Intracellular localization of phospholipase D1 in mammalian cells

Molecular Biology of the Cell

Volumn 12, Issue 4, 2001, Pages 943-955

  Freyberg, Z ^a   Sweeney, D ^a   Siddhanta, A ^a   Bourgoin, S ^a   Frohman, M ^a   Shields, D ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREFELDIN A; CHIMERIC PROTEIN; HEMAGGLUTININ; NOCODAZOLE; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE D1;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; GENE OVEREXPRESSION; GOLGI COMPLEX; INTRACELLULAR TRANSPORT; LYSOSOME; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0035172361     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.4.943     Document Type: Article

References (32)

1. Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors
2. A phospholipase D-mediated pathway for generating diacylglycerol in nuclei from Madin-Darby canine kidney cells
3. Nuclear translocation of RhoA mediates the mitogen-induced activation of phospholipase D involved in nuclear envelope signal transduction
4. Phosphoinositide. Signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors
5. Phospholipase D1 localizes to secretory granules and lysosomes and is plasma-membrane translocated on cellular stimulation
6. Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network
7. Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization
8. Phosphoinositides as regulators in membrane traffic
9. Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family
10. Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha
11. Phospholipase D regulation and localization is dependent upon a phosphatidylinositol 4,5-biphosphate-specific PH domain
12. Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the Golgi compartment
13. Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid
14. Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A
15. Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles
16. Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER
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18. Phospholipase D: Molecular and cell biology of a novel gene family
19. The mitotic phosphorylation cycle of the cis-Golgi matrix protein GM130
20. Human phospholipase D1 can be tyrosine-phosphorylated in HL-60 granulocytes
21. The pro-apoptotic drug camptothecin stimulates phospholipase D activity and diacylglycerol production in the nucleus of HL-60 human promyelocytic leukemia cells
22. Phosphatidylinositol 4,5-bisphosphate synthesis is required for activation of phospholipase D in U937 cells
23. Inhibition of phosphatidic acid synthesis alters the structure of the Golgi apparatus and inhibits secretion in endocrine cells
24. Secretory vesicle budding from the trans-Golgi network is mediated by phosphatidic acid levels
25. Purification of rat liver Golgi stacks
26. ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of ccatomer-coated vesicles
27. Colocalization of phospholipase D1 and the GTP-binding-defective mutant of the ADP-ribosylation factor 6 to endosomes and lysosomes
28. Phospholipase D in cellular senescence
29. The measurement of phospholipase D-linked signaling in cells
30. Prohormone processing in the trans-Golgi network: Endoproteolytic cleavage of prosomatostatin and formation of nascent secretory vesicles in permeabilized cells
31. Interaction of the small G protein RhoA with the C terminus of human phospholipase D1
32. Scattered Golgi elements during microtubule disruption are initially enriched in trans-Golgi proteins