.
6. Unverzagt FW, Gao S, Baiyewu O, Ogunniyi AO, Gureje O, Perkins A, Emsley CL, Dickens J, Evans R, Musick B, Hall KS, Hui SL, Hendrie HC (2001) Prevalence of cognitive impairment: data from the Indianapolis Study of Health and Aging. Neurology 57, 1655-1662.
7. Di Carlo A, Lamassa M, Baldereschi M, Inzitari M, Scafato E, Farchi G, Inzitari D (2007) CIND and MCI in the Italian elderly: frequency, vascular risk factors, progression to dementia. Neurology 68, 1909-1916.
8. Plassman BL, Langa KM, Fisher GG, Heeringa SG, Weir DR, Ofstedal MB, Burke JR, Hurd MD, Potter GG, Rodgers WL, Steffens DC, McArdle JJ, Willis RJ, Wallace RB (2008) Prevalence of cognitive impairment without dementia in the United States. Ann Intern Med 148, 427-434.
9. Choo IH, Lee DY, Lee JH, Kim KW, Jhoo JH, Ju YS, Yoon JC, Kim SG, Ha J, Woo JI (2009) The prevalence of cognitive impairment with no dementia in older people: the Seoul study. Int J Geriatr Psychiatry 24, 306-312.
10. De Ronchi D, Berardi D, Menchetti M, Ferrari G, Serretti A, Dal monte E, Fratiglioni L (2005) Occurrence of cognitive impairment and dementia after the age of 60: a population-based study from Northern Italy. Dement Geriatr Cogn Disord 19, 97-105.
11. Kim O (2009) Cognitive impairment and depression in community-dweller older Korean women. Psychol Rep 105, 569-574.
12. Gavrila D, Antiinez C, Tormo MJ, Carles R, Garcia Santos JM, Parrilla G, Fortuna L, Jimenez J, Salmeron D, Navarro C (2009) Prevalence of dementia and cognitive impairment in Southeastern Spain: the Ariana Study. Acta Neurol Scand 120, 300-307.
13. Fei M, Qu JC, Wang T, Yin J, Bai JX, Ding QH (2009) Prevalence and distribution of cognitive impairment no dementia (CIND) among the aged population and the analysis of socio-demographic characteristics: the community-based cross-sectional study. Alzheimer Dis Assoc Disord 23, 130138.
14. Caracciolo B, Palmer K, Monastero R, Winblad B, Beckman L, Fratiglioni L (2008) Occurrence of cognitive impairment and dementia in the community: a 9-year-long prospective study. Neurology 70, 1778-1785.
15. Palmer K, Wang HX, Backman L, Winblad B, Fratiglioni L (2002) Differential evolution of cognitive impairment in nondemented older persons: results from the Kungsholmen Project. Am J Psychiatry 159, 436-442.
16. Frank L, Lloyd A, Flynn JA, Kleinman L, Matza LS, Mar-golis MK, Bowman L, Bullock R (2006) Impact of cognitive impairment on mild dementia patients and mild cognitive impairment patients and their informants. Int Psychogeriatr 18, 151-162.
17. Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198.
18. Lyketsos CG, Toone L, Tschanz J, Rabins PV, Steinberg M, Onyike CU, Corcoran C, Norton M, Zandi P, Breitner JC, Welsh-Bohmer K, Anthony J, 0stbye T, Bigler E, Pieper C, Burke J, Plassman B, Green RC, Steffens DC, Klein L, Leslie C, Townsend JJ, Wyse BW, Munger R, Williams M; Cache County Study Group (2005) Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County Study. Am J Geriatr Psychiatry 13, 656-664.
19. Lyketsos CG, Lopez O, Jones B, Fitzpatrick AL, Breitner J, DeKosky S (2002) Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA 288, 1475-1483.
20. De Ronchi D, Palmer K, Pioggiosi P, Atti AR, Berardi D, Ferrari B, Dalmonte E, Fratiglioni L (2007) The combined effect of age, education, and stroke on dementia and cognitive impairment no dementia in the elderly. Dement Geriatr Cogn Disord 24, 266-273.
21. Di Carlo A, Baldereschi M, Amaducci L, Maggi S, Grigoletto F, Scarlato G, Inzitari D (2000) Cognitive impairment without dementia in older people: prevalence, vascular risk factors, impact on disability. The Italian Longitudinal Study on Aging. J Am Geriatr Soc 48, 775-782.
22. Elias PK, Elias MF, D'Agostino RB, Silbershatz H, Wolf PA (1999) Alcohol consumption and cognitive performance in the Framingham Heart Study. Am J Epidemiol 150, 580-589.
23. Anttila T, Helkala EL, Viitanen M, Kareholt I, Fratiglioni L, Winblad B, Soininen H, Tuomilehto J, Nissinen A, Kivipelto M (2004) Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study. BMJ 329, 539.
24. Almeida OP, Garrido GJ, Lautenschlager NT, Hulse GK, Jam-rozik K, Flicker L (2008) Smoking is associated with reduced cortical regional gray matter density in brain regions associated with incipient Alzheimer disease. Am J Geriatr Psychiatry 16, 92-98.
25. Reisberg B, Ferris SH, de Leon MJ, Crook T (1982) The Global Deterioration Scale for assessment of primary degenerative dementia. Am J Psychiatry 139, 1136-1139.
26. American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders. Third edition revised (DSM-III-R), Washington, DC.
27. Magni E, Binetti G, Cappa S, Bianchetti A, Trabucchi M (1995) Effect of age and education on performance on the Mini-Mental State Examination in a healthy older population and during the course of Alzheimer's disease. J Am Geriatr Soc 43, 942-943.
28. De Ronchi D, Fratiglioni L, Rucci P, Paternico A, Graziani S, Dalmonte E (1998) The effect of education on dementia occurrence in an Italian population with middle to high socioeconomic status. Neurology 50, 1231-1238.
29. Karp A, Kareholt I, Qiu C, Bellander T, Winblad B, Fratiglioni L (2004) Relation of education and occupation-based socioeconomic status to incident Alzheimer's disease. Am J Epidemiol 159, 175-183.
30. World Health Organization (1987) International classification of disease, injuries and causes of death. Ninth revision (ICD-9), Geneva.
31. World Health Organization (1998) Report of WHO consultation on obesity. Obesity: preventing and managing the global epidemic, Geneva.
32. Lee S, Kawachi I, Berkman LF, Grodstein F (2003) Education, other socioeconomic indicators, and cognitive function. Am J Epidemiol 157, 712-720.
33. Fratiglioni L, Wang HX (2007) Brain reserve hypothesis in dementia. JAlzheimers Dis 12, 11-22.
34. Evans DA, Hebert LE, Beckett LA, Scherr PA, Albert MS, Chown MJ, Pilgrim DM, Taylor JO (1997) Education and other measures of socioeconomic status and risk of incident Alzheimer disease in a defined population of older persons. Arch Neurol 54, 1399-1405.
35. Hakansson K, Rovio S, Helkala EL, Vilska AR, Winblad B, Soininen H, Nissinen A, Mohammed AH, Kivipelto M (2009) Association between mid-life marital status and cognitive function in later life: population based cohort study. BMJ 339, 2462.
36. Wilson RS, Hebert LE, Scherr PA, Barnes LL, Mendes de Leon CF, Evans DA (2009) Educational attainment and cognitive decline in old age. Neurology 72, 460-465.
37. Stinson FS, Dawson DA, Goldstein RB, Chou SP, Huang B, Smith SM, Ruan WJ, Pulay AJ, Saha TD, Pickering RP, Grant BF (2008) Prevalence, correlates, disability, and comorbidity of DSM-IV narcissistic personality disorder: results from the wave 2 national epidemiologic survey on alcohol and related conditions. J Clin Psychiatry 69, 1033-1045. (Pubitemid 352031585)
38. Grant BF, Chou SP, Goldstein RB, Huang B, Stinson FS, Saha TD, Smith SM, Dawson DA, Pulay AJ, Pickering RP, Ruan WJ (2008) Prevalence, correlates, disability, and comorbidity of DSM-IV borderline personality disorder: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 69, 533-545. (Pubitemid 351792327)
39. Torgersen S, Kringlen E, Cramer V (2001). The prevalence of personality disorders in a community sample. Arch Gen Psychiatry 58, 590-596.
40. Meins W, Dammast J (2000) Do personality traits predict the occurrence of Alzheimer's disease? Int J Geriatr Psychiatry 15, 120-124.
41. Wang HX, Karp A, Herlitz A, Crowe M, Kareholt I, Winblad B, Fratiglioni L (2009) Personality and lifestyle in relation to dementia incidence. Neurology 72, 253-259.
42. Srikanth VK, Thrift AG, Saling MM, Anderson JF, Dewey HM, Macdonell RA, Donnan GA (2003) Community-Based Prospective Study of Nonaphasic English-Speaking Survivors. Increased risk of cognitive impairment 3 months after mild to moderate first-ever stroke: a Community-Based Prospective Study of Nonaphasic English-Speaking Survivors. Stroke 34, 1136-1143.
43. Steffens DC, Otey E, Alexopoulos GS, Butters MA, Cuthbert B, Ganguli M, Geda YE, Hendrie HC, Krishnan RR, Kumar A, Lopez OL, Lyketsos CG, Mast BT, Morris JC, Norton MC, Peavy GM, Petersen RC, Reynolds CF, Salloway S, Welsh-Bohmer KA, Yesavage J (2006) Perspectives on Depression, Mild Cognitive Impairment, and Cognitive Decline. Arch Gen Psychiatry 63, 130-138. (Pubitemid 43213874)
44. Barnes DE, Alexopoulos GS, Lopez OL, Williamson JD, Yaffe K (2006) Depressive symptoms, vascular disease, and mild cognitive impairment: findings from the Cardiovascular Health Study. Arch Gen Psychiatry 63, 273-279.
45. Strachan MW, Price JF, Frier BM (2008) Diabetes, cognitive impairment, and dementia BMJ 336, 7634-7636.
46. MacKnight C, Rockwood K, Awalt E, McDowell I (2002) Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging. Dement Geriatr Cogn Disord 14, 77-83. (Pubitemid 36152948)
47. Xu W, Qiu C, Gatz M, Pedersen NL, Johansson B, Fratiglioni L (2009) Mid-and late-life diabetes in relation to the risk of dementia: a population-based twin study. Diabetes 58, 71-77.
48. Alexopoulos GS (2006) The vascular depression hypothesis: 10 years later 2006. Biol Psychiatry 15, 1304-1305.
49. Luchsinger JA, Honig LS, Tang MX, Devanand DP (2008) Depressive symptoms, vascular risk factors, and Alzheimer's disease. Int J Geriatr Psychiatry 23, 922-928.
50. Prencipe M, Santini M, Casini AR, Pezzella FR, Scaldaferri N, Culasso F (2003) Prevalence of non-dementing cognitive disturbances and their association with vascular risk factors in an elderly population. J Neurol 250, 907-912.
51. Qiu C, Winblad B, Fratiglioni L (2005) The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol 4, 487-499.
52. Mariani E, Monastero R, Mecocci P (2007) Mild cognitive impairment: a systematic review. J Alzheimers Dis 12, 23-35.
53. Monastero R, Mangialasche F, Camarda C, Ercolani S, Camar-da R (2009) A systematic review of neuropsychiatric symptoms in mild cognitive impairment. J Alzheimers Dis 18, 1130.
54. Nasreddine ZS, Phillips NA, Bedirian V, Charbonneau S, Whitehead V, Collin I, Cummings JL, Chertkow H (2005) The Montreal Cognitive Assessment (MoCA): A briefscreen-ing tool for mild cognitive impairment. J Am Geriatr Soc 53, 695-699.