Canonical Non-Homologous End Joining in Mitosis Induces Genome Instability and Is Suppressed by M-phase-Specific Phosphorylation of XRCC4

PLoS Genetics

Volumn 10, Issue 8, 2014, Pages

  Terasawa, Masahiro ^a   Shinohara, Akira ^a   Shinohara, Miki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; C TERMINAL BINDING PROTEIN INTERACTING PROTEIN; CYCLIN DEPENDENT KINASE; LIGASE; LIGASE 4; POLO LIKE KINASE 1; UNCLASSIFIED DRUG; XRCC4 PROTEIN; DNA BINDING PROTEIN; XRCC4 PROTEIN, HUMAN;

ANAPHASE; ARTICLE; CELL CYCLE M PHASE; CHROMOSOMAL INSTABILITY; COMPLEX FORMATION; CONTROLLED STUDY; DICENTRIC CHROMOSOME; DNA END JOINING REPAIR; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; MITOSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; DNA REPAIR; DOUBLE STRANDED DNA BREAK; GENETICS; HELA CELL LINE; HOMOLOGOUS RECOMBINATION; M PHASE CELL CYCLE CHECKPOINT; PHOSPHORYLATION;

DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; DNA REPAIR; DNA-BINDING PROTEINS; G1 PHASE; G2 PHASE; GENOMIC INSTABILITY; HELA CELLS; HOMOLOGOUS RECOMBINATION; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MITOSIS; PHOSPHORYLATION;

EID: 84922718893     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004563     Document Type: Article

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