메뉴 건너뛰기




Volumn 28, Issue 9, 2014, Pages 1851-1860

G-CSF regulates hematopoietic stem cell activity, in part, through activation of Toll-like receptor signaling

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CIPROFLOXACIN; MYELOID DIFFERENTIATION FACTOR 88; POLYMYXIN B; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 13; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 6; UNCLASSIFIED DRUG;

EID: 84908288477     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2014.68     Document Type: Article
Times cited : (113)

References (50)
  • 1
    • 79751536458 scopus 로고    scopus 로고
    • Inflammatory signals regulate hematopoietic stem cells
    • Baldridge MT, King KY, Goodell MA. Inflammatory signals regulate hematopoietic stem cells. Trends Immunol. 2011; 32: 57-65
    • (2011) Trends Immunol , vol.32 , pp. 57-65
    • Baldridge, M.T.1    King, K.Y.2    Goodell, M.A.3
  • 2
    • 80053133049 scopus 로고    scopus 로고
    • Inflammatory modulation of hscs: Viewing the hsc as a foundation for the immune response
    • King KY, Goodell MA. Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol. 2011; 11: 685-692
    • (2011) Nat Rev Immunol , vol.11 , pp. 685-692
    • King, K.Y.1    Goodell, M.A.2
  • 3
    • 84155172567 scopus 로고    scopus 로고
    • Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells
    • Boiko JR, Borghesi L. Hematopoiesis sculpted by pathogens: Toll-like receptors and inflammatory mediators directly activate stem cells. Cytokine. 2012; 57: 1-8
    • (2012) Cytokine , vol.57 , pp. 1-8
    • Boiko, J.R.1    Borghesi, L.2
  • 4
    • 67149091317 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type i interferon-dependent exhaustion
    • Sato T, Onai N, Yoshihara H, Arai F, Suda T, Ohteki T. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat Med. 2009; 15: 696-700
    • (2009) Nat Med , vol.15 , pp. 696-700
    • Sato, T.1    Onai, N.2    Yoshihara, H.3    Arai, F.4    Suda, T.5    Ohteki, T.6
  • 6
    • 79960810509 scopus 로고    scopus 로고
    • Irgm1 protects hematopoietic stem cells by negative regulation of ifn signaling
    • King KY, Baldridge MT, Weksberg DC, Chambers SM, Lukov GL, Wu S., et al. Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood. 2011; 118: 1525-1533
    • (2011) Blood , vol.118 , pp. 1525-1533
    • King, K.Y.1    Baldridge, M.T.2    Weksberg, D.C.3    Chambers, S.M.4    Lukov, G.L.5    Wu, S.6
  • 7
    • 75349102361 scopus 로고    scopus 로고
    • Brief report: Interferon-gamma induces expansion of lin(-)sca-1(+)c-kit(+) cells
    • Zhao X, Ren G, Liang L, Ai PZ, Zheng B, Tischfield JA., et al. Brief report: interferon-gamma induces expansion of Lin(-)Sca-1(+)C-Kit(+) Cells. Stem Cells. 2010; 28: 122-126
    • (2010) Stem Cells , vol.28 , pp. 122-126
    • Zhao, X.1    Ren, G.2    Liang, L.3    Ai, P.Z.4    Zheng, B.5    Tischfield, J.A.6
  • 9
    • 0030745556 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor (g-csf) serum levels in surgical intensive care patients
    • Gross-Weege W, Dumon K, Dahmen A, Schneider EM, Roher HD. Granulocyte colony-stimulating factor (G-CSF) serum levels in surgical intensive care patients. Infection. 1997; 25: 213-216
    • (1997) Infection , vol.25 , pp. 213-216
    • Gross-Weege, W.1    Dumon, K.2    Dahmen, A.3    Schneider, E.M.4    Roher, H.D.5
  • 10
    • 44449087304 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and 'emergency' hematopoiesis
    • Panopoulos AD, Watowich SS. Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis. Cytokine. 2008; 42: 277-288
    • (2008) Cytokine , vol.42 , pp. 277-288
    • Panopoulos, A.D.1    Watowich, S.S.2
  • 12
    • 0242663403 scopus 로고    scopus 로고
    • Pivotal role of granulocyte colonystimulating factor in the development of progenitors in the common myeloid pathway
    • Richards MK, Liu F, Iwasaki H, Akashi K, Link DC. Pivotal role of granulocyte colonystimulating factor in the development of progenitors in the common myeloid pathway. Blood. 2003; 102: 3562-3568
    • (2003) Blood , vol.102 , pp. 3562-3568
    • Richards, M.K.1    Liu, F.2    Iwasaki, H.3    Akashi, K.4    Link, D.C.5
  • 13
    • 0028822673 scopus 로고
    • The kinetics of murine hematopoietic stem cells in vivo in response to prolonged increased mature blood cell production induced by granulocyte colony-stimulating factor
    • de Haan G, Dontje B, Engel C, Loeffler M, Nijhof W. The kinetics of murine hematopoietic stem cells in vivo in response to prolonged increased mature blood cell production induced by granulocyte colony-stimulating factor. Blood. 1995; 86: 2986-2992
    • (1995) Blood , vol.86 , pp. 2986-2992
    • De Haan, G.1    Dontje, B.2    Engel, C.3    Loeffler, M.4    Nijhof, W.5
  • 14
    • 0029957124 scopus 로고    scopus 로고
    • Bone marrow collected 14 days after in vivo administration of granulocyte colony-stimulating factor and stem cell factor to mice has 10-fold more repopulating ability than untreated bone marrow
    • Bodine DM, Seidel NE, Orlic D. Bone marrow collected 14 days after in vivo administration of granulocyte colony-stimulating factor and stem cell factor to mice has 10-fold more repopulating ability than untreated bone marrow. Blood. 1996; 88: 89-97
    • (1996) Blood , vol.88 , pp. 89-97
    • Bodine, D.M.1    Seidel, N.E.2    Orlic, D.3
  • 15
    • 84863776051 scopus 로고    scopus 로고
    • Hematopoietic stem cell mobilizing agents g-csf, cyclophosphamide or amd3100 have distinct mechanisms of action on bone marrow hsc niches and bone formation
    • Winkler IG, Pettit AR, Raggatt LJ, Jacobsen RN, Forristal CE, Barbier V., et al. Hematopoietic stem cell mobilizing agents G-CSF, cyclophosphamide or AMD3100 have distinct mechanisms of action on bone marrow HSC niches and bone formation. Leukemia. 2012; 26: 1594-1601
    • (2012) Leukemia , vol.26 , pp. 1594-1601
    • Winkler, I.G.1    Pettit, A.R.2    Raggatt, L.J.3    Jacobsen, R.N.4    Forristal, C.E.5    Barbier, V.6
  • 16
    • 27644517442 scopus 로고    scopus 로고
    • G-csf potently inhibits osteoblast activity and cxcl12 mRNA expression in the bone marrow
    • Semerad CL, Christopher MJ, Liu F, Short B, Simmons PJ, Winkler I., et al. G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood. 2005; 106: 3020-3027
    • (2005) Blood , vol.106 , pp. 3020-3027
    • Semerad, C.L.1    Christopher, M.J.2    Liu, F.3    Short, B.4    Simmons, P.J.5    Winkler, I.6
  • 17
    • 54249107906 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor induces osteoblast apoptosis and inhibits osteoblast differentiation
    • Christopher MJ, Link DC. Granulocyte colony-stimulating factor induces osteoblast apoptosis and inhibits osteoblast differentiation. J Bone Miner Res. 2008; 23: 1765-1774
    • (2008) J Bone Miner Res , vol.23 , pp. 1765-1774
    • Christopher, M.J.1    Link, D.C.2
  • 18
    • 0037237648 scopus 로고    scopus 로고
    • Disruption of the cxcr4/cxcl12 chemotactic interaction during hematopoietic stem cell mobilization induced by gcsf or cyclophosphamide
    • Levesque JP, Hendy J, Takamatsu Y, Simmons PJ, Bendall LJ. Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J Clin Invest. 2003; 111: 187-196
    • (2003) J Clin Invest , vol.111 , pp. 187-196
    • Levesque, J.P.1    Hendy, J.2    Takamatsu, Y.3    Simmons, P.J.4    Bendall, L.J.5
  • 19
    • 0036302147 scopus 로고    scopus 로고
    • G-csf induces stem cell mobilization by decreasing bone marrow sdf-1 and up-regulating cxcr4
    • Petit I, Szyper-Kravitz M, Nagler A, Lahav M, Peled A, Habler L., et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol. 2002; 3: 687-694
    • (2002) Nat Immunol , vol.3 , pp. 687-694
    • Petit, I.1    Szyper-Kravitz, M.2    Nagler, A.3    Lahav, M.4    Peled, A.5    Habler, L.6
  • 20
    • 0027893247 scopus 로고
    • Primitive hemopoietic stem cells: Direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations
    • Harrison DE, Jordan CT, Zhong RK, Astle CM. Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations. Exp Hematol. 1993; 21: 206-219
    • (1993) Exp Hematol , vol.21 , pp. 206-219
    • Harrison, D.E.1    Jordan, C.T.2    Zhong, R.K.3    Astle, C.M.4
  • 21
    • 0027185511 scopus 로고
    • Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells
    • Fleming WH, Alpern EJ, Uchida N, Ikuta K, Spangrude GJ, Weissman IL. Functional heterogeneity is associated with the cell cycle status of murine hematopoietic stem cells. J Cell Biol. 1993; 122: 897-902
    • (1993) J Cell Biol , vol.122 , pp. 897-902
    • Fleming, W.H.1    Alpern, E.J.2    Uchida, N.3    Ikuta, K.4    Spangrude, G.J.5    Weissman, I.L.6
  • 22
    • 0034672254 scopus 로고    scopus 로고
    • Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their s/g(2)/m transit and do not reenter g(0
    • Glimm H, Oh IH, Eaves CJ. Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0). Blood. 2000; 96: 4185-4193
    • (2000) Blood , vol.96 , pp. 4185-4193
    • Glimm, H.1    Oh, I.H.2    Eaves, C.J.3
  • 23
    • 28544436371 scopus 로고    scopus 로고
    • Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates
    • Passegue E, Wagers AJ, Giuriato S, Anderson WC, Weissman IL. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates. J Exp Med. 2005; 202: 1599-1611
    • (2005) J Exp Med , vol.202 , pp. 1599-1611
    • Passegue, E.1    Wagers, A.J.2    Giuriato, S.3    Anderson, W.C.4    Weissman, I.L.5
  • 24
    • 31544451592 scopus 로고    scopus 로고
    • Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocytecolony stimulating factor in vitro promotes their elimination by imatinib mesylate
    • Jorgensen HG, Copland M, Allan EK, Jiang X, Eaves A, Eaves C., et al. Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocytecolony stimulating factor in vitro promotes their elimination by imatinib mesylate. Clinical Cancer Res. 2006; 12: 626-633
    • (2006) Clinical Cancer Res , vol.12 , pp. 626-633
    • Jorgensen, H.G.1    Copland, M.2    Allan, E.K.3    Jiang, X.4    Eaves, A.5    Eaves, C.6
  • 25
    • 0031059252 scopus 로고    scopus 로고
    • Cyclophosphamide/granulocyte colonystimulating factor induces hematopoietic stem cells to proliferate prior to mobilization
    • Morrison SJ, Wright DE, Weissman IL. Cyclophosphamide/granulocyte colonystimulating factor induces hematopoietic stem cells to proliferate prior to mobilization. Proc Natl Acad Sci USA. 1997; 94: 1908-1913
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1908-1913
    • Morrison, S.J.1    Wright, D.E.2    Weissman, I.L.3
  • 26
    • 56549128268 scopus 로고    scopus 로고
    • Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
    • Wilson A, Laurenti E, Oser G, van der Wath RC, Blanco-Bose W, Jaworski M., et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell. 2008; 135: 1118-1129
    • (2008) Cell , vol.135 , pp. 1118-1129
    • Wilson, A.1    Laurenti, E.2    Oser, G.3    Van Der Wath, R.C.4    Blanco-Bose, W.5    Jaworski, M.6
  • 27
    • 76249093445 scopus 로고    scopus 로고
    • Siglec-e is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit tlr-driven cytokine production
    • Boyd CR, Orr SJ, Spence S, Burrows JF, Elliott J, Carroll HP., et al. Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production. J Immunol. 2009; 183: 7703-7709
    • (2009) J Immunol , vol.183 , pp. 7703-7709
    • Boyd, C.R.1    Orr, S.J.2    Spence, S.3    Burrows, J.F.4    Elliott, J.5    Carroll, H.P.6
  • 29
    • 79251561568 scopus 로고    scopus 로고
    • Macrophage activation and differentiation signals regulate schlafen-4 gene expression: Evidence for schlafen-4 as a modulator of myelopoiesis
    • van Zuylen WJ, Garceau V, Idris A, Schroder K, Irvine KM, Lattin JE., et al. Macrophage activation and differentiation signals regulate schlafen-4 gene expression: evidence for Schlafen-4 as a modulator of myelopoiesis. PLoS One. 2011; 6: e15723
    • (2011) PLoS One , vol.6 , pp. e15723
    • Van Zuylen, W.J.1    Garceau, V.2    Idris, A.3    Schroder, K.4    Irvine, K.M.5    Lattin, J.E.6
  • 30
    • 84937949371 scopus 로고    scopus 로고
    • Gene expression of factors related to the immune reaction in response to intramammary Escherichia coli lipopolysaccharide challenge
    • Bruckmaier RM. Gene expression of factors related to the immune reaction in response to intramammary Escherichia coli lipopolysaccharide challenge. J Dairy Res. 2005; 8: 131-141
    • (2005) J Dairy Res , vol.8 , pp. 131-141
    • Bruckmaier, R.M.1
  • 31
    • 20444371313 scopus 로고    scopus 로고
    • Characterization of the infectionresponsive bovine lactoferrin promoter
    • Zheng J, Ather JL, Sonstegard TS, Kerr DE. Characterization of the infectionresponsive bovine lactoferrin promoter. Gene. 2005; 353: 107-117
    • (2005) Gene , vol.353 , pp. 107-117
    • Zheng, J.1    Ather, J.L.2    Sonstegard, T.S.3    Kerr, D.E.4
  • 32
    • 0037200031 scopus 로고    scopus 로고
    • A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-Activated protein kinase
    • Fessler MB, Malcolm KC, Duncan MW, Worthen GS. A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-Activated protein kinase. J Biol Chem. 2002; 277: 31291-31302
    • (2002) J Biol Chem , vol.277 , pp. 31291-31302
    • Fessler, M.B.1    Malcolm, K.C.2    Duncan, M.W.3    Worthen, G.S.4
  • 33
    • 33744978765 scopus 로고    scopus 로고
    • Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment
    • Nagai Y, Garrett KP, Ohta S, Bahrun U, Kouro T, Akira S., et al. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity. 2006; 24: 801-812
    • (2006) Immunity , vol.24 , pp. 801-812
    • Nagai, Y.1    Garrett, K.P.2    Ohta, S.3    Bahrun, U.4    Kouro, T.5    Akira, S.6
  • 34
    • 84873257690 scopus 로고    scopus 로고
    • Chronic tlr signaling impairs the long-Term repopulating potential of hematopoietic stem cells of wild type but not id1 deficient mice
    • Zhao Y, Ling F, Wang HC, Sun XH. Chronic TLR signaling impairs the long-Term repopulating potential of hematopoietic stem cells of wild type but not id1 deficient mice. PLoS One. 2013; 8: e55552
    • (2013) PLoS One , vol.8 , pp. e55552
    • Zhao, Y.1    Ling, F.2    Wang, H.C.3    Sun, X.H.4
  • 35
    • 77950389067 scopus 로고    scopus 로고
    • Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis
    • Rodriguez S, Chora A, Goumnerov B, Mumaw C, Goebel WS, Fernandez L., et al. Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis. Blood. 2009; 114: 4064-4076
    • (2009) Blood , vol.114 , pp. 4064-4076
    • Rodriguez, S.1    Chora, A.2    Goumnerov, B.3    Mumaw, C.4    Goebel, W.S.5    Fernandez, L.6
  • 36
    • 34948878649 scopus 로고    scopus 로고
    • Id1 but not id3, directs long-Term repopulating hematopoietic stem-cell maintenance
    • Perry SS, Zhao Y, Nie L, Cochrane SW, Huang Z, Sun XH. Id1 but not Id3, directs long-Term repopulating hematopoietic stem-cell maintenance. Blood. 2007; 110: 2351-2360
    • (2007) Blood , vol.110 , pp. 2351-2360
    • Perry, S.S.1    Zhao, Y.2    Nie, L.3    Cochrane, S.W.4    Huang, Z.5    Sun, X.H.6
  • 37
    • 77955864182 scopus 로고    scopus 로고
    • Functional diversity of stem and progenitor cells with b-lymphopoietic potential
    • Ichii M, Shimazu T, Welner RS, Garrett KP, Zhang Q, Esplin BL., et al. Functional diversity of stem and progenitor cells with B-lymphopoietic potential. Immunol Rev. 2010; 237: 10-21
    • (2010) Immunol Rev , vol.237 , pp. 10-21
    • Ichii, M.1    Shimazu, T.2    Welner, R.S.3    Garrett, K.P.4    Zhang, Q.5    Esplin, B.L.6
  • 38
    • 0347597743 scopus 로고    scopus 로고
    • Reduced stem cell mobilization in mice receiving antibiotic modulation of the intestinal flora: Involvement of endotoxins as cofactors in mobilization
    • Velders GA, van Os R, Hagoort H, Verzaal P, Guiot HF, Lindley IJ., et al. Reduced stem cell mobilization in mice receiving antibiotic modulation of the intestinal flora: involvement of endotoxins as cofactors in mobilization. Blood. 2004; 103: 340-346
    • (2004) Blood , vol.103 , pp. 340-346
    • Velders, G.A.1    Van Os, R.2    Hagoort, H.3    Verzaal, P.4    Guiot, H.F.5    Lindley, I.J.6
  • 39
    • 84859212810 scopus 로고    scopus 로고
    • Granulocyte colony stimulating factor expands hematopoietic stem cells within the central but not endosteal bone marrow region
    • Grassinger J, Williams B, Olsen GH, Haylock DN, Nilsson SK. Granulocyte colony stimulating factor expands hematopoietic stem cells within the central but not endosteal bone marrow region. Cytokine. 2012; 58: 218-225
    • (2012) Cytokine , vol.58 , pp. 218-225
    • Grassinger, J.1    Williams, B.2    Olsen, G.H.3    Haylock, D.N.4    Nilsson, S.K.5
  • 40
    • 0035885005 scopus 로고    scopus 로고
    • Signaling lymphocytic activation molecule is expressed on cd40 ligand-Activated dendritic cells and directly augments production of inflammatory cytokines
    • Bleharski JR, Niazi KR, Sieling PA, Cheng G, Modlin RL. Signaling lymphocytic activation molecule is expressed on CD40 ligand-Activated dendritic cells and directly augments production of inflammatory cytokines. J Immunol. 2001; 167: 3174-3181
    • (2001) J Immunol , vol.167 , pp. 3174-3181
    • Bleharski, J.R.1    Niazi, K.R.2    Sieling, P.A.3    Cheng, G.4    Modlin, R.L.5
  • 41
    • 2942512621 scopus 로고    scopus 로고
    • Distinct responses of monocytes to toll-like receptor ligands and inflammatory cytokines
    • Farina C, Theil D, Semlinger B, Hohlfeld R, Meinl E. Distinct responses of monocytes to Toll-like receptor ligands and inflammatory cytokines. Int Immunol. 2004; 16: 799-809
    • (2004) Int Immunol , vol.16 , pp. 799-809
    • Farina, C.1    Theil, D.2    Semlinger, B.3    Hohlfeld, R.4    Meinl, E.5
  • 42
    • 0035881677 scopus 로고    scopus 로고
    • Signaling lymphocytic activation molecule is expressed on mature cd83+ dendritic cells and is up-regulated by il-1 beta
    • Kruse M, Meinl E, Henning G, Kuhnt C, Berchtold S, Berger T., et al. Signaling lymphocytic activation molecule is expressed on mature CD83+ dendritic cells and is up-regulated by IL-1 beta. J Immunol. 2001; 167: 1989-1995
    • (2001) J Immunol , vol.167 , pp. 1989-1995
    • Kruse, M.1    Meinl, E.2    Henning, G.3    Kuhnt, C.4    Berchtold, S.5    Berger, T.6
  • 43
    • 0032857031 scopus 로고    scopus 로고
    • Reversible expression of cd34 by murine hematopoietic stem cells
    • Sato T, Laver JH, Ogawa M. Reversible expression of CD34 by murine hematopoietic stem cells. Blood. 1999; 94: 2548-2554
    • (1999) Blood , vol.94 , pp. 2548-2554
    • Sato, T.1    Laver, J.H.2    Ogawa, M.3
  • 44
    • 0034284343 scopus 로고    scopus 로고
    • Cd34 expression by murine hematopoietic stem cells mobilized by granulocyte colony-stimulating factor
    • Tajima F, Sato T, Laver JH, Ogawa M. CD34 expression by murine hematopoietic stem cells mobilized by granulocyte colony-stimulating factor. Blood. 2000; 96: 1989-1993
    • (2000) Blood , vol.96 , pp. 1989-1993
    • Tajima, F.1    Sato, T.2    Laver, J.H.3    Ogawa, M.4
  • 45
    • 79951698622 scopus 로고    scopus 로고
    • Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation
    • Takizawa H, Regoes RR, Boddupalli CS, Bonhoeffer S, Manz MG. Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation. J Exp Med. 2011; 208: 273-284
    • (2011) J Exp Med , vol.208 , pp. 273-284
    • Takizawa, H.1    Regoes, R.R.2    Boddupalli, C.S.3    Bonhoeffer, S.4    Manz, M.G.5
  • 46
    • 84862865733 scopus 로고    scopus 로고
    • Direct toll-like receptor-mediated stimulation of hematopoietic stem and progenitor cells occurs in vivo and promotes differentiation toward macrophages
    • Megias J, Yanez A, Moriano S, O'Connor JE, Gozalbo D, Gil ML. Direct Toll-like receptor-mediated stimulation of hematopoietic stem and progenitor cells occurs in vivo and promotes differentiation toward macrophages. Stem Cells. 2012; 30: 1486-1495
    • (2012) Stem Cells , vol.30 , pp. 1486-1495
    • Megias, J.1    Yanez, A.2    Moriano, S.3    O'Connor, J.E.4    Gozalbo, D.5    Gil, M.L.6
  • 47
    • 84876913132 scopus 로고    scopus 로고
    • Role of the gut microbiota in immunity and inflammatory disease
    • Kamada N, Seo SU, Chen GY, Nunez G. Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol. 2013; 13: 321-335
    • (2013) Nat Rev Immunol , vol.13 , pp. 321-335
    • Kamada, N.1    Seo, S.U.2    Chen, G.Y.3    Nunez, G.4
  • 48
    • 39649088491 scopus 로고    scopus 로고
    • A prospective study of g-csf primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: A pediatric blood and marrow transplant consortium (pbmtc) study
    • Frangoul H, Nemecek ER, Billheimer D, Pulsipher MA, Khan S, Woolfrey A., et al. A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study. Blood. 2007; 110: 4584-4587
    • (2007) Blood , vol.110 , pp. 4584-4587
    • Frangoul, H.1    Nemecek, E.R.2    Billheimer, D.3    Pulsipher, M.A.4    Khan, S.5    Woolfrey, A.6
  • 49
    • 79551707003 scopus 로고    scopus 로고
    • Use of g-csf-stimulated marrow in allogeneic hematopoietic stem cell transplantation settings: A comprehensive review
    • Chang YJ, Huang XJ. Use of G-CSF-stimulated marrow in allogeneic hematopoietic stem cell transplantation settings: a comprehensive review. Clin Transplant. 2011; 25: 13-23
    • (2011) Clin Transplant , vol.25 , pp. 13-23
    • Chang, Y.J.1    Huang, X.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.