Do co-spray dried excipients offer better lysozyme stabilisation than single excipients?

European Journal of Pharmaceutical Sciences

Volumn 33, Issue 3, 2008, Pages 294-305

  Hulse, Wendy L ^a   Forbes, Robert T ^a   Bonner, Michael C ^a   Getrost, Matthias ^b  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b Merck Biosciences Ltd   (United Kingdom)

Author keywords

Excipient mixtures; Lysozyme; Protein stabilisation; Spray drying; Stability study

Indexed keywords

EXCIPIENT; LYSOZYME; MANNITOL; SORBITOL; TREHALOSE;

ARTICLE; BIOLOGICAL ACTIVITY; COMPARATIVE STUDY; CRYSTALLIZATION; DEHYDRATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STABILITY; DRUG STORAGE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME STABILITY; ENZYME STRUCTURE; HUMIDITY; PRIORITY JOURNAL; PROTEIN STABILITY; RAMAN SPECTROMETRY; SOLID; SPRAY DRYING; STRUCTURE ANALYSIS; TEMPERATURE SENSITIVITY; THERMAL ANALYSIS; THERMOGRAVIMETRY; THERMOSTABILITY; X RAY POWDER DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; DRUG COMPOUNDING; DRUG STABILITY; EXCIPIENTS; MANNITOL; MICROCOCCUS; MURAMIDASE; SORBITOL; THERMOGRAVIMETRY; TREHALOSE; X-RAY DIFFRACTION;

EID: 39649088233     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2007.12.007     Document Type: Article

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