Effective treatment of refractory CMV reactivation after allogeneic stem cell transplantation with in vitro-generated CMV pp65-specific CD8+ T-cell lines

Journal of Immunotherapy

Volumn 35, Issue 8, 2012, Pages 621-628

  Meij, Pauline ^a   Jedema, Inge ^a   Zandvliet, Maarten L ^a   Van Der Heiden, Pim L J ^a   Van De Meent, Marian ^a   Van Egmond, H M Esther ^a   Van Liempt, Ellis ^a   Hoogstraten, Conny ^a   Kruithof, Simone ^a   Veld, Sabrina ^a   Marijt, Erik W A ^a   Von Dem Borne, Peter A ^a   Lankester, Arjan C ^a   Halkes, Constantijn J M ^a   Falkenburg, J H Frederik ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

adoptive immunotherapy; allogeneic stem cell transplantation; CMV; CMV pp65; T cell

Indexed keywords

ANTIVIRUS AGENT; CD4 ANTIGEN; CD8 ANTIGEN; CYTOMEGALOVIRUS ANTIGEN PP65; GAMMA INTERFERON; HLA A ANTIGEN; HLA B ANTIGEN; INTERLEUKIN 2; VIRUS DNA;

ADOPTIVE TRANSFER; ADULT; ALLOGENEIC STEM CELL TRANSPLANTATION; ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOLYSIS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; FEASIBILITY STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERFERON PRODUCTION; MEDICAL DEVICE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SAFETY; TARGET CELL; TREATMENT OUTCOME; VIRUS LOAD; VIRUS REACTIVATION;

CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CYTOTOXICITY, IMMUNOLOGIC; HERPES SIMPLEX; HLA-A2 ANTIGEN; HLA-B7 ANTIGEN; HUMANS; IMMUNOTHERAPY, ADOPTIVE; INTERFERON-GAMMA; INTERLEUKIN-2; PEPTIDE FRAGMENTS; PHOSPHOPROTEINS; POSTOPERATIVE COMPLICATIONS; PROTEIN BINDING; SIMPLEXVIRUS; STEM CELL TRANSPLANTATION; TRANSPLANTATION, HOMOLOGOUS; VIRAL LOAD; VIRAL MATRIX PROTEINS; VIRUS ACTIVATION;

EID: 84866702645     PISSN: 15249557     EISSN: 15374513     Source Type: Journal    
DOI: 10.1097/CJI.0b013e31826e35f6     Document Type: Article

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