-
1
-
-
4544342570
-
Nuclear factor-kappaB: The enemy within
-
Aggarwal BB (2004) Nuclear factor-kappaB: the enemy within. Cancer Cell 6:203-8
-
(2004)
Cancer Cell
, vol.6
, pp. 203-208
-
-
Aggarwal, B.B.1
-
2
-
-
84892490267
-
NFkappaB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC
-
Almeida LO, Abrahao AC, Rosselli-Murai LK et al. (2014) NFkappaB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC) FEBS Open Bio 4:96-104
-
(2014)
FEBS Open Bio
, vol.4
, pp. 96-104
-
-
Almeida, L.O.1
Abrahao, A.C.2
Rosselli-Murai, L.K.3
-
3
-
-
77953912896
-
Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFkappaB activation via Src-dependent blockade of PP2A
-
Barisic S, Schmidt C, Walczak H et al. (2010) Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFkappaB activation via Src-dependent blockade of PP2A. Biochem Pharmacol 80:439-47
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 439-447
-
-
Barisic, S.1
Schmidt, C.2
Walczak, H.3
-
4
-
-
54049115864
-
Identification of PP2A as a crucial regulator of the NF-kappaB feedback loop: Its inhibition by UVB turns NF-kappaB into a pro-Apoptotic factor
-
Barisic S, Strozyk E, Peters N et al. (2008) Identification of PP2A as a crucial regulator of the NF-kappaB feedback loop: its inhibition by UVB turns NF-kappaB into a pro-Apoptotic factor. Cell Death Differ 15:1681-90
-
(2008)
Cell Death Differ
, vol.15
, pp. 1681-1690
-
-
Barisic, S.1
Strozyk, E.2
Peters, N.3
-
5
-
-
2942716907
-
P53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1
-
Bohuslav J, Chen LF, Kwon H et al. (2004) p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. J Biol Chem 279:26115-25
-
(2004)
J Biol Chem
, vol.279
, pp. 26115-26125
-
-
Bohuslav, J.1
Chen, L.F.2
Kwon, H.3
-
6
-
-
1842526076
-
Active repression of antiapoptotic gene expression by RelA(p65
-
Campbell KJ, Rocha S, Perkins ND (2004) Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. Mol Cell 13:853-65
-
(2004)
NF-kappa B. Mol Cell
, vol.13
, pp. 853-865
-
-
Campbell, K.J.1
Rocha, S.2
Perkins, N.D.3
-
7
-
-
0033537719
-
Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation
-
Delhase M, Hayakawa M, Chen Y et al. (1999) Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation. Science 284:309-13
-
(1999)
Science
, vol.284
, pp. 309-313
-
-
Delhase, M.1
Hayakawa, M.2
Chen, Y.3
-
8
-
-
34047201494
-
Mutant p53: From guardian to fallen angel?
-
Deppert W (2007) Mutant p53: from guardian to fallen angel? Oncogene 26:2142-4
-
(2007)
Oncogene
, vol.26
, pp. 2142-2144
-
-
Deppert, W.1
-
9
-
-
34250835251
-
The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes
-
Feldmeyer L, Keller M, Niklaus G et al. (2007) The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr Biol 17:1140-5
-
(2007)
Curr Biol
, vol.17
, pp. 1140-1145
-
-
Feldmeyer, L.1
Keller, M.2
Niklaus, G.3
-
10
-
-
77954905782
-
Imaging CREB activation in living cells
-
Friedrich MW, Aramuni G, Mank M et al. (2010) Imaging CREB activation in living cells. J Biol Chem 285:23285-95
-
(2010)
J Biol Chem
, vol.285
, pp. 23285-23295
-
-
Friedrich, M.W.1
Aramuni, G.2
Mank, M.3
-
11
-
-
84872665123
-
Desensitization of NFkappaB for overcoming chemoresistance of pancreatic cancer cells to TNF-Alpha or paclitaxel
-
Fujioka S, Son K, Onda S et al. (2012) Desensitization of NFkappaB for overcoming chemoresistance of pancreatic cancer cells to TNF-Alpha or paclitaxel. Anticancer Res 32:4813-21
-
(2012)
Anticancer Res
, vol.32
, pp. 4813-4821
-
-
Fujioka, S.1
Son, K.2
Onda, S.3
-
12
-
-
0025149165
-
In vitro transformation of human skin epithelial cells: Role of RAS oncogene in malignant progression
-
Fusenig NE, Boukamp P, Breitkreutz D et al. (1990) In vitro transformation of human skin epithelial cells: role of RAS oncogene in malignant progression. Toxicol In Vitro 4:627-34
-
(1990)
Toxicol in Vitro
, vol.4
, pp. 627-634
-
-
Fusenig, N.E.1
Boukamp, P.2
Breitkreutz, D.3
-
14
-
-
14844333605
-
Mutant p53 proteins bind DNA in a DNA structure-selective mode
-
Goehler T, Jaeger S, Warnecke G et al. (2005) Mutant p53 proteins bind DNA in a DNA structure-selective mode. Nucleic Acids Res 33: 1087-100
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 1087-1100
-
-
Goehler, T.1
Jaeger, S.2
Warnecke, G.3
-
15
-
-
26444538871
-
The two faces of NFkappaB in cell survival responses
-
Graham B, Gibson SB (2005) The two faces of NFkappaB in cell survival responses. Cell Cycle 4:1342-5
-
(2005)
Cell Cycle
, vol.4
, pp. 1342-1345
-
-
Graham, B.1
Gibson, S.B.2
-
16
-
-
77953755226
-
P53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress
-
Gurzov EN, Germano CM, Cunha DA et al. (2010) p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress. J Biol Chem 285:19910-20
-
(2010)
J Biol Chem
, vol.285
, pp. 19910-19920
-
-
Gurzov, E.N.1
Germano, C.M.2
Cunha, D.A.3
-
17
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: Temporal control and selective gene activation
-
Hoffmann A, Levchenko A, Scott ML et al. (2002) The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 298:1241-5
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
-
18
-
-
34047248402
-
Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB
-
Huang WC, Ju TK, Hung MC et al. (2007) Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB. Mol Cell 26:75-87
-
(2007)
Mol Cell
, vol.26
, pp. 75-87
-
-
Huang, W.C.1
Ju, T.K.2
Hung, M.C.3
-
19
-
-
0034616639
-
P300/CBP-dependent and-independent transcriptional interference between NF-kappaB RelA and p53
-
Ikeda A, Sun X, Li Y et al. (2000) p300/CBP-dependent and-independent transcriptional interference between NF-kappaB RelA and p53. Biochem Biophys Res Commun 272:375-9
-
(2000)
Biochem Biophys Res Commun
, vol.272
, pp. 375-379
-
-
Ikeda, A.1
Sun, X.2
Li, Y.3
-
20
-
-
44649108882
-
Activated p53 induces NFkappaB DNA binding but suppresses its transcriptional activation
-
Kawauchi K, Araki K, Tobiume K et al. (2008) Activated p53 induces NFkappaB DNA binding but suppresses its transcriptional activation. Biochem Biophys Res Commun 372:137-41
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 137-141
-
-
Kawauchi, K.1
Araki, K.2
Tobiume, K.3
-
21
-
-
34047223509
-
Interactions of mutant p53 with DNA: Guilt by association
-
Kim E, Deppert W (2007) Interactions of mutant p53 with DNA: guilt by association. Oncogene 26:2185-90
-
(2007)
Oncogene
, vol.26
, pp. 2185-2190
-
-
Kim, E.1
Deppert, W.2
-
22
-
-
76249103598
-
Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia
-
Klein AM, Brash DE, Jones PH et al. (2010) Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia. Proc Natl Acad Sci USA 107:270-5
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 270-275
-
-
Klein, A.M.1
Brash, D.E.2
Jones, P.H.3
-
23
-
-
84897385754
-
Identification of new IkappaBalpha complexes by an iterative experimental and mathematical modeling approach
-
Konrath F, Witt J, Sauter T et al. (2014) Identification of new IkappaBalpha complexes by an iterative experimental and mathematical modeling approach. PLoS Comput Biol 10:e1003528
-
(2014)
PLoS Comput Biol
, vol.10
, pp. e1003528
-
-
Konrath, F.1
Witt, J.2
Sauter, T.3
-
25
-
-
0032969001
-
Transcriptional regulation of T lymphocyte development and function
-
Kuo CT, Leiden JM (1999) Transcriptional regulation of T lymphocyte development and function. Annu Rev Immunol 17:149-87
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 149-187
-
-
Kuo, C.T.1
Leiden, J.M.2
-
26
-
-
0027159540
-
P53 mutations in human immortalized epithelial cell lines
-
Lehman TA, Modali R, Boukamp P et al. (1993) p53 mutations in human immortalized epithelial cell lines. Carcinogenesis 14:833-9
-
(1993)
Carcinogenesis
, vol.14
, pp. 833-839
-
-
Lehman, T.A.1
Modali, R.2
Boukamp, P.3
-
27
-
-
0037376895
-
NF-kappaB in cancer: A marked target
-
Lin A, Karin M (2003) NF-kappaB in cancer: a marked target. Semin Cancer Biol 13:107-14
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 107-114
-
-
Lin, A.1
Karin, M.2
-
28
-
-
32444447358
-
NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta
-
Liu J, Yang D, Minemoto Y et al. (2006) NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta. Mol Cell 21:467-80
-
(2006)
Mol Cell
, vol.21
, pp. 467-480
-
-
Liu, J.1
Yang, D.2
Minemoto, Y.3
-
29
-
-
41949139309
-
Induction of p21 by p65 in p53 null cells treated with Doxorubicin
-
Ma S, Tang J, Feng J et al. (2008) Induction of p21 by p65 in p53 null cells treated with Doxorubicin. Biochim Biophys Acta 1783:935-40
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 935-940
-
-
Ma, S.1
Tang, J.2
Feng, J.3
-
30
-
-
84880309607
-
Not all p53 gain-of-function mutants are created equal
-
Mello SS, Attardi LD (2013) Not all p53 gain-of-function mutants are created equal. Cell Death Differ 20:855-7
-
(2013)
Cell Death Differ
, vol.20
, pp. 855-857
-
-
Mello, S.S.1
Attardi, L.D.2
-
31
-
-
27544486327
-
Transcription-independent proapoptotic functions of p53
-
Moll UM, Wolff S, Speidel D et al. (2005) Transcription-independent proapoptotic functions of p53. Curr Opin Cell Biol 17:631-6
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 631-636
-
-
Moll, U.M.1
Wolff, S.2
Speidel, D.3
-
33
-
-
0035001698
-
The molecular determinants of sunburn cell formation
-
Murphy G, Young AR, Wulf HC et al. (2001) The molecular determinants of sunburn cell formation. Exp Dermatol 10:155-60
-
(2001)
Exp Dermatol
, vol.10
, pp. 155-160
-
-
Murphy, G.1
Young, A.R.2
Wulf, H.C.3
-
34
-
-
84890205004
-
Reactive oxygen species activate NFkappaB (p65) and p53 and induce apoptosis in RVFV infected liver cells
-
Narayanan A, Amaya M, Voss K et al. (2014) Reactive oxygen species activate NFkappaB (p65) and p53 and induce apoptosis in RVFV infected liver cells. Virology 449:270-86
-
(2014)
Virology
, vol.449
, pp. 270-286
-
-
Narayanan, A.1
Amaya, M.2
Voss, K.3
-
35
-
-
77953532933
-
P53-mediated induction of Noxa and p53AIP1 requires NFkappaB
-
O'Prey J, Crighton D, Martin AG et al. (2010) p53-mediated induction of Noxa and p53AIP1 requires NFkappaB. Cell Cycle 9:947-52
-
(2010)
Cell Cycle
, vol.9
, pp. 947-952
-
-
O'prey, J.1
Crighton, D.2
Martin, A.G.3
-
36
-
-
18144371109
-
NFkB-dependent downregulation of tumor necrosis factor receptor-Associated proteins contributes to interleukin-1-mediated enhancement of ultraviolet B-induced apoptosis
-
Poppelmann B, Klimmek K, Strozyk E et al. (2005) NFkB-dependent downregulation of tumor necrosis factor receptor-Associated proteins contributes to interleukin-1-mediated enhancement of ultraviolet B-induced apoptosis. J Biol Chem 280:15635-43
-
(2005)
J Biol Chem
, vol.280
, pp. 15635-15643
-
-
Poppelmann, B.1
Klimmek, K.2
Strozyk, E.3
-
37
-
-
84864533044
-
The DNA binding and accumulation of p53 from breast cancer cell lines and the link with serine 15 phosphorylation
-
Ray D, Murphy KR, Gal S (2012) The DNA binding and accumulation of p53 from breast cancer cell lines and the link with serine 15 phosphorylation. Cancer Biol Ther 13:848-57
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 848-857
-
-
Ray, D.1
Murphy, K.R.2
Gal, S.3
-
38
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
Ryan KM, Ernst MK, Rice NR et al. (2000) Role of NF-kappaB in p53-mediated programmed cell death. Nature 404:892-7
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
-
39
-
-
77952424136
-
Cross talk between stimulated NF-kappaB and the tumor suppressor p53
-
Schneider G, Henrich A, Greiner G et al. (2010) Cross talk between stimulated NF-kappaB and the tumor suppressor p53. Oncogene 29: 2795-806
-
(2010)
Oncogene
, vol.29
, pp. 2795-2806
-
-
Schneider, G.1
Henrich, A.2
Greiner, G.3
-
40
-
-
77949879162
-
Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway
-
Seitz SJ, Schleithoff ES, Koch A et al. (2010) Chemotherapy-induced apoptosis in hepatocellular carcinoma involves the p53 family and is mediated via the extrinsic and the intrinsic pathway. Int J Cancer 126:2049-66
-
(2010)
Int J Cancer
, vol.126
, pp. 2049-2066
-
-
Seitz, S.J.1
Schleithoff, E.S.2
Koch, A.3
-
41
-
-
35148826938
-
Shaping genetic alterations in human cancer: The p53 mutation paradigm
-
Soussi T, Wiman KG (2007) Shaping genetic alterations in human cancer: the p53 mutation paradigm. Cancer Cell 12:303-12
-
(2007)
Cancer Cell
, vol.12
, pp. 303-312
-
-
Soussi, T.1
Wiman, K.G.2
-
42
-
-
77951934059
-
Cooperation of NFkappaB and CREB to induce synergistic IL-6 expression in astrocytes
-
Spooren A, Kooijman R, Lintermans B et al. (2010) Cooperation of NFkappaB and CREB to induce synergistic IL-6 expression in astrocytes. Cell Signal 22:871-81
-
(2010)
Cell Signal
, vol.22
, pp. 871-881
-
-
Spooren, A.1
Kooijman, R.2
Lintermans, B.3
-
43
-
-
33749868608
-
Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: The type of DNA damage determines the final outcome
-
Strozyk E, Poppelmann B, Schwarz T et al. (2006) Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome. Oncogene 25:6239-51
-
(2006)
Oncogene
, vol.25
, pp. 6239-6251
-
-
Strozyk, E.1
Poppelmann, B.2
Schwarz, T.3
-
44
-
-
58149487765
-
TNFalpha-induced activation of NFkappaB protects against UV-induced apoptosis specifically in p53-proficient cells
-
Szoltysek K, Pietranek K, Kalinowska-Herok M et al. (2008) TNFalpha-induced activation of NFkappaB protects against UV-induced apoptosis specifically in p53-proficient cells. Acta Biochim Pol 55:741-8
-
(2008)
Acta Biochim Pol
, vol.55
, pp. 741-748
-
-
Szoltysek, K.1
Pietranek, K.2
Kalinowska-Herok, M.3
-
45
-
-
71749094946
-
P53 and NFkappaB: Fresh breath in the cross talk
-
Tergaonkar V (2009) p53 and NFkappaB: fresh breath in the cross talk. Cell Res 19:1313-5
-
(2009)
Cell Res
, vol.19
, pp. 1313-1315
-
-
Tergaonkar, V.1
-
46
-
-
0036599406
-
P53 stabilization is decreased upon NFkappaB activation: A role for NFkappaB in acquisition of resistance to chemotherapy
-
Tergaonkar V, Pando M, Vafa O et al. (2002) p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy. Cancer Cell 1:493-503
-
(2002)
Cancer Cell
, vol.1
, pp. 493-503
-
-
Tergaonkar, V.1
Pando, M.2
Vafa, O.3
-
48
-
-
69049103034
-
PUMA is directly activated by NF-kappaB and contributes to TNF-Alpha-induced apoptosis
-
Wang P, Qiu W, Dudgeon C et al. (2009) PUMA is directly activated by NF-kappaB and contributes to TNF-Alpha-induced apoptosis. Cell Death Differ 16:1192-202
-
(2009)
Cell Death Differ
, vol.16
, pp. 1192-1202
-
-
Wang, P.1
Qiu, W.2
Dudgeon, C.3
-
49
-
-
0032954928
-
Transcriptional cross talk between NF-kappaB and p53
-
Webster GA, Perkins ND (1999) Transcriptional cross talk between NF-kappaB and p53. Mol Cell Biol 19:3485-95
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3485-3495
-
-
Webster, G.A.1
Perkins, N.D.2
-
50
-
-
34047263449
-
Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells
-
Weisz L, Damalas A, Liontos M et al. (2007) Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells. Cancer Res 67:2396-401
-
(2007)
Cancer Res
, vol.67
, pp. 2396-2401
-
-
Weisz, L.1
Damalas, A.2
Liontos, M.3
-
51
-
-
68949206434
-
Mechanism of PP2A-mediated IKKbeta dephosphorylation: A systems biological approach
-
Witt J, Barisic S, Schumann E et al. (2009) Mechanism of PP2A-mediated IKKbeta dephosphorylation: a systems biological approach. BMC Syst Biol 3:71
-
(2009)
BMC Syst Biol
, vol.3
, pp. 71
-
-
Witt, J.1
Barisic, S.2
Schumann, E.3
-
52
-
-
0030048230
-
DNA repair and cytokines in antimutagenesis and anticarcinogenesis
-
Yarosh DB, Kripke ML (1996) DNA repair and cytokines in antimutagenesis and anticarcinogenesis. Mutat Res 350:255-60
-
(1996)
Mutat Res
, vol.350
, pp. 255-260
-
-
Yarosh, D.B.1
Kripke, M.L.2
-
53
-
-
0042337367
-
Mutant p53 gain of function: Repression of CD95(Fas/APO-1) gene expression by tumorassociated p53 mutants
-
Zalcenstein A, Stambolsky P, Weisz L et al. (2003) Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumorassociated p53 mutants. Oncogene 22:5667-76
-
(2003)
Oncogene
, vol.22
, pp. 5667-5676
-
-
Zalcenstein, A.1
Stambolsky, P.2
Weisz, L.3
-
54
-
-
79959343390
-
Two-phase dynamics of p53 in the DNA damage response
-
Zhang XP, Liu F, Wang W (2011) Two-phase dynamics of p53 in the DNA damage response. Proc Natl Acad Sci USA 108:8990-5
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 8990-8995
-
-
Zhang, X.P.1
Liu, F.2
Wang, W.3
-
55
-
-
47649114399
-
Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression
-
Zschiedrich I, Hardeland U, Krones-Herzig A et al. (2008) Coactivator function of RIP140 for NFkappaB/RelA-dependent cytokine gene expression. Blood 112:264-76
-
(2008)
Blood
, vol.112
, pp. 264-276
-
-
Zschiedrich, I.1
Hardeland, U.2
Krones-Herzig, A.3
|