In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells

Science Translational Medicine

Volumn 7, Issue 273, 2015, Pages 273ra13-

  Biasco, Luca ^a   Scala, Serena ^a,b   Basso Ricci, Luca ^a   Dionisio, Francesca ^a   Baricordi, Cristina ^a   Calabria, Andrea ^a   Giannelli, Stefania ^a   Cieri, Nicoletta ^c   Barzaghi, Federica ^c   Pajno, Roberta ^c   Al Mousa, Hamoud ^d   Scarselli, Alessia ^e   Cancrini, Caterina ^e   Bordignon, Claudio ^b   Roncarolo, Maria Grazia ^a,b   Montini, Eugenio ^a   Bonini, Chiara ^c   Aiuti, Alessandro ^c,e  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^e UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

RETROVIRUS VECTOR;

ADULT; AGE; ARTICLE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL ENGINEERING; CELL FATE; CELL SURVIVAL; CELL TRACKING; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DNA MODIFICATION; EX VIVO STUDY; GENE THERAPY; HEMATOPOIETIC STEM CELL; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOTHERAPY; IN VIVO STUDY; INFUSION; LYMPHOCYTE CLONE; MEMORY T LYMPHOCYTE; MEMORY T LYMPHOCYTE STEM CELL; RETROVIRUS; STEM CELL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

EID: 84922661546     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3010314     Document Type: Article

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