Invasive breast cancer reprograms early myeloid differentiation in the bone marrow to generate immunosuppressive neutrophils

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 6, 2015, Pages E566-E575

  Casbon, Amy Jo ^a   Reynau, Damien ^a   Park, Chanhyuk ^a   Khu, Emily ^a   Gan, Dennis D ^a   Schepers, Koen ^a   Passegué, Emmanuelle ^a   Werb, Zena ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cancer; Hematopoiesis; Immunology; Myeloid derived suppressor cells; Stem cell biology

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; BROXURIDINE; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR;

ANEMIA; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MARROW CELL; BREAST CANCER; CANCER STAGING; CARCINOGENESIS; CELL ACTIVATION; CELL DIFFERENTIATION; CELL EXPANSION; CELL POPULATION; CONTROLLED STUDY; ERYTHROPOIESIS; FEMALE; HEMATOPOIESIS; IN VIVO STUDY; MOUSE; MYELOID PROGENITOR CELL; NEUTROPHIL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; SPLENOMEGALY; STEM CELL; T LYMPHOCYTE; TUMOR GROWTH; ANIMAL; BLOOD; BREAST TUMOR; C57BL MOUSE; FLOW CYTOMETRY; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL LINE; TUMOR INVASION;

MUS;

ANIMALS; BREAST NEOPLASMS; BROMODEOXYURIDINE; CELL LINE, TUMOR; FEMALE; FLOW CYTOMETRY; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; IMMUNE TOLERANCE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELLS; NEOPLASM INVASIVENESS; NEUTROPHILS; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR;

EID: 84922660501     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1424927112     Document Type: Article

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