메뉴 건너뛰기




Volumn 21, Issue 3, 2015, Pages 402-411

Will Post-Transplantation Cell Therapies for Pediatric Patients Become Standard of Care?

Author keywords

Adoptive cellular therapy; Chimeric antigen receptor; Pediatrics; Stem cell transplantation

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADOPTIVE IMMUNOTHERAPY; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; CELL THERAPY; CHILDHOOD CANCER; CYTOKINE INDUCED KILLER CELL; CYTOTOXIC T LYMPHOCYTE; DONOR LYMPHOCYTE INFUSION; GRAFT FAILURE; GRAFT VERSUS HOST REACTION; GRAFT VERSUS LEUKEMIA EFFECT; HEALTH CARE QUALITY; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC CELL; HOST; HUMAN; IMMUNE SYSTEM; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; REGULATORY T LYMPHOCYTE; REVIEW; SELF CONCEPT; STEM CELL TRANSPLANTATION; ADOLESCENT; ALLOGRAFT; BIOLOGICAL THERAPY; CHILD; FEMALE; GRAFT REJECTION; GRAFT VERSUS TUMOR EFFECT; GRAFT VS HOST DISEASE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGY; INFANT; LYMPHOCYTE TRANSFUSION; MALE; PATHOLOGY; PRESCHOOL CHILD; PROCEDURES;

EID: 84922894713     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2014.07.018     Document Type: Review
Times cited : (9)

References (130)
  • 1
    • 84892471446 scopus 로고    scopus 로고
    • The time is now: moving toward virus-specific T cells after allogeneic hematopoietic stem cell transplantation as the standard of care
    • Saglio F., Hanley P.J., Bollard C.M. The time is now: moving toward virus-specific T cells after allogeneic hematopoietic stem cell transplantation as the standard of care. Cytotherapy 2014, 16:149-159.
    • (2014) Cytotherapy , vol.16 , pp. 149-159
    • Saglio, F.1    Hanley, P.J.2    Bollard, C.M.3
  • 2
    • 77649221824 scopus 로고    scopus 로고
    • Long-term outcome of EBV-specific T cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
    • Heslop H.E., Slobod K.S., Pule M.A., et al. Long-term outcome of EBV-specific T cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients. Blood 2010, 115:925-935.
    • (2010) Blood , vol.115 , pp. 925-935
    • Heslop, H.E.1    Slobod, K.S.2    Pule, M.A.3
  • 3
    • 0032170108 scopus 로고    scopus 로고
    • Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients
    • Rooney C.M., Smith C.A., Ng C.Y., et al. Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients. Blood 1998, 92:1549-1555.
    • (1998) Blood , vol.92 , pp. 1549-1555
    • Rooney, C.M.1    Smith, C.A.2    Ng, C.Y.3
  • 4
    • 0029924619 scopus 로고    scopus 로고
    • Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes
    • Heslop H.E., Ng C.Y., Li C., et al. Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes. Nat Med 1996, 2:551-555.
    • (1996) Nat Med , vol.2 , pp. 551-555
    • Heslop, H.E.1    Ng, C.Y.2    Li, C.3
  • 5
    • 0028816546 scopus 로고
    • Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr virus-related lymphoproliferation
    • Rooney C.M., Smith C.A., Ng C.Y., et al. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr virus-related lymphoproliferation. Lancet 1995, 345:9-13.
    • (1995) Lancet , vol.345 , pp. 9-13
    • Rooney, C.M.1    Smith, C.A.2    Ng, C.Y.3
  • 6
    • 0028288519 scopus 로고
    • Infusions of donor leukocytes to treat Epstein-Barr virus-associated lymphoproliferative disorders after allogeneic bone marrow transplantation
    • Papadopoulos E.B., Ladanyi M., Emanuel D., et al. Infusions of donor leukocytes to treat Epstein-Barr virus-associated lymphoproliferative disorders after allogeneic bone marrow transplantation. NEngl J Med 1994, 330:1185-1191.
    • (1994) NEngl J Med , vol.330 , pp. 1185-1191
    • Papadopoulos, E.B.1    Ladanyi, M.2    Emanuel, D.3
  • 7
    • 0027990846 scopus 로고
    • Donor T cells to treat EBV-associated lymphoma
    • Heslop H.E., Brenner M.K., Rooney C.M. Donor T cells to treat EBV-associated lymphoma. NEngl J Med 1994, 331:679-680.
    • (1994) NEngl J Med , vol.331 , pp. 679-680
    • Heslop, H.E.1    Brenner, M.K.2    Rooney, C.M.3
  • 8
    • 84858683311 scopus 로고    scopus 로고
    • + lymphomas after allogeneic hematopoietic cell transplantation
    • + lymphomas after allogeneic hematopoietic cell transplantation. Blood 2012, 119:2644-2656.
    • (2012) Blood , vol.119 , pp. 2644-2656
    • Doubrovina, E.1    Oflaz-Sozmen, B.2    Prockop, S.E.3
  • 9
    • 0032525146 scopus 로고    scopus 로고
    • Semiquantitative Epstein-Barr virus (EBV) polymerase chain reaction for the determination of patients at risk for EBV-induced lymphoproliferative disease after stem cell transplantation
    • Lucas K.G., Burton R.L., Zimmerman S.E., et al. Semiquantitative Epstein-Barr virus (EBV) polymerase chain reaction for the determination of patients at risk for EBV-induced lymphoproliferative disease after stem cell transplantation. Blood 1998, 91:3654-3661.
    • (1998) Blood , vol.91 , pp. 3654-3661
    • Lucas, K.G.1    Burton, R.L.2    Zimmerman, S.E.3
  • 10
    • 34248659404 scopus 로고    scopus 로고
    • Preemptive therapy of EBV-related lymphoproliferative disease after pediatric haploidentical stem cell transplantation
    • Comoli P., Basso S., Zecca M., et al. Preemptive therapy of EBV-related lymphoproliferative disease after pediatric haploidentical stem cell transplantation. Am J Transplant 2007, 7:1648-1655.
    • (2007) Am J Transplant , vol.7 , pp. 1648-1655
    • Comoli, P.1    Basso, S.2    Zecca, M.3
  • 11
    • 84871760755 scopus 로고    scopus 로고
    • Adoptive transfer of Epstein-Barr virus (EBV) nuclear antigen 1-specific T cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem cell transplantation
    • Icheva V., Kayser S., Wolff D., et al. Adoptive transfer of Epstein-Barr virus (EBV) nuclear antigen 1-specific T cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem cell transplantation. JClin Oncol 2012, 31:39-48.
    • (2012) JClin Oncol , vol.31 , pp. 39-48
    • Icheva, V.1    Kayser, S.2    Wolff, D.3
  • 12
    • 77951058615 scopus 로고    scopus 로고
    • Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells
    • Moosmann A., Bigalke I., Tischer J., et al. Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells. Blood 2010, 115:2960-2970.
    • (2010) Blood , vol.115 , pp. 2960-2970
    • Moosmann, A.1    Bigalke, I.2    Tischer, J.3
  • 13
    • 73349108055 scopus 로고    scopus 로고
    • Anovel haplo-identical adoptive CTL therapy as a treatment for EBV-associated lymphoma after stem cell transplantation
    • Uhlin M., Okas M., Gertow J., et al. Anovel haplo-identical adoptive CTL therapy as a treatment for EBV-associated lymphoma after stem cell transplantation. Cancer Immunol Immunother 2010, 59:473-477.
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 473-477
    • Uhlin, M.1    Okas, M.2    Gertow, J.3
  • 14
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
    • Walter E.A., Greenberg P.D., Gilbert M.J., et al. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. NEngl J Med 1995, 333:1038-1044.
    • (1995) NEngl J Med , vol.333 , pp. 1038-1044
    • Walter, E.A.1    Greenberg, P.D.2    Gilbert, M.J.3
  • 15
    • 0026648439 scopus 로고
    • Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones
    • Riddell S.R., Watanabe K.S., Goodrich J.M., et al. Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science 1992, 257:238-241.
    • (1992) Science , vol.257 , pp. 238-241
    • Riddell, S.R.1    Watanabe, K.S.2    Goodrich, J.M.3
  • 16
    • 23744516707 scopus 로고    scopus 로고
    • Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers
    • Cobbold M., Khan N., Pourgheysari B., et al. Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers. JExp Med 2005, 202:379-386.
    • (2005) JExp Med , vol.202 , pp. 379-386
    • Cobbold, M.1    Khan, N.2    Pourgheysari, B.3
  • 17
    • 0036624737 scopus 로고    scopus 로고
    • Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy
    • Einsele H., Roosnek E., Rufer N., et al. Infusion of cytomegalovirus (CMV)-specific T cells for the treatment of CMV infection not responding to antiviral chemotherapy. Blood 2002, 99:3916-3922.
    • (2002) Blood , vol.99 , pp. 3916-3922
    • Einsele, H.1    Roosnek, E.2    Rufer, N.3
  • 18
    • 78549241330 scopus 로고    scopus 로고
    • Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation
    • Feuchtinger T., Opherk K., Bethge W.A., et al. Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation. Blood 2010, 116:4360-4367.
    • (2010) Blood , vol.116 , pp. 4360-4367
    • Feuchtinger, T.1    Opherk, K.2    Bethge, W.A.3
  • 19
    • 84887501471 scopus 로고    scopus 로고
    • Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant
    • Gerdemann U., Katari U.L., Papadopoulou A., et al. Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant. Mol Ther 2013, 21:2113-2121.
    • (2013) Mol Ther , vol.21 , pp. 2113-2121
    • Gerdemann, U.1    Katari, U.L.2    Papadopoulou, A.3
  • 21
    • 34248638783 scopus 로고    scopus 로고
    • Exvivo expansion and prophylactic infusion of CMV-pp65 peptide-specific cytotoxic T-lymphocytes following allogeneic hematopoietic stem cell transplantation
    • Micklethwaite K., Hansen A., Foster A., et al. Exvivo expansion and prophylactic infusion of CMV-pp65 peptide-specific cytotoxic T-lymphocytes following allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2007, 13:707-714.
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 707-714
    • Micklethwaite, K.1    Hansen, A.2    Foster, A.3
  • 22
    • 79951655904 scopus 로고    scopus 로고
    • Directly selected cytomegalovirus-reactive donor T cells confer rapid and safe systemic reconstitution of virus-specific immunity following stem cell transplantation
    • Peggs K.S., Thomson K., Samuel E., et al. Directly selected cytomegalovirus-reactive donor T cells confer rapid and safe systemic reconstitution of virus-specific immunity following stem cell transplantation. Clin Infect Dis 2011, 52:49-57.
    • (2011) Clin Infect Dis , vol.52 , pp. 49-57
    • Peggs, K.S.1    Thomson, K.2    Samuel, E.3
  • 23
    • 28844459420 scopus 로고    scopus 로고
    • Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation
    • Perruccio K., Tosti A., Burchielli E., et al. Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation. Blood 2005, 106:4397-4406.
    • (2005) Blood , vol.106 , pp. 4397-4406
    • Perruccio, K.1    Tosti, A.2    Burchielli, E.3
  • 24
    • 15944424571 scopus 로고    scopus 로고
    • Generation of CMV-specific T lymphocytes using protein-spanning pools of pp65-derived overlapping pentadecapeptides for adoptive immunotherapy
    • Trivedi D., Williams R.Y., O'Reilly R.J., et al. Generation of CMV-specific T lymphocytes using protein-spanning pools of pp65-derived overlapping pentadecapeptides for adoptive immunotherapy. Blood 2005, 105:2793-2801.
    • (2005) Blood , vol.105 , pp. 2793-2801
    • Trivedi, D.1    Williams, R.Y.2    O'Reilly, R.J.3
  • 25
    • 0027998850 scopus 로고
    • Donor leukocyte infusion as therapy of life-threatening adenoviral infections after T-cell-depleted bone marrow transplantation
    • Hromas R., Cornetta K., Srour E., et al. Donor leukocyte infusion as therapy of life-threatening adenoviral infections after T-cell-depleted bone marrow transplantation. Blood 1994, 84:1689-1690.
    • (1994) Blood , vol.84 , pp. 1689-1690
    • Hromas, R.1    Cornetta, K.2    Srour, E.3
  • 26
    • 33744788680 scopus 로고    scopus 로고
    • Safe adoptive transfer of virus-specific T-cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation
    • Feuchtinger T., Matthes-Martin S., Richard C., et al. Safe adoptive transfer of virus-specific T-cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation. Br J Haematol 2006, 134:64-76.
    • (2006) Br J Haematol , vol.134 , pp. 64-76
    • Feuchtinger, T.1    Matthes-Martin, S.2    Richard, C.3
  • 27
    • 84864547457 scopus 로고    scopus 로고
    • Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections
    • Gerdemann U., Keirnan J.M., Katari U.L., et al. Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections. Mol Ther 2012, 20:1622-1632.
    • (2012) Mol Ther , vol.20 , pp. 1622-1632
    • Gerdemann, U.1    Keirnan, J.M.2    Katari, U.L.3
  • 28
    • 74949113395 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation
    • Leen A.M., Christin A., Myers G.D., et al. Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation. Blood 2009, 114:4283-4292.
    • (2009) Blood , vol.114 , pp. 4283-4292
    • Leen, A.M.1    Christin, A.2    Myers, G.D.3
  • 29
    • 84903752045 scopus 로고    scopus 로고
    • Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT
    • Papadopoulou A., Gerdemann U., Katari U.L., et al. Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT. Sci Transl Med 2014, 6:1-11.
    • (2014) Sci Transl Med , vol.6 , pp. 1-11
    • Papadopoulou, A.1    Gerdemann, U.2    Katari, U.L.3
  • 30
    • 77951036524 scopus 로고    scopus 로고
    • Allo-HLA reactivity of virus-specific memory T cells is common
    • Amir A.L., D'Orsogna L.J., Roelen D.L., et al. Allo-HLA reactivity of virus-specific memory T cells is common. Blood 2010, 115:3146-3157.
    • (2010) Blood , vol.115 , pp. 3146-3157
    • Amir, A.L.1    D'Orsogna, L.J.2    Roelen, D.L.3
  • 31
    • 77958000233 scopus 로고    scopus 로고
    • Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects
    • Melenhorst J.J., Leen A.M., Bollard C.M., et al. Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects. Blood 2010, 116:4700-4702.
    • (2010) Blood , vol.116 , pp. 4700-4702
    • Melenhorst, J.J.1    Leen, A.M.2    Bollard, C.M.3
  • 32
    • 70349247010 scopus 로고    scopus 로고
    • Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes
    • Hanley P.J., Cruz C.R., Savoldo B., et al. Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes. Blood 2009, 114:1958-1967.
    • (2009) Blood , vol.114 , pp. 1958-1967
    • Hanley, P.J.1    Cruz, C.R.2    Savoldo, B.3
  • 33
    • 84884178203 scopus 로고    scopus 로고
    • Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation
    • Leen A.M., Bollard C.M., Mendizabal A.M., et al. Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation. Blood 2013, 121:5113-5123.
    • (2013) Blood , vol.121 , pp. 5113-5123
    • Leen, A.M.1    Bollard, C.M.2    Mendizabal, A.M.3
  • 34
    • 84898647949 scopus 로고    scopus 로고
    • Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins
    • Bollard C.M., Gottschalk S., Torrano V., et al. Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins. JClin Oncol 2014, 32:798-808.
    • (2014) JClin Oncol , vol.32 , pp. 798-808
    • Bollard, C.M.1    Gottschalk, S.2    Torrano, V.3
  • 35
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn G.P., Old L.J., Schreiber R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004, 21:137-148.
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 36
    • 0037448371 scopus 로고    scopus 로고
    • Immunosurveillance against cancer and immunotherapy-synergy or antagonism?
    • Boon T., van Baren N. Immunosurveillance against cancer and immunotherapy-synergy or antagonism?. NEngl J Med 2003, 348:252-254.
    • (2003) NEngl J Med , vol.348 , pp. 252-254
    • Boon, T.1    van Baren, N.2
  • 37
    • 48149104816 scopus 로고    scopus 로고
    • Spontaneous immune responses to sporadic tumors: tumor-promoting, tumor-protective or both?
    • de Visser K.E. Spontaneous immune responses to sporadic tumors: tumor-promoting, tumor-protective or both?. Cancer Immunol Immunother 2008, 57:1531-1539.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1531-1539
    • de Visser, K.E.1
  • 38
    • 70350719347 scopus 로고    scopus 로고
    • Interferon-gamma-dependent infiltration of human T cells into neuroblastoma tumors invivo
    • Reid G.S., Shan X., Coughlin C.M., et al. Interferon-gamma-dependent infiltration of human T cells into neuroblastoma tumors invivo. Clin Cancer Res 2009, 15:6602-6608.
    • (2009) Clin Cancer Res , vol.15 , pp. 6602-6608
    • Reid, G.S.1    Shan, X.2    Coughlin, C.M.3
  • 39
    • 78650618910 scopus 로고    scopus 로고
    • Pro-inflammatory chemokine-chemokine receptor interactions within the Ewing sarcoma microenvironment determine CD8(+) T-lymphocyte infiltration and affect tumour progression
    • Berghuis D., Santos S.J., Baelde H.J., et al. Pro-inflammatory chemokine-chemokine receptor interactions within the Ewing sarcoma microenvironment determine CD8(+) T-lymphocyte infiltration and affect tumour progression. JPathol 2011, 223:347-357.
    • (2011) JPathol , vol.223 , pp. 347-357
    • Berghuis, D.1    Santos, S.J.2    Baelde, H.J.3
  • 40
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: harnessing the T cell response
    • Restifo N.P., Dudley M.E., Rosenberg S.A. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol 2012, 12:269-281.
    • (2012) Nat Rev Immunol , vol.12 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 41
    • 0036283538 scopus 로고    scopus 로고
    • Evidence that continued remission in patients treated for acute leukaemia is dependent upon autologous natural killer cells
    • Lowdell M.W., Craston R., Samuel D., et al. Evidence that continued remission in patients treated for acute leukaemia is dependent upon autologous natural killer cells. Br J Haematol 2002, 117:821-827.
    • (2002) Br J Haematol , vol.117 , pp. 821-827
    • Lowdell, M.W.1    Craston, R.2    Samuel, D.3
  • 42
    • 33845262483 scopus 로고    scopus 로고
    • Emergence of antitumor cytolytic T cells is associated with maintenance of hematologic remission in children with acute myeloid leukemia
    • Montagna D., Maccario R., Locatelli F., et al. Emergence of antitumor cytolytic T cells is associated with maintenance of hematologic remission in children with acute myeloid leukemia. Blood 2006, 108:3843-3850.
    • (2006) Blood , vol.108 , pp. 3843-3850
    • Montagna, D.1    Maccario, R.2    Locatelli, F.3
  • 43
    • 40949090196 scopus 로고    scopus 로고
    • Detection of WT1-specific T cells in paediatric acute lymphoblastic leukaemia patients in first remission
    • Barbaric D., Corthals S.L., Jastaniah W.A., et al. Detection of WT1-specific T cells in paediatric acute lymphoblastic leukaemia patients in first remission. Br J Haematol 2008, 141:271-273.
    • (2008) Br J Haematol , vol.141 , pp. 271-273
    • Barbaric, D.1    Corthals, S.L.2    Jastaniah, W.A.3
  • 44
    • 14844286852 scopus 로고    scopus 로고
    • Immunotherapy of cancer through targeting of minor histocompatibility antigens
    • Hambach L., Goulmy E. Immunotherapy of cancer through targeting of minor histocompatibility antigens. Curr Opin Immunol 2005, 17:202-210.
    • (2005) Curr Opin Immunol , vol.17 , pp. 202-210
    • Hambach, L.1    Goulmy, E.2
  • 45
    • 79952815781 scopus 로고    scopus 로고
    • Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia
    • Bleakley M., Riddell S.R. Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia. Immunol Cell Biol 2011, 89:396-407.
    • (2011) Immunol Cell Biol , vol.89 , pp. 396-407
    • Bleakley, M.1    Riddell, S.R.2
  • 46
    • 78650970845 scopus 로고    scopus 로고
    • Innate or adaptive immunity? The example of natural killer cells
    • Vivier E., Raulet D.H., Moretta A., et al. Innate or adaptive immunity? The example of natural killer cells. Science 2011, 331:44-49.
    • (2011) Science , vol.331 , pp. 44-49
    • Vivier, E.1    Raulet, D.H.2    Moretta, A.3
  • 47
    • 78751689960 scopus 로고    scopus 로고
    • Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation
    • Moretta L., Locatelli F., Pende D., et al. Killer Ig-like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation. Blood 2011, 117:764-771.
    • (2011) Blood , vol.117 , pp. 764-771
    • Moretta, L.1    Locatelli, F.2    Pende, D.3
  • 48
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri L., Capanni M., Urbani E., et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002, 295:2097-2100.
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 49
    • 63849104548 scopus 로고    scopus 로고
    • Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity
    • Pende D., Marcenaro S., Falco M., et al. Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity. Blood 2009, 113:3119-3129.
    • (2009) Blood , vol.113 , pp. 3119-3129
    • Pende, D.1    Marcenaro, S.2    Falco, M.3
  • 50
    • 34347396957 scopus 로고    scopus 로고
    • Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value
    • Ruggeri L., Mancusi A., Capanni M., et al. Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value. Blood 2007, 110:433-440.
    • (2007) Blood , vol.110 , pp. 433-440
    • Ruggeri, L.1    Mancusi, A.2    Capanni, M.3
  • 51
    • 77953644448 scopus 로고    scopus 로고
    • NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects
    • Olson J.A., Leveson-Gower D.B., Gill S., et al. NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects. Blood 2010, 115:4293-4301.
    • (2010) Blood , vol.115 , pp. 4293-4301
    • Olson, J.A.1    Leveson-Gower, D.B.2    Gill, S.3
  • 52
    • 0033575383 scopus 로고    scopus 로고
    • Prevention of graft versus host disease by inactivation of host antigen-presenting cells
    • Shlomchik W.D., Couzens M.S., Tang C.B., et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 1999, 285:412-415.
    • (1999) Science , vol.285 , pp. 412-415
    • Shlomchik, W.D.1    Couzens, M.S.2    Tang, C.B.3
  • 53
    • 84883723997 scopus 로고    scopus 로고
    • Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells
    • Locatelli F., Pende D., Mingari M.C., et al. Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells. Front Immunol 2013, 4:15.
    • (2013) Front Immunol , vol.4 , pp. 15
    • Locatelli, F.1    Pende, D.2    Mingari, M.C.3
  • 54
    • 77954862726 scopus 로고    scopus 로고
    • + progenitor cells and subsequent infusion after HLA-mismatched allogeneic hematopoietic cell transplantation: a feasibility study
    • + progenitor cells and subsequent infusion after HLA-mismatched allogeneic hematopoietic cell transplantation: a feasibility study. Bone Marrow Transplant 2010, 45:1038-1046.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1038-1046
    • Yoon, S.R.1    Lee, Y.S.2    Yang, S.H.3
  • 55
    • 84875230309 scopus 로고    scopus 로고
    • Pre-emptive immunotherapy with purified natural killer cells after haploidentical SCT: a prospective phase II study in two centers
    • Stern M., Passweg J.R., Meyer-Monard S., et al. Pre-emptive immunotherapy with purified natural killer cells after haploidentical SCT: a prospective phase II study in two centers. Bone Marrow Transplant 2013, 48:433-438.
    • (2013) Bone Marrow Transplant , vol.48 , pp. 433-438
    • Stern, M.1    Passweg, J.R.2    Meyer-Monard, S.3
  • 56
    • 79952109621 scopus 로고    scopus 로고
    • IL-2-activated haploidentical NK cells restore NKG2D-mediated NK-cell cytotoxicity in neuroblastoma patients by scavenging of plasma MICA
    • Kloess S., Huenecke S., Piechulek D., et al. IL-2-activated haploidentical NK cells restore NKG2D-mediated NK-cell cytotoxicity in neuroblastoma patients by scavenging of plasma MICA. Eur J Immunol 2010, 40:3255-3267.
    • (2010) Eur J Immunol , vol.40 , pp. 3255-3267
    • Kloess, S.1    Huenecke, S.2    Piechulek, D.3
  • 57
    • 20144388509 scopus 로고    scopus 로고
    • Successful adoptive transfer and invivo expansion of human haploidentical NK cells in patients with cancer
    • Miller J.S., Soignier Y., Panoskaltsis-Mortari A., et al. Successful adoptive transfer and invivo expansion of human haploidentical NK cells in patients with cancer. Blood 2005, 105:3051-3057.
    • (2005) Blood , vol.105 , pp. 3051-3057
    • Miller, J.S.1    Soignier, Y.2    Panoskaltsis-Mortari, A.3
  • 58
    • 77949898005 scopus 로고    scopus 로고
    • NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia
    • Rubnitz J.E., Inaba H., Ribeiro R.C., et al. NKAML: a pilot study to determine the safety and feasibility of haploidentical natural killer cell transplantation in childhood acute myeloid leukemia. JClin Oncol 2010, 28:955-959.
    • (2010) JClin Oncol , vol.28 , pp. 955-959
    • Rubnitz, J.E.1    Inaba, H.2    Ribeiro, R.C.3
  • 59
    • 80655128594 scopus 로고    scopus 로고
    • IL-2-stimulated, but not unstimulated, NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study
    • Brehm C., Huenecke S., Quaiser A., et al. IL-2-stimulated, but not unstimulated, NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study. PLoS ONE 2011, 6:e27351.
    • (2011) PLoS ONE , vol.6 , pp. e27351
    • Brehm, C.1    Huenecke, S.2    Quaiser, A.3
  • 60
    • 0025856106 scopus 로고
    • Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity
    • Schmidt-Wolf I.G., Negrin R.S., Kiem H.P., et al. Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. JExp Med 1991, 174:139-149.
    • (1991) JExp Med , vol.174 , pp. 139-149
    • Schmidt-Wolf, I.G.1    Negrin, R.S.2    Kiem, H.P.3
  • 61
    • 34548801834 scopus 로고    scopus 로고
    • Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study
    • Introna M., Borleri G., Conti E., et al. Repeated infusions of donor-derived cytokine-induced killer cells in patients relapsing after allogeneic stem cell transplantation: a phase I study. Haematologica 2007, 92:952-959.
    • (2007) Haematologica , vol.92 , pp. 952-959
    • Introna, M.1    Borleri, G.2    Conti, E.3
  • 62
    • 67650359909 scopus 로고    scopus 로고
    • Cytokine-induced killer cells as adoptive immunotherapy strategy to augment graft versus tumor after hematopoietic cell transplantation
    • Sangiolo D., Mesiano G., Carnevale-Schianca F., et al. Cytokine-induced killer cells as adoptive immunotherapy strategy to augment graft versus tumor after hematopoietic cell transplantation. Expert Opin Biol Ther 2009, 9:831-840.
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 831-840
    • Sangiolo, D.1    Mesiano, G.2    Carnevale-Schianca, F.3
  • 63
    • 77956823289 scopus 로고    scopus 로고
    • Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells: implications for adoptive immunotherapy after allogeneic stem cell transplantation
    • Kuci S., Rettinger E., Voss B., et al. Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells: implications for adoptive immunotherapy after allogeneic stem cell transplantation. Haematologica 2010, 95:1579-1586.
    • (2010) Haematologica , vol.95 , pp. 1579-1586
    • Kuci, S.1    Rettinger, E.2    Voss, B.3
  • 64
    • 59449109417 scopus 로고    scopus 로고
    • Characterization of the recognition and functional heterogeneity exhibited by cytokine-induced killer cell subsets against acute myeloid leukaemia target cell
    • Linn Y.C., Lau S.K., Liu B.H., et al. Characterization of the recognition and functional heterogeneity exhibited by cytokine-induced killer cell subsets against acute myeloid leukaemia target cell. Immunology 2009, 126:423-435.
    • (2009) Immunology , vol.126 , pp. 423-435
    • Linn, Y.C.1    Lau, S.K.2    Liu, B.H.3
  • 65
    • 45749097431 scopus 로고    scopus 로고
    • Alloreactivity and anti-tumor activity segregate within two distinct subsets of cytokine-induced killer (CIK) cells: implications for their infusion across major HLA barriers
    • Sangiolo D., Martinuzzi E., Todorovic M., et al. Alloreactivity and anti-tumor activity segregate within two distinct subsets of cytokine-induced killer (CIK) cells: implications for their infusion across major HLA barriers. Int Immunol 2008, 20:841-848.
    • (2008) Int Immunol , vol.20 , pp. 841-848
    • Sangiolo, D.1    Martinuzzi, E.2    Todorovic, M.3
  • 66
    • 80053210017 scopus 로고    scopus 로고
    • Adoptive immunotherapy with cytokine-induced killer cells for patients with relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation
    • Laport G.G., Sheehan K., Baker J., et al. Adoptive immunotherapy with cytokine-induced killer cells for patients with relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2011, 17:1679-1687.
    • (2011) Biol Blood Marrow Transplant , vol.17 , pp. 1679-1687
    • Laport, G.G.1    Sheehan, K.2    Baker, J.3
  • 67
    • 84863722188 scopus 로고    scopus 로고
    • The anti-tumour activity of allogeneic cytokine-induced killer cells in patients who relapse after allogeneic transplant for haematological malignancies
    • Linn Y.C., Niam M., Chu S., et al. The anti-tumour activity of allogeneic cytokine-induced killer cells in patients who relapse after allogeneic transplant for haematological malignancies. Bone Marrow Transplant 2012, 47:957-966.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 957-966
    • Linn, Y.C.1    Niam, M.2    Chu, S.3
  • 68
    • 84881376076 scopus 로고    scopus 로고
    • Feasibility of IL-15-activated cytokine-induced killer cell infusions after haploidentical stem cell transplantation
    • Rettinger E., Bonig H., Wehner S., et al. Feasibility of IL-15-activated cytokine-induced killer cell infusions after haploidentical stem cell transplantation. Bone Marrow Transplant 2013, 48:1141-1143.
    • (2013) Bone Marrow Transplant , vol.48 , pp. 1141-1143
    • Rettinger, E.1    Bonig, H.2    Wehner, S.3
  • 69
    • 56649095905 scopus 로고    scopus 로고
    • Tregulatory cells in autoimmune diabetes: past challenges, future prospects
    • Bluestone J.A., Tang Q., Sedwick C.E. Tregulatory cells in autoimmune diabetes: past challenges, future prospects. JClin Immunol 2008, 28:677-684.
    • (2008) JClin Immunol , vol.28 , pp. 677-684
    • Bluestone, J.A.1    Tang, Q.2    Sedwick, C.E.3
  • 70
    • 2942642383 scopus 로고    scopus 로고
    • Invitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
    • Tang Q., Henriksen K.J., Bi M., et al. Invitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. JExp Med 2004, 199:1455-1465.
    • (2004) JExp Med , vol.199 , pp. 1455-1465
    • Tang, Q.1    Henriksen, K.J.2    Bi, M.3
  • 71
    • 9444280125 scopus 로고    scopus 로고
    • + T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
    • + T-regulatory cells are potent inhibitors of GVHD and BM graft rejection. Blood 2004, 104:3804-3812.
    • (2004) Blood , vol.104 , pp. 3804-3812
    • Taylor, P.A.1    Panoskaltsis-Mortari, A.2    Swedin, J.M.3
  • 72
    • 0141461418 scopus 로고    scopus 로고
    • + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation
    • + regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation. Nat Med 2003, 9:1144-1150.
    • (2003) Nat Med , vol.9 , pp. 1144-1150
    • Edinger, M.1    Hoffmann, P.2    Ermann, J.3
  • 73
    • 0035806323 scopus 로고    scopus 로고
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded invitro without loss of function
    • + T regulatory cells suppress naive and memory T cell proliferation and can be expanded invitro without loss of function. JExp Med 2001, 193:1295-1302.
    • (2001) JExp Med , vol.193 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.G.3
  • 74
    • 0035806290 scopus 로고    scopus 로고
    • + T cells with regulatory properties isolated from peripheral blood
    • + T cells with regulatory properties isolated from peripheral blood. JExp Med 2001, 193:1285-1294.
    • (2001) JExp Med , vol.193 , pp. 1285-1294
    • Jonuleit, H.1    Schmitt, E.2    Stassen, M.3
  • 75
    • 79953809817 scopus 로고    scopus 로고
    • Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation
    • Di Ianni M., Falzetti F., Carotti A., et al. Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation. Blood 2011, 117:3921-3928.
    • (2011) Blood , vol.117 , pp. 3921-3928
    • Di Ianni, M.1    Falzetti, F.2    Carotti, A.3
  • 76
    • 78751696183 scopus 로고    scopus 로고
    • Infusion of exvivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics
    • Brunstein C.G., Miller J.S., Cao Q., et al. Infusion of exvivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics. Blood 2011, 117:1061-1070.
    • (2011) Blood , vol.117 , pp. 1061-1070
    • Brunstein, C.G.1    Miller, J.S.2    Cao, Q.3
  • 80
    • 84877669593 scopus 로고    scopus 로고
    • The basic principles of chimeric antigen receptor design
    • Sadelain M., Brentjens R., Riviere I. The basic principles of chimeric antigen receptor design. Cancer Discov 2013, 3:388-398.
    • (2013) Cancer Discov , vol.3 , pp. 388-398
    • Sadelain, M.1    Brentjens, R.2    Riviere, I.3
  • 81
    • 84879384673 scopus 로고    scopus 로고
    • Novel cellular therapies for leukemia: CAR-modified T cells targeted to the CD19 antigen
    • Brentjens R.J., Curran K.J. Novel cellular therapies for leukemia: CAR-modified T cells targeted to the CD19 antigen. Hematology Am Soc Hematol Educ Program 2012, 2012:143-151.
    • (2012) Hematology Am Soc Hematol Educ Program , vol.2012 , pp. 143-151
    • Brentjens, R.J.1    Curran, K.J.2
  • 82
    • 77956535599 scopus 로고    scopus 로고
    • Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
    • Jena B., Dotti G., Cooper L.J. Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor. Blood 2010, 116:1035-1044.
    • (2010) Blood , vol.116 , pp. 1035-1044
    • Jena, B.1    Dotti, G.2    Cooper, L.J.3
  • 83
    • 84862775412 scopus 로고    scopus 로고
    • Targeted immunotherapy of cancer with CAR T cells: achievements and challenges
    • Lipowska-Bhalla G., Gilham D.E., Hawkins R.E., et al. Targeted immunotherapy of cancer with CAR T cells: achievements and challenges. Cancer Immunol Immunother 2012, 61:953-962.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 953-962
    • Lipowska-Bhalla, G.1    Gilham, D.E.2    Hawkins, R.E.3
  • 84
    • 33947265424 scopus 로고    scopus 로고
    • Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma
    • Park J.R., Digiusto D.L., Slovak M., et al. Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma. Mol Ther 2007, 15:825-833.
    • (2007) Mol Ther , vol.15 , pp. 825-833
    • Park, J.R.1    Digiusto, D.L.2    Slovak, M.3
  • 85
    • 77954590000 scopus 로고    scopus 로고
    • Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
    • Hoyos V., Savoldo B., Quintarelli C., et al. Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety. Leukemia 2010, 24:1160-1170.
    • (2010) Leukemia , vol.24 , pp. 1160-1170
    • Hoyos, V.1    Savoldo, B.2    Quintarelli, C.3
  • 86
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
    • Savoldo B., Ramos C.A., Liu E., et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. JClin Invest 2011, 121:1822-1826.
    • (2011) JClin Invest , vol.121 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3
  • 87
    • 55549145071 scopus 로고    scopus 로고
    • Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
    • Pule M.A., Savoldo B., Myers G.D., et al. Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med 2008, 14:1264-1270.
    • (2008) Nat Med , vol.14 , pp. 1264-1270
    • Pule, M.A.1    Savoldo, B.2    Myers, G.D.3
  • 88
    • 0037085804 scopus 로고    scopus 로고
    • Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy
    • Rossig C., Bollard C.M., Nuchtern J.G., et al. Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy. Blood 2002, 99:2009-2016.
    • (2002) Blood , vol.99 , pp. 2009-2016
    • Rossig, C.1    Bollard, C.M.2    Nuchtern, J.G.3
  • 89
    • 84897960533 scopus 로고    scopus 로고
    • Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy
    • Barrett D.M., Singh N., Liu X., et al. Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy. Cytotherapy 2014, 16:619-630.
    • (2014) Cytotherapy , vol.16 , pp. 619-630
    • Barrett, D.M.1    Singh, N.2    Liu, X.3
  • 90
    • 84876005284 scopus 로고    scopus 로고
    • CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
    • 177ra38
    • Brentjens R.J., Davila M.L., Riviere I., et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med 2013, 5:177ra38.
    • (2013) Sci Transl Med , vol.5
    • Brentjens, R.J.1    Davila, M.L.2    Riviere, I.3
  • 91
    • 84876325876 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
    • Grupp S.A., Kalos M., Barrett D., et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. NEngl J Med 2013, 368:1509-1518.
    • (2013) NEngl J Med , vol.368 , pp. 1509-1518
    • Grupp, S.A.1    Kalos, M.2    Barrett, D.3
  • 92
    • 84875138464 scopus 로고    scopus 로고
    • Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy
    • Hackett P.B., Largaespada D.A., Switzer K.C., et al. Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy. Transl Res 2013, 161:265-283.
    • (2013) Transl Res , vol.161 , pp. 265-283
    • Hackett, P.B.1    Largaespada, D.A.2    Switzer, K.C.3
  • 93
    • 84887821770 scopus 로고    scopus 로고
    • Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study
    • Cruz C.R., Micklethwaite K.P., Savoldo B., et al. Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood 2013, 122:2965-2973.
    • (2013) Blood , vol.122 , pp. 2965-2973
    • Cruz, C.R.1    Micklethwaite, K.P.2    Savoldo, B.3
  • 94
    • 77950501752 scopus 로고    scopus 로고
    • Safer CARS
    • Heslop H.E. Safer CARS. Mol Ther 2010, 18:661-662.
    • (2010) Mol Ther , vol.18 , pp. 661-662
    • Heslop, H.E.1
  • 95
    • 33646440024 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience
    • Lamers C.H., Sleijfer S., Vulto A.G., et al. Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. JClin Oncol 2006, 24:e20-e22.
    • (2006) JClin Oncol , vol.24 , pp. e20-e22
    • Lamers, C.H.1    Sleijfer, S.2    Vulto, A.G.3
  • 96
    • 84880730689 scopus 로고    scopus 로고
    • Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
    • Linette G.P., Stadtmauer E.A., Maus M.V., et al. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood 2013, 122:863-871.
    • (2013) Blood , vol.122 , pp. 863-871
    • Linette, G.P.1    Stadtmauer, E.A.2    Maus, M.V.3
  • 97
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • Morgan R.A., Yang J.C., Kitano M., et al. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 2010, 18:843-851.
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.A.1    Yang, J.C.2    Kitano, M.3
  • 98
    • 84897548232 scopus 로고    scopus 로고
    • Tcells engineered with a chimeric antigen receptor (CAR) targeting CD19 (CTL019) produce significant invivo proliferation, complete responses and long-term persistence without GVHD in children and adults with relapsed, refractory ALL
    • [abstract]
    • Grupp S.A., Frey N.V., Aplenc R., et al. Tcells engineered with a chimeric antigen receptor (CAR) targeting CD19 (CTL019) produce significant invivo proliferation, complete responses and long-term persistence without GVHD in children and adults with relapsed, refractory ALL. Blood 2013, 122:67. [abstract].
    • (2013) Blood , vol.122 , pp. 67
    • Grupp, S.A.1    Frey, N.V.2    Aplenc, R.3
  • 99
    • 84882782587 scopus 로고    scopus 로고
    • Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy
    • Teachey D.T., Rheingold S.R., Maude S.L., et al. Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy. Blood 2013, 121:5154-5157.
    • (2013) Blood , vol.121 , pp. 5154-5157
    • Teachey, D.T.1    Rheingold, S.R.2    Maude, S.L.3
  • 100
    • 84897565985 scopus 로고    scopus 로고
    • Anti-CD19 chimeric antigen receptor (CAR) T cells produce complete responses with acceptable toxicity but without chronic B-cell aplasia in children with relapsed or refractory acute lymphoblastic leukemia (ALL) even after allogeneic hematopoietic stem cell transplantation (HSCT)
    • [abstract]
    • Lee D.W., Shah N.N., Stetler-Stevenson M., et al. Anti-CD19 chimeric antigen receptor (CAR) T cells produce complete responses with acceptable toxicity but without chronic B-cell aplasia in children with relapsed or refractory acute lymphoblastic leukemia (ALL) even after allogeneic hematopoietic stem cell transplantation (HSCT). Blood 2013, 122:68. [abstract].
    • (2013) Blood , vol.122 , pp. 68
    • Lee, D.W.1    Shah, N.N.2    Stetler-Stevenson, M.3
  • 101
    • 70149114880 scopus 로고    scopus 로고
    • Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
    • Johnson L.A., Morgan R.A., Dudley M.E., et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009, 114:535-546.
    • (2009) Blood , vol.114 , pp. 535-546
    • Johnson, L.A.1    Morgan, R.A.2    Dudley, M.E.3
  • 102
    • 33749624177 scopus 로고    scopus 로고
    • Cancer regression in patients after transfer of genetically engineered lymphocytes
    • Morgan R.A., Dudley M.E., Wunderlich J.R., et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006, 314:126-129.
    • (2006) Science , vol.314 , pp. 126-129
    • Morgan, R.A.1    Dudley, M.E.2    Wunderlich, J.R.3
  • 103
    • 22044456688 scopus 로고    scopus 로고
    • Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
    • Imai C., Iwamoto S., Campana D. Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells. Blood 2005, 106:376-383.
    • (2005) Blood , vol.106 , pp. 376-383
    • Imai, C.1    Iwamoto, S.2    Campana, D.3
  • 104
    • 37349039692 scopus 로고    scopus 로고
    • Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK resistance of lymphoma and leukemia cells
    • Muller T., Uherek C., Maki G., et al. Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK resistance of lymphoma and leukemia cells. Cancer Immunol Immunother 2008, 57:411-423.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 411-423
    • Muller, T.1    Uherek, C.2    Maki, G.3
  • 105
    • 84856267795 scopus 로고    scopus 로고
    • NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
    • Esser R., Muller T., Stefes D., et al. NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin. JCell Mol Med 2012, 16:569-581.
    • (2012) JCell Mol Med , vol.16 , pp. 569-581
    • Esser, R.1    Muller, T.2    Stefes, D.3
  • 106
    • 68049142423 scopus 로고    scopus 로고
    • 2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells
    • Altvater B., Landmeier S., Pscherer S., et al. 2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells. Clin Cancer Res 2009, 15:4857-4866.
    • (2009) Clin Cancer Res , vol.15 , pp. 4857-4866
    • Altvater, B.1    Landmeier, S.2    Pscherer, S.3
  • 107
    • 0037103311 scopus 로고    scopus 로고
    • Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction
    • Uherek C., Tonn T., Uherek B., et al. Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction. Blood 2002, 100:1265-1273.
    • (2002) Blood , vol.100 , pp. 1265-1273
    • Uherek, C.1    Tonn, T.2    Uherek, B.3
  • 108
    • 84866541747 scopus 로고    scopus 로고
    • Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor
    • Sahm C., Schonfeld K., Wels W.S. Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor. Cancer Immunol Immunother 2012, 61:1451-1461.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 1451-1461
    • Sahm, C.1    Schonfeld, K.2    Wels, W.S.3
  • 109
    • 84855944650 scopus 로고    scopus 로고
    • Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor
    • Tassev D.V., Cheng M., Cheung N.K. Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor. Cancer Gene Ther 2012, 19:84-100.
    • (2012) Cancer Gene Ther , vol.19 , pp. 84-100
    • Tassev, D.V.1    Cheng, M.2    Cheung, N.K.3
  • 110
    • 84875469893 scopus 로고    scopus 로고
    • Achimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells
    • Chang Y.H., Connolly J., Shimasaki N., et al. Achimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells. Cancer Res 2013, 73:1777-1786.
    • (2013) Cancer Res , vol.73 , pp. 1777-1786
    • Chang, Y.H.1    Connolly, J.2    Shimasaki, N.3
  • 111
    • 65949111530 scopus 로고    scopus 로고
    • Expansion of highly cytotoxic human natural killer cells for cancer cell therapy
    • Fujisaki H., Kakuda H., Shimasaki N., et al. Expansion of highly cytotoxic human natural killer cells for cancer cell therapy. Cancer Res 2009, 69:4010-4017.
    • (2009) Cancer Res , vol.69 , pp. 4010-4017
    • Fujisaki, H.1    Kakuda, H.2    Shimasaki, N.3
  • 112
    • 3042551216 scopus 로고    scopus 로고
    • Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia
    • Imai C., Mihara K., Andreansky M., et al. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia. Leukemia 2004, 18:676-684.
    • (2004) Leukemia , vol.18 , pp. 676-684
    • Imai, C.1    Mihara, K.2    Andreansky, M.3
  • 113
    • 84905714921 scopus 로고    scopus 로고
    • Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells invivo
    • Pizzitola I., Anjos-Afonso F., Rouault-Pierre K., et al. Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells invivo. Leukemia 2014, doi:10.1038/leu.2014.62.
    • (2014) Leukemia
    • Pizzitola, I.1    Anjos-Afonso, F.2    Rouault-Pierre, K.3
  • 114
    • 77349093500 scopus 로고    scopus 로고
    • Harnessing human dendritic cell subsets for medicine
    • Ueno H., Schmitt N., Klechevsky E., et al. Harnessing human dendritic cell subsets for medicine. Immunol Rev 2010, 234:199-212.
    • (2010) Immunol Rev , vol.234 , pp. 199-212
    • Ueno, H.1    Schmitt, N.2    Klechevsky, E.3
  • 115
    • 30844450344 scopus 로고    scopus 로고
    • Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation
    • Bendandi M., Rodriguez-Calvillo M., Inoges S., et al. Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation. Leuk Lymphoma 2006, 47:29-37.
    • (2006) Leuk Lymphoma , vol.47 , pp. 29-37
    • Bendandi, M.1    Rodriguez-Calvillo, M.2    Inoges, S.3
  • 116
    • 0034904675 scopus 로고    scopus 로고
    • Treatment of post-transplanted, relapsed patients with hematological malignancies by infusion of HLA-matched, allogeneic-dendritic cells (DCs) pulsed with irradiated tumor cells and primed T cells
    • Fujii S., Shimizu K., Fujimoto K., et al. Treatment of post-transplanted, relapsed patients with hematological malignancies by infusion of HLA-matched, allogeneic-dendritic cells (DCs) pulsed with irradiated tumor cells and primed T cells. Leuk Lymphoma 2001, 42:357-369.
    • (2001) Leuk Lymphoma , vol.42 , pp. 357-369
    • Fujii, S.1    Shimizu, K.2    Fujimoto, K.3
  • 117
    • 41449110340 scopus 로고    scopus 로고
    • Potential of dendritic-cell immunotherapy for relapse after allogeneic hematopoietic stem cell transplantation, shown by WT1 peptide- and keyhole-limpet-hemocyanin-pulsed, donor-derived dendritic-cell vaccine for acute myeloid leukemia
    • Kitawaki T., Kadowaki N., Kondo T., et al. Potential of dendritic-cell immunotherapy for relapse after allogeneic hematopoietic stem cell transplantation, shown by WT1 peptide- and keyhole-limpet-hemocyanin-pulsed, donor-derived dendritic-cell vaccine for acute myeloid leukemia. Am J Hematol 2008, 83:315-317.
    • (2008) Am J Hematol , vol.83 , pp. 315-317
    • Kitawaki, T.1    Kadowaki, N.2    Kondo, T.3
  • 118
    • 75749084756 scopus 로고    scopus 로고
    • Partial T cell-depleted allogeneic stem cell transplantation following reduced-intensity conditioning creates a platform for immunotherapy with donor lymphocyte infusion and recipient dendritic cell vaccination in multiple myeloma
    • Levenga H., Schaap N., Maas F., et al. Partial T cell-depleted allogeneic stem cell transplantation following reduced-intensity conditioning creates a platform for immunotherapy with donor lymphocyte infusion and recipient dendritic cell vaccination in multiple myeloma. Biol Blood Marrow Transplant 2010, 16:320-332.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 320-332
    • Levenga, H.1    Schaap, N.2    Maas, F.3
  • 119
    • 34548094872 scopus 로고    scopus 로고
    • Dendritic cell vaccination in allogeneic stem cell recipients: induction of human cytomegalovirus (HCMV)-specific cytotoxic T lymphocyte responses even in patients receiving a transplant from an HCMV-seronegative donor
    • Grigoleit G.U., Kapp M., Hebart H., et al. Dendritic cell vaccination in allogeneic stem cell recipients: induction of human cytomegalovirus (HCMV)-specific cytotoxic T lymphocyte responses even in patients receiving a transplant from an HCMV-seronegative donor. JInfect Dis 2007, 196:699-704.
    • (2007) JInfect Dis , vol.196 , pp. 699-704
    • Grigoleit, G.U.1    Kapp, M.2    Hebart, H.3
  • 120
    • 0035576891 scopus 로고    scopus 로고
    • Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression
    • Geiger J.D., Hutchinson R.J., Hohenkirk L.F., et al. Vaccination of pediatric solid tumor patients with tumor lysate-pulsed dendritic cells can expand specific T cells and mediate tumor regression. Cancer Res 2001, 61:8513-8519.
    • (2001) Cancer Res , vol.61 , pp. 8513-8519
    • Geiger, J.D.1    Hutchinson, R.J.2    Hohenkirk, L.F.3
  • 121
    • 84901987199 scopus 로고    scopus 로고
    • Dendritic cell vaccination in pediatric gliomas: lessons learnt and future perspectives
    • Eyrich M., Rachor J., Schreiber S.C., et al. Dendritic cell vaccination in pediatric gliomas: lessons learnt and future perspectives. Front Pediatr 2013, 1:12.
    • (2013) Front Pediatr , vol.1 , pp. 12
    • Eyrich, M.1    Rachor, J.2    Schreiber, S.C.3
  • 122
    • 0014261390 scopus 로고
    • Heterotopic of bone marrow: analysis of precursor cells for osteogenic and hematopoietic tissues
    • Friedenstein A.J., Petrakova K.V., Kurolesova A.I., et al. Heterotopic of bone marrow: analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 1968, 6:230-247.
    • (1968) Transplantation , vol.6 , pp. 230-247
    • Friedenstein, A.J.1    Petrakova, K.V.2    Kurolesova, A.I.3
  • 123
    • 36348977575 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells
    • Nauta A.J., Fibbe W.E. Immunomodulatory properties of mesenchymal stromal cells. Blood 2007, 110:3499-3506.
    • (2007) Blood , vol.110 , pp. 3499-3506
    • Nauta, A.J.1    Fibbe, W.E.2
  • 124
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K., Rasmusson I., Sundberg B., et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004, 363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 125
    • 43049103438 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
    • Le Blanc K., Frassoni F., Ball L., et al. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet 2008, 371:1579-1586.
    • (2008) Lancet , vol.371 , pp. 1579-1586
    • Le Blanc, K.1    Frassoni, F.2    Ball, L.3
  • 126
    • 77955509074 scopus 로고    scopus 로고
    • Platelet-lysate-expanded mesenchymal stromal cells as a salvage therapy for severe resistant graft-versus-host disease in a pediatric population
    • Lucchini G., Introna M., Dander E., et al. Platelet-lysate-expanded mesenchymal stromal cells as a salvage therapy for severe resistant graft-versus-host disease in a pediatric population. Biol Blood Marrow Transplant 2010, 16:1293-1301.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1293-1301
    • Lucchini, G.1    Introna, M.2    Dander, E.3
  • 127
    • 84886404127 scopus 로고    scopus 로고
    • Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease
    • Ball L.M., Bernardo M.E., Roelofs H., et al. Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid-refractory, grade III-IV acute graft-versus-host disease. Br J Haematol 2013, 163:501-509.
    • (2013) Br J Haematol , vol.163 , pp. 501-509
    • Ball, L.M.1    Bernardo, M.E.2    Roelofs, H.3
  • 128
    • 84896710813 scopus 로고    scopus 로고
    • Treatment of graft-versus-host disease with mesenchymal stromal cells: a phase i study on 40 adult and pediatric patients
    • Introna M., Lucchini G., Dander E., et al. Treatment of graft-versus-host disease with mesenchymal stromal cells: a phase i study on 40 adult and pediatric patients. Biol Blood Marrow Transplant 2014, 20:375-381.
    • (2014) Biol Blood Marrow Transplant , vol.20 , pp. 375-381
    • Introna, M.1    Lucchini, G.2    Dander, E.3
  • 129
    • 79952624644 scopus 로고    scopus 로고
    • Efficacy and safety of exvivo cultured adult human mesenchymal stem cells (Prochymal) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study
    • Prasad V.K., Lucas K.G., Kleiner G.I., et al. Efficacy and safety of exvivo cultured adult human mesenchymal stem cells (Prochymal) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study. Biol Blood Marrow Transplant 2011, 17:534-541.
    • (2011) Biol Blood Marrow Transplant , vol.17 , pp. 534-541
    • Prasad, V.K.1    Lucas, K.G.2    Kleiner, G.I.3
  • 130
    • 70449368623 scopus 로고    scopus 로고
    • Genzyme backs Osiris, despite Prochymal flop
    • Allison M. Genzyme backs Osiris, despite Prochymal flop. Nat Biotechnol 2009, 27:966-967.
    • (2009) Nat Biotechnol , vol.27 , pp. 966-967
    • Allison, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.