메뉴 건너뛰기




Volumn 65, Issue 2, 2015, Pages 101-109

G protein-coupled receptor signaling in cardiac nuclear membranes

Author keywords

cardiomyocyte; GPCR; heart; intracrine signaling; nucleus; transcriptome

Indexed keywords

ANGIOTENSIN II; BETA ADRENERGIC RECEPTOR; ENDOTHELIN; G PROTEIN COUPLED RECEPTOR; ADRENERGIC RECEPTOR; ANGIOTENSIN RECEPTOR; CARDIOVASCULAR AGENT; ENDOTHELIN RECEPTOR; LIGAND;

EID: 84922732076     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0000000000000196     Document Type: Review
Times cited : (28)

References (141)
  • 1
    • 84858228729 scopus 로고    scopus 로고
    • G protein-coupled receptor signaling in the cardiac nuclear membrane: Evidence and possible roles in physiological and pathophysiological function
    • Tadevosyan A, Vaniotis G, Allen BG, et al. G protein-coupled receptor signaling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function. J Physiol. 2012;590 (pt 6):1313-1330.
    • (2012) J Physiol. , vol.590 , pp. 1313-1330
    • Tadevosyan, A.1    Vaniotis, G.2    Allen, B.G.3
  • 2
    • 0021735533 scopus 로고
    • Angiotensin II receptors in chromatin
    • Re RN, Vizard DL, Brown J, et al. Angiotensin II receptors in chromatin. J Hypertens. 1984;2:S271-S273.
    • (1984) J Hypertens. , vol.2 , pp. S271-S273
    • Re, R.N.1    Vizard, D.L.2    Brown, J.3
  • 3
    • 0026703607 scopus 로고
    • Angiotensin-II binding sites on hepatocyte nuclei
    • Booz GW, Conrad KM, Hess AL, et al. Angiotensin-II binding sites on hepatocyte nuclei. Endocrinology. 1992;130:3641-3649.
    • (1992) Endocrinology. , vol.130 , pp. 3641-3649
    • Booz, G.W.1    Conrad, K.M.2    Hess, A.L.3
  • 4
    • 77954619980 scopus 로고    scopus 로고
    • Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression
    • Tadevosyan A, Maguy A, Villeneuve LR, et al. Nuclear-delimited angiotensin receptor-mediated signaling regulates cardiomyocyte gene expression. J Biol Chem. 2010;295:22338-22349.
    • (2010) J Biol Chem. , vol.295 , pp. 22338-22349
    • Tadevosyan, A.1    Maguy, A.2    Villeneuve, L.R.3
  • 5
    • 44449119495 scopus 로고    scopus 로고
    • Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation
    • Savard M, Barbaz D, Belanger S, et al. Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation. J Cell Physiol. 2008;216:234-244.
    • (2008) J Cell Physiol. , vol.216 , pp. 234-244
    • Savard, M.1    Barbaz, D.2    Belanger, S.3
  • 6
    • 55449108079 scopus 로고    scopus 로고
    • Nuclear a1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes
    • Wright CD, Chen Q, Baye NL, et al. Nuclear a1-adrenergic receptors signal activated ERK localization to caveolae in adult cardiac myocytes. Circ Res. 2008;103:992-1000.
    • (2008) Circ Res. , vol.103 , pp. 992-1000
    • Wright, C.D.1    Chen, Q.2    Baye, N.L.3
  • 7
    • 84855574457 scopus 로고    scopus 로고
    • Nuclear localization drives a1-adrenergic receptor oligomerization and signaling in cardiac myocytes
    • Wright CD, Wu SC, Dahl EF, et al. Nuclear localization drives a1-adrenergic receptor oligomerization and signaling in cardiac myocytes. Cell Signal. 2012;24:794-802.
    • (2012) Cell Signal. , vol.24 , pp. 794-802
    • Wright, C.D.1    Wu, S.C.2    Dahl, E.F.3
  • 8
    • 33744909351 scopus 로고    scopus 로고
    • Functional b-adrenergic receptor signaling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes
    • Boivin B, Lavoie C, Vaniotis G, et al. Functional b-adrenergic receptor signaling on nuclear membranes in adult rat and mouse ventricular cardiomyocytes. Cardiovasc Res. 2006;71:69-78.
    • (2006) Cardiovasc Res. , vol.71 , pp. 69-78
    • Boivin, B.1    Lavoie, C.2    Vaniotis, G.3
  • 9
    • 77957774460 scopus 로고    scopus 로고
    • Nuclear b-adrenergic receptors modulate gene expression in adult rat heart
    • Vaniotis G, Del Duca D, Trieu P, et al. Nuclear b-adrenergic receptors modulate gene expression in adult rat heart. Cell Signal. 2011;23:89-98.
    • (2011) Cell Signal. , vol.23 , pp. 89-98
    • Vaniotis, G.1    Del Duca, D.2    Trieu, P.3
  • 10
    • 0041706091 scopus 로고    scopus 로고
    • Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes
    • Boivin B, Chevalier D, Villeneuve LR, et al. Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes. J Biol Chem. 2003;278:29153-29163.
    • (2003) J Biol Chem. , vol.278 , pp. 29153-29163
    • Boivin, B.1    Chevalier, D.2    Villeneuve, L.R.3
  • 11
    • 0022472685 scopus 로고
    • Subcellular distribution of the external and interanl domains of the EGF receptor in A-431 cells
    • Carpentier IL, Rees AR, Gregoriou M, et al. Subcellular distribution of the external and interanl domains of the EGF receptor in A-431 cells. Exp Cell Res. 1986;166:312-326.
    • (1986) Exp Cell Res. , vol.166 , pp. 312-326
    • Carpentier, I.L.1    Rees, A.R.2    Gregoriou, M.3
  • 12
    • 0034654554 scopus 로고    scopus 로고
    • Nuclear expression of the c-erbB-4/HER-4 growth factor receptor in invasive breast cancer
    • Srinivasan R, Gillett CE, Barnes DM, et al. Nuclear expression of the c-erbB-4/HER-4 growth factor receptor in invasive breast cancer. Cancer Res. 2000;60:1483-1487.
    • (2000) Cancer Res. , vol.60 , pp. 1483-1487
    • Srinivasan, R.1    Gillett, C.E.2    Barnes, D.M.3
  • 13
    • 0029785143 scopus 로고    scopus 로고
    • Nuclear accumulation of fibroblast growth factor receptors is regulated by multiple signals in adrenal medullary cells
    • Stachowiak MK, Maher PA, Joy A, et al. Nuclear accumulation of fibroblast growth factor receptors is regulated by multiple signals in adrenal medullary cells. Mol Biol Cell. 1996;7:1299-1317.
    • (1996) Mol Biol Cell. , vol.7 , pp. 1299-1317
    • Stachowiak, M.K.1    Maher, P.A.2    Joy, A.3
  • 14
    • 0018250147 scopus 로고
    • Insulin binding sites on rat liver nuclear membranes: Biochemical and immunological studies
    • Horvat A. Insulin binding sites on rat liver nuclear membranes: biochemical and immunological studies. J Cell Physiol. 1978;97:37-47.
    • (1978) J Cell Physiol. , vol.97 , pp. 37-47
    • Horvat, A.1
  • 15
    • 0018090531 scopus 로고
    • The nuclear envelope. the major site of insulin binding in rat liver nuclei
    • Vigneri R, Goldfine ID, Wong KY, et al. The nuclear envelope. The major site of insulin binding in rat liver nuclei. J Biol Chem. 1978;253: 2098-2103.
    • (1978) J Biol Chem. , vol.253 , pp. 2098-2103
    • Vigneri, R.1    Goldfine, I.D.2    Wong, K.Y.3
  • 16
    • 0021840472 scopus 로고
    • Murine interferonbeta receptor-mediated endocytosis and nuclear membrane binding
    • Kushnaryov VM, MacDonald HS, Sedmak JJ, et al. Murine interferonbeta receptor-mediated endocytosis and nuclear membrane binding. Proc Natl Acad Sci USA. 1985;82:3281-3285.
    • (1985) Proc Natl Acad Sci USA. , vol.82 , pp. 3281-3285
    • Kushnaryov, V.M.1    MacDonald, H.S.2    Sedmak, J.J.3
  • 17
    • 0027260989 scopus 로고
    • Nuclear muscarinic acetylcholine receptors in corneal cells from rabbit
    • Lind GJ, Cavanagh HD. Nuclear muscarinic acetylcholine receptors in corneal cells from rabbit. Invest Ophthalmol Vis Sci. 1993;34: 2943-2952.
    • (1993) Invest Ophthalmol Vis Sci. , vol.34 , pp. 2943-2952
    • Lind, G.J.1    Cavanagh, H.D.2
  • 18
    • 0342687547 scopus 로고
    • Nerve growth factor in the nucleus: Interaction with receptors on the nuclear membrane
    • Yankner BA, Shooter EM. Nerve growth factor in the nucleus: interaction with receptors on the nuclear membrane. Proc Natl Acad Sci USA. 1979;76:1269-1273.
    • (1979) Proc Natl Acad Sci USA. , vol.76 , pp. 1269-1273
    • Yankner, B.A.1    Shooter, E.M.2
  • 19
    • 0037367841 scopus 로고    scopus 로고
    • Presence of neuropeptide y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: Modulation of intracellular calcium
    • Jacques D, Sader S, Perreault C, et al. Presence of neuropeptide Y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: modulation of intracellular calcium. Can J Physiol Pharmacol. 2003;81:288-300.
    • (2003) Can J Physiol Pharmacol. , vol.81 , pp. 288-300
    • Jacques, D.1    Sader, S.2    Perreault, C.3
  • 21
    • 0033024889 scopus 로고    scopus 로고
    • Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope
    • Bhattacharya M, Peri K, Ribeiro-da-Silva A, et al. Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope. J Biol Chem. 1999;274:15719-15724.
    • (1999) J Biol Chem. , vol.274 , pp. 15719-15724
    • Bhattacharya, M.1    Peri, K.2    Ribeiro-Da-Silva, A.3
  • 22
    • 0141755203 scopus 로고    scopus 로고
    • Modulation of proinflammatory gene expression by nuclear lysophosphatidic acid receptor type-1
    • Gobeil F Jr, Bernier SG, Vazquez-Tello A, et al. Modulation of proinflammatory gene expression by nuclear lysophosphatidic acid receptor type-1. J Biol Chem. 2003;278:38875-38883.
    • (2003) J Biol Chem. , vol.278 , pp. 38875-38883
    • Gobeil, F.1    Bernier, S.G.2    Vazquez-Tello, A.3
  • 23
    • 84856091972 scopus 로고    scopus 로고
    • Biochemical and pharmacological characterization of nuclear urotensin-II binding sites in rat heart
    • Doan ND, Nguyen TT, Letourneau M, et al. Biochemical and pharmacological characterization of nuclear urotensin-II binding sites in rat heart. Br J Pharmacol. 2012;166:243-257.
    • (2012) Br J Pharmacol. , vol.166 , pp. 243-257
    • Doan, N.D.1    Nguyen, T.T.2    Letourneau, M.3
  • 24
    • 84857923121 scopus 로고    scopus 로고
    • Presence of urotensin-II receptors at the cell nucleus: Specific tissue distribution and hypoxiainduced modulation
    • Nguyen TT, Letourneau M, Chatenet D, et al. Presence of urotensin-II receptors at the cell nucleus: specific tissue distribution and hypoxiainduced modulation. Int J Biochem Cell Biol. 2012;44:639-647.
    • (2012) Int J Biochem Cell Biol. , vol.44 , pp. 639-647
    • Nguyen, T.T.1    Letourneau, M.2    Chatenet, D.3
  • 25
    • 0027388870 scopus 로고
    • Novel opioid binding sites associated with nuclei of NG-108-15 neurohybrid cells
    • Belcheva M, Barg J, Rowinski J, et al. Novel opioid binding sites associated with nuclei of NG-108-15 neurohybrid cells. J Neurosci. 1993;13:104-114.
    • (1993) J Neurosci. , vol.13 , pp. 104-114
    • Belcheva, M.1    Barg, J.2    Rowinski, J.3
  • 26
    • 0019779768 scopus 로고
    • Specific nuclear binding of angiotensin II by rat liver and spleen nuclei
    • Re RN, MacPhee AA, Fallon JT. Specific nuclear binding of angiotensin II by rat liver and spleen nuclei. Clin Sci (Lond). 1981;61(suppl 7): 245s-247s.
    • (1981) Clin Sci (Lond). , vol.61 , pp. 245s-247s
    • Re, R.N.1    MacPhee, A.A.2    Fallon, J.T.3
  • 27
    • 0026719124 scopus 로고
    • Characterization of nuclear angiotensin-II-binding sites in rat liver and comparison with plasma membrane receptors
    • Tang SS, Rogg H, Schumacher R, et al. Characterization of nuclear angiotensin-II-binding sites in rat liver and comparison with plasma membrane receptors. Endocrinology. 1992;131:374-380.
    • (1992) Endocrinology. , vol.131 , pp. 374-380
    • Tang, S.S.1    Rogg, H.2    Schumacher, R.3
  • 28
    • 0029811366 scopus 로고    scopus 로고
    • Hepatic angiotensin II nuclear receptors and transcription of growth-related factors
    • Eggena P, Zhu JH, Sereevinyayut S, et al. Hepatic angiotensin II nuclear receptors and transcription of growth-related factors. J Hypertens. 1996;14:961-968.
    • (1996) J Hypertens. , vol.14 , pp. 961-968
    • Eggena, P.1    Zhu, J.H.2    Sereevinyayut, S.3
  • 29
    • 0346362197 scopus 로고    scopus 로고
    • Renal nuclear angiotensin II receptors in normal and hypertensive rats
    • Licea H, Walters MR, Navar LG. Renal nuclear angiotensin II receptors in normal and hypertensive rats. Acta Physiol Hung. 2002;89: 427-438.
    • (2002) Acta Physiol Hung. , vol.89 , pp. 427-438
    • Licea, H.1    Walters, M.R.2    Navar, L.G.3
  • 30
    • 33744781525 scopus 로고    scopus 로고
    • Differential expression of nuclear AT1 receptors and angiotensin II within the kidney of the male congenic mRen2. Lewis rat
    • Pendergrass KD, Averill DB, Ferrario CM, et al. Differential expression of nuclear AT1 receptors and angiotensin II within the kidney of the male congenic mRen2. Lewis rat. Am J Physiol Renal Physiol. 2006; 290:F1497-F1506.
    • (2006) Am J Physiol Renal Physiol. , vol.290 , pp. F1497-F1506
    • Pendergrass, K.D.1    Averill, D.B.2    Ferrario, C.M.3
  • 31
    • 85011480445 scopus 로고    scopus 로고
    • Angiotensin II-induced nuclear targeting of the angiotensin type 1 (AT1) receptor in brain neurons
    • Lu D, Yang H, Shaw G, et al. Angiotensin II-induced nuclear targeting of the angiotensin type 1 (AT1) receptor in brain neurons. Endocrinology. 1998;139:365-375.
    • (1998) Endocrinology. , vol.139 , pp. 365-375
    • Lu, D.1    Yang, H.2    Shaw, G.3
  • 32
    • 0032415076 scopus 로고    scopus 로고
    • Immunohistochemical localization of angiotensin II receptors (AT1) in the heart with anti-peptide antibodies showing a positive chronotropic effect
    • Fu ML, Schulze W, Wallukat G, et al. Immunohistochemical localization of angiotensin II receptors (AT1) in the heart with anti-peptide antibodies showing a positive chronotropic effect. Receptors Channels. 1998;6:99-111.
    • (1998) Receptors Channels. , vol.6 , pp. 99-111
    • Fu, M.L.1    Schulze, W.2    Wallukat, G.3
  • 33
    • 66449132838 scopus 로고    scopus 로고
    • Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production
    • Gwathmey TM, Shaltout HA, Pendergrass KD, et al. Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production. Am J Physiol. 2009;296:F1484-F1493.
    • (2009) Am J Physiol. , vol.296 , pp. F1484-F1493
    • Gwathmey, T.M.1    Shaltout, H.A.2    Pendergrass, K.D.3
  • 34
    • 73849117533 scopus 로고    scopus 로고
    • Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus
    • Gwathmey TM, Pendergrass KD, Reid SD, et al. Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus. Hypertension. 2010;55:166-171.
    • (2010) Hypertension , vol.55 , pp. 166-171
    • Gwathmey, T.M.1    Pendergrass, K.D.2    Reid, S.D.3
  • 35
    • 0026633217 scopus 로고
    • Intracellular distribution of endothelin-1 receptors in rat liver cells
    • Hocher B, Rubens C, Hensen J, et al. Intracellular distribution of endothelin-1 receptors in rat liver cells. Biochem Biophys Res Commun. 1992;184:498-503.
    • (1992) Biochem Biophys Res Commun. , vol.184 , pp. 498-503
    • Hocher, B.1    Rubens, C.2    Hensen, J.3
  • 36
    • 0033732907 scopus 로고    scopus 로고
    • Presence of functional endothelin-1 receptors in nuclear membranes of human aortic vascular smooth muscle cells
    • Bkaily G, Choufani S, Hassan G, et al. Presence of functional endothelin-1 receptors in nuclear membranes of human aortic vascular smooth muscle cells. J Cardiovasc Pharmacol. 2000;36(5 suppl 1): S414-S417.
    • (2000) J Cardiovasc Pharmacol. , vol.36 , Issue.5 , pp. S414-S417
    • Bkaily, G.1    Choufani, S.2    Hassan, G.3
  • 37
    • 0036672467 scopus 로고    scopus 로고
    • Role of endothelin-1 receptors in the sarcolemma membrane and the nuclear membrane in the modulation of basal cytosolic and nuclear calcium levels in heart cells
    • Bkaily G, Massaad D, Choufani S, et al. Role of endothelin-1 receptors in the sarcolemma membrane and the nuclear membrane in the modulation of basal cytosolic and nuclear calcium levels in heart cells. Clin Sci (Lond). 2002;103(suppl 48):141S-147S.
    • (2002) Clin Sci (Lond). , vol.103 , pp. 141S-147S
    • Bkaily, G.1    Massaad, D.2    Choufani, S.3
  • 38
    • 16244410526 scopus 로고    scopus 로고
    • Subcelluar distribution of endothelin signaling pathway components in ventricular myocytes and heart: Lack of preformed caveolar signalosomes
    • Boivin B, Villeneuve LR, Farhat N, et al. Subcelluar distribution of endothelin signaling pathway components in ventricular myocytes and heart: lack of preformed caveolar signalosomes. J Mol Cell Cardiol. 2005;38:665-676.
    • (2005) J Mol Cell Cardiol. , vol.38 , pp. 665-676
    • Boivin, B.1    Villeneuve, L.R.2    Farhat, N.3
  • 39
    • 67650812584 scopus 로고    scopus 로고
    • Expression and localization of endothelin-1 and its receptors in the spiral ganglion neurons of mouse
    • Liu T, Long L, Tang T, et al. Expression and localization of endothelin-1 and its receptors in the spiral ganglion neurons of mouse. Cell Mol Neurobiol. 2009;29:739-745.
    • (2009) Cell Mol Neurobiol. , vol.29 , pp. 739-745
    • Liu, T.1    Long, L.2    Tang, T.3
  • 40
    • 84879816153 scopus 로고    scopus 로고
    • Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca2+ in adult cardiac myocytes
    • Merlen C, Farhat N, Luo X, et al. Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca2+ in adult cardiac myocytes. J Mol Cell Cardiol. 2013;62:189-202.
    • (2013) J Mol Cell Cardiol. , vol.62 , pp. 189-202
    • Merlen, C.1    Farhat, N.2    Luo, X.3
  • 41
    • 0030031180 scopus 로고    scopus 로고
    • Endothelin-1 and angiotensin II receptors in cells from rat hypertrophied heart. Receptor regulation and intracellular Ca2+ modulation
    • Fareh J, Touyz RM, Schiffrin EL, et al. Endothelin-1 and angiotensin II receptors in cells from rat hypertrophied heart. Receptor regulation and intracellular Ca2+ modulation. Circ Res. 1996;78:302-311.
    • (1996) Circ Res. , vol.78 , pp. 302-311
    • Fareh, J.1    Touyz, R.M.2    Schiffrin, E.L.3
  • 42
    • 0037304859 scopus 로고    scopus 로고
    • Both endothelin-A and endothelin-B receptors are present on adult rat cardiac ventricular myocytes
    • Allen BG, Farhat H, Phuong LL, et al. Both endothelin-A and endothelin-B receptors are present on adult rat cardiac ventricular myocytes. Can J Physiol Pharmacol. 2003;81:95-104.
    • (2003) Can J Physiol Pharmacol. , vol.81 , pp. 95-104
    • Allen, B.G.1    Farhat, H.2    Phuong, L.L.3
  • 43
    • 84866923475 scopus 로고    scopus 로고
    • B-Adrenergic regulation of the cardiac Na+-K+ ATPase mediated by oxidative signaling
    • Galougahi KK, Liu CC, Bundgaard H, et al. B-Adrenergic regulation of the cardiac Na+-K+ ATPase mediated by oxidative signaling. Trends Cardiovasc Med. 2012;22:83-87.
    • (2012) Trends Cardiovasc Med. , vol.22 , pp. 83-87
    • Galougahi, K.K.1    Liu, C.C.2    Bundgaard, H.3
  • 44
    • 0033834210 scopus 로고    scopus 로고
    • A functional angiotensin II receptor-GFP fusion protein: Evidence for agonist-dependent nuclear translocation
    • Chen R, Mukhin YV, Garnovskaya MN, et al. A functional angiotensin II receptor-GFP fusion protein: evidence for agonist-dependent nuclear translocation. Am J Physiol Ren Physiol. 2000;279:F440-F448.
    • (2000) Am J Physiol Ren Physiol. , vol.279 , pp. F440-F448
    • Chen, R.1    Mukhin, Y.V.2    Garnovskaya, M.N.3
  • 45
    • 1542289804 scopus 로고    scopus 로고
    • Agonist-independent nuclear localization of the apelin, angiotensin AT1, and bradykinin B2 receptors
    • Lee DK, Lanca AJ, Cheng R, et al. Agonist-independent nuclear localization of the apelin, angiotensin AT1, and bradykinin B2 receptors. J Biol Chem. 2004;279:7901-7908.
    • (2004) J Biol Chem. , vol.279 , pp. 7901-7908
    • Lee, D.K.1    Lanca, A.J.2    Cheng, R.3
  • 46
    • 0025605930 scopus 로고
    • Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor
    • Sakurai T, Yanagisawa M, Takuwa Y, et al. Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature. 1990;348:732-735.
    • (1990) Nature. , vol.348 , pp. 732-735
    • Sakurai, T.1    Yanagisawa, M.2    Takuwa, Y.3
  • 47
    • 0025996825 scopus 로고
    • Endothelin/sarafotoxin receptor heterogeneity: Evidence for different glycosylation in receptors from different tissues
    • Bousso-Mittler D, Galron R, Sokolovsky M. Endothelin/sarafotoxin receptor heterogeneity: evidence for different glycosylation in receptors from different tissues. Biochem Biophys Res Commun. 1991;178:921-926.
    • (1991) Biochem Biophys Res Commun. , vol.178 , pp. 921-926
    • Bousso-Mittler, D.1    Galron, R.2    Sokolovsky, M.3
  • 48
    • 0026739380 scopus 로고
    • A novel subtype of endothelin receptors
    • Sokolovsky M, Ambar I, Galron R. A novel subtype of endothelin receptors. J Biol Chem. 1992;267:20551-20554.
    • (1992) J Biol Chem. , vol.267 , pp. 20551-20554
    • Sokolovsky, M.1    Ambar, I.2    Galron, R.3
  • 49
    • 0034708792 scopus 로고    scopus 로고
    • Subtype-specific trafficking of endothelin receptors
    • Abe Y, Nakayama K, Yamanaka A, et al. Subtype-specific trafficking of endothelin receptors. J Biol Chem. 2000;275:8664-8671.
    • (2000) J Biol Chem. , vol.275 , pp. 8664-8671
    • Abe, Y.1    Nakayama, K.2    Yamanaka, A.3
  • 50
    • 34247346825 scopus 로고    scopus 로고
    • Identification of a putative nuclear localization sequence within ANG II AT1A receptor associated with nuclear activation
    • Morinelli TA, Raymond JR, Baldys A, et al. Identification of a putative nuclear localization sequence within ANG II AT1A receptor associated with nuclear activation. Am J Physiol Cell Physiol. 2007;292:C1398-C1408.
    • (2007) Am J Physiol Cell Physiol. , vol.292 , pp. C1398-C1408
    • Morinelli, T.A.1    Raymond, J.R.2    Baldys, A.3
  • 51
    • 67649845784 scopus 로고    scopus 로고
    • Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs
    • Kosugi S, Hasebe M, Tomita M, et al. Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs. Proc Natl Acad Sci USA. 2009;106:10171-10176.
    • (2009) Proc Natl Acad Sci USA. , vol.106 , pp. 10171-10176
    • Kosugi, S.1    Hasebe, M.2    Tomita, M.3
  • 53
    • 84857820252 scopus 로고    scopus 로고
    • Functional intracellular renin-angiotensin systems: Potential for pathophysiology of disease
    • Carey RM. Functional intracellular renin-angiotensin systems: potential for pathophysiology of disease. Am J Physiol Regul Integr Comp Physiol. 2012;302:R479-R481.
    • (2012) Am J Physiol Regul Integr Comp Physiol. , vol.302 , pp. R479-R481
    • Carey, R.M.1
  • 54
    • 84857888402 scopus 로고    scopus 로고
    • Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model
    • Cook JL, Re RN. Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model. Am J Physiol Regul Integr Comp Physiol. 2012;302:R482-R493.
    • (2012) Am J Physiol Regul Integr Comp Physiol. , vol.302 , pp. R482-R493
    • Cook, J.L.1    Re, R.N.2
  • 55
    • 84863230547 scopus 로고    scopus 로고
    • Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney
    • Ellis B, Li XC, Miguel-Qin E, et al. Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney. Am J Physiol Regul Integr Comp Physiol. 2012;302:R494-R509.
    • (2012) Am J Physiol Regul Integr Comp Physiol. , vol.302 , pp. R494-R509
    • Ellis, B.1    Li, X.C.2    Miguel-Qin, E.3
  • 57
    • 81255157608 scopus 로고    scopus 로고
    • Noncanonical intracrine action
    • Re RN, Cook JL. Noncanonical intracrine action. J Am Soc Hypertens. 2011;5:435-448.
    • (2011) J Am Soc Hypertens. , vol.5 , pp. 435-448
    • Re, R.N.1    Cook, J.L.2
  • 58
    • 80455179690 scopus 로고    scopus 로고
    • Nuclear GPCRs in cardiomyocytes: An insider's view of b-adrenergic receptor signaling
    • Vaniotis G, Allen BG, Hébert TE. Nuclear GPCRs in cardiomyocytes: an insider's view of b-adrenergic receptor signaling. Am J Physiol Heart Circ Physiol. 2011;301:H1754-H1764.
    • (2011) Am J Physiol Heart Circ Physiol. , vol.301 , pp. H1754-H1764
    • Vaniotis, G.1    Allen, B.G.2    Hébert, T.E.3
  • 59
    • 79960290029 scopus 로고    scopus 로고
    • New insights and perspectives on intrarenal reninangiotensin system: Focus on intracrine/intracellular angiotensin II
    • Zhuo JL, Li XC. New insights and perspectives on intrarenal reninangiotensin system: focus on intracrine/intracellular angiotensin II. Peptides. 2011;32:1551-1565.
    • (2011) Peptides. , vol.32 , pp. 1551-1565
    • Zhuo, J.L.1    Li, X.C.2
  • 60
    • 0037023637 scopus 로고    scopus 로고
    • Regulation of eNOS expression in brain endothelial cells by perinuclear EP3 receptors
    • Gobeil F Jr, Dumont I, Marrache AM, et al. Regulation of eNOS expression in brain endothelial cells by perinuclear EP3 receptors. Circ Res. 2002;90:682-689.
    • (2002) Circ Res. , vol.90 , pp. 682-689
    • Gobeil, F.1    Dumont, I.2    Marrache, A.M.3
  • 61
    • 84862874187 scopus 로고    scopus 로고
    • Automated imaging reveals a concentration dependent delay in reversibility of cardiac myocyte hypertrophy
    • Ryall KA, Saucerman JJ. Automated imaging reveals a concentration dependent delay in reversibility of cardiac myocyte hypertrophy. J Mol Cell Cardiol. 2012;53:282-290.
    • (2012) J Mol Cell Cardiol. , vol.53 , pp. 282-290
    • Ryall, K.A.1    Saucerman, J.J.2
  • 62
    • 84904680674 scopus 로고    scopus 로고
    • Nuclear localization of a1A-adrenergic receptors is required for signaling in cardiac myocytes: An inside-out" a1-AR signaling pathway
    • Wu SC, Dahl EF, Wright CD, et al. Nuclear localization of a1A-adrenergic receptors is required for signaling in cardiac myocytes: an "inside-out" a1-AR signaling pathway. J Am Heart Assoc. 2014;3:e000145.
    • (2014) J Am Heart Assoc. , vol.3 , pp. e000145
    • Wu, S.C.1    Dahl, E.F.2    Wright, C.D.3
  • 63
    • 0027491849 scopus 로고
    • Norepinephrine in neonatal rat ventricular myocytes: Association with the cell nucleus and binding to nuclear alpha 1-and beta-adrenergic receptors
    • Buu NT, Hui R, Falardeau P. Norepinephrine in neonatal rat ventricular myocytes: association with the cell nucleus and binding to nuclear alpha 1-and beta-adrenergic receptors. J Mol Cell Cardiol. 1993;25:1037-1046.
    • (1993) J Mol Cell Cardiol. , vol.25 , pp. 1037-1046
    • Buu, N.T.1    Hui, R.2    Falardeau, P.3
  • 64
    • 84878688815 scopus 로고    scopus 로고
    • Regulation of cardiac nitric oxide signaling by nuclear b-adrenergic and endothelin receptors
    • Vaniotis G, Glazkova I, Merlen C, et al. Regulation of cardiac nitric oxide signaling by nuclear b-adrenergic and endothelin receptors. J Mol Cell Cardiol. 2013;62:58-68.
    • (2013) J Mol Cell Cardiol. , vol.62 , pp. 58-68
    • Vaniotis, G.1    Glazkova, I.2    Merlen, C.3
  • 65
    • 33744900324 scopus 로고    scopus 로고
    • Subtype-specific alpha1-and betaadrenoceptor signaling in the heart
    • Xiao RP, Zhu W, Zheng M, et al. Subtype-specific alpha1-and betaadrenoceptor signaling in the heart. Trends Pharmacol Sci. 2006;27:330-337.
    • (2006) Trends Pharmacol Sci. , vol.27 , pp. 330-337
    • Xiao, R.P.1    Zhu, W.2    Zheng, M.3
  • 66
    • 84893345251 scopus 로고    scopus 로고
    • Enhanced expression of b3-adrenoceptors in cardiac myocytes attenuates neurohormoneinduced hypertrophic remodeling through nitric oxide synthase
    • Belge C, Hammond J, Dubois-Deruy E, et al. Enhanced expression of b3-adrenoceptors in cardiac myocytes attenuates neurohormoneinduced hypertrophic remodeling through nitric oxide synthase. Circulation. 2014;129:451-462.
    • (2014) Circulation. , vol.129 , pp. 451-462
    • Belge, C.1    Hammond, J.2    Dubois-Deruy, E.3
  • 67
    • 0019982539 scopus 로고
    • Decreased catecholamine sensitivity and b-adrenergic-receptor density in failing human hearts
    • Bristow MR, Ginsburg R, Minobe W, et al. Decreased catecholamine sensitivity and b-adrenergic-receptor density in failing human hearts. N Engl J Med. 1982;307:205-211.
    • (1982) N Engl J Med. , vol.307 , pp. 205-211
    • Bristow, M.R.1    Ginsburg, R.2    Minobe, W.3
  • 68
    • 0035957302 scopus 로고    scopus 로고
    • Upregulation of b3-adrenoceptors and altered contractile response to inotropic amines in human failing myocardium
    • Moniotte S, Kobzik L, Feron O, et al. Upregulation of b3-adrenoceptors and altered contractile response to inotropic amines in human failing myocardium. Circulation. 2001;103:1649-1655.
    • (2001) Circulation. , vol.103 , pp. 1649-1655
    • Moniotte, S.1    Kobzik, L.2    Feron, O.3
  • 69
    • 0027214427 scopus 로고
    • Endothelin-1 is produced and secreted by neonatal rat cardiac myocytes in vitro
    • Suzuki T, Kumazaki T, Mitsui Y. Endothelin-1 is produced and secreted by neonatal rat cardiac myocytes in vitro. Biochem Biophys Res Commun. 1993;191:823-830.
    • (1993) Biochem Biophys Res Commun. , vol.191 , pp. 823-830
    • Suzuki, T.1    Kumazaki, T.2    Mitsui, Y.3
  • 70
    • 0030474242 scopus 로고    scopus 로고
    • Exogenous effects and endogenous production of endothelin in cardiac myocytes: Potential significance in heart failure
    • Thomas PB, Liu EC, Webb ML, et al. Exogenous effects and endogenous production of endothelin in cardiac myocytes: potential significance in heart failure. Am J Physiol. 1996;271(6 pt 2):H2629-H2637.
    • (1996) Am J Physiol. , vol.271 , Issue.6 , pp. H2629-H2637
    • Thomas, P.B.1    Liu, E.C.2    Webb, M.L.3
  • 71
    • 0034086055 scopus 로고    scopus 로고
    • Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development
    • Yanagisawa H, Hammer RE, Richardson JA, et al. Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development. J Clin Invest. 2000;105:1373-1382.
    • (2000) J Clin Invest. , vol.105 , pp. 1373-1382
    • Yanagisawa, H.1    Hammer, R.E.2    Richardson, J.A.3
  • 72
    • 0033939027 scopus 로고    scopus 로고
    • ET-1 in the myocardial interstitium: Relation to myocyte ECE activity and expression
    • Ergul A, Walker CA, Goldberg A, et al. ET-1 in the myocardial interstitium: relation to myocyte ECE activity and expression. Am J Physiol Heart Circ Physiol. 2000;278:H2050-H2056.
    • (2000) Am J Physiol Heart Circ Physiol. , vol.278 , pp. H2050-H2056
    • Ergul, A.1    Walker, C.A.2    Goldberg, A.3
  • 75
    • 13344287048 scopus 로고    scopus 로고
    • Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy
    • Yamazaki T, Komuro I, Kudoh S, et al. Endothelin-1 is involved in mechanical stress-induced cardiomyocyte hypertrophy. J Biol Chem. 1996;271:3221-3228.
    • (1996) J Biol Chem. , vol.271 , pp. 3221-3228
    • Yamazaki, T.1    Komuro, I.2    Kudoh, S.3
  • 76
    • 0032433193 scopus 로고    scopus 로고
    • Prolonged exercise causes an increase in endothelin-1 production in the heart in rats
    • Maeda S, Miyauchi T, Sakai S, et al. Prolonged exercise causes an increase in endothelin-1 production in the heart in rats. Am J Physiol. 1998;275(6 pt 2):H2105-H2112.
    • (1998) Am J Physiol. , vol.275 , Issue.6 , pp. H2105-H2112
    • Maeda, S.1    Miyauchi, T.2    Sakai, S.3
  • 77
    • 33744912756 scopus 로고    scopus 로고
    • Time course alterations of myocardial endothelin-1 production during the formation of exercise training-induced cardiac hypertrophy
    • Iemitsu M, Maeda S, Otsuki T, et al. Time course alterations of myocardial endothelin-1 production during the formation of exercise training-induced cardiac hypertrophy. Exp Biol Med (Maywood). 2006;231:871-875.
    • (2006) Exp Biol Med (Maywood). , vol.231 , pp. 871-875
    • Iemitsu, M.1    Maeda, S.2    Otsuki, T.3
  • 78
    • 0031640054 scopus 로고    scopus 로고
    • Endothelin-1 expression in hearts of transgenic hypertensive mice overexpressing angiotensin II
    • Maki S, Miyauchi T, Sakai S, et al. Endothelin-1 expression in hearts of transgenic hypertensive mice overexpressing angiotensin II. J Cardiovasc Pharmacol. 1998;31(suppl 1):S412-S416.
    • (1998) J Cardiovasc Pharmacol. , vol.31 , pp. S412-S416
    • Maki, S.1    Miyauchi, T.2    Sakai, S.3
  • 79
    • 0027423417 scopus 로고
    • Increased production of endothelin-1 in the hypertrophied rat heart due to pressure overload
    • Yorikane R, Sakai S, Miyauchi T, et al. Increased production of endothelin-1 in the hypertrophied rat heart due to pressure overload. FEBS Lett. 1993;332:31-34.
    • (1993) FEBS Lett. , vol.332 , pp. 31-34
    • Yorikane, R.1    Sakai, S.2    Miyauchi, T.3
  • 80
    • 0029019736 scopus 로고
    • Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy
    • Arai M, Yoguchi A, Iso T, et al. Endothelin-1 and its binding sites are upregulated in pressure overload cardiac hypertrophy. Am J Physiol. 1995;268:H2084-H2091.
    • (1995) Am J Physiol. , vol.268 , pp. H2084-H2091
    • Arai, M.1    Yoguchi, A.2    Iso, T.3
  • 81
    • 0028884731 scopus 로고
    • Altered production of endothelin-1 in the hypertrophied rat heart
    • Sakai S, Yorikane R, Miyauchi T, et al. Altered production of endothelin-1 in the hypertrophied rat heart. J Cardiovasc Pharmacol. 1995;26:S452-S455.
    • (1995) J Cardiovasc Pharmacol. , vol.26 , pp. S452-S455
    • Sakai, S.1    Yorikane, R.2    Miyauchi, T.3
  • 82
    • 0033834163 scopus 로고    scopus 로고
    • Early sequence of cardiac adaptations and growth factor formation in pressure-and volumeoverload hypertrophy
    • Modesti PA, Vanni S, Bertolozzi I, et al. Early sequence of cardiac adaptations and growth factor formation in pressure-and volumeoverload hypertrophy. Am J Physiol Heart Circ Physiol. 2000;279: H976-H985.
    • (2000) Am J Physiol Heart Circ Physiol. , vol.279 , pp. H976-H985
    • Modesti, P.A.1    Vanni, S.2    Bertolozzi, I.3
  • 83
    • 18644368829 scopus 로고    scopus 로고
    • Altered expression of endothelin receptors in failing human left ventricles
    • Asano K, Bohlmeyer TJ, Westcott JY, et al. Altered expression of endothelin receptors in failing human left ventricles. J Mol Cell Cardiol. 2002;34:833-846.
    • (2002) J Mol Cell Cardiol. , vol.34 , pp. 833-846
    • Asano, K.1    Bohlmeyer, T.J.2    Westcott, J.Y.3
  • 84
    • 0034526430 scopus 로고    scopus 로고
    • Selective upregulation of endothelin converting enzyme-1a in the human failing heart
    • Ergul A, Grubbs AL, Zhang Y, et al. Selective upregulation of endothelin converting enzyme-1a in the human failing heart. J Card Fail. 2000;6:314-320.
    • (2000) J Card Fail. , vol.6 , pp. 314-320
    • Ergul, A.1    Grubbs, A.L.2    Zhang, Y.3
  • 85
    • 0343550386 scopus 로고    scopus 로고
    • Selective upregulation of cardiac endothelin system in patients with ischemic but not idiopathic dilated cardiomyopathy: Endothelin-1 system in the human failing heart
    • Serneri GGN, Cecioni I, Vanni S, et al. Selective upregulation of cardiac endothelin system in patients with ischemic but not idiopathic dilated cardiomyopathy: endothelin-1 system in the human failing heart. Circ Res. 2000;86:377-385.
    • (2000) Circ Res. , vol.86 , pp. 377-385
    • Serneri, G.G.N.1    Cecioni, I.2    Vanni, S.3
  • 86
    • 0033543746 scopus 로고    scopus 로고
    • Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo
    • Kakinuma Y, Miyauchi T, Kobayashi T, et al. Myocardial expression of endothelin-2 is altered reciprocally to that of endothelin-1 during ischemia of cardiomyocytes in vitro and during heart failure in vivo. Life Sci. 1999;65:1671-1683.
    • (1999) Life Sci. , vol.65 , pp. 1671-1683
    • Kakinuma, Y.1    Miyauchi, T.2    Kobayashi, T.3
  • 87
    • 0027337782 scopus 로고
    • Alternatively spliced mRNAs for human endothelin-2 and their tissue distribution
    • O'Reilly G, Charnock-Jones DS, Morrison JJ, et al. Alternatively spliced mRNAs for human endothelin-2 and their tissue distribution. Biochem Biophys Res Commun. 1993;193:834-840.
    • (1993) Biochem Biophys Res Commun. , vol.193 , pp. 834-840
    • O'Reilly, G.1    Charnock-Jones, D.S.2    Morrison, J.J.3
  • 88
    • 0027755230 scopus 로고
    • Characterization of endothelin isoforms in human heart: Endothelin-2 demonstrated
    • Plumpton C, Champeney R, Ashby MJ, et al. Characterization of endothelin isoforms in human heart: endothelin-2 demonstrated. J Cardiovasc Pharmacol. 1993;22(suppl 8):S26-S28.
    • (1993) J Cardiovasc Pharmacol. , vol.22 , pp. S26-S28
    • Plumpton, C.1    Champeney, R.2    Ashby, M.J.3
  • 89
    • 0347383734 scopus 로고    scopus 로고
    • Nuclear localization of endothelin-converting enzyme-1: Subisoform specificity
    • Jafri F, Ergul A. Nuclear localization of endothelin-converting enzyme-1: subisoform specificity. Arterioscler Thromb Vasc Biol. 2003;23: 2192-2196.
    • (2003) Arterioscler Thromb Vasc Biol. , vol.23 , pp. 2192-2196
    • Jafri, F.1    Ergul, A.2
  • 90
    • 33744917249 scopus 로고    scopus 로고
    • Phosphorylation of endothelin converting enzyme-1 isoforms: Relevance to subcellular localization
    • Jafri F, Ergul A. Phosphorylation of endothelin converting enzyme-1 isoforms: relevance to subcellular localization. Exp Biol Med (Maywood). 2006;231:713-717.
    • (2006) Exp Biol Med (Maywood). , vol.231 , pp. 713-717
    • Jafri, F.1    Ergul, A.2
  • 91
    • 0033597946 scopus 로고    scopus 로고
    • Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes in vitro
    • Malhotra R, Sadoshima J, Brosius FC III, et al. Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes in vitro. Circ Res. 1999;85:137-146.
    • (1999) Circ Res. , vol.85 , pp. 137-146
    • Malhotra, R.1    Sadoshima, J.2    Brosius, F.C.3
  • 92
    • 39849106887 scopus 로고    scopus 로고
    • Renin-angiotensin system component expression in the HL-1 atrial cell line and in a pig model of atrial fibrillation
    • Tsai CT, Lai LP, Hwang JJ, et al. Renin-angiotensin system component expression in the HL-1 atrial cell line and in a pig model of atrial fibrillation. J Hypertens. 2008;26:570-582.
    • (2008) J Hypertens. , vol.26 , pp. 570-582
    • Tsai, C.T.1    Lai, L.P.2    Hwang, J.J.3
  • 93
    • 0034463532 scopus 로고    scopus 로고
    • Tissue-specific expression of a rat renin transcript lacking the coding sequence for the prefragment and its stimulation by myocardial infarction
    • Clausmeyer S, Reinecke A, Farrenkopf R, et al. Tissue-specific expression of a rat renin transcript lacking the coding sequence for the prefragment and its stimulation by myocardial infarction. Endocrinology. 2000;141: 2963-2970.
    • (2000) Endocrinology. , vol.141 , pp. 2963-2970
    • Clausmeyer, S.1    Reinecke, A.2    Farrenkopf, R.3
  • 94
    • 0026801950 scopus 로고
    • Detection of angiotensin i and II in cultured rat cardiac myocytes and fibroblasts
    • Dostal DE, Rothblum KN, Conrad KM, et al. Detection of angiotensin I and II in cultured rat cardiac myocytes and fibroblasts. Am J Physiol. 1992;263(4 pt 1):C851-C863.
    • (1992) Am J Physiol. , vol.263 , Issue.4 , pp. C851-C863
    • Dostal, D.E.1    Rothblum, K.N.2    Conrad, K.M.3
  • 95
    • 33644866153 scopus 로고    scopus 로고
    • Expression and localization of N-domain ANG I-converting enzymes in mesangial cells in culture from spontaneously hypertensive rats
    • Camargo de Andrade MC, Di Marco GS, de Paulo Castro Teixeira V, et al. Expression and localization of N-domain ANG I-converting enzymes in mesangial cells in culture from spontaneously hypertensive rats. Am J Physiol Ren Physiol. 2006;290:F364-F375.
    • (2006) Am J Physiol Ren Physiol. , vol.290 , pp. F364-F375
    • Camargo De Andrade, M.C.1    Di Marco, G.S.2    De Paulo Castro Teixeira, V.3
  • 96
    • 0034623856 scopus 로고    scopus 로고
    • Myocardial cell death in human diabetes
    • Frustaci A, Kajstura J, Chimenti C, et al. Myocardial cell death in human diabetes. Circ Res. 2000;87:1123-1132.
    • (2000) Circ Res. , vol.87 , pp. 1123-1132
    • Frustaci, A.1    Kajstura, J.2    Chimenti, C.3
  • 97
    • 34547735173 scopus 로고    scopus 로고
    • High-glucose-induced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes
    • Singh VP, Le B, Bhat VB, et al. High-glucose-induced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes. Am J Physiol. 2007;293:H939-H948.
    • (2007) Am J Physiol. , vol.293 , pp. H939-H948
    • Singh, V.P.1    Le Bhat, B.V.B.2
  • 98
    • 0035490419 scopus 로고    scopus 로고
    • Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death
    • Fiordaliso F, Leri A, Cesselli D, et al. Hyperglycemia activates p53 and p53-regulated genes leading to myocyte cell death. Diabetes. 2001;50: 2363-2375.
    • (2001) Diabetes. , vol.50 , pp. 2363-2375
    • Fiordaliso, F.1    Leri, A.2    Cesselli, D.3
  • 99
    • 41749123049 scopus 로고    scopus 로고
    • Activation of the intracellular reninangiotensin system in cardiac fibroblasts by high glucose: Role in extracellular matrix production
    • Singh VP, Baker KM, Kumar R. Activation of the intracellular reninangiotensin system in cardiac fibroblasts by high glucose: role in extracellular matrix production. Am J Physiol. 2008;294:H1675-H1684.
    • (2008) Am J Physiol. , vol.294 , pp. H1675-H1684
    • Singh, V.P.1    Baker, K.M.2    Kumar, R.3
  • 100
    • 34548319203 scopus 로고    scopus 로고
    • Mechanism of high glucose induced angiotensin II production in rat vascular smooth muscle cells
    • Lavrentyev EN, Estes AM, Malik KU. Mechanism of high glucose induced angiotensin II production in rat vascular smooth muscle cells. Circ Res. 2007;101:455-464.
    • (2007) Circ Res. , vol.101 , pp. 455-464
    • Lavrentyev, E.N.1    Estes, A.M.2    Malik, K.U.3
  • 101
    • 2442681671 scopus 로고    scopus 로고
    • High glucose concentration stimulates intracellular renin activity and angiotensin II generation in rat mesangial cells
    • Vidotti DB, Casarini DE, Cristovam PC, et al. High glucose concentration stimulates intracellular renin activity and angiotensin II generation in rat mesangial cells. Am J Physiol. 2004;286:F1039-F1045.
    • (2004) Am J Physiol. , vol.286 , pp. F1039-F1045
    • Vidotti, D.B.1    Casarini, D.E.2    Cristovam, P.C.3
  • 102
    • 2642560204 scopus 로고    scopus 로고
    • Evidence of a novel intracrine mechanism in angiotensin II-induced cardiac hypertrophy
    • Baker KM, Chernin MI, Schreiber T, et al. Evidence of a novel intracrine mechanism in angiotensin II-induced cardiac hypertrophy. Regul Pept. 2004;120:5-13.
    • (2004) Regul Pept. , vol.120 , pp. 5-13
    • Baker, K.M.1    Chernin, M.I.2    Schreiber, T.3
  • 103
    • 0031811360 scopus 로고    scopus 로고
    • Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system
    • Mazzolai L, Nussberger J, Aubert JF, et al. Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension. 1998;31:1324-1330.
    • (1998) Hypertension. , vol.31 , pp. 1324-1330
    • Mazzolai, L.1    Nussberger, J.2    Aubert, J.F.3
  • 105
    • 58149328554 scopus 로고    scopus 로고
    • Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis
    • Singh VP, Le B, Khode R, et al. Intracellular angiotensin II production in diabetic rats is correlated with cardiomyocyte apoptosis, oxidative stress, and cardiac fibrosis. Diabetes. 2008;57:3297-3306.
    • (2008) Diabetes. , vol.57 , pp. 3297-3306
    • Singh, V.P.1    Le Khode, B.R.2
  • 106
    • 84907320512 scopus 로고    scopus 로고
    • Nuclear expression of reninangiotensin system components in NRK-52E renal epithelial cells
    • Alzayadneh EM, Chappell MC. Nuclear expression of reninangiotensin system components in NRK-52E renal epithelial cells. J Renin Angiotensin Aldosterone Syst. 2014.
    • (2014) J Renin Angiotensin Aldosterone Syst.
    • Alzayadneh, E.M.1    Chappell, M.C.2
  • 107
    • 80052585322 scopus 로고    scopus 로고
    • Identification and characterization of a functional mitochondrial angiotensin system
    • Abadir PM, Foster DB, Crow M, et al. Identification and characterization of a functional mitochondrial angiotensin system. Proc Natl Acad Sci USA. 2011;108:14849-14854.
    • (2011) Proc Natl Acad Sci USA. , vol.108 , pp. 14849-14854
    • Abadir, P.M.1    Foster, D.B.2    Crow, M.3
  • 108
    • 33744941830 scopus 로고    scopus 로고
    • Expression and localization of endothelinconverting enzyme-1 isoforms in human endothelial cells
    • Hunter AR, Turner AJ. Expression and localization of endothelinconverting enzyme-1 isoforms in human endothelial cells. Exp Biol Med. 2006;231:718-722.
    • (2006) Exp Biol Med. , vol.231 , pp. 718-722
    • Hunter, A.R.1    Turner, A.J.2
  • 109
    • 0027432809 scopus 로고
    • Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA
    • Eggena P, Zhu JH, Clegg K, et al. Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA. Hypertension. 1993; 22:496-501.
    • (1993) Hypertension. , vol.22 , pp. 496-501
    • Eggena, P.1    Zhu, J.H.2    Clegg, K.3
  • 110
    • 0021326916 scopus 로고
    • Effect of angiotensin II on RNA synthesis by isolated nuclei
    • Re R, Parab M. Effect of angiotensin II on RNA synthesis by isolated nuclei. Life Sci. 1984;34:647-651.
    • (1984) Life Sci. , vol.34 , pp. 647-651
    • Re, R.1    Parab, M.2
  • 111
    • 41949119685 scopus 로고    scopus 로고
    • Intracellular ANG II directly induces in vitro transcription of TGF-b1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors
    • Li XC, Zhuo JL. Intracellular ANG II directly induces in vitro transcription of TGF-b1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors. Am J Physiol Cell Physiol. 2008;294:C1034-C1045.
    • (2008) Am J Physiol Cell Physiol. , vol.294 , pp. C1034-C1045
    • Li, X.C.1    Zhuo, J.L.2
  • 112
    • 84921725037 scopus 로고    scopus 로고
    • Examining the effects of nuclear GPCRs on gene expression using isolated nuclei
    • Allen BG Hébert TE eds. New York NY: Springer New York
    • Vaniotis G, Gora S, Nantel A, et al. Examining the effects of nuclear GPCRs on gene expression using isolated nuclei. In: Allen BG, Hébert TE, eds. Nuclear G Protein-coupled Receptors: Methods and Protocols. New York, NY: Springer New York; 2015:185-195.
    • (2015) Nuclear G Protein-coupled Receptors: Methods and Protocols , pp. 185-195
    • Vaniotis, G.1    Gora, S.2    Nantel, A.3
  • 113
    • 0035971229 scopus 로고    scopus 로고
    • Nuclear localization of G protein b5 and regulator of G protein signaling 7 in neurons and brain
    • Zhang JH, Barr VA, Mo Y, et al. Nuclear localization of G protein b5 and regulator of G protein signaling 7 in neurons and brain. J Biol Chem. 2001;276:10284-10289.
    • (2001) J Biol Chem. , vol.276 , pp. 10284-10289
    • Zhang, J.H.1    Barr, V.A.2    Mo, Y.3
  • 114
    • 0032520914 scopus 로고    scopus 로고
    • Intracellular distribution of adenylate cyclase in human cardiocytes determined by electron microscopic cytochemistry
    • Yamamoto S, Kawamura K, James TM. Intracellular distribution of adenylate cyclase in human cardiocytes determined by electron microscopic cytochemistry. Microsc Res Tech. 1998;40:479-498.
    • (1998) Microsc Res Tech. , vol.40 , pp. 479-498
    • Yamamoto, S.1    Kawamura, K.2    James, T.M.3
  • 115
    • 0032752177 scopus 로고    scopus 로고
    • Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei
    • Lugnier C, Keravis T, Le Bec A, et al. Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei. Biochim Biophys Acta. 1999;1472:431-446.
    • (1999) Biochim Biophys Acta. , vol.1472 , pp. 431-446
    • Lugnier, C.1    Keravis, T.2    Le Bec, A.3
  • 116
    • 0032514484 scopus 로고    scopus 로고
    • Protein kinase C regulates the nuclear localization of diacylglycerol kinase-z
    • Topham MK, Bunting M, Zimmerman GA, et al. Protein kinase C regulates the nuclear localization of diacylglycerol kinase-z. Nature. 1998;394:697-700.
    • (1998) Nature. , vol.394 , pp. 697-700
    • Topham, M.K.1    Bunting, M.2    Zimmerman, G.A.3
  • 117
    • 0037439942 scopus 로고    scopus 로고
    • CaM kinase IIa mediates norepinephrine-induced translocation of cytosolic phospholipase A2 to the nuclear envelope
    • Fatima S, Yaghini FA, Ahmed A, et al. CaM kinase IIa mediates norepinephrine-induced translocation of cytosolic phospholipase A2 to the nuclear envelope. J Cell Sci. 2003;116:353-365.
    • (2003) J Cell Sci. , vol.116 , pp. 353-365
    • Fatima, S.1    Yaghini, F.A.2    Ahmed, A.3
  • 118
    • 0029841118 scopus 로고    scopus 로고
    • The role of carboxyl-terminal basic amino acids in Gqa-dependent activation, particulate associate, and nuclear localization of phospholipase C-b1
    • Kim CG, Park D, Rhee SG. The role of carboxyl-terminal basic amino acids in Gqa-dependent activation, particulate associate, and nuclear localization of phospholipase C-b1. J Biol Chem. 1996;271: 21187-21192.
    • (1996) J Biol Chem. , vol.271 , pp. 21187-21192
    • Kim, C.G.1    Park, D.2    Rhee, S.G.3
  • 119
    • 0034730764 scopus 로고    scopus 로고
    • A role for nuclear phospholipase Cb1 in cell cycle control
    • Faenza I, Matteucci A, Manzoli L, et al. A role for nuclear phospholipase Cb1 in cell cycle control. J Biol Chem. 2000;275:30520-30524.
    • (2000) J Biol Chem. , vol.275 , pp. 30520-30524
    • Faenza, I.1    Matteucci, A.2    Manzoli, L.3
  • 120
    • 0031046188 scopus 로고    scopus 로고
    • Nuclear translocation of RhoA mediates the mitogen-induced activation of phospholipase D involved in nuclear envelope signal transduction
    • Baldassare JJ, Jarpe MB, Alferes L, et al. Nuclear translocation of RhoA mediates the mitogen-induced activation of phospholipase D involved in nuclear envelope signal transduction. J Biol Chem. 1997;272: 4911-4914.
    • (1997) J Biol Chem. , vol.272 , pp. 4911-4914
    • Baldassare, J.J.1    Jarpe, M.B.2    Alferes, L.3
  • 121
    • 0035172361 scopus 로고    scopus 로고
    • Intracellular localization of phospholipase D1 in mammalian cells
    • Freyberg Z, Sweeney D, Siddhanta A, et al. Intracellular localization of phospholipase D1 in mammalian cells. Mol Biol Cell. 2001;12: 943-955.
    • (2001) Mol Biol Cell. , vol.12 , pp. 943-955
    • Freyberg, Z.1    Sweeney, D.2    Siddhanta, A.3
  • 122
    • 33747617389 scopus 로고    scopus 로고
    • Selective activation of nuclear phospholipase D-1 by G protein-coupled receptor agonists in vascular smooth muscle cells
    • Gayral S, Déléris P, Laulagnier K, et al. Selective activation of nuclear phospholipase D-1 by G protein-coupled receptor agonists in vascular smooth muscle cells. Circ Res. 2006;99:132-139.
    • (2006) Circ Res. , vol.99 , pp. 132-139
    • Gayral, S.1    Déléris, P.2    Laulagnier, K.3
  • 123
    • 0035930577 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase C2a contains a nuclear localization sequence and associates with nuclear speckles
    • Didichenko SA, Thelen M. Phosphatidylinositol 3-kinase C2a contains a nuclear localization sequence and associates with nuclear speckles. J Biol Chem. 2001;276:48135-48142.
    • (2001) J Biol Chem. , vol.276 , pp. 48135-48142
    • Didichenko, S.A.1    Thelen, M.2
  • 124
    • 0142148275 scopus 로고    scopus 로고
    • Through the out door: Nuclear localization of the regulators of G protein signaling
    • Burchett SA. In Through the out door: nuclear localization of the regulators of G protein signaling. J Neurochem. 2003;87:551-559.
    • (2003) J Neurochem. , vol.87 , pp. 551-559
    • Burchett, S.A.1
  • 125
    • 0037020264 scopus 로고    scopus 로고
    • Differential nucleocytoplasmic shuttling of b-arrestins. Characterization of a leucine-rich nuclear export signal in b-arrestin2
    • Scott MG, Le Rouzic E, Perianin A, et al. Differential nucleocytoplasmic shuttling of b-arrestins. Characterization of a leucine-rich nuclear export signal in b-arrestin2. J Biol Chem. 2002;277:37693-37701.
    • (2002) J Biol Chem. , vol.277 , pp. 37693-37701
    • Scott, M.G.1    Le Rouzic, E.2    Perianin, A.3
  • 126
    • 0038514264 scopus 로고    scopus 로고
    • Subcellular localization of b-arrestins is determined by their intact N domain and the nuclear export signal in the C teminus
    • Wang P, Wu Y, Ge X, et al. Subcellular localization of b-arrestins is determined by their intact N domain and the nuclear export signal in the C teminus. J Biol Chem. 2003;278:11648-11653.
    • (2003) J Biol Chem. , vol.278 , pp. 11648-11653
    • Wang, P.1    Wu, Y.2    Ge, X.3
  • 127
    • 0036278332 scopus 로고    scopus 로고
    • Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats
    • Yi XP, Gerdes AM, Li F. Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats. Hypertension. 2002;39: 1058-1063.
    • (2002) Hypertension. , vol.39 , pp. 1058-1063
    • Yi, X.P.1    Gerdes, A.M.2    Li, F.3
  • 128
    • 11344250461 scopus 로고    scopus 로고
    • Myocardial expression and redistribution of GRKs in hypertensive hypertrophy and failure
    • Yi XP, Zhou J, Baker J, et al. Myocardial expression and redistribution of GRKs in hypertensive hypertrophy and failure. Anat Rec A Discov Mol Cell Evol Biol. 2005;282:13-23.
    • (2005) Anat Rec A Discov Mol Cell Evol Biol. , vol.282 , pp. 13-23
    • Yi, X.P.1    Zhou, J.2    Baker, J.3
  • 129
    • 8644290071 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence
    • Johnson LR, Scott MG, Pitcher JA. G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Mol Cell Biol. 2004;24:10169-10179.
    • (2004) Mol Cell Biol. , vol.24 , pp. 10169-10179
    • Johnson, L.R.1    Scott, M.G.2    Pitcher, J.A.3
  • 130
    • 0029588266 scopus 로고
    • Diffusion across the nuclear envelope inhibited by depletion of the nuclear Ca2+ store
    • Stehno-Bittel L, Perez-Terzic C, Clapham DE. Diffusion across the nuclear envelope inhibited by depletion of the nuclear Ca2+ store. Science. 1995;270:1835-1838.
    • (1995) Science. , vol.270 , pp. 1835-1838
    • Stehno-Bittel, L.1    Perez-Terzic, C.2    Clapham, D.E.3
  • 131
    • 0026665955 scopus 로고
    • The calcium pump of liver nuclear membrane is identical to that of endoplasmic reticulum
    • Lanini L, Bachs O, Carafoli E. The calcium pump of liver nuclear membrane is identical to that of endoplasmic reticulum. J Biol Chem. 1992;267:11548-11552.
    • (1992) J Biol Chem. , vol.267 , pp. 11548-11552
    • Lanini, L.1    Bachs, O.2    Carafoli, E.3
  • 132
    • 0033824618 scopus 로고    scopus 로고
    • Nucleoplasmic Ca2+ loading is regulated by mobilization of perinuclear Ca2+
    • Abrenica B, Gilchrist JSC. Nucleoplasmic Ca2+ loading is regulated by mobilization of perinuclear Ca2+. Cell Calcium. 2000;28:127-136.
    • (2000) Cell Calcium. , vol.28 , pp. 127-136
    • Abrenica, B.1    Gilchrist, J.S.C.2
  • 133
    • 0030805938 scopus 로고    scopus 로고
    • Does the nuclear envelope contain two types of ligand-gated Ca2+ release channels?
    • Guihard G, Proteau S, Rousseau E. Does the nuclear envelope contain two types of ligand-gated Ca2+ release channels? FEBS Lett. 1997;414: 89-94.
    • (1997) FEBS Lett. , vol.414 , pp. 89-94
    • Guihard, G.1    Proteau, S.2    Rousseau, E.3
  • 134
    • 18144391476 scopus 로고    scopus 로고
    • Cardiac type 2 inositol 1,4,5-trisphosphate receptor: Interaction and modulation by calcium/calmodulin-dependent protein kinase II
    • Bare DJ, Kettlun CS, Liang M, et al. Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II. J Biol Chem. 2005;280: 15912-15920.
    • (2005) J Biol Chem. , vol.280 , pp. 15912-15920
    • Bare, D.J.1    Kettlun, C.S.2    Liang, M.3
  • 135
    • 69649105673 scopus 로고    scopus 로고
    • An update on nuclear calcium signaling
    • Bootman MD, Fearnley C, Smyrnias I, et al. An update on nuclear calcium signaling. J Cell Sci. 2009;122(pt 14):2337-2350.
    • (2009) J Cell Sci. , vol.122 , pp. 2337-2350
    • Bootman, M.D.1    Fearnley, C.2    Smyrnias, I.3
  • 136
    • 84922696205 scopus 로고    scopus 로고
    • An integrated mechanism of cardiomyocyte nuclear Ca2+ signaling
    • Ibarra C, Vicencio JM, Varas-Godoy M, et al. An integrated mechanism of cardiomyocyte nuclear Ca2+ signaling. J Mol Cell Cardiol. 2014;75: 40-48.
    • (2014) J Mol Cell Cardiol. , vol.75 , pp. 40-48
    • Ibarra, C.1    Vicencio, J.M.2    Varas-Godoy, M.3
  • 137
    • 33644641253 scopus 로고    scopus 로고
    • Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling
    • Wu X, Zhang T, Bossuyt J, et al. Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest. 2006;116:675-682.
    • (2006) J Clin Invest. , vol.116 , pp. 675-682
    • Wu, X.1    Zhang, T.2    Bossuyt, J.3
  • 138
    • 0028037275 scopus 로고
    • Nuclear lipid metabolism in NEST: Nuclear envelope signal transduction
    • Raben DM, Jarpe MB, Leach KL. Nuclear lipid metabolism in NEST: nuclear envelope signal transduction. Membr Biol. 1994;142:1-7.
    • (1994) Membr Biol. , vol.142 , pp. 1-7
    • Raben, D.M.1    Jarpe, M.B.2    Leach, K.L.3
  • 139
    • 0037125879 scopus 로고    scopus 로고
    • Nuclear lipid signaling
    • Irvine RF. Nuclear lipid signaling. Sci STKE. 2002;150:RE13.
    • (2002) Sci STKE. , vol.150 , pp. RE13
    • Irvine, R.F.1
  • 140
    • 0028967442 scopus 로고
    • Photolabile caged adrenergic receptor agonists and related model compounds
    • Muralidharan S, Nerbonne JM. Photolabile "caged" adrenergic receptor agonists and related model compounds. J Photochem Photobiol B. 1995;27:123-137.
    • (1995) J Photochem Photobiol B. , vol.27 , pp. 123-137
    • Muralidharan, S.1    Nerbonne, J.M.2
  • 141
    • 84921770581 scopus 로고    scopus 로고
    • Design and application of lightactivated probes for cellular signaling
    • Allen BG Hébert TE eds. New York NY: Springer New York
    • Chatenet D, Bourgault S, Fournier A. Design and application of lightactivated probes for cellular signaling. In: Allen BG, Hébert TE, eds. Nuclear G Protein-coupled Receptors: Methods and Protocols. New York, NY: Springer New York; 2015:17-30.
    • (2015) Nuclear G Protein-coupled Receptors: Methods and Protocols , pp. 17-30
    • Chatenet, D.1    Bourgault, S.2    Fournier, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.