메뉴 건너뛰기




Volumn 32, Issue 11, 2012, Pages 4813-4822

Desensitization of NFκB for overcoming chemoresistance of pancreatic cancer cells to TNF-α or paclitaxel

Author keywords

Chemoresistance; Desensitization; Doxycycline; NF B; PANC 1 cells; Pancreatic cancer

Indexed keywords

DOXYCYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR P50; TUMOR NECROSIS FACTOR RECEPTOR P55; TUMOR NECROSIS FACTOR RECEPTOR P75; UNCLASSIFIED DRUG;

EID: 84872665123     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (34)
  • 2
    • 7044253530 scopus 로고    scopus 로고
    • Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: A prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors
    • Tran KT, Smeenk HG, van Eijck CH, Kazemier G, Hop WC, Greve JW, Terpstra OT, Zijlstra JA, Klinkert P and Jeekel H: Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors. Ann Surg 240: 738-745, 2004.
    • (2004) Ann Surg , vol.240 , pp. 738-745
    • Tran, K.T.1    Smeenk, H.G.2    Van Eijck, C.H.3    Kazemier, G.4    Hop, W.C.5    Greve, J.W.6    Terpstra, O.T.7    Zijlstra, J.A.8    Klinkert, P.9    Jeekel, H.10
  • 3
    • 43749098070 scopus 로고    scopus 로고
    • NF-kappaB and cancer-identifying targets and mechanisms
    • Naugler WE and Karin M: NF-kappaB and cancer-identifying targets and mechanisms. Curr Opin Genet Dev 18 : 19-26, 2008.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 19-26
    • Naugler, W.E.1    Karin, M.2
  • 4
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M: Nuclear factor-kappaB in cancer development and progression. Nature 441 : 431-436, 2006.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 6
    • 0038682199 scopus 로고    scopus 로고
    • Involvement of nuclear transcription factor-kappa B in low-dose doxorubicin-induced drug resistance of cervical carcinoma cells
    • Yeh PY, Chuang SE, Yeh KH, Song YC and Cheng AL: Involvement of nuclear transcription factor-kappa B in low-dose doxorubicin-induced drug resistance of cervical carcinoma cells. Biochemical pharmacology 66 : 25-33, 2003.
    • (2003) Biochemical Pharmacology , vol.66 , pp. 25-33
    • Yeh, P.Y.1    Chuang, S.E.2    Yeh, K.H.3    Song, Y.C.4    Cheng, A.L.5
  • 7
    • 84860436602 scopus 로고    scopus 로고
    • Advances in the understanding of mechanisms and therapeutic use of bortezomib
    • Mujtaba T and Dou QP: Advances in the understanding of mechanisms and therapeutic use of bortezomib. Discovery medicine 12: 471-480, 2011.
    • (2011) Discovery Medicine , vol.12 , pp. 471-480
    • Mujtaba, T.1    Dou, Q.P.2
  • 8
    • 0031001825 scopus 로고    scopus 로고
    • Stress response decreases NF-kappaB nuclear translocation and increases I-kappaBalpha expression in A549 cells
    • Wong HR, Ryan M and Wispe JR: Stress response decreases NF-kappaB nuclear translocation and increases I-kappaBalpha expression in A549 cells. The Journal of clinical investigation 99 : 2423-2428, 1997.
    • (1997) The Journal of Clinical Investigation , vol.99 , pp. 2423-2428
    • Wong, H.R.1    Ryan, M.2    Wispe, J.R.3
  • 9
    • 0030833417 scopus 로고    scopus 로고
    • Failure of a second X-ray dose to activate nuclear factor kappaB in normal rat astrocytes
    • Raju U, Lu R, Noel F, Gumin GJ and Tofilon PJ: Failure of a second X-ray dose to activate nuclear factor kappaB in normal rat astrocytes. J Biol Chem 272 : 24624-24630, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 24624-24630
    • Raju, U.1    Lu, R.2    Noel, F.3    Gumin, G.J.4    Tofilon, P.J.5
  • 13
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB
    • Wang CY, Cusack JC Jr., Liu R and Baldwin AS Jr.: Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB. Nat Med 5: 412-417, 1999.
    • (1999) Nat Med , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack Jr., J.C.2    Liu, R.3    Baldwin Jr., A.S.4
  • 14
    • 0029858387 scopus 로고    scopus 로고
    • TNF- And cancer therapy-induced apoptosis: Potentiation by inhibition of NFkappaB
    • Wang CY, Mayo MW and Baldwin AS, Jr.: TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NFkappaB. Science 274: 784-787, 1996.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.Y.1    Mayo, M.W.2    Baldwin Jr., A.S.3
  • 15
    • 0030613551 scopus 로고    scopus 로고
    • The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation
    • Zandi E, Rothwarf DM, Delhase M, Hayakawa M and Karin M: The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation. Cell 91: 243-252, 1997.
    • (1997) Cell , vol.91 , pp. 243-252
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5
  • 17
    • 0033979225 scopus 로고    scopus 로고
    • Docetaxel chemotherapy for pancreatic cancer: Do results support certainty? Italian Group for the Study of Gastrointestinal Tract Carcinomas
    • Graziano F and Cascinu S: Docetaxel chemotherapy for pancreatic cancer: Do results support certainty? Italian Group for the Study of Gastrointestinal Tract Carcinomas. J Clin Oncol 18: 445-446, 2000.
    • (2000) J Clin Oncol , vol.18 , pp. 445-446
    • Graziano, F.1    Cascinu, S.2
  • 20
    • 0035854769 scopus 로고    scopus 로고
    • Redox-sensitive transactivation of epidermal growth factor receptor by tumor necrosis factor confers the NF-kappa B activation
    • Hirota K, Murata M, Itoh T, Yodoi J and Fukuda K: Redox-sensitive transactivation of epidermal growth factor receptor by tumor necrosis factor confers the NF-kappa B activation. J Biol Chem 276 : 25953-25958, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 25953-25958
    • Hirota, K.1    Murata, M.2    Itoh, T.3    Yodoi, J.4    Fukuda, K.5
  • 22
    • 0032711015 scopus 로고    scopus 로고
    • Discovery of differentially expressed genes associated with paclitaxel resistance using cDNA array technology: Analysis of interleukin (IL) 6, IL-8, and monocyte chemotactic protein 1 in the paclitaxel-resistant phenotype
    • Duan Z, Feller AJ, Penson RT, Chabner BA and Seiden MV: Discovery of differentially expressed genes associated with paclitaxel resistance using cDNA array technology: analysis of interleukin (IL) 6, IL-8, and monocyte chemotactic protein 1 in the paclitaxel-resistant phenotype. Clin Cancer Res 5 : 3445-3453, 1999.
    • (1999) Clin Cancer Res , vol.5 , pp. 3445-3453
    • Duan, Z.1    Feller, A.J.2    Penson, R.T.3    Chabner, B.A.4    Seiden, M.V.5
  • 23
    • 0037091048 scopus 로고    scopus 로고
    • Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NF kappa B activation
    • Yeh PY, Chuang SE, Yeh KH, Song YC, Ea CK and Cheng AL: Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NF kappa B activation. Biochemical pharmacology 63: 1423-1430, 2002.
    • (2002) Biochemical Pharmacology , vol.63 , pp. 1423-1430
    • Yeh, P.Y.1    Chuang, S.E.2    Yeh, K.H.3    Song, Y.C.4    Ea, C.K.5    Cheng, A.L.6
  • 25
    • 0028985601 scopus 로고
    • Nuclear factor kappa B functions as a negative regulator for the rat androgen receptor gene and NF-kappa B activity increases during the age-dependent desensitization of the liver
    • Supakar PC, Jung MH, Song CS, Chatterjee B and Roy AK: Nuclear factor kappa B functions as a negative regulator for the rat androgen receptor gene and NF-kappa B activity increases during the age-dependent desensitization of the liver. J Biol Chem 270: 837-842, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 837-842
    • Supakar, P.C.1    Jung, M.H.2    Song, C.S.3    Chatterjee, B.4    Roy, A.K.5
  • 26
    • 0026566173 scopus 로고
    • Endotoxin tolerance: In vivo regulation of tumor necrosis factor and interleukin-1 synthesis is at the transcriptional level
    • Zuckerman SH and Evans GF: Endotoxin tolerance: in vivo regulation of tumor necrosis factor and interleukin-1 synthesis is at the transcriptional level. Cellular immunology 140 : 513-519, 1992.
    • (1992) Cellular Immunology , vol.140 , pp. 513-519
    • Zuckerman, S.H.1    Evans, G.F.2
  • 27
    • 0033857751 scopus 로고    scopus 로고
    • Lipopolysaccharide-triggered desensitization of TNF-alpha mRNA expression involves lack of phosphorylation of IkappaBalpha in a murine macrophage-like cell line, P388D1
    • Fujihara M, Wakamoto S, Ito T, Muroi M, Suzuki T, Ikeda H and Ikebuchi K: Lipopolysaccharide-triggered desensitization of TNF-alpha mRNA expression involves lack of phosphorylation of IkappaBalpha in a murine macrophage-like cell line, P388D1. Journal of leukocyte biology 68: 267-276, 2000.
    • (2000) Journal of Leukocyte Biology , vol.68 , pp. 267-276
    • Fujihara, M.1    Wakamoto, S.2    Ito, T.3    Muroi, M.4    Suzuki, T.5    Ikeda, H.6    Ikebuchi, K.7
  • 28
    • 0035139058 scopus 로고    scopus 로고
    • Paclitaxel-induced immune suppression is associated with NF-kappaB activation via conventional PKC isotypes in lipopolysaccharide-stimulated 70Z/3 pre-B lymphocyte tumor cells
    • Lee M and Jeon YJ: Paclitaxel-induced immune suppression is associated with NF-kappaB activation via conventional PKC isotypes in lipopolysaccharide- stimulated 70Z/3 pre-B lymphocyte tumor cells. Mol Pharmacol 59: 248-253, 2001.
    • (2001) Mol Pharmacol , vol.59 , pp. 248-253
    • Lee, M.1    Jeon, Y.J.2
  • 29
    • 0034820511 scopus 로고    scopus 로고
    • The p50-homodimer mechanism in tolerance to LPS
    • Ziegler-Heitbrock L: The p50-homodimer mechanism in tolerance to LPS. J Endotoxin Res 7: 219-222, 2001.
    • (2001) J Endotoxin Res , vol.7 , pp. 219-222
    • Ziegler-Heitbrock, L.1
  • 30
    • 0032896495 scopus 로고    scopus 로고
    • Enhancement of chemosensitivity and programmed cell death by tyrosine kinase inhibitors correlates with EGFR expression in non-small cell lung cancer cells
    • Lei W, Mayotte JE and Levitt ML: Enhancement of chemosensitivity and programmed cell death by tyrosine kinase inhibitors correlates with EGFR expression in non-small cell lung cancer cells. Anticancer Res 19: 221-228, 1999.
    • (1999) Anticancer Res , vol.19 , pp. 221-228
    • Lei, W.1    Mayotte, J.E.2    Levitt, M.L.3
  • 31
    • 0027293748 scopus 로고
    • Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness
    • Yamanaka Y, Friess H, Kobrin MS, Buchler M, Beger HG and Korc M: Coexpression of epidermal growth factor receptor and ligands in human pancreatic cancer is associated with enhanced tumor aggressiveness. Anticancer Res 13: 565-569, 1993.
    • (1993) Anticancer Res , vol.13 , pp. 565-569
    • Yamanaka, Y.1    Friess, H.2    Kobrin, M.S.3    Buchler, M.4    Beger, H.G.5    Korc, M.6
  • 32
    • 0035937845 scopus 로고    scopus 로고
    • The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NFkappaB)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome
    • Habib AA, Chatterjee S, Park SK, Ratan RR, Lefebvre S and Vartanian T: The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NFkappaB)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome. J Biol Chem 276: 8865-8874, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 8865-8874
    • Habib, A.A.1    Chatterjee, S.2    Park, S.K.3    Ratan, R.R.4    Lefebvre, S.5    Vartanian, T.6
  • 34
    • 0344549859 scopus 로고    scopus 로고
    • Regulation of RelA subcellular localization by a putative nuclear export signal and p50
    • Harhaj EW and Sun SC: Regulation of RelA subcellular localization by a putative nuclear export signal and p50. Mol Cell Biol 19: 7088-7095, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 7088-7095
    • Harhaj, E.W.1    Sun, S.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.