γ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition

Oncotarget

Volumn 6, Issue 4, 2015, Pages 2180-2192

  Xiao, Heng ^a,b   Tong, Rongliang ^a,b   Ding, Chaofeng ^a,b   Lv, Zhen ^a,b   Du, Chengli ^a,b   Peng, Chuanhui ^a,b   Cheng, Shaobing ^a,b   Xie, Haiyang ^b   Zhou, Lin ^b   Wu, Jian ^a,b   Zheng, Shusen ^a,b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Epidermal growth factor receptor(EGFR); Hepatocellular carcinoma (HCC); Hypoxia inducible factor 1a (HIF 1 ); Vascular endothelial growth factor (VEGF); H2AX; angiogenesis

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HISTONE H2AX; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; VASCULOTROPIN; H2AFX PROTEIN, HUMAN; HISTONE; TRANSCRIPTOME; VASCULOTROPIN A;

ADULT; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CONTROLLED STUDY; FEMALE; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN MICROARRAY; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR INVASION; TUMOR VOLUME; ANIMAL; CELL HYPOXIA; CONFOCAL MICROSCOPY; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; IMMUNOHISTOCHEMISTRY; KAPLAN MEIER METHOD; LIVER TUMOR; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); SCID MOUSE; TUMOR CELL LINE; VASCULARIZATION; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL HYPOXIA; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HISTONES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; LIVER NEOPLASMS; LIVER TRANSPLANTATION; MICE, SCID; MICROSCOPY, CONFOCAL; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TRANSPLANTATION, HETEROLOGOUS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84922980166     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2942     Document Type: Article

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