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Volumn 211, Issue 2, 2014, Pages 245-262

Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; APOPTOSIS; BONE MARROW; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SURVIVAL; FEMALE; G0 PHASE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; INTERFERON TYPE I; MALE; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84893810137     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131043     Document Type: Article
Times cited : (236)

References (43)
  • 1
    • 84887527463 scopus 로고    scopus 로고
    • Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells
    • (Epub ahead of print)
    • Bakker, S.T., and E. Passegué. 2013. Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells. Exp. Hematol. 41:915-923 (Epub ahead of print). http://dx.doi.org/10.1016/j.exphem.2013.09.007
    • (2013) Exp. Hematol. , vol.41 , pp. 915-923
    • Bakker, S.T.1    Passegué, E.2
  • 2
    • 77953462161 scopus 로고    scopus 로고
    • Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection
    • Baldridge, M.T., K.Y. King, N.C. Boles, D.C. Weksberg, and M.A. Goodell. 2010. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature. 465:793-797. http://dx.doi .org/10.1038/nature09135
    • (2010) Nature. , vol.465 , pp. 793-797
    • Baldridge, M.T.1    King, K.Y.2    Boles, N.C.3    Weksberg, D.C.4    Goodell, M.A.5
  • 3
    • 84877607466 scopus 로고    scopus 로고
    • TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy
    • Brenet, F., P. Kermani, R. Spektor, S. Rafii, and J.M. Scandura. 2013. TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy. J. Exp. Med. 210:623-639. http://dx.doi.org/10.1084/jem.20121610
    • (2013) J. Exp. Med. , vol.210 , pp. 623-639
    • Brenet, F.1    Kermani, P.2    Spektor, R.3    Rafii, S.4    Scandura, J.M.5
  • 4
    • 0038152845 scopus 로고    scopus 로고
    • Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
    • Castrillon, D.H., L. Miao, R. Kollipara, J.W. Horner, and R.A. DePinho. 2003. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science. 301:215-218. http://dx.doi.org/10.1126/ science.1086336
    • (2003) Science. , vol.301 , pp. 215-218
    • Castrillon, D.H.1    Miao, L.2    Kollipara, R.3    Horner, J.W.4    DePinho, R.A.5
  • 5
    • 75549090275 scopus 로고    scopus 로고
    • mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells
    • Chen, C., Y. Liu, Y. Liu, and P. Zheng. 2009. mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells. Sci. Signal. 2:ra75.
    • (2009) Sci. Signal. , vol.2
    • Chen, C.1    Liu, Y.2    Liu, Y.3    Zheng, P.4
  • 6
    • 80054709328 scopus 로고    scopus 로고
    • The role of cytokines in the pathogenesis and treatment of systemic lupus erythematosus
    • Davis, L.S., J. Hutcheson, and C. Mohan. 2011. The role of cytokines in the pathogenesis and treatment of systemic lupus erythematosus. J. Interferon Cytokine Res. 31:781-789. http://dx.doi.org/10.1089/jir.2011.0047
    • (2011) J. Interferon Cytokine Res. , vol.31 , pp. 781-789
    • Davis, L.S.1    Hutcheson, J.2    Mohan, C.3
  • 7
    • 84879722412 scopus 로고    scopus 로고
    • Interferon-γ impairs proliferation of hematopoietic stem cells in mice
    • de Bruin, A.M., O. Demirel, B. Hooibrink, C.H. Brandts, and M.A. Nolte. 2013. Interferon-γ impairs proliferation of hematopoietic stem cells in mice. Blood. 121:3578-3585. http://dx.doi.org/10.1182/blood-2012-05-432906
    • (2013) Blood. , vol.121 , pp. 3578-3585
    • de Bruin, A.M.1    Demirel, O.2    Hooibrink, B.3    Brandts, C.H.4    Nolte, M.A.5
  • 8
    • 0026561121 scopus 로고
    • Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
    • Donehower, L.A., M. Harvey, B.L. Slagle, M.J. McArthur, C.A. Montgomery Jr., J.S. Butel, and A. Bradley. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature. 356:215-221. http://dx.doi.org/10.1038/356215a0
    • (1992) Nature. , vol.356 , pp. 215-221
    • Donehower, L.A.1    Harvey, M.2    Slagle, B.L.3    McArthur, M.J.4    Montgomery, C.A.5    Butel, J.S.6    Bradley, A.7
  • 9
    • 0022453855 scopus 로고
    • Interferon-α/β enhances the expression of Ly-6 antigens on T cells in vivo and in vitro
    • Dumont, F.J., and L.Z. Coker. 1986. Interferon-α/β enhances the expression of Ly-6 antigens on T cells in vivo and in vitro. Eur. J. Immunol. 16:735-740. http://dx.doi.org/10.1002/eji.1830160704
    • (1986) Eur. J. Immunol. , vol.16 , pp. 735-740
    • Dumont, F.J.1    Coker, L.Z.2
  • 11
    • 37549048915 scopus 로고    scopus 로고
    • The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation
    • Feng, C.G., D.C. Weksberg, G.A. Taylor, A. Sher, and M.A. Goodell. 2008. The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. Cell Stem Cell. 2:83-89. http://dx.doi.org/10 .1016/j.stem.2007.10.007
    • (2008) Cell Stem Cell. , vol.2 , pp. 83-89
    • Feng, C.G.1    Weksberg, D.C.2    Taylor, G.A.3    Sher, A.4    Goodell, M.A.5
  • 14
    • 84861793605 scopus 로고    scopus 로고
    • Hematological features of pediatric systemic lupus erythematosus: suggesting management strategies in children
    • Gokce, M., Y. Bilginer, N. Besbas, F. Ozaltin, M. Cetin, F. Gumruk, and S. Ozen. 2012. Hematological features of pediatric systemic lupus erythematosus: suggesting management strategies in children. Lupus. 21:878-884. http://dx.doi.org/10.1177/0961203312443721
    • (2012) Lupus. , vol.21 , pp. 878-884
    • Gokce, M.1    Bilginer, Y.2    Besbas, N.3    Ozaltin, F.4    Cetin, M.5    Gumruk, F.6    Ozen, S.7
  • 15
    • 57849136005 scopus 로고    scopus 로고
    • ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
    • Hartner, J.C., C.R. Walkley, J. Lu, and S.H. Orkin. 2009. ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling. Nat. Immunol. 10:109-115. http://dx.doi.org/10.1038/ni.1680
    • (2009) Nat. Immunol. , vol.10 , pp. 109-115
    • Hartner, J.C.1    Walkley, C.R.2    Lu, J.3    Orkin, S.H.4
  • 16
    • 85040737071 scopus 로고    scopus 로고
    • Aplastic anemia associated with interferon alpha 2a in a patient with chronic hepatitis C virus infection: a case report
    • Ioannou, S., G. Hatzis, I. Vlahadami, and M. Voulgarelis. 2010. Aplastic anemia associated with interferon alpha 2a in a patient with chronic hepatitis C virus infection: a case report. J. Med. Case Reports. 4:268. http://dx.doi.org/10.1186/1752-1947-4-268
    • (2010) J. Med. Case Reports. , vol.4 , pp. 268
    • Ioannou, S.1    Hatzis, G.2    Vlahadami, I.3    Voulgarelis, M.4
  • 17
    • 79955947379 scopus 로고    scopus 로고
    • The renaissance of interferon therapy for the treatment of myeloid malignancies
    • Kiladjian, J.J., R.A. Mesa, and R. Hoffman. 2011. The renaissance of interferon therapy for the treatment of myeloid malignancies. Blood. 117:4706-4715. http://dx.doi.org/10.1182/blood-2010-08-258772
    • (2011) Blood. , vol.117 , pp. 4706-4715
    • Kiladjian, J.J.1    Mesa, R.A.2    Hoffman, R.3
  • 20
    • 80053296176 scopus 로고    scopus 로고
    • CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway
    • Lin, K.K., L. Rossi, N.C. Boles, B.E. Hall, T.C. George, and M.A. Goodell. 2011. CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway. PLoS Biol. 9:e1001148. http://dx.doi.org/10.1371/ journal.pbio.1001148
    • (2011) PLoS Biol. , vol.9
    • Lin, K.K.1    Rossi, L.2    Boles, N.C.3    Hall, B.E.4    George, T.C.5    Goodell, M.A.6
  • 22
    • 84879728130 scopus 로고    scopus 로고
    • Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera
    • Mullally, A., C. Bruedigam, L. Poveromo, F.H. Heidel, A. Purdon, T. Vu, R. Austin, D. Heckl, L.J. Breyfogle, C.P. Kuhn, et al. 2013. Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera. Blood. 121:3692-3702. http://dx.doi.org/10.1182/blood-2012-05-432989
    • (2013) Blood. , vol.121 , pp. 3692-3702
    • Mullally, A.1    Bruedigam, C.2    Poveromo, L.3    Heidel, F.H.4    Purdon, A.5    Vu, T.6    Austin, R.7    Heckl, D.8    Breyfogle, L.J.9    Kuhn, C.P.10
  • 23
    • 0028070714 scopus 로고
    • Functional role of type I and type II interferons in antiviral defense
    • Müller, U., U. Steinhoff, L.F. Reis, S. Hemmi, J. Pavlovic, R.M. Zinkernagel, and M. Aguet. 1994. Functional role of type I and type II interferons in antiviral defense. Science. 264:1918-1921. http://dx.doi.org/ 10.1126/science.8009221
    • (1994) Science. , vol.264 , pp. 1918-1921
    • Müller, U.1    Steinhoff, U.2    Reis, L.F.3    Hemmi, S.4    Pavlovic, J.5    Zinkernagel, R.M.6    Aguet, M.7
  • 25
    • 13844319184 scopus 로고    scopus 로고
    • Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
    • Opferman, J.T., H. Iwasaki, C.C. Ong, H. Suh, S. Mizuno, K. Akashi, and S.J. Korsmeyer. 2005. Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science. 307:1101-1104. http://dx.doi .org/10.1126/science.1106114
    • (2005) Science. , vol.307 , pp. 1101-1104
    • Opferman, J.T.1    Iwasaki, H.2    Ong, C.C.3    Suh, H.4    Mizuno, S.5    Akashi, K.6    Korsmeyer, S.J.7
  • 26
    • 38349132624 scopus 로고    scopus 로고
    • Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
    • Orford, K.W., and D.T. Scadden. 2008. Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nat. Rev. Genet. 9:115-128. http://dx.doi.org/10.1038/nrg2269
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 115-128
    • Orford, K.W.1    Scadden, D.T.2
  • 27
    • 67149128178 scopus 로고    scopus 로고
    • IFN-alpha wakes up sleeping hematopoietic stem cells
    • Passegué, E., and P. Ernst. 2009. IFN-alpha wakes up sleeping hematopoietic stem cells. Nat. Med. 15:612-613. http://dx.doi.org/10.1038/ nm0609-612
    • (2009) Nat. Med. , vol.15 , pp. 612-613
    • Passegué, E.1    Ernst, P.2
  • 28
    • 84855885803 scopus 로고    scopus 로고
    • Cell cycle regulation in hematopoietic stem cells
    • Pietras, E.M., M.R. Warr, and E. Passegué. 2011. Cell cycle regulation in hematopoietic stem cells. J. Cell Biol. 195:709-720. http://dx.doi .org/10.1083/jcb.201102131
    • (2011) J. Cell Biol. , vol.195 , pp. 709-720
    • Pietras, E.M.1    Warr, M.R.2    Passegué, E.3
  • 29
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I-and type-II-interferon-mediated signalling
    • Platanias, L.C. 2005. Mechanisms of type-I-and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5:375-386. http://dx.doi.org/10.1038/ nri1604
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 375-386
    • Platanias, L.C.1
  • 30
    • 63249095562 scopus 로고    scopus 로고
    • JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal
    • Santaguida, M., K. Schepers, B. King, A.J. Sabnis, E.C. Forsberg, J.L. Attema, B.S. Braun, and E. Passegué. 2009. JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal. Cancer Cell. 15:341-352. http://dx.doi.org/10.1016/j.ccr.2009.02.016
    • (2009) Cancer Cell. , vol.15 , pp. 341-352
    • Santaguida, M.1    Schepers, K.2    King, B.3    Sabnis, A.J.4    Forsberg, E.C.5    Attema, J.L.6    Braun, B.S.7    Passegué, E.8
  • 31
    • 67149091317 scopus 로고    scopus 로고
    • Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion
    • Sato, T., N. Onai, H. Yoshihara, F. Arai, T. Suda, and T. Ohteki. 2009. Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion. Nat. Med. 15:696-700. http://dx.doi.org/10.1038/nm.1973
    • (2009) Nat. Med. , vol.15 , pp. 696-700
    • Sato, T.1    Onai, N.2    Yoshihara, H.3    Arai, F.4    Suda, T.5    Ohteki, T.6
  • 32
    • 84858402081 scopus 로고    scopus 로고
    • Immunological reconstitution after autologous stem cell transplantation in patients with refractory systemic autoimmune diseases
    • Szodoray, P., L. Varoczy, G. Papp, S. Barath, B. Nakken, G. Szegedi, and M. Zeher. 2012. Immunological reconstitution after autologous stem cell transplantation in patients with refractory systemic autoimmune diseases. Scand. J. Rheumatol. 41:110-115. http://dx.doi.org/10.3109/ 03009742.2011.606788
    • (2012) Scand. J. Rheumatol. , vol.41 , pp. 110-115
    • Szodoray, P.1    Varoczy, L.2    Papp, G.3    Barath, S.4    Nakken, B.5    Szegedi, G.6    Zeher, M.7
  • 34
    • 0025854383 scopus 로고
    • Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Philadelphia chromosome-positive patients.
    • Talpaz, M., H. Kantarjian, R. Kurzrock, J.M. Trujillo, and J.U. Gutterman. 1991. Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Philadelphia chromosome-positive patients. Ann. Intern. Med. 114:532-538. http://dx.doi.org/10.7326/ 0003-4819-114-7-532
    • (1991) Ann. Intern. Med. , vol.114 , pp. 532-538
    • Talpaz, M.1    Kantarjian, H.2    Kurzrock, R.3    Trujillo, J.M.4    Gutterman, J.U.5
  • 35
    • 42649114059 scopus 로고    scopus 로고
    • The IRF family transcription factors in immunity and oncogenesis
    • Tamura, T., H. Yanai, D. Savitsky, and T. Taniguchi. 2008. The IRF family transcription factors in immunity and oncogenesis. Annu. Rev. Immunol. 26:535-584. http://dx.doi.org/10.1146/annurev.immunol.26.021607 .090400
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 36
    • 84859388606 scopus 로고    scopus 로고
    • Successes and failures of stem cell transplantation in autoimmune diseases
    • Tyndall, A. 2011. Successes and failures of stem cell transplantation in autoimmune diseases. Hematology (Am Soc Hematol Educ Program). 2011:280-284. http://dx.doi.org/10.1182/asheducation-2011.1.280
    • (2011) Hematology (Am Soc Hematol Educ Program). , vol.2011 , pp. 280-284
    • Tyndall, A.1
  • 37
    • 0037040869 scopus 로고    scopus 로고
    • Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-β on normal hematopoiesis
    • Verma, A., D.K. Deb, A. Sassano, S. Uddin, J. Varga, A. Wickrema, and L.C. Platanias. 2002. Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-β on normal hematopoiesis. J. Biol. Chem. 277:7726-7735. http://dx.doi.org/10.1074/jbc.M106640200
    • (2002) J. Biol. Chem. , vol.277 , pp. 7726-7735
    • Verma, A.1    Deb, D.K.2    Sassano, A.3    Uddin, S.4    Varga, J.5    Wickrema, A.6    Platanias, L.C.7
  • 40
    • 33747613351 scopus 로고    scopus 로고
    • Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
    • Yamazaki, S., A. Iwama, S.-I. Takayanagi, Y. Morita, K. Eto, H. Ema, and H. Nakauchi. 2006. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells. EMBO J. 25:3515-3523. http://dx.doi.org/10.1038/sj.emboj.7601236
    • (2006) EMBO J. , vol.25 , pp. 3515-3523
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.-I.3    Morita, Y.4    Eto, K.5    Ema, H.6    Nakauchi, H.7
  • 41
    • 60849093771 scopus 로고    scopus 로고
    • TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation
    • Yamazaki, S., A. Iwama, S. Takayanagi, K. Eto, H. Ema, and H. Nakauchi. 2009. TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation. Blood. 113:1250-1256.
    • (2009) Blood. , vol.113 , pp. 1250-1256
    • Yamazaki, S.1    Iwama, A.2    Takayanagi, S.3    Eto, K.4    Ema, H.5    Nakauchi, H.6
  • 43
    • 33947309693 scopus 로고    scopus 로고
    • p38 MAP kinase regulates stem cell apoptosis in human hematopoietic failure
    • Zhou, L., J. Opalinska, and A. Verma. 2007. p38 MAP kinase regulates stem cell apoptosis in human hematopoietic failure. Cell Cycle. 6:534-537. http://dx.doi.org/10.4161/cc.6.5.3921
    • (2007) Cell Cycle. , vol.6 , pp. 534-537
    • Zhou, L.1    Opalinska, J.2    Verma, A.3


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