HPLC-Q-TOF-MS Identification of Antioxidant and Antihypertensive Peptides Recovered from Cherry (Prunus cerasus L.) Subproducts

Journal of Agricultural and Food Chemistry

Volumn 63, Issue 5, 2015, Pages 1514-1520

  García, María Concepción ^a   Endermann, Jochan ^a   González García, Estefanía ^a   Marina, María Luisa ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

antihypertensive; antioxidant; cherry; MS identification; peptide; seed proteins

Indexed keywords

ANTIOXIDANTS; BIOINFORMATICS; FRUITS; INDUCTIVELY COUPLED PLASMA; MASS SPECTROMETRY; PEPTIDES; SUSTAINABLE DEVELOPMENT;

ANTIHYPERTENSIVE; ANTIHYPERTENSIVE PEPTIDES; BIOACTIVE PEPTIDES; BIOINFORMATICS TOOLS; CHERRY; ENVIRONMENTAL SUSTAINABILITY; PRUNUS CERASUS; SEED PROTEIN;

PROTEINS;

PRUNUS CERASUS;

ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; PEPTIDE; PLANT EXTRACT; VEGETABLE PROTEIN;

AMINO ACID SEQUENCE; CHEMISTRY; FRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; MOLECULAR GENETICS; PEPTIDE MAPPING; PRUNUS;

AMINO ACID SEQUENCE; ANTIHYPERTENSIVE AGENTS; ANTIOXIDANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FRUIT; HYDROLYSIS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PEPTIDES; PLANT EXTRACTS; PLANT PROTEINS; PRUNUS;

EID: 84922602558     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf505037p     Document Type: Article

References (22)

1. United Nations Environment Programme, http://www.unep.org, Jan. 13, 2014.
2. Rodríguez, G.; Lama, A.; Rodríguez, R.; Jiménez, A.; Guillén, R.; Fernández-Bolaños, J. Olive stone an attractive source of bioactive and valuable compounds Bioresour. Technol. 2008, 99, 5261-5269
3. Restrepo, M. Cleaner production in food industry Prod. + Limpia 2006, 1, 87-101
4. Panchaud, A.; Affolter, M.; Kussmann, M. Mass spectrometry for nutritional peptidomics: how to analyze food bioactives and their health effects J. Proteomics 2012, 75, 3546-3559
5. Lee, J.; Koo, N.; Min, D. B. Reactive oxygen species, aging, and antioxidative nutraceuticals Compr. Rev. Food Sci. Food Saf. 2004, 3, 21-33
6. Dhole, S. N.; Kuchekar, B. S. Comparative study of antihypertensive activity of telmisartan with telmisartan-hydroxypropyl-β-cyclodextrin inclusion complexes Pharm. Globale 2011, 2, 1-5
7. Sakat, S. S.; Wankhede, S. S.; Juvekar, A. R.; Mali, V. R.; Bodhankar, S. L. Antihypertensive effect of aqueous extract of Elaeocarpusganitrus Roxb. seeds in renal artery occluded hypertensive rats Int. J. Pharm. Technol. Res. 2009, 1, 779-782
8. Lobo, V.; Patil, A.; Phatak, A.; Chandra, N. Free radicals, antioxidants and functional foods: Impact on human health Pharmacogn. Rev. 2010, 4, 118-126
9. Sakanaka, S.; Tachibana, Y.; Ishihara, N.; Juneja, L. R. Antioxidant activity of egg-yolk protein hydrolysates in a linoleic acid oxidation system Food Chem. 2004, 86, 99-103
10. Sakanaka, S.; Tachibana, Y.; Ishihara, N.; Juneja, L. R. Antioxidant properties of casein calcium peptides and their effects on lipid oxidation in beef homogenates J. Agric. Food Chem. 2005, 53, 464-468
11. Puchalska, P.; Marina, M. L.; García, M. C. Isolation and characterization of peptides with antihypertensive activity in foodstuffs. Cri. Rev. Food Sci. Nutr., DOI: 10.1080/10408398.2012.664829.
12. Esteve, C.; Del Rio, C.; Marina, M. L.; García, M. C. First ultraperformance liquid chromatography based strategy for profiling intact proteins in complex matrices: application to the evaluation of the performance of olive (Olea europaea L.) stone proteins for cultivar fingerprinting J. Agric. Food Chem. 2010, 58, 8176-8182
13. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 1976, 72, 248-254
14. Wang, D.; Wang, L.; Zhu, F.; Zhu, J.; Chen, X. D.; Zou, L.; Saito, M.; Li, L. In vitro and in vivo study of the antioxidant activities of the aqueous extracts of Douchi (a traditional Chinese salt-fermented soybean food) Food Chem. 2008, 107, 1421-1428
15. Wiriyaphan, C.; Chitsomboon, B.; Yongsawadigul, J. Antioxidant activity of protein hydrolysates derived from threadfin bream surimi byproducts Food Chem. 2012, 132, 104-111
16. Ajibola, C. F.; Fashakin, J. B.; Fagbemi, T. N.; Aluko, R. E. Effect of peptide size on antioxidant properties of african yam bean seed (Sphenostylis stenocarpa) protein hydrolysate fractions Int. J. Mol. Sci. 2011, 12, 6685-6702
17. Chen, H. M.; Muramoto, K.; Yamauchi, F.; Nokihara, K. Antioxidant activity of design peptides based on the antioxidative peptide isolated from the digests of a soybean proteins J. Agric. Food Chem. 1996, 44, 2619-2623
18. Geng, F.; He, Y.; Yang, L.; Wang, Z. A rapid assay for angiotensin-converting enzyme activity using ultra-performance liquid chromatography-mass spectrometry Biomed. Chromatogr. 2010, 24, 312-317
19. González-García, E.; Marina, M. L.; García, M. C. Plum (Prunus Domestica L.) by-product as a new and cheap source of bioactive peptides: extraction method and peptides characterization. J. Funct. Foods, 2014, 11, 428 - 437.
20. Esteve, C.; Marina, M. L.; García, M. C. Novel strategy for the revalorization of olive (Olea europaea) residues based on the extraction of bioactive peptides Food Chem. 2015, 167, 272-280
21. Puchalska, P.; García, M. C.; Marina, M. L. Identification of native angiotensin-I converting enzyme inhibitory peptides in commercial soybean based infant formulas using HPLC-Q-TOF-MS Food Chem. 2014, 157, 62-69
22. Sarmadi, B. H.; Ismail, A. Antioxidative peptides from food proteins: a review Peptides 2010, 31, 1949-1956