Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca2+ in adult cardiac myocytes

Journal of Molecular and Cellular Cardiology

Volumn 62, Issue , 2013, Pages 189-202

  Merlen, Clémence ^a,b   Farhat, Nada ^a   Luo, Xiaoyan ^a,b   Chatenet, David ^d   Tadevosyan, Artavazd ^a,b   Villeneuve, Louis R ^a   Gillis, Marc Antoine ^a   Nattel, Stanley ^a,b,e   Thorin, Eric ^a,b,c   Fournier, Alain ^d   Allen, Bruce G ^a,b,e  

^a MONTREAL HEART INSTITUTE   (Canada)

^b Department of Biochemistry ^*  (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITÉ LAVAL   (Canada)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

Endothelin receptor; Nuclear Ca2+; Nuclear envelope; Receptor trafficking; Stimulus transcription coupling

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; ENDOTHELIN; ENDOTHELIN RECEPTOR; ENDOTHELIN TYPE A RECEPTOR; ENDOTHELIN TYPE B RECEPTOR; GLYCOSIDASE; INOSITOL 1,4,5 TRISPHOSPHATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; IRL 2500; N GLYCOSIDASE F; RYANODINE; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; AORTA; ARTICLE; CALCIUM SIGNALING; CELL NUCLEOPLASM; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ENDOCYTOSIS; ENDOTHELIUM CELL; GLYCOSYLATION; NONHUMAN; PHOTOLYSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RAT;

Α-ADRENERGIC RECEPTOR; Α-AR; 1,3-DICYCLOHEXYLCARBODIIMIDE; 2-AMINOETHOXYDIPHENYL BORATE; 2-APB; 4,5-DIMETHOXYNITROBENZYL GROUP; [CA(2+)](N); [TRP-ODMNB(21)]ET-1; ANG II; ANGIOTENSIN II; CA(2+)/CALMODULIN-DEPENDENT PROTEIN KINASE II; CAGED ET-1; CAMKII; CET-1; DCC; DCM; DEOXYRIBONUCLEIC ACID; DICHLOROMETHANE; DITHIOTHREITOL; DMNB; DNA; DTT; ECE1-A; ENDOTHELIN 1; ENDOTHELIN 2; ENDOTHELIN 3; ENDOTHELIN CONVERTING ENZYME 1A; ENDOTHELIN RECEPTOR; ENDOTHELIN TYPE A RECEPTOR; ENDOTHELIN TYPE B RECEPTOR; ET-1; ET-2; ET-3; ETA; ETB; ETR; G PROTEIN-COUPLED RECEPTOR; GPCR; HDAC5; HISTONE DEACETYLASE 5; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR; IP3; IP3R; ISO; ISOPROTERENOL; MEF2; MYOCYTE ENHANCING FACTOR-2; NUCLEAR CA(2+); NUCLEAR ENVELOPE; NUCLEOPLASMIC FREE CALCIUM CONCENTRATION; PBS; PEPTIDE N-GLYCOSIDASE F; PHENYLMETHANESULFONYL FLUORIDE; PHOSPHATE BUFFERED SALINE; PMSF; PNGASE F; QPCR; QUANTITATIVE REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR TRAFFICKING; RIBONUCLEIC ACID; RNA; RYANODINE RECEPTOR; RYR; STIMULUS-TRANSCRIPTION COUPLING; TCA; TFA; TRICHLOROACETIC ACID; TRIFLUOROACETIC ACID; TRITON X-100; TX-100;

ANIMALS; AORTA; CALCIUM; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELINS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MICROSCOPY, CONFOCAL; MYOCYTES, CARDIAC; NUCLEAR ENVELOPE; RATS; RECEPTORS, ENDOTHELIN; RYANODINE;

RATTUS;

EID: 84879816153     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.05.021     Document Type: Article

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