Formulation, stability and pharmacokinetics of sugar-based salmon calcitonin-loaded nanoporous/nanoparticulate microparticles (NPMPs) for inhalation

International Journal of Pharmaceutics

Volumn 483, Issue 1-2, 2015, Pages 6-18

  Amaro, Maria Inês ^a   Tewes, Frederic ^a,b   Gobbo, Oliviero ^a   Tajber, Lidia ^a   Corrigan, Owen I ^a   Ehrhardt, Carsten ^a   Healy, Anne Marie ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITÉ DE POITIERS   (France)

Author keywords

Inhalation; Non reducing sugars; Pharmacokinetics; Salmon calcitonin; Stability

Indexed keywords

NANOMATERIAL; NANOPARTICULATE MICROPARTICLE; RAFFINOSE; SALCATONIN; SUGAR; TREHALOSE; UNCLASSIFIED DRUG; CALCITONIN; CARBOHYDRATE; NANOPARTICLE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG HALF LIFE; DRUG STABILITY; DRY POWDER; IN VIVO STUDY; MALE; MEAN RESIDENCE TIME; NONHUMAN; PHYSICAL CHEMISTRY; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SPRAY DRYING; CHEMISTRY; DRY POWDER INHALER; INHALATIONAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; PARTICLE SIZE; POROSITY; SURFACE PROPERTY;

ADMINISTRATION, INHALATION; CALCITONIN; CARBOHYDRATES; CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; DRY POWDER INHALERS; NANOPARTICLES; PARTICLE SIZE; POROSITY; SURFACE PROPERTIES;

EID: 84922587412     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.02.003     Document Type: Article

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