Whole transcriptome characterization of aberrant splicing events induced by lentiviral vector integrations

Journal of Clinical Investigation

Volumn 122, Issue 5, 2012, Pages 1667-1676

  Cesana, Daniela ^a   Sgualdino, Jacopo ^a,b   Rudilosso, Laura ^a   Merella, Stefania ^a   Naldini, Luigi ^a,b   Montini, Eugenio ^a  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; COMPLEMENTARY DNA; LENTIVIRUS VECTOR; MESSENGER RNA; TRANSCRIPTOME;

ARTICLE; CELL FUSION; GENE; GENE AMPLIFICATION; GENE FUSION; GENE SEQUENCE; HEMATOPOIETIC STEM CELL; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; LONG TERMINAL REPEAT; LYMPHOBLASTOID CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROVIRUS; SPLICING DEFECT; VIRUS GENOME;

ALTERNATIVE SPLICING; BASE SEQUENCE; CELLS, CULTURED; GENE EXPRESSION PROFILING; GENES, ESSENTIAL; HEMATOPOIETIC STEM CELLS; HUMANS; LENTIVIRUS; LENTIVIRUS INFECTIONS; MUTAGENESIS, INSERTIONAL; MUTANT CHIMERIC PROTEINS; POLYMERASE CHAIN REACTION; PRIMARY CELL CULTURE; PROTEIN ISOFORMS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TERMINAL REPEAT SEQUENCES; TRANSCRIPTOME; VIRUS INTEGRATION;

EID: 84860555634     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI62189     Document Type: Article

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