Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging

Journal of the American College of Cardiology

Volumn 65, Issue 2, 2015, Pages 133-147

  Hariharan, Nirmala ^a   Quijada, Pearl ^a   Mohsin, Sadia ^a   Joyo, Anya ^a   Samse, Kaitlen ^a   Monsanto, Megan ^a   De La Torre, Andrea ^a   Avitabile, Daniele ^a,b   Ormachea, Lucia ^a   McGregor, Michael J ^a   Tsai, Emily J ^c   Sussman, Mark A ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Senescence; Signal transduction

Indexed keywords

MYC PROTEIN; NUCLEAR PROTEIN; NUCLEOSTEMIN; PROTEIN KINASE PIM 1; PROTEIN P16; PROTEIN P53; REGULATOR PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; NUCLEOSTEMIN PROTEIN, MOUSE;

ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARDIAC STEM CELL; CELL AGING; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL ISOLATION; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; FETAL STEM CELL; FETUS; HEART FUNCTION; HEART MUSCLE; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; KNOCKOUT MOUSE; MALE; MOUSE; MULTINUCLEAR CELL; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; REJUVENATION; TELOMERE SHORTENING; UPREGULATION; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; METABOLISM; PHYSIOLOGY; STEM CELL;

ANIMALS; CARRIER PROTEINS; CELL AGING; CELL DIFFERENTIATION; CELLS, CULTURED; HUMANS; MALE; MICE; MICE, KNOCKOUT; MYOCARDIUM; NUCLEAR PROTEINS; REJUVENATION; STEM CELLS;

EID: 84922600175     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.09.086     Document Type: Article

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